{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T15:04:52Z","timestamp":1761836692819,"version":"build-2065373602"},"reference-count":5,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T00:00:00Z","timestamp":1743120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genes & Diseases"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.gendis.2025.101620","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T04:56:57Z","timestamp":1744347417000},"page":"101620","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bioinformatic validation and machine learning based exploration of B cells-related gene signatures in the context of strategies for precision therapy to acute myeloid leukemia"],"prefix":"10.1016","volume":"13","author":[{"given":"Yongyu","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiehua","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9783-6954","authenticated-orcid":false,"given":"Jianchao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiansheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yequan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruilin","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gendis.2025.101620_bib1","doi-asserted-by":"crossref","first-page":"3073","DOI":"10.3892\/ol.2015.3707","article-title":"Abnormal methylation status of FBXW10 and SMPD3, and associations with clinical characteristics in clear cell renal cell carcinoma","volume":"10","author":"Wang","year":"2015","journal-title":"Oncol Lett"},{"key":"10.1016\/j.gendis.2025.101620_bib2","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.jcmgh.2023.05.007","article-title":"Activation of sphingomyelin phosphodiesterase 3 in liver regeneration impedes the progression of colorectal cancer liver metastasis via exosome-bound intercellular transfer of ceramides","volume":"16","author":"Li","year":"2023","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"10.1016\/j.gendis.2025.101620_bib3","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1002\/mc.23720","article-title":"Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma","volume":"63","author":"Zhang","year":"2024","journal-title":"Mol Carcinog"},{"key":"10.1016\/j.gendis.2025.101620_bib4","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1007\/s10517-018-4074-1","article-title":"TNF\u03b1-Induced expression of transport protein genes in HUVEC cells is associated with enhanced expression of transcription factor genes RELB and NFKB2 of the non-canonical NF-\u03baB pathway","volume":"164","author":"Knyazev","year":"2018","journal-title":"Bull Exp Biol Med"},{"key":"10.1016\/j.gendis.2025.101620_bib5","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1158\/2159-8290.CD-22-0535","article-title":"Targeting UGCG overcomes resistance to lysosomal autophagy inhibition","volume":"13","author":"Jain","year":"2023","journal-title":"Cancer Discov"}],"container-title":["Genes & Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352304225001096?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352304225001096?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T15:00:38Z","timestamp":1761836438000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352304225001096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":5,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S2352304225001096"],"URL":"https:\/\/doi.org\/10.1016\/j.gendis.2025.101620","relation":{},"ISSN":["2352-3042"],"issn-type":[{"type":"print","value":"2352-3042"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bioinformatic validation and machine learning based exploration of B cells-related gene signatures in the context of strategies for precision therapy to acute myeloid leukemia","name":"articletitle","label":"Article Title"},{"value":"Genes & Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gendis.2025.101620","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd\u00e9","name":"copyright","label":"Copyright"}],"article-number":"101620"}}