{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T07:35:09Z","timestamp":1767857709823,"version":"3.49.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:00Z","timestamp":1172707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gene"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1016\/j.gene.2006.11.004","type":"journal-article","created":{"date-parts":[[2006,11,20]],"date-time":"2006-11-20T15:44:16Z","timestamp":1164037456000},"page":"174-185","source":"Crossref","is-referenced-by-count":33,"title":["The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour"],"prefix":"10.1016","volume":"389","author":[{"given":"Franz","family":"Vauti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobias","family":"Goller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Beine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lore","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Klopstock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine M.","family":"H\u00f6lter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Wurst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmut","family":"Fuchs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Gailus-Durner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin Hrab\u00e9","family":"de Angelis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Henning","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2006.11.004_bib1","first-page":"405","article-title":"Bioinformatic analyses of the tRNA: (guanine 26, N2,N2)-dimethyltransferase (Trm1) family","volume":"4","author":"Bujnicki","year":"2002","journal-title":"J. Mol. Microbiol. Biotechnol."},{"key":"10.1016\/j.gene.2006.11.004_bib2","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.1093\/nar\/26.16.3753","article-title":"The tRNA(guanine-26,N2-N2) methyltransferase (Trm1) from the hyperthermophilic archaeon Pyrococcus furiosus: cloning, sequencing of the gene and its expression in Escherichia coli","volume":"26","author":"Constantinesco","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2006.11.004_bib3","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0006-8993(98)01258-X","article-title":"Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests","volume":"835","author":"Crawley","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.gene.2006.11.004_bib4","first-page":"9703","article-title":"Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae","volume":"261","author":"Ellis","year":"1986","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.gene.2006.11.004_bib5","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/nmeth0605-403","article-title":"Introducing the German Mouse Clinic: open access platform for standardized phenotyping","volume":"2","author":"Gailus-Durner","year":"2005","journal-title":"Nat. Methods"},{"key":"10.1016\/j.gene.2006.11.004_bib6","doi-asserted-by":"crossref","first-page":"4780","DOI":"10.1093\/emboj\/17.16.4780","article-title":"Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2","volume":"17","author":"Gerber","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.gene.2006.11.004_bib7","doi-asserted-by":"crossref","first-page":"9918","DOI":"10.1073\/pnas.1633296100","article-title":"A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome","volume":"100","author":"Hansen","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.gene.2006.11.004_bib8","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/BF00401402","article-title":"Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse","volume":"13","author":"Irwin","year":"1968","journal-title":"Psychopharmacologia"},{"key":"10.1016\/j.gene.2006.11.004_bib9","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.2042-7158.1968.tb09743.x","article-title":"The quantitative measurement of motor inco-ordination in naive mice using an accelerating rotarod","volume":"20","author":"Jones","year":"1968","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.gene.2006.11.004_bib10","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1078\/0940-2993-00301","article-title":"Behavioral phenotyping of mice in pharmacological and toxicological research","volume":"55","author":"Karl","year":"2003","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.gene.2006.11.004_bib11","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1093\/nar\/28.18.3445","article-title":"The human tRNA(m(2)(2)G(26))dimethyltransferase: functional expression and characterization of a cloned hTRM1 gene","volume":"28","author":"Liu","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2006.11.004_bib12","doi-asserted-by":"crossref","first-page":"5102","DOI":"10.1093\/nar\/26.22.5102","article-title":"Point and deletion mutations eliminate one or both methyl group transfers catalysed by the yeast TRM1 encoded tRNA (m22G26)dimethyltransferase","volume":"26","author":"Liu","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2006.11.004_bib13","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0378-1119(98)00550-2","article-title":"Caenorhabditis elegans ZC376.5 encodes a tRNA (m2\/2G(26))dimethyltransferance in which (246)arginine is important for the enzyme activity","volume":"226","author":"Liu","year":"1999","journal-title":"Gene"},{"key":"10.1016\/j.gene.2006.11.004_bib14","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0955-0674(97)80006-3","article-title":"Mammalian RNA-dependent deaminases and edited mRNAs","volume":"9","author":"Maas","year":"1997","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.gene.2006.11.004_bib15","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/90074","article-title":"Functional analysis of secreted and transmembrane proteins critical to mouse development","volume":"28","author":"Mitchell","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2006.11.004_bib16","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1017\/S1355838299982201","article-title":"Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme","volume":"5","author":"Motorin","year":"1999","journal-title":"RNA"},{"key":"10.1016\/j.gene.2006.11.004_bib17","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0014-5793(99)01679-8","article-title":"The tRNA N2,N2-dimethylguanosine-26 methyltransferase encoded by gene trm1 increases efficiency of suppression of an ochre codon in Schizosaccharomyces pombe","volume":"464","author":"Niederberger","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1016\/j.gene.2006.11.004_bib18","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3758\/BF03195393","article-title":"The modified hole board as a differential screen for behavior in rodents","volume":"33","author":"Ohl","year":"2001","journal-title":"Behav. Res. Meth. Instrum. Comput."},{"key":"10.1016\/j.gene.2006.11.004_bib27","series-title":"R: A language and environment for statistical computing","isbn-type":"print","author":"R Development Core Team","year":"2004","ISBN":"https:\/\/id.crossref.org\/isbn\/3900051070"},{"key":"10.1016\/j.gene.2006.11.004_bib19","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1093\/nar\/14.3.1131","article-title":"A single tRNA (guanine)-methyltransferase from Tetrahymena with both mono- and di-methylating activity","volume":"14","author":"Reinhart","year":"1986","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2006.11.004_bib20","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s003359900551","article-title":"Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment","volume":"8","author":"Rogers","year":"1997","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.gene.2006.11.004_bib21","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jneumeth.2006.04.002","article-title":"Systematic, standardized and comprehensive neurological phenotyping of inbred mice strains in the German Mouse Clinic","volume":"157","author":"Schneider","year":"2006","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.gene.2006.11.004_bib22","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/geno.2001.6500","article-title":"Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus","volume":"73","author":"Sood","year":"2001","journal-title":"Genomics"},{"key":"10.1016\/j.gene.2006.11.004_bib23","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1093\/nar\/26.1.148","article-title":"Compilation of tRNA sequences and sequences of tRNA genes","volume":"26","author":"Sprinzl","year":"1998","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2006.11.004_bib24","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/nar\/28.2.383","article-title":"ADEPTs: information necessary for subcellular distribution of eukaryotic sorting isozymes resides in domains missing from eubacterial and archaeal counterparts","volume":"28","author":"Stanford","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2006.11.004_bib25","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1021\/bi981880l","article-title":"Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli","volume":"38","author":"Tscherne","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.gene.2006.11.004_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/71622","article-title":"Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells","volume":"24","author":"Wiles","year":"2000","journal-title":"Nat. Genet."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111906007050?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111906007050?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T11:26:19Z","timestamp":1547205979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111906007050"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["S0378111906007050"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2006.11.004","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}