{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:57:20Z","timestamp":1792623440268,"version":"4.5.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["bmn.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Genetics &amp; Development"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.gde.2011.01.008","type":"journal-article","created":{"date-parts":[[2011,1,28]],"date-time":"2011-01-28T04:40:36Z","timestamp":1296189636000},"page":"354-361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Impact of induced pluripotent stem cells on the study of central nervous system disease"],"prefix":"10.1016","volume":"21","author":[{"given":"Paige E","family":"Cundiff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stewart A","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gde.2011.01.008_bib0005_1","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1126\/science.282.5391.1145","article-title":"Embryonic stem cell lines derived from human blastocysts","volume":"282","author":"Thomson","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.gde.2011.01.008_bib0010_1","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.cell.2007.11.019","article-title":"Induction of pluripotent stem cells from adult human fibroblasts by defined factors","volume":"131","author":"Takahashi","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0015","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/nature05944","article-title":"In vitro reprogramming of fibroblasts into a pluripotent es-cell-like state","volume":"448","author":"Wernig","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.gde.2011.01.008_bib0020_1","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1101\/gad.1963910","article-title":"Induced pluripotency: history, mechanisms, and applications","volume":"24","author":"Stadtfeld","year":"2010","journal-title":"Genes Dev"},{"key":"10.1016\/j.gde.2011.01.008_bib0025_1","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.cell.2010.10.008","article-title":"Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues","volume":"143","author":"Hanna","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0030","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.stem.2009.09.012","article-title":"A small-molecule inhibitor of tgf-beta signaling replaces sox2 in reprogramming by inducing nanog","volume":"5","author":"Ichida","year":"2009","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0035","doi-asserted-by":"crossref","first-page":"8912","DOI":"10.1073\/pnas.0903860106","article-title":"Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of klf4","volume":"106","author":"Lyssiotis","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0040","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1038\/nbt1483","article-title":"A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types","volume":"26","author":"Wernig","year":"2008","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.gde.2011.01.008_bib0045","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1038\/nature07061","article-title":"Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors","volume":"454","author":"Kim","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.gde.2011.01.008_bib0050","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/bit.22517","article-title":"Cell-free production of transducible transcription factors for nuclear reprogramming","volume":"104","author":"Yang","year":"2009","journal-title":"Biotechnol Bioeng"},{"key":"10.1016\/j.gde.2011.01.008_bib0055_1","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1038\/nature08592","article-title":"Direct cell reprogramming is a stochastic process amenable to acceleration","volume":"462","author":"Hanna","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.gde.2011.01.008_bib0060","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.stem.2009.03.005","article-title":"Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells","volume":"4","author":"Feng","year":"2009","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0065","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/ncb1827","article-title":"Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor esrrb","volume":"11","author":"Feng","year":"2009","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.gde.2011.01.008_bib0070","doi-asserted-by":"crossref","first-page":"e253","DOI":"10.1371\/journal.pbio.0060253","article-title":"Promotion of reprogramming to ground state pluripotency by signal inhibition","volume":"6","author":"Silva","year":"2008","journal-title":"PLoS Biol"},{"key":"10.1016\/j.gde.2011.01.008_bib0075_1","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.stem.2010.08.012","article-title":"Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mrna","volume":"7","author":"Warren","year":"2010","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0080","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/nmeth.1325","article-title":"Isolation of human ips cells using eos lentiviral vectors to select for pluripotency","volume":"6","author":"Hotta","year":"2009","journal-title":"Nat Methods"},{"key":"10.1016\/j.gde.2011.01.008_bib0085_1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.cell.2010.10.016","article-title":"A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells","volume":"143","author":"Marchetto","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0090","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.stem.2010.04.005","article-title":"Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells","volume":"6","author":"Urbach","year":"2010","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0095_1","doi-asserted-by":"crossref","first-page":"17668","DOI":"10.1073\/pnas.1004487107","article-title":"Induced