{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:17:22Z","timestamp":1790698642521,"version":"4.1.0"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000893","name":"Simons Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000893","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmn.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Genetics &amp; Development"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.gde.2020.05.042","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T02:51:21Z","timestamp":1594954281000},"page":"151-159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"special_numbering":"C","title":["Cortico-basal ganglia circuits underlying dysfunctional control of motor behaviors in neuropsychiatric disorders"],"prefix":"10.1016","volume":"65","author":[{"given":"Ana Mafalda","family":"Vicente","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela J","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui M","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gde.2020.05.042_bib0005","doi-asserted-by":"crossref","first-page":"e3454","DOI":"10.1136\/bmj.e3454","article-title":"Time to end the distinction between mental and neurological illnesses","volume":"344","author":"White","year":"2012","journal-title":"BMJ Br Med J"},{"key":"10.1016\/j.gde.2020.05.042_bib0010","first-page":"10","article-title":"Prevalence of spontaneous dyskinesia in schizophrenia","volume":"61","author":"Fenton","year":"2000","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0015","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1523\/JNEUROSCI.16-05-01936.1996","article-title":"A framework for mesencephalic dopamine systems based on predictive Hebbian learning","volume":"16","author":"Montague","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.gde.2020.05.042_bib0020","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1126\/science.275.5306.1593","article-title":"A neural substrate of prediction and reward","volume":"275","author":"Schultz","year":"1997","journal-title":"Science (80-)"},{"key":"10.1016\/j.gde.2020.05.042_bib0025","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1146\/annurev-neuro-072116-031109","article-title":"Neural circuitry of reward prediction error","volume":"40","author":"Watabe-Uchida","year":"2017","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0030","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nature09263","article-title":"Start\/stop signals emerge in nigrostriatal circuits during sequence learning","volume":"466","author":"Jin","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.gde.2020.05.042_bib0035","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/nature25457","article-title":"Dopamine neuron activity before action initiation gates and invigorates future movements","volume":"554","author":"da Silva","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.gde.2020.05.042_bib0040","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/nature18942","article-title":"Rapid signalling in distinct dopaminergic axons during locomotion and reward","volume":"535","author":"Howe","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.gde.2020.05.042_bib0045","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1126\/science.1160575","article-title":"Dichotomous dopaminergic control of striatal synaptic plasticity","volume":"321","author":"Shen","year":"2008","journal-title":"Science (80-)"},{"key":"10.1016\/j.gde.2020.05.042_bib0050","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0166-2236(89)90074-X","article-title":"The functional anatomy of basal ganglia disorders","volume":"12","author":"Albin","year":"1989","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0055","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/nature09159","article-title":"Regulation of parkinsonian motor behaviors by optogenetic control of basal ganglia circuitry","volume":"466","author":"Kravitz","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.gde.2020.05.042_bib0060","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/nature11846","article-title":"Concurrent activation of striatal direct and indirect pathways during action initiation","volume":"494","author":"Cui","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.gde.2020.05.042_sbref0065","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.cell.2016.06.032","article-title":"Complementary contributions of striatal projection pathways to action initiation and execution","volume":"166","author":"Tecuapetla","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.gde.2020.05.042_bib0070","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.neuron.2016.08.037","article-title":"Spatially compact neural clusters in the dorsal striatum encode locomotion relevant information","volume":"92","author":"Barbera","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.gde.2020.05.042_bib0075","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.neuron.2017.08.015","article-title":"The spatiotemporal organization of the striatum encodes action space","volume":"95","author":"Klaus","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.gde.2020.05.042_bib0080","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3389\/fnsys.2013.00122","article-title":"Computational models of basal-ganglia pathway functions: focus on functional neuroanatomy","volume":"7","author":"Schroll","year":"2013","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0085","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/nn.2261","article-title":"Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill","volume":"12","author":"Yin","year":"2009","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0090","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/nrn1919","article-title":"The role of the basal ganglia in habit formation","volume":"7","author":"Yin","year":"2006","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0095","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1126\/science.286.5445.1745","article-title":"Building Neural Representations of Habits","volume":"286","author":"Jog","year":"1999","journal-title":"Science (80-)"},{"key":"10.1016\/j.gde.2020.05.042_bib0100","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1146\/annurev.neuro.29.051605.112851","article-title":"Habits, rituals, and the evaluative brain","volume":"31","author":"Graybiel","year":"2008","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms3264","article-title":"Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions","volume":"4","author":"Gremel","year":"2013","journal-title":"Nat Commun"},{"key":"10.1016\/j.gde.2020.05.042_bib0110","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.neuron.2016.04.043","article-title":"Endocannabinoid modulation of orbitostriatal circuits gates habit formation","volume":"90","author":"Gremel","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.gde.2020.05.042_bib0115","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/(SICI)1098-2779(1998)4:2<80::AID-MRDD4>3.0.CO;2-0","article-title":"Repetitive behavior disorders in autism","volume":"4","author":"Lewis","year":"1998","journal-title":"Ment Retard Dev Disabil Res Rev"},{"key":"10.1016\/j.gde.2020.05.042_bib0120","doi-asserted-by":"crossref","DOI":"10.1212\/CON.0000000000000603","article-title":"Obsessive-compulsive disorder","volume":"24","author":"Richter","year":"2018","journal-title":"Contin Lifelong Learn Neurol"},{"key":"10.1016\/j.gde.2020.05.042_bib0125","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1038\/mp.2008.83","article-title":"Multiple rare SAPAP3 missense variants in trichotillomania and OCD","volume":"14","author":"Z\u00fcchner","year":"2009","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0130","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1038\/nature06104","article-title":"Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice","volume":"448","author":"Welch","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.gde.2020.05.042_bib0135","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.biopsych.2013.01.008","article-title":"Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder","volume":"75","author":"Wan","year":"2014","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0140","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1038\/nm.2125","article-title":"Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive\u2013like behaviors in mice","volume":"16","author":"Shmelkov","year":"2010","journal-title":"Nat Med"},{"key":"10.1016\/j.gde.2020.05.042_bib0145","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1001\/jamapsychiatry.2017.1567","article-title":"Inflammation in the neurocircuitry of obsessive-compulsive disorder","volume":"74","author":"Attwells","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0150","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1017\/S0033291716003305","article-title":"Increased fronto-striatal reward prediction errors moderate decision making in obsessive\u2013compulsive disorder","volume":"47","author":"Hauser","year":"2017","journal-title":"Psychol Med"},{"key":"10.1016\/j.gde.2020.05.042_bib0155","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1007\/s00213-019-05292-2","article-title":"Dopaminergic drug treatment remediates exaggerated cingulate prediction error responses in obsessive-compulsive disorder","volume":"236","author":"Murray","year":"2019","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.gde.2020.05.042_bib0160","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1038\/s41386-018-0307-2","article-title":"Impaired instrumental reversal learning is associated with increased medial prefrontal cortex activity in Sapap3 knockout mouse model of compulsive behavior","volume":"44","author":"Manning","year":"2019","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.gde.2020.05.042_sbref0165","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuron.2019.01.046","article-title":"Obsessive-compulsive disorder: puzzles and prospects","volume":"102","author":"Robbins","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.gde.2020.05.042_bib0170","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1002\/jnr.24594","article-title":"The two-step task, avoidance, and OCD","volume":"98","author":"Geramita","year":"2020","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.gde.2020.05.042_bib0175","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-48637-9","article-title":"Aberrant habit formation in the Sapap3-knockout mouse model of obsessive-compulsive disorder","volume":"9","author":"Hadjas","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.gde.2020.05.042_bib0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.nlm.2020.107162","article-title":"Instrumental learning in a mouse model for obsessive-compulsive disorder: Impaired habit formation in Sapap3 mutants","volume":"168","author":"Ehmer","year":"2020","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.gde.2020.05.042_bib0185","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.neuroscience.2016.07.030","article-title":"Cognitive inflexibility in obsessive-compulsive disorder","volume":"345","author":"Gruner","year":"2017","journal-title":"Neuroscience"},{"key":"10.1016\/j.gde.2020.05.042_sbref0190","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1126\/science.1234733","article-title":"Repeated cortico-striatal stimulation generates persistent OCD-like behavior","volume":"340","author":"Ahmari","year":"2013","journal-title":"Science (80-)"},{"key":"10.1016\/j.gde.2020.05.042_sbref0195","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1126\/science.1232380","article-title":"Optogenetic stimulation of lateral orbitofrontostriatal pathway suppresses compulsive behaviors","volume":"340","author":"Burgui\u00e8re","year":"2013","journal-title":"Science (80-)"},{"key":"10.1016\/j.gde.2020.05.042_bib0200","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.cell.2015.07.014","article-title":"Intact-brain analyses reveal distinct information carried by SNc dopamine subcircuits","volume":"162","author":"Lerner","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.gde.2020.05.042_bib0205","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.biopsych.2013.02.002","article-title":"Enhanced avoidance habits in obsessive-compulsive