{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T20:40:01Z","timestamp":1714941601691},"reference-count":40,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81171614","31100917"],"award-info":[{"award-number":["81171614","31100917"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"crossref","award":["Y2090694","Y2081093"],"award-info":[{"award-number":["Y2090694","Y2081093"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Science and Technology Foundation of Zhejiang Province, China","award":["2008C23074"],"award-info":[{"award-number":["2008C23074"]}]},{"name":"Foundation of Science and Technology Innovation Team of Zhejiang Province, China","award":["2010R50048"],"award-info":[{"award-number":["2010R50048"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gene"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.gene.2013.01.050","type":"journal-article","created":{"date-parts":[[2013,2,9]],"date-time":"2013-02-09T06:32:17Z","timestamp":1360391537000},"page":"60-66","source":"Crossref","is-referenced-by-count":6,"title":["Insights into the evolution of gene organization and multidrug resistance from Klebsiella pneumoniae plasmid pKF3-140"],"prefix":"10.1016","volume":"519","author":[{"given":"Jie","family":"Bai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junrong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanmei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinsong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peizhen","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueying","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yali","family":"Xi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Ying","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liyan","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinyu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiyu","family":"Bao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tieli","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2013.01.050_bb0005","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1556\/AMicr.58.2011.4.11","article-title":"Diversity of aminoglycoside modifying enzyme genes among multidrug resistant Acinetobacter baumannii genotypes isolated from nosocomial infections in Tehran hospitals and their association with class 1 integrons","volume":"58","author":"Asadollahi","year":"2011","journal-title":"Acta Microbiol. Immunol. Hung."},{"key":"10.1016\/j.gene.2013.01.050_bb0010","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/jac\/46.1.87","article-title":"Two new gene cassettes, dfr17 (for trimethoprim resistance) and aadA4 (for spectinomycin\/streptomycin resistance), inserted in an Escherichia coli class 1 integron","volume":"46","author":"Chang","year":"2000","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0015","doi-asserted-by":"crossref","first-page":"5977","DOI":"10.1073\/pnas.0600938103","article-title":"Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach","volume":"103","author":"Chen","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.gene.2013.01.050_bb0020","doi-asserted-by":"crossref","first-page":"3861","DOI":"10.1128\/AAC.00456-06","article-title":"Complete nucleotide sequence of pK245, a 98-kilobase plasmid conferring quinolone resistance and extended-spectrum-beta-lactamase activity in a clinical Klebsiella pneumoniae isolate","volume":"50","author":"Chen","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0025","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.plasmid.2009.10.003","article-title":"Complete sequence of pEC14_114, a highly conserved IncFIB\/FIIA plasmid associated with uropathogenic Escherichia coli cystitis strains","volume":"63","author":"DebRoy","year":"2010","journal-title":"Plasmid"},{"key":"10.1016\/j.gene.2013.01.050_bb0030","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1128\/MMBR.58.2.162-210.1994","article-title":"Analysis of the sequence and gene products of the transfer region of the F sex factor","volume":"58","author":"Frost","year":"1994","journal-title":"Microbiol. Rev."},{"key":"10.1016\/j.gene.2013.01.050_bb0035","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1006\/plas.1993.1020","article-title":"RepFIB: a basic replicon of large plasmids","volume":"29","author":"Gibbs","year":"1993","journal-title":"Plasmid"},{"key":"10.1016\/j.gene.2013.01.050_bb0040","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1128\/AAC.45.3.723-726.2001","article-title":"Incidence of class 1 and 2 integrases in clinical and commensal bacteria from livestock, companion animals, and exotics","volume":"45","author":"Goldstein","year":"2001","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0045","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1093\/nar\/gkg254","article-title":"ZCURVE: a new system for recognizing protein-coding genes in bacterial and archaeal genomes","volume":"31","author":"Guo","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2013.01.050_bb0050","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.pt.2004.08.006","article-title":"The