pluripotent stem cell models of the genomic imprinting disorders angelman and prader-willi syndromes","volume":"107","author":"Chamberlain","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0100_1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/nature07677","article-title":"Induced pluripotent stem cells from a spinal muscular atrophy patient","volume":"457","author":"Ebert","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.gde.2011.01.008_bib0105","doi-asserted-by":"crossref","first-page":"R71","DOI":"10.1093\/hmg\/ddq159","article-title":"Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases","volume":"19","author":"Marchetto","year":"2010","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.gde.2011.01.008_bib0110_1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/nature08320","article-title":"Modelling pathogenesis and treatment of familial dysautonomia using patient-specific ipscs","volume":"461","author":"Lee","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.gde.2011.01.008_bib0115_1","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.cell.2008.07.041","article-title":"Disease-specific induced pluripotent stem cells","volume":"134","author":"Park","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0120","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/1096-8628(200022)97:2<147::AID-AJMG6>3.0.CO;2-O","article-title":"Rett syndrome: methyl-cpg-binding protein 2 mutations and phenotype-genotype correlations","volume":"97","author":"Amir","year":"2000","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.gde.2011.01.008_bib0125","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/13810","article-title":"Rett syndrome is caused by mutations in x-linked mecp2, encoding methyl-cpg-binding protein 2","volume":"23","author":"Amir","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.gde.2011.01.008_bib0130","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2217\/epi.09.13","article-title":"Evolving role of mecp2 in rett syndrome and autism","volume":"1","author":"Lasalle","year":"2009","journal-title":"Epigenomics"},{"key":"10.1016\/j.gde.2011.01.008_bib0135","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/aur.24","article-title":"Mecp2 promoter methylation and X chromosome inactivation in autism","volume":"1","author":"Nagarajan","year":"2008","journal-title":"Autism Res"},{"key":"10.1016\/j.gde.2011.01.008_bib0140","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/nbt.1530","article-title":"Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming","volume":"27","author":"Deng","year":"2009","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.gde.2011.01.008_bib0145","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.stem.2009.08.010","article-title":"Pluripotent stem cells and disease modeling","volume":"5","author":"Colman","year":"2009","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0150","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/embor.2009.142","article-title":"Induced pluripotent stem cells and the stability of the differentiated state","volume":"10","author":"Colman","year":"2009","journal-title":"EMBO Rep"},{"key":"10.1016\/j.gde.2011.01.008_bib0155_1","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nature09582","article-title":"Dysfunction in gaba signalling mediates autism-like stereotypies and rett syndrome phenotypes","volume":"468","author":"Chao","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.gde.2011.01.008_bib0160","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1086\/368263","article-title":"Tissue-specific reduction in splicing efficiency of ikbkap due to the major mutation associated with familial dysautonomia","volume":"72","author":"Cuajungco","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.gde.2011.01.008_bib0165","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.cell.2009.02.013","article-title":"Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors","volume":"136","author":"Soldner","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0170","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1126\/science.1158799","article-title":"Induced pluripotent stem cells generated from patients with als can be differentiated into motor neurons","volume":"321","author":"Dimos","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.gde.2011.01.008_bib0175","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/j.1600-0404.1991.tb05013.x","article-title":"Oxidative stress as a cause of parkinson's disease","volume":"136","author":"Jenner","year":"1991","journal-title":"Acta Neurol Scand Suppl"},{"key":"10.1016\/j.gde.2011.01.008_bib0180","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1006\/nbdi.2000.0319","article-title":"Oxidative stress and genetics in the pathogenesis of parkinson's disease","volume":"7","author":"Zhang","year":"2000","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.gde.2011.01.008_bib0185_1","doi-asserted-by":"crossref","first-page":"15921","DOI":"10.1073\/pnas.1010209107","article-title":"Differentiated parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in parkinsonian rats","volume":"107","author":"Hargus","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0190_1","doi-asserted-by":"crossref","first-page":"4335","DOI":"10.1073\/pnas.0910012107","article-title":"Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency","volume":"107","author":"Hu","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0195","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/nn1402","article-title":"Directed