disorder","volume":"75","author":"Gillan","year":"2014","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0210","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1176\/appi.ajp.2014.14040525","article-title":"Functional neuroimaging of avoidance habits in obsessive-compulsive disorder","volume":"172","author":"Gillan","year":"2014","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0215","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3758\/s13415-015-0347-6","article-title":"Model-based learning protects against forming habits","volume":"15","author":"Gillan","year":"2015","journal-title":"Cogn Affect Behav Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0220","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3389\/fnint.2017.00023","article-title":"Lever insertion as a salient stimulus promoting insensitivity to outcome devaluation","volume":"11","author":"Vandaele","year":"2017","journal-title":"Front Integr Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0225","series-title":"Dopamine Signaling in the Dorsomedial Striatum Promotes Compulsive Behavior","author":"Seiler","year":"2020"},{"key":"10.1016\/j.gde.2020.05.042_bib0230","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1034\/j.1601-183X.2003.00037.x","article-title":"Model of autism: increased ratio of excitation\/inhibition in key neural systems","volume":"2","author":"Rubenstein","year":"2003","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.gde.2020.05.042_bib0235","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1159\/000478725","article-title":"A dopamine hypothesis of autism spectrum disorder","volume":"39","author":"Pav\u0103l","year":"2017","journal-title":"Dev Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0240","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ejphar.2017.07.025","article-title":"Early-life risperidone enhances locomotor responses to amphetamine during adulthood","volume":"812","author":"Lee Stubbeman","year":"2017","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.gde.2020.05.042_bib0245","doi-asserted-by":"crossref","first-page":"3407","DOI":"10.1172\/JCI127411","article-title":"Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors","volume":"129","author":"DiCarlo","year":"2019","journal-title":"J Clin Invest"},{"key":"10.1016\/j.gde.2020.05.042_bib0250","article-title":"Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism","volume":"7","author":"Wang","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.gde.2020.05.042_bib0255","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/s41398-018-0142-6","article-title":"Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors","volume":"8","author":"Bey","year":"2018","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_sbref0260","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nature09965","article-title":"Shank3 mutant mice display autistic-like behaviours and striatal dysfunction","volume":"472","author":"Pe\u00e7a","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.gde.2020.05.042_bib0265","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.neuron.2012.03.009","article-title":"Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice","volume":"74","author":"Michalon","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.gde.2020.05.042_bib0270","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1038\/mp.2016.30","article-title":"Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice","volume":"22","author":"Vicidomini","year":"2017","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0275","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/nn.3911","article-title":"Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p.2 microdeletion","volume":"18","author":"Tian","year":"2015","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0280","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1038\/nrn2851","article-title":"Behavioural phenotyping assays for mouse models of autism","volume":"11","author":"Silverman","year":"2010","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0285","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1152\/jn.2001.86.5.2405","article-title":"Activation of Group I mGluRs is necessary for induction of long-term depression at striatal synapses","volume":"86","author":"Sung","year":"2001","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.gde.2020.05.042_bib0290","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.neures.2017.09.007","article-title":"Striatonigral direct pathway activation is sufficient to induce repetitive behaviors","volume":"132","author":"Bouchekioua","year":"2018","journal-title":"Neurosci Res"},{"key":"10.1016\/j.gde.2020.05.042_bib0295","doi-asserted-by":"crossref","first-page":"5658","DOI":"10.1007\/s12035-017-0770-5","article-title":"Excessive D1 dopamine receptor activation in the dorsal striatum promotes autistic-like behaviors","volume":"55","author":"Lee","year":"2018","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.gde.2020.05.042_bib0300","doi-asserted-by":"crossref","first-page":"79","DOI":"10.5607\/en.2016.25.2.79","article-title":"Reversal of an unconditioned behavioral preference for specific food pellets by intervention of whisker sensory inputs","volume":"25","author":"Kim","year":"2016","journal-title":"Exp Neurobiol"},{"key":"10.1016\/j.gde.2020.05.042_bib0305","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s13041-014-0077-7","article-title":"Adenylyl cyclase-5 in the dorsal striatum function as a molecular switch for the generation of behavioral preferences for cue-directed food choices","volume":"7","author":"Kim","year":"2014","journal-title":"Mol Brain"},{"key":"10.1016\/j.gde.2020.05.042_bib0310","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.neuron.2013.05.014","article-title":"Differential innervation of direct- and indirect-pathway striatal projection neurons","volume":"79","author":"Wall","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.gde.2020.05.042_bib0315","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/aur.1901","article-title":"The adenosine A2A receptor agonist, CGS 21680, attenuates a probabilistic reversal learning deficit and elevated grooming behavior in BTBR mice","volume":"11","author":"Amodeo","year":"2018","journal-title":"Autism