origins of antimalarial drug resistance","volume":"20","author":"Hastings","year":"2004","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.gene.2013.01.050_bb0055","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1093\/jac\/31.5.637","article-title":"Development of a specific probe for the aminoglycoside-(3)-N-acetyltransferase resistance gene","volume":"31","author":"Ho","year":"1993","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0060","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0147-619X(85)90052-6","article-title":"Nucleotide sequence analysis of a gene encoding a streptomycin\/spectinomycin adenylyltransferase","volume":"13","author":"Hollingshead","year":"1985","journal-title":"Plasmid"},{"key":"10.1016\/j.gene.2013.01.050_bb0065","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/jac\/28.3.333","article-title":"Characterization of two aminoglycoside-(3)-N-acetyltransferase genes and assay as epidemiological probes","volume":"28","author":"Javier Teran","year":"1991","journal-title":"J. Antimicrob. Chemother."},{"issue":"Suppl. 1","key":"10.1016\/j.gene.2013.01.050_bb0070","first-page":"30","article-title":"Clinical and microbiological characteristics of hospital infections in the neonatal intensive care unit","volume":"52","author":"Jurczak","year":"2007","journal-title":"Adv. Med. Sci."},{"key":"10.1016\/j.gene.2013.01.050_bb0080","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S1016-8478(23)10983-6","article-title":"Nucleotide sequence, expression and transcriptional analysis of the Escherichia coli mphK gene encoding macrolide-phosphotransferase K","volume":"6","author":"Kim","year":"1996","journal-title":"Mol. Cells"},{"key":"10.1016\/j.gene.2013.01.050_bb0075","doi-asserted-by":"crossref","first-page":"6964","DOI":"10.1074\/jbc.M513257200","article-title":"Hydrolysis of ATP by aminoglycoside 3\u2032-phosphotransferases: an unexpected cost to bacteria for harboring an antibiotic resistance enzyme","volume":"281","author":"Kim","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.gene.2013.01.050_bb0085","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1111\/j.1572-0241.2005.40310.x","article-title":"Pyogenic liver abscess with a focus on Klebsiella pneumoniae as a primary pathogen: an emerging disease with unique clinical characteristics","volume":"100","author":"Lederman","year":"2005","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.gene.2013.01.050_bb0090","doi-asserted-by":"crossref","first-page":"S122","DOI":"10.1038\/nm1145","article-title":"Antibacterial resistance worldwide: causes, challenges and responses","volume":"10","author":"Levy","year":"2004","journal-title":"Nat. Med."},{"key":"10.1016\/j.gene.2013.01.050_bb0095","doi-asserted-by":"crossref","first-page":"D443","DOI":"10.1093\/nar\/gkn656","article-title":"ARDB\u2014Antibiotic Resistance Genes Database","volume":"37","author":"Liu","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2013.01.050_bb0100","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1038\/nsb1195-1018","article-title":"A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site","volume":"2","author":"Narayana","year":"1995","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.gene.2013.01.050_bb0105","doi-asserted-by":"crossref","first-page":"5407","DOI":"10.1074\/jbc.274.9.5407","article-title":"A family of S-methylmethionine-dependent thiol\/selenol methyltransferases. Role in selenium tolerance and evolutionary relation","volume":"274","author":"Neuhierl","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.gene.2013.01.050_bb0110","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1574-6968.2001.tb10498.x","article-title":"Recovery of new integron classes from environmental DNA","volume":"195","author":"Nield","year":"2001","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.gene.2013.01.050_bb0115","doi-asserted-by":"crossref","first-page":"5052","DOI":"10.1128\/JB.182.18.5052-5058.2000","article-title":"Regulation of transcription of the mph(A) gene for macrolide 2\u2032-phosphotransferase I in Escherichia coli: characterization of the regulatory gene mphR(A)","volume":"182","author":"Noguchi","year":"2000","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.gene.2013.01.050_bb0120","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1128\/AAC.01540-07","article-title":"Sequence of conjugative plasmid pIP1206 mediating resistance to aminoglycosides by 16S rRNA methylation and to hydrophilic fluoroquinolones by efflux","volume":"52","author":"Perichon","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0125","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1128\/CMR.11.4.589","article-title":"Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors","volume":"11","author":"Podschun","year":"1998","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.gene.2013.01.050_bb0130","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1128\/AAC.32.11.1684","article-title":"RSF1010 