differentiation of telencephalic precursors from embryonic stem cells","volume":"8","author":"Watanabe","year":"2005","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.gde.2011.01.008_bib0200","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1038\/nprot.2009.157","article-title":"Generation of cortical neurons from mouse embryonic stem cells","volume":"4","author":"Gaspard","year":"2009","journal-title":"Nat Protoc"},{"key":"10.1016\/j.gde.2011.01.008_bib0205_1","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.stem.2008.09.002","article-title":"Self-organized formation of polarized cortical tissues from escs and its active manipulation by extrinsic signals","volume":"3","author":"Eiraku","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2011.01.008_bib0210_1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/nature07287","article-title":"An intrinsic mechanism of corticogenesis from embryonic stem cells","volume":"455","author":"Gaspard","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.gde.2011.01.008_bib0215","doi-asserted-by":"crossref","first-page":"5780","DOI":"10.1073\/pnas.0708704105","article-title":"Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells","volume":"105","author":"Kondo","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0220","doi-asserted-by":"crossref","first-page":"e283","DOI":"10.1371\/journal.pbio.0030283","article-title":"Niche-independent symmetrical self-renewal of a mammalian tissue stem cell","volume":"3","author":"Conti","year":"2005","journal-title":"PLoS Biol"},{"key":"10.1016\/j.gde.2011.01.008_bib0225","doi-asserted-by":"crossref","first-page":"4055","DOI":"10.1242\/dev.036624","article-title":"Coordination of sonic hedgehog and wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells","volume":"136","author":"Li","year":"2009","journal-title":"Development"},{"key":"10.1016\/j.gde.2011.01.008_bib0230_1","doi-asserted-by":"crossref","first-page":"4667","DOI":"10.1523\/JNEUROSCI.4255-09.2010","article-title":"Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells","volume":"30","author":"Maroof","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.gde.2011.01.008_bib0235","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.nbd.2009.02.007","article-title":"An optimized experimental strategy for efficient conversion of embryonic stem (es)-derived mouse neural stem (ns) cells into a nearly homogeneous mature neuronal population","volume":"34","author":"Spiliotopoulos","year":"2009","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.gde.2011.01.008_bib0240","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.expneurol.2009.03.032","article-title":"Derivation of homogeneous gabaergic neurons from mouse embryonic stem cells","volume":"217","author":"Chatzi","year":"2009","journal-title":"Exp Neurol"},{"key":"10.1016\/j.gde.2011.01.008_bib0245","doi-asserted-by":"crossref","first-page":"11796","DOI":"10.1073\/pnas.0803078105","article-title":"Minimization of exogenous signals in es cell culture induces rostral hypothalamic differentiation","volume":"105","author":"Wataya","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0250","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0896-6273(00)00083-0","article-title":"Induction of midbrain dopaminergic neurons from es cells by stromal cell-derived inducing activity","volume":"28","author":"Kawasaki","year":"2000","journal-title":"Neuron"},{"key":"10.1016\/j.gde.2011.01.008_bib0255","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1111\/j.1471-4159.2004.03006.x","article-title":"In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons","volume":"92","author":"Park","year":"2005","journal-title":"J Neurochem"},{"key":"10.1016\/j.gde.2011.01.008_bib0260","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.brainres.2006.10.022","article-title":"A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo","volume":"1127","author":"Iacovitti","year":"2007","journal-title":"Brain Res"},{"key":"10.1016\/j.gde.2011.01.008_bib0265","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.mcn.2010.06.017","article-title":"Differentiation of human es and parkinson's disease ips cells into ventral midbrain dopaminergic neurons requires a high activity form of shh, fgf8a and specific regionalization by retinoic acid","volume":"45","author":"Cooper","year":"2010","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.gde.2011.01.008_bib0270","doi-asserted-by":"crossref","first-page":"3392","DOI":"10.1073\/pnas.0712359105","article-title":"Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells","volume":"105","author":"Cho","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0275","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1111\/j.1471-4159.2007.04898.x","article-title":"Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons","volume":"103","author":"Ko","year":"2007","journal-title":"J Neurochem"},{"key":"10.1016\/j.gde.2011.01.008_bib0280","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.1073\/pnas.0610879104","article-title":"Differentiation of es cells into cerebellar neurons","volume":"104","author":"Salero","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0285","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.ydbio.2005.11.010","article-title":"Generation of cerebellar neuron precursors from embryonic stem cells","volume":"290","author":"Su","year":"2006","journal-title":"Dev Biol"},{"key":"10.1016\/j.gde.2011.01.008_bib0290","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1089\/scd.2009.0498","article-title":"Efficient