{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T21:10:14Z","timestamp":1778879414394,"version":"3.51.4"},"reference-count":70,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"NIH National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM124684"],"award-info":[{"award-number":["R35GM124684"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Current Opinion in Genetics & Development"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.gde.2025.102348","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T03:16:46Z","timestamp":1745551006000},"page":"102348","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Paternal effects on telomere integrity during the sperm-to-embryo transition"],"prefix":"10.1016","volume":"93","author":[{"given":"Sung-Ya","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4311-7535","authenticated-orcid":false,"given":"Mia T","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gde.2025.102348_bib1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/ng0501-10","article-title":"Packaging paternal chromosomes with protamine","volume":"28","author":"Braun","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.gde.2025.102348_bib2","series-title":"The Development of Drosophila melanogaster","first-page":"71","article-title":"Spermatogenesis","author":"Fuller","year":"1993"},{"key":"10.1016\/j.gde.2025.102348_bib3","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.150076","article-title":"The intimate genetics of Drosophila fertilization","volume":"5","author":"Loppin","year":"2015","journal-title":"Open Biol"},{"key":"10.1016\/j.gde.2025.102348_sbref4","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/s41586-024-07885-0","article-title":"Sperm-origin paternal effects on root stem cell niche differentiation","volume":"634","author":"Cheng","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.gde.2025.102348_sbref5","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1126\/science.adh0037","article-title":"Histone removal in sperm protects paternal chromosomes from premature division at fertilization","volume":"382","author":"Dubruille","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.gde.2025.102348_bib6","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1016\/j.cub.2010.11.013","article-title":"Specialization of a Drosophila capping protein essential for the protection of sperm telomeres","volume":"20","author":"Dubruille","year":"2010","journal-title":"Curr Biol"},{"key":"10.1016\/j.gde.2025.102348_bib7","doi-asserted-by":"crossref","first-page":"4932","DOI":"10.1073\/pnas.1016792108","article-title":"Paternal imprint essential for the inheritance of telomere identity in Drosophila","volume":"108","author":"Gao","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.gde.2025.102348_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1004317","article-title":"Paternal poly (ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression","volume":"10","author":"Ihara","year":"2014","journal-title":"PLoS Genet"},{"key":"10.1016\/j.gde.2025.102348_sbref9","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1126\/science.adk9469","article-title":"Prophage proteins alter long noncoding RNA and DNA of developing sperm to induce a paternal-effect lethality","volume":"383","author":"Kaur","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.gde.2025.102348_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1001434","article-title":"Transgenerational propagation and quantitative maintenance of paternal centromeres depends on Cid\/Cenp-A presence in Drosophila sperm","volume":"10","author":"Raychaudhuri","year":"2012","journal-title":"PLoS Biol"},{"key":"10.1016\/j.gde.2025.102348_sbref11","doi-asserted-by":"crossref","first-page":"6668","DOI":"10.1093\/nar\/gkad479","article-title":"Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin","volume":"51","author":"Sakashita","year":"2023","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.gde.2025.102348_bib12","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1534\/genetics.115.182436","article-title":"The deadbeat paternal effect of uncapped sperm telomeres on cell cycle progression and chromosome behavior in Drosophila melanogaster","volume":"203","author":"Yamaki","year":"2016","journal-title":"Genetics"},{"key":"10.1016\/j.gde.2025.102348_bib13","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1101\/gad.1346005","article-title":"Shelterin: the protein complex that shapes and safeguards human telomeres","volume":"19","author":"de Lange","year":"2005","journal-title":"Genes Dev"},{"key":"10.1016\/j.gde.2025.102348_bib14","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1146\/annurev.bi.65.070196.002005","article-title":"Telomere length regulation","volume":"65","author":"Greider","year":"1996","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/j.gde.2025.102348_bib15","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1038\/ng1633","article-title":"XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer","volume":"37","author":"Munoz","year":"2005","journal-title":"Nat Genet"},{"key":"10.1016\/j.gde.2025.102348_bib16","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0022-5193(73)90198-7","article-title":"A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon","volume":"41","author":"Olovnikov","year":"1973","journal-title":"J Theor