{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:31:40Z","timestamp":1791351100366,"version":"4.3.1"},"reference-count":60,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["CA125453"],"award-info":[{"award-number":["CA125453"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["CA111691"],"award-info":[{"award-number":["CA111691"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AG033747"],"award-info":[{"award-number":["AG033747"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["AG036695"],"award-info":[{"award-number":["AG036695"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["K99HL114732"],"award-info":[{"award-number":["K99HL114732"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000900","name":"California Institute for Regenerative Medicine","doi-asserted-by":"crossref","award":["RB2-01497"],"award-info":[{"award-number":["RB2-01497"]}],"id":[{"id":"10.13039\/100000900","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["bmn.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Genetics &amp; Development"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.gde.2013.07.006","type":"journal-article","created":{"date-parts":[[2013,8,28]],"date-time":"2013-08-28T09:01:10Z","timestamp":1377680470000},"page":"526-533","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Understanding telomere diseases through analysis of patient-derived iPS cells"],"prefix":"10.1016","volume":"23","author":[{"given":"Luis FZ","family":"Batista","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven E","family":"Artandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gde.2013.07.006_bib0005","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1146\/annurev.genet.41.110306.130350","article-title":"How shelterin protects mammalian telomeres","volume":"41","author":"Palm","year":"2008","journal-title":"Annu Rev Genet"},{"key":"10.1016\/j.gde.2013.07.006_bib0010","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1126\/science.1218498","article-title":"Removal of shelterin reveals the telomere end-protection problem","volume":"336","author":"Sfeir","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.gde.2013.07.006_bib0015","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/nature02118","article-title":"A DNA damage checkpoint response in telomere-initiated senescence","volume":"426","author":"d\u2019Adda di Fagagna","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_bib0020","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/S0960-9822(03)00542-6","article-title":"DNA damage foci at dysfunctional telomeres","volume":"13","author":"Takai","year":"2003","journal-title":"Curr Biol"},{"key":"10.1016\/j.gde.2013.07.006_bib0025","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1126\/science.279.5349.349","article-title":"Extension of life-span by introduction of telomerase into normal human cells","volume":"279","author":"Bodnar","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.gde.2013.07.006_bib0030","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/carcin\/bgp268","article-title":"Telomeres and telomerase in cancer","volume":"31","author":"Artandi","year":"2010","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.gde.2013.07.006_bib0035","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0092-8674(00)80580-2","article-title":"Longevity, stress response, and cancer in aging telomerase-deficient mice","volume":"96","author":"Rudolph","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0040","doi-asserted-by":"crossref","first-page":"2950","DOI":"10.1093\/emboj\/18.11.2950","article-title":"Disease states associated with telomerase deficiency appear earlier in mice with short telomeres","volume":"18","author":"Herrera","year":"1999","journal-title":"EMBO J"},{"key":"10.1016\/j.gde.2013.07.006_bib0045","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/nrg3246","article-title":"The telomere syndromes","volume":"13","author":"Armanios","year":"2012","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.gde.2013.07.006_bib0050","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1097\/GIM.0b013e3181f415b5","article-title":"The genetics and clinical manifestations of telomere biology disorders","volume":"12","author":"Savage","year":"2010","journal-title":"Genet Med"},{"key":"10.1016\/j.gde.2013.07.006_sbref0055","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1002\/hep.24217","article-title":"Telomerase gene mutations are associated with cirrhosis formation","volume":"53","author":"Hartmann","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.gde.2013.07.006_sbref0060","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1002\/hep.24173","article-title":"Constitutional telomerase mutations are genetic risk factors for cirrhosis","volume":"53","author":"Calado","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.gde.2013.07.006_bib0065","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1365-2141.2010.08212.x","article-title":"Malignancies and survival patterns in the national cancer institute inherited bone marrow failure syndromes cohort study","volume":"150","author":"Alter","year":"2010","journal-title":"Br J Haematol"},{"key":"10.1016\/j.gde.2013.07.006_bib0070","doi-asserted-by":"crossref","first-page":"6549","DOI":"10.1182\/blood-2008-12-192880","article-title":"Cancer in dyskeratosis congenita","volume":"113","author":"Alter","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.gde.2013.07.006_bib0075","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0959-437X(99)00047-7","article-title":"A critical role for telomeres in suppressing and facilitating carcinogenesis","volume":"10","author":"Artandi","year":"2000","journal-title":"Curr Opin Genet Dev"},{"key":"10.1016\/j.gde.2013.07.006_bib0080","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0092-8674(00)80762-X","article-title":"P53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis","volume":"97","author":"Chin","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0085","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S1535-6108(02)00094-6","article-title":"Telomere dysfunction provokes regional amplification and deletion in cancer