and a conjugative plasmid contain sulII, one of two known genes for plasmid-borne sulfonamide resistance dihydropteroate synthase","volume":"32","author":"Radstrom","year":"1988","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0135","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1128\/AAC.35.9.1840","article-title":"Genetic analyses of sulfonamide resistance and its dissemination in gram-negative bacteria illustrate new aspects of R plasmid evolution","volume":"35","author":"Radstrom","year":"1991","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0140","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1093\/nar\/gkg274","article-title":"A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes","volume":"31","author":"Roberts","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2013.01.050_bb0145","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.1128\/AAC.46.11.3422-3427.2002","article-title":"Complete nucleotide sequence of Klebsiella pneumoniae multiresistance plasmid pJHCMW1","volume":"46","author":"Sarno","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0150","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1146\/annurev.biophys.33.110502.133613","article-title":"Structure, dynamics, and catalytic function of dihydrofolate reductase","volume":"33","author":"Schnell","year":"2004","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"10.1016\/j.gene.2013.01.050_bb0155","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1093\/jac\/dkn397","article-title":"Complete nucleotide sequence of pKP96, a 67,850bp multiresistance plasmid encoding qnrA1, aac(6\u2032)-Ib-cr and blaCTX-M-24 from Klebsiella pneumoniae","volume":"62","author":"Shen","year":"2008","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.gene.2013.01.050_bb0160","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1128\/MMBR.00020-10","article-title":"Mobility of plasmids","volume":"74","author":"Smillie","year":"2010","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.gene.2013.01.050_bb0165","doi-asserted-by":"crossref","first-page":"e1800","DOI":"10.1371\/journal.pone.0001800","article-title":"Klebsiella pneumoniae multiresistance plasmid pMET1: similarity with the Yersinia pestis plasmid pCRY and integrative conjugative elements","volume":"3","author":"Soler Bistue","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.gene.2013.01.050_bb0170","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1093\/molbev\/msm092","article-title":"MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0","volume":"24","author":"Tamura","year":"2007","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.gene.2013.01.050_bb0175","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1128\/JB.181.2.662-665.1999","article-title":"S-methylmethionine metabolism in Escherichia coli","volume":"181","author":"Thanbichler","year":"1999","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.gene.2013.01.050_bb0180","doi-asserted-by":"crossref","first-page":"13944","DOI":"10.1073\/pnas.94.25.13944","article-title":"Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum","volume":"94","author":"Triglia","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.gene.2013.01.050_bb0185","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/1471-2105-10-123","article-title":"FlyPhy: a phylogenomic analysis platform for Drosophila genes and gene families","volume":"10","author":"Wu","year":"2009","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.gene.2013.01.050_bb0190","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/bioinformatics\/btn092","article-title":"PlasmoGF: an integrated system for comparative genomics and phylogenetic analysis of Plasmodium gene families","volume":"24","author":"Xu","year":"2008","journal-title":"Bioinformatics"},{"key":"10.1016\/j.gene.2013.01.050_bb0195","doi-asserted-by":"crossref","first-page":"e8601","DOI":"10.1371\/journal.pone.0008601","article-title":"Sequence analysis of pKF3-70 in Klebsiella pneumoniae: probable origin from R100-like plasmid of Escherichia coli","volume":"5","author":"Yi","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.gene.2013.01.050_bb0200","doi-asserted-by":"crossref","first-page":"e10141","DOI":"10.1371\/journal.pone.0010141","article-title":"Sequencing and genetic variation of multidrug resistance plasmids in Klebsiella pneumoniae","volume":"5","author":"Zhao","year":"2010","journal-title":"PLoS One"}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111913001236?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111913001236?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T19:32:50Z","timestamp":1714937570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111913001236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0378111913001236"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2013.01.050","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}