Biol"},{"key":"10.1016\/j.gde.2025.102348_bib17","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.molcel.2005.02.035","article-title":"Telomere-end processing the terminal nucleotides of human chromosomes","volume":"18","author":"Sfeir","year":"2005","journal-title":"Mol Cell"},{"key":"10.1016\/j.gde.2025.102348_bib18","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/newbio239197a0","article-title":"Origin of concatemeric T7 DNA","volume":"239","author":"Watson","year":"1972","journal-title":"Nat N Biol"},{"key":"10.1016\/j.gde.2025.102348_bib19","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/337331a0","article-title":"A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis","volume":"337","author":"Greider","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.gde.2025.102348_bib20","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/0092-8674(87)90576-9","article-title":"The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity","volume":"51","author":"Greider","year":"1987","journal-title":"Cell"},{"key":"10.1016\/j.gde.2025.102348_bib21","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0092-8674(85)90170-9","article-title":"Identification of a specific telomere terminal transferase activity in Tetrahymena extracts","volume":"43","author":"Greider","year":"1985","journal-title":"Cell"},{"key":"10.1016\/j.gde.2025.102348_bib22","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s00412-015-0528-7","article-title":"Telomerase lost?","volume":"125","author":"Mason","year":"2016","journal-title":"Chromosoma"},{"key":"10.1016\/j.gde.2025.102348_bib23","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1146\/annurev.genet.38.072902.093115","article-title":"Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres","volume":"37","author":"Pardue","year":"2003","journal-title":"Annu Rev Genet"},{"key":"10.1016\/j.gde.2025.102348_bib24","doi-asserted-by":"crossref","first-page":"383","DOI":"10.4161\/nucl.2.5.17873","article-title":"Terminin: a protein complex that mediates epigenetic maintenance of Drosophila telomeres","volume":"2","author":"Raffa","year":"2011","journal-title":"Nucleus"},{"key":"10.1016\/j.gde.2025.102348_bib25","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/emboj\/20.5.1173","article-title":"Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13","volume":"20","author":"Grandin","year":"2001","journal-title":"EMBO J"},{"key":"10.1016\/j.gde.2025.102348_bib26","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/bies.950180103","article-title":"Endless quest","volume":"18","author":"Holliday","year":"1996","journal-title":"Bioessays"},{"key":"10.1016\/j.gde.2025.102348_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gde.2020.01.002","article-title":"Telomere maintenance mechanisms in cancer: telomerase, ALT or lack thereof","volume":"60","author":"Claude","year":"2020","journal-title":"Curr Opin Genet Dev"},{"key":"10.1016\/j.gde.2025.102348_bib28","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.4161\/cc.10.7.15071","article-title":"Epigenetic maintenance of telomere identity in Drosophila: buckle up for the sperm ride","volume":"10","author":"Dubruille","year":"2011","journal-title":"Cell Cycle"},{"key":"10.1016\/j.gde.2025.102348_bib29","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1007\/s00018-013-1469-z","article-title":"If the cap fits, wear it: an overview of telomeric structures over evolution","volume":"71","author":"Fulcher","year":"2014","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.gde.2025.102348_bib30","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1083\/jcb.151.7.1591","article-title":"Human sperm telomere-binding complex involves histone H2B and secures telomere membrane attachment","volume":"151","author":"Gineitis","year":"2000","journal-title":"J Cell Biol"},{"key":"10.1016\/j.gde.2025.102348_bib31","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s43032-024-01714-5","article-title":"Perspective in the mechanisms for repairing sperm DNA damage","volume":"32","author":"Li","year":"2025","journal-title":"Reprod Sci"},{"key":"10.1016\/j.gde.2025.102348_bib32","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1093\/hmg\/ddn090","article-title":"DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation","volume":"17","author":"Derijck","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.gde.2025.102348_bib33","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1093\/genetics\/140.1.219","article-title":"Genetic characterization of ms (3) K81, a paternal effect gene of Drosophila melanogaster","volume":"140","author":"Yasuda","year":"1995","journal-title":"Genetics"},{"key":"10.1016\/j.gde.2025.102348_bib34","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.cub.2004.12.071","article-title":"Origin and neofunctionalization of a Drosophila paternal effect gene essential for zygote viability","volume":"15","author":"Loppin","year":"2005","journal-title":"Curr Biol"},{"key":"10.1016\/j.gde.2025.102348_bib35","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.ygeno.2004.06.001","article-title":"Novel human testis-specific histone H2B encoded by the interrupted gene on the X chromosome","volume":"84","author":"Churikov","year":"2004","journal-title":"Genomics"},{"key":"10.1016\/j.gde.2025.102348_bib36","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1095\/biolreprod62.2.340","article-title":"Identification and characterization of a bovine sperm protein that binds