genomes","volume":"2","author":"O\u2019Hagan","year":"2002","journal-title":"Cancer Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0090","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1038\/nature05886","article-title":"Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers","volume":"447","author":"Maser","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_bib0095","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.ccr.2012.03.044","article-title":"Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells","volume":"21","author":"Davoli","year":"2012","journal-title":"Cancer Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0100","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cell.2010.01.031","article-title":"Persistent telomere damage induces bypass of mitosis and tetraploidy","volume":"141","author":"Davoli","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0105","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1056\/NEJMoa066157","article-title":"Telomerase mutations in families with idiopathic pulmonary fibrosis","volume":"356","author":"Armanios","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gde.2013.07.006_bib0110","doi-asserted-by":"crossref","first-page":"7552","DOI":"10.1073\/pnas.0701009104","article-title":"Adult-onset pulmonary fibrosis caused by mutations in telomerase","volume":"104","author":"Tsakiri","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2013.07.006_bib0115","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1056\/NEJMoa042980","article-title":"Mutations in tert, the gene for telomerase reverse transcriptase, in aplastic anemia","volume":"352","author":"Yamaguchi","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gde.2013.07.006_bib0120","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.bcmd.2004.12.008","article-title":"Mutations in the reverse transcriptase component of telomerase (tert) in patients with bone marrow failure","volume":"34","author":"Vulliamy","year":"2005","journal-title":"Blood Cells Mol Dis"},{"key":"10.1016\/j.gde.2013.07.006_bib0125","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1056\/NEJMra0903373","article-title":"Telomere diseases","volume":"361","author":"Calado","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gde.2013.07.006_bib0130","doi-asserted-by":"crossref","first-page":"3255","DOI":"10.1182\/blood.V91.9.3255","article-title":"Telomerase activity in candidate stem cells from fetal liver and adult bone marrow","volume":"91","author":"Yui","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.gde.2013.07.006_bib0135","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1074-7613(00)80316-7","article-title":"Telomerase activity in hematopoietic cells is associated with self-renewal potential","volume":"5","author":"Morrison","year":"1996","journal-title":"Immunity"},{"key":"10.1016\/j.gde.2013.07.006_bib0140","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1038\/emboj.2011.26","article-title":"Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes","volume":"30","author":"Schepers","year":"2011","journal-title":"EMBO J"},{"key":"10.1016\/j.gde.2013.07.006_bib0145","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/1523-1747.ep12285654","article-title":"Telomerase activity concentrates in the mitotically active segments of human hair follicles","volume":"108","author":"Ramirez","year":"1997","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.gde.2013.07.006_bib0150","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/33345","article-title":"Essential role of mouse telomerase in highly proliferative organs","volume":"392","author":"Lee","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_bib0155","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1182\/blood-2002-07-2334","article-title":"Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation","volume":"102","author":"Allsopp","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.gde.2013.07.006_bib0160","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.cell.2012.01.040","article-title":"A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage","volume":"148","author":"Wang","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0165","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/nature05862","article-title":"Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age","volume":"447","author":"Rossi","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_sbref0170","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.cell.2010.11.039","article-title":"Short telomeres and stem cell exhaustion model duchenne muscular dystrophy in mdx\/mtr mice","volume":"143","author":"Sacco","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0175","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1126\/science.282.5391.1145","article-title":"Embryonic stem cell lines derived from human blastocysts","volume":"282","author":"Thomson","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.gde.2013.07.006_sbref0180","doi-asserted-by":"crossref","DOI":"10.1038\/nature08792","article-title":"Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients","author":"Agarwal","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_sbref0185","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nature10084","article-title":"Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells","volume":"474","author":"Batista","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_bib0190","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1038\/nature08287","article-title":"A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity","volume":"460","author":"Marion","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_bib0195","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/990141","article-title":"A telomerase component is defective in the human disease dyskeratosis congenita","volume":"402","author":"Mitchell","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_bib0200","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1126\/science.1165357","article-title":"A human telomerase holoenzyme protein required for cajal body localization and telomere synthesis","volume":"323","author":"Venteicher","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.gde.2013.07.006_bib0205","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.molcel.2009.02.020","article-title":"A conserved wd40 protein