differentiation of human embryonic stem cells into functional cerebellar-like cells","volume":"19","author":"Erceg","year":"2010","journal-title":"Stem Cells Dev"},{"key":"10.1016\/j.gde.2011.01.008_bib0295","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1634\/stemcells.2007-0097","article-title":"Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons","volume":"25","author":"Lee","year":"2007","journal-title":"Stem Cells"},{"key":"10.1016\/j.gde.2011.01.008_bib0300","doi-asserted-by":"crossref","first-page":"e2122","DOI":"10.1371\/journal.pone.0002122","article-title":"Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions","volume":"3","author":"Erceg","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.gde.2011.01.008_bib0305","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1006\/exnr.2001.7832","article-title":"Enrichment of neurons and neural precursors from human embryonic stem cells","volume":"172","author":"Carpenter","year":"2001","journal-title":"Exp Neurol"},{"key":"10.1016\/j.gde.2011.01.008_bib0310","doi-asserted-by":"crossref","first-page":"e6722","DOI":"10.1371\/journal.pone.0006722","article-title":"Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells","volume":"4","author":"Wada","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.gde.2011.01.008_bib0315","article-title":"Differentiation of embryonic stem cells into oligodendrocyte precursors","volume":"39","author":"Jiang","year":"2010","journal-title":"J Vis Exp"},{"key":"10.1016\/j.gde.2011.01.008_bib0320","first-page":"15","article-title":"Generation and characterization of oligodendrocytes from lineage-selectable embryonic stem cells in vitro","volume":"330","author":"Billon","year":"2006","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.gde.2011.01.008_bib0325","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1242\/jcs.00049","article-title":"Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse es cells","volume":"115","author":"Billon","year":"2002","journal-title":"J Cell Sci"},{"key":"10.1016\/j.gde.2011.01.008_bib0330","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3109\/00207450903585290","article-title":"Efficient differentiation of human embryonic stem cells into oligodendrocyte progenitors for application in a rat contusion model of spinal cord injury","volume":"120","author":"Kerr","year":"2010","journal-title":"Int J Neurosci"},{"key":"10.1016\/j.gde.2011.01.008_bib0335","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.mcn.2004.07.006","article-title":"Mecp2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions","volume":"27","author":"Kishi","year":"2004","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.gde.2011.01.008_bib0340","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1086\/345360","article-title":"Rett syndrome and mecp2: linking epigenetics and neuronal function","volume":"71","author":"Shahbazian","year":"2002","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.gde.2011.01.008_bib0345","first-page":"573","article-title":"Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases","volume":"80","author":"Swaab","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.gde.2011.01.008_bib0350","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/ng0997-75","article-title":"Imprinted expression of the murine angelman syndrome gene, ube3a, in hippocampal and purkinje neurons","volume":"17","author":"Albrecht","year":"1997","journal-title":"Nat Genet"},{"key":"10.1016\/j.gde.2011.01.008_bib0355","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/hmg\/ddm288","article-title":"The angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology","volume":"17","author":"Dindot","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.gde.2011.01.008_bib0360","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1101\/gad.1743709","article-title":"Bmi-1 cooperates with foxg1 to maintain neural stem cell self-renewal in the forebrain","volume":"23","author":"Fasano","year":"2009","journal-title":"Genes Dev"},{"key":"10.1016\/j.gde.2011.01.008_bib0365_1","doi-asserted-by":"crossref","first-page":"15472","DOI":"10.1073\/pnas.0900141106","article-title":"Reduction of seizures by transplantation of cortical gabaergic interneuron precursors into kv1.1 mutant mice","volume":"106","author":"Baraban","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2011.01.008_bib0370_1","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.stem.2010.01.004","article-title":"Embryonic mge precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-ohda-lesioned rats","volume":"6","author":"Martinez-Cerdeno","year":"2010","journal-title":"Cell Stem Cell"}],"container-title":["Current Opinion in Genetics &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X11000128?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X11000128?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T11:39:15Z","timestamp":1760701155000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959437X11000128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":74,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0959437X11000128"],"URL":"https:\/\/doi.org\/10.1016\/j.gde.2011.01.008","relation":{},"ISSN":["0959-437X"],"issn-type":[{"value":"0959-437X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of induced pluripotent stem cells on the study of central nervous system disease","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Genetics & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gde.2011.01.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}