specifically to single-stranded telomeric deoxyribonucleic acid","volume":"62","author":"Kozik","year":"2000","journal-title":"Biol Reprod"},{"key":"10.1016\/j.gde.2025.102348_bib37","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/emboj.2009.394","article-title":"HipHop interacts with HOAP and HP1 to protect Drosophila telomeres in a sequence-independent manner","volume":"29","author":"Gao","year":"2010","journal-title":"EMBO J"},{"key":"10.1016\/j.gde.2025.102348_bib38","doi-asserted-by":"crossref","DOI":"10.1126\/science.abk2432","article-title":"Fly Cell Atlas: a single-nucleus transcriptomic atlas of the adult fruit fly","volume":"375","author":"Li","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.gde.2025.102348_bib39","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1242\/jcs.167825","article-title":"Protection of Drosophila chromosome ends through minimal telomere capping","volume":"128","author":"Dubruille","year":"2015","journal-title":"J Cell Sci"},{"key":"10.1016\/j.gde.2025.102348_bib40","doi-asserted-by":"crossref","DOI":"10.26508\/lsa.202000992","article-title":"Gametic specialization of centromeric histone paralogs in Drosophila virilis","volume":"4","author":"Kursel","year":"2021","journal-title":"Life Sci Alliance"},{"key":"10.1016\/j.gde.2025.102348_bib41","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/excr.1997.3482","article-title":"Telomere-telomere interactions and candidate telomere binding protein(s) in mammalian sperm cells","volume":"232","author":"Zalensky","year":"1997","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.gde.2025.102348_bib42","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/BF00357684","article-title":"Well-defined genome architecture in the human sperm nucleus","volume":"103","author":"Zalensky","year":"1995","journal-title":"Chromosoma"},{"key":"10.1016\/j.gde.2025.102348_bib43","doi-asserted-by":"crossref","first-page":"4541","DOI":"10.1242\/jcs.02581","article-title":"Chromosome architecture in the decondensing human sperm nucleus","volume":"118","author":"Mudrak","year":"2005","journal-title":"J Cell Sci"},{"key":"10.1016\/j.gde.2025.102348_bib44","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1111\/j.1582-4934.2009.00830.x","article-title":"Functional polymorphism in H2BFWT-5\u2032UTR is associated with susceptibility to male infertility","volume":"13","author":"Lee","year":"2009","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.gde.2025.102348_bib45","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3109\/1354750X.2012.677066","article-title":"Relationship of SNP of H2BFWT gene to male infertility in a Chinese population with idiopathic spermatogenesis impairment","volume":"17","author":"Ying","year":"2012","journal-title":"Biomarkers"},{"key":"10.1016\/j.gde.2025.102348_bib46","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/andr.12464","article-title":"Association between two common transitions of H2BFWT gene and male infertility: a case-control, meta, and structural analysis","volume":"6","author":"Teimouri","year":"2018","journal-title":"Andrology"},{"key":"10.1016\/j.gde.2025.102348_bib47","doi-asserted-by":"crossref","DOI":"10.1111\/and.12805","article-title":"Association of the c.-9C>T and c.368A>G transitions in H2BFWT gene with male infertility in an Iranian population","volume":"50","author":"Rafatmanesh","year":"2018","journal-title":"Andrologia"},{"key":"10.1016\/j.gde.2025.102348_bib48","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.0040037","article-title":"Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm","volume":"4","author":"Kimura","year":"2008","journal-title":"PLoS Genet"},{"key":"10.1016\/j.gde.2025.102348_bib49","doi-asserted-by":"crossref","first-page":"12135","DOI":"10.1073\/pnas.0702703104","article-title":"Telomere length is paternally inherited and is associated with parental lifespan","volume":"104","author":"Njajou","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.gde.2025.102348_bib50","doi-asserted-by":"crossref","first-page":"16374","DOI":"10.1073\/pnas.0501724102","article-title":"Telomere length and heredity: indications of paternal inheritance","volume":"102","author":"Nordfjall","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.gde.2025.102348_bib51","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/ejhg.2009.178","article-title":"Large-scale parent-child comparison confirms a strong paternal influence on telomere length","volume":"18","author":"Nordfjall","year":"2010","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.gde.2025.102348_bib52","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1038\/ejhg.2012.303","article-title":"Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect","volume":"21","author":"Broer","year":"2013","journal-title":"Eur J Hum Genet"},{"key":"10.1016\/j.gde.2025.102348_bib53","doi-asserted-by":"crossref","first-page":"354","DOI":"10.18632\/aging.203810","article-title":"Telomere length is maternally inherited and associated with lipid metabolism in Chinese population","volume":"14","author":"Guo","year":"2022","journal-title":"Aging"},{"key":"10.1016\/j.gde.2025.102348_bib54","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1474-9728.2005.00144.x","article-title":"Paternal age is positively linked to telomere length of children","volume":"4","author":"Unryn","year":"2005","journal-title":"Aging