binds the cajal body localization signal of scaRNP particles","volume":"34","author":"Tycowski","year":"2009","journal-title":"Mol Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0210","doi-asserted-by":"crossref","first-page":"2384","DOI":"10.1128\/MCB.00379-12","article-title":"Telomerase recruitment requires both TCAB1 and Cajal bodies independently","volume":"32","author":"Stern","year":"2012","journal-title":"Mol Cell Biol"},{"key":"10.1016\/j.gde.2013.07.006_bib0215","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1101\/gad.173922.111","article-title":"Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state","volume":"25","author":"Lapasset","year":"2011","journal-title":"Genes Dev"},{"key":"10.1016\/j.gde.2013.07.006_bib0220","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.stem.2008.12.010","article-title":"Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells","volume":"4","author":"Marion","year":"2009","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0225","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.stem.2008.02.001","article-title":"Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse","volume":"2","author":"Stadtfeld","year":"2008","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.gde.2013.07.006_bib0230","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.cancergen.2011.11.002","article-title":"The genetics of dyskeratosis congenita","volume":"204","author":"Mason","year":"2011","journal-title":"Cancer Genet"},{"key":"10.1016\/j.gde.2013.07.006_sbref0235","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1172\/JCI67146","article-title":"Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs","volume":"123","author":"Winkler","year":"2013","journal-title":"J Clin Investig"},{"key":"10.1016\/j.gde.2013.07.006_bib0240","doi-asserted-by":"crossref","first-page":"2848","DOI":"10.1101\/gad.1476206","article-title":"Telomerase rna level limits telomere maintenance in x-linked dyskeratosis congenita","volume":"20","author":"Wong","year":"2006","journal-title":"Genes Dev"},{"key":"10.1016\/j.gde.2013.07.006_bib0245","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1101\/gad.2006411","article-title":"Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita","volume":"25","author":"Zhong","year":"2011","journal-title":"Genes Dev"},{"key":"10.1016\/j.gde.2013.07.006_sbref0250","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.cell.2012.07.012","article-title":"TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends","volume":"150","author":"Zhong","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.gde.2013.07.006_sbref0255","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/nature11648","article-title":"The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity","volume":"492","author":"Nandakumar","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.gde.2013.07.006_bib0260","doi-asserted-by":"crossref","first-page":"8073","DOI":"10.1073\/pnas.0800042105","article-title":"Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita","volume":"105","author":"Vulliamy","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2013.07.006_bib0265","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1093\/hmg\/ddm111","article-title":"Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10","volume":"16","author":"Walne","year":"2007","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.gde.2013.07.006_bib0270","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ajhg.2007.10.004","article-title":"TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita","volume":"82","author":"Savage","year":"2008","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.gde.2013.07.006_bib0275","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00439-013-1265-8","article-title":"Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in dyskeratosis congenita","volume":"132","author":"Ballew","year":"2013","journal-title":"Hum Genet"},{"key":"10.1016\/j.gde.2013.07.006_bib0280","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.ajhg.2013.02.001","article-title":"Constitutional mutations in RTEL1 cause severe dyskeratosis congenita","volume":"92","author":"Walne","year":"2013","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.gde.2013.07.006_bib0285","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/ng.1084","article-title":"Mutations in CTC1, encoding conserved telomere maintenance component 1, cause coats plus","volume":"44","author":"Anderson","year":"2012","journal-title":"Nat Genet"},{"key":"10.1016\/j.gde.2013.07.006_sbref0290","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3324\/haematol.2011.055269","article-title":"Telomere length is associated with disease severity and declines with age in dyskeratosis congenita","volume":"97","author":"Alter","year":"2012","journal-title":"Haematologica"},{"key":"10.1016\/j.gde.2013.07.006_bib0295","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/ng1346","article-title":"Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC","volume":"36","author":"Vulliamy","year":"2004","journal-title":"Nat Genet"},{"key":"10.1016\/j.gde.2013.07.006_bib0300","doi-asserted-by":"crossref","first-page":"15960","DOI":"10.1073\/pnas.0508124102","article-title":"Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita","volume":"102","author":"Armanios","year":"2005","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Current Opinion in Genetics &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X13001056?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X13001056?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T11:43:14Z","timestamp":1760701394000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959437X13001056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":60,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0959437X13001056"],"URL":"https:\/\/doi.org\/10.1016\/j.gde.2013.07.006","relation":{},"ISSN":["0959-437X"],"issn-type":[{"value":"0959-437X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Understanding telomere diseases through analysis of patient-derived iPS cells","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Genetics & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gde.2013.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}