Res"},{"key":"10.1016\/j.gde.2020.05.042_bib0320","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.pbb.2019.04.006","article-title":"Reduction of repetitive behavior by co-administration of adenosine receptor agonists in C58 mice","volume":"181","author":"Lewis","year":"2019","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.gde.2020.05.042_bib0325","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1172\/JCI87997","article-title":"Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism","volume":"127","author":"Wang","year":"2017","journal-title":"J Clin Invest"},{"key":"10.1016\/j.gde.2020.05.042_bib0330","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/mp.2017.184","article-title":"Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders","volume":"23","author":"Grissom","year":"2018","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_sbref0335","first-page":"1077","article-title":"Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome","volume":"7","author":"Portmann","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.gde.2020.05.042_bib0340","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.cortex.2020.02.010","article-title":"Common neuronal mechanisms underlying tics and hyperactivity","volume":"127","author":"Israelashvili","year":"2020","journal-title":"Cortex"},{"key":"10.1016\/j.gde.2020.05.042_bib0345","doi-asserted-by":"crossref","first-page":"13307","DOI":"10.1073\/pnas.0502624102","article-title":"Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome","volume":"102","author":"Kalanithi","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2020.05.042_bib0350","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/cne.22206","article-title":"Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome","volume":"518","author":"Kataoka","year":"2010","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.gde.2020.05.042_bib0355","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.biopsych.2017.01.020","article-title":"Targeted interneuron depletion in the dorsal striatum produces autism-like behavioral abnormalities in male but not female mice","volume":"82","author":"Rapanelli","year":"2017","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.gde.2020.05.042_bib0360","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0140-6736(19)33004-1","article-title":"Attention-deficit hyperactivity disorder","volume":"395","author":"Posner","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.gde.2020.05.042_bib0365","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.neuroscience.2016.05.040","article-title":"Components of motor deficiencies in ADHD and possible interventions","volume":"378","author":"Dahan","year":"2018","journal-title":"Neuroscience"},{"key":"10.1016\/j.gde.2020.05.042_bib0370","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1080\/02701367.2002.10608987","article-title":"Arm movement control: differences between children with and without attention deficit hyperactivity disorder","volume":"73","author":"Yan","year":"2002","journal-title":"Res Q Exerc Sport"},{"key":"10.1016\/j.gde.2020.05.042_bib0375","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1111\/j.1469-8749.2001.tb00157.x","article-title":"Is increased D2 receptor availability associated with response to stimulant medication in ADHD","volume":"43","author":"Ilgin","year":"2001","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.gde.2020.05.042_bib0380","doi-asserted-by":"crossref","first-page":"11043","DOI":"10.1523\/JNEUROSCI.1682-10.2010","article-title":"Role of aberrant striatal dopamine D1 receptor\/cAMP\/protein kinase A\/DARPP32 signaling in the paradoxical calming effect of amphetamine","volume":"30","author":"Napolitano","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0385","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.nbd.2006.12.011","article-title":"D2-like dopamine receptors mediate the response to amphetamine in a mouse model of ADHD","volume":"26","author":"Fan","year":"2007","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.gde.2020.05.042_bib0390","doi-asserted-by":"crossref","first-page":"17076","DOI":"10.1073\/pnas.1114042108","article-title":"Dosage-dependent phenotypes in models of 16p.2 lesions found in autism","volume":"108","author":"Horev","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.gde.2020.05.042_bib0395","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0134572","article-title":"Comprehensive analysis of the 16p11.2 deletion and null Cntnap2 mouse models of autism spectrum disorder","volume":"10","author":"Brunner","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.gde.2020.05.042_bib0400","first-page":"1","article-title":"Modeling restricted repetitive behavior in animals","volume":"S1:006","author":"Bechard","year":"2012","journal-title":"Autism"},{"key":"10.1016\/j.gde.2020.05.042_bib0405","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1037\/bne0000348","article-title":"Differential consequences of habitual responding in a mouse model of repetitive behavior","volume":"134","author":"Curry-Pochy","year":"2020","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.gde.2020.05.042_bib0410","article-title":"Individual differences in stereotypy and neuron subtype translatome with TrkB deletion","author":"Engeln","year":"2020","journal-title":"Mol Psychiatry"}],"container-title":["Current Opinion in Genetics &amp; Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X20301027?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X20301027?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T12:02:05Z","timestamp":1760702525000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959437X20301027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":82,"alternative-id":["S0959437X20301027"],"URL":"https:\/\/doi.org\/10.1016\/j.gde.2020.05.042","relation":{},"ISSN":["0959-437X"],"issn-type":[{"value":"0959-437X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cortico-basal ganglia circuits underlying dysfunctional control of motor behaviors in neuropsychiatric disorders","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Genetics & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gde.2020.05.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}