Cell"},{"key":"10.1016\/j.gde.2025.102348_bib55","doi-asserted-by":"crossref","first-page":"3097","DOI":"10.1093\/hmg\/ddm271","article-title":"Paternal age at birth is an important determinant of offspring telomere length","volume":"16","author":"De Meyer","year":"2007","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.gde.2025.102348_bib56","article-title":"Older paternal ages and grandpaternal ages at conception predict longer telomeres in human descendants","volume":"286","author":"Eisenberg","year":"2019","journal-title":"Proc Biol Sci"},{"key":"10.1016\/j.gde.2025.102348_bib57","doi-asserted-by":"crossref","first-page":"10251","DOI":"10.1073\/pnas.1202092109","article-title":"Delayed paternal age of reproduction in humans is associated with longer telomeres across two generations of descendants","volume":"109","author":"Eisenberg","year":"2012","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.gde.2025.102348_bib58","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/ajpa.23109","article-title":"Paternal and grandpaternal ages at conception and descendant telomere lengths in chimpanzees and humans","volume":"162","author":"Eisenberg","year":"2017","journal-title":"Am J Phys Anthr"},{"key":"10.1016\/j.gde.2025.102348_bib59","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1007\/s10815-015-0574-3","article-title":"A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity, as well as increasing mean telomere length in human spermatozoa with advancing age","volume":"32","author":"Antunes","year":"2015","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.gde.2025.102348_bib60","doi-asserted-by":"crossref","DOI":"10.1186\/s13039-016-0224-1","article-title":"The paradox of longer sperm telomeres in older men's testes: a birth-cohort effect caused by transgenerational telomere erosion in the female germline","volume":"9","author":"Stindl","year":"2016","journal-title":"Mol Cytogenet"},{"key":"10.1016\/j.gde.2025.102348_bib61","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/925121","article-title":"Telomere length reprogramming in embryos and stem cells","volume":"2014","author":"Kalmbach","year":"2014","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.gde.2025.102348_bib62","doi-asserted-by":"crossref","first-page":"8034","DOI":"10.1073\/pnas.0402400101","article-title":"Telomere length is reset during early mammalian embryogenesis","volume":"101","author":"Schaetzlein","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.gde.2025.102348_bib63","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1038\/ncb1664","article-title":"Telomere lengthening early in development","volume":"9","author":"Liu","year":"2007","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.gde.2025.102348_bib64","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.molcel.2011.03.020","article-title":"Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions","volume":"42","author":"Zhao","year":"2011","journal-title":"Mol Cell"},{"key":"10.1016\/j.gde.2025.102348_bib65","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nrg2763","article-title":"Alternative lengthening of telomeres: models, mechanisms and implications","volume":"11","author":"Cesare","year":"2010","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.gde.2025.102348_bib66","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003017","article-title":"Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling","volume":"8","author":"Xu","year":"2012","journal-title":"PLoS Genet"},{"key":"10.1016\/j.gde.2025.102348_sbref67","article-title":"A parent-of-origin effect on embryonic telomere elongation determines telomere length inheritance","author":"Jeon","year":"2025","journal-title":"bioRxiv"},{"key":"10.1016\/j.gde.2025.102348_bib68","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2012.00143","article-title":"Dynamic alterations in the paternal epigenetic landscape following fertilization","volume":"3","author":"Jenkins","year":"2012","journal-title":"Front Genet"},{"key":"10.1016\/j.gde.2025.102348_bib69","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1093\/humrep\/des362","article-title":"Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos","volume":"28","author":"Mertzanidou","year":"2013","journal-title":"Hum Reprod"},{"key":"10.1016\/j.gde.2025.102348_bib70","doi-asserted-by":"crossref","DOI":"10.1186\/1477-7827-12-105","article-title":"Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage","volume":"12","author":"Chow","year":"2014","journal-title":"Reprod Biol Endocrinol"}],"container-title":["Current Opinion in Genetics & Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X25000401?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959437X25000401?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:19:18Z","timestamp":1778876358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959437X25000401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":70,"alternative-id":["S0959437X25000401"],"URL":"https:\/\/doi.org\/10.1016\/j.gde.2025.102348","relation":{},"ISSN":["0959-437X"],"issn-type":[{"value":"0959-437X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Paternal effects on telomere integrity during the sperm-to-embryo transition","name":"articletitle","label":"Article Title"},{"value":"Current Opinion in Genetics & Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gde.2025.102348","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"102348"}}