{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:03:07Z","timestamp":1772064187614,"version":"3.50.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gene"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.gene.2013.03.044","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T05:48:10Z","timestamp":1363844890000},"page":"129-135","source":"Crossref","is-referenced-by-count":11,"title":["Enzymatic analysis of biomarkers for the monitoring of Gaucher patients in Colombia"],"prefix":"10.1016","volume":"521","author":[{"given":"Natalia","family":"Pacheco","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Uribe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2013.03.044_bb0040","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1098\/rstb.2003.1273","article-title":"Biochemistry of glycosphingolipid storage disorders: implications for therapeutic intervention","volume":"358","author":"Aerts","year":"2003","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.gene.2013.03.044_bb0185","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s10545-011-9308-6","article-title":"Biomarkers in the diagnosis of lysosomal storage disorders: proteins, lipids, and inhibodies","volume":"34","author":"Aerts","year":"2011","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.gene.2013.03.044_bb0155","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0009-8981(03)00089-5","article-title":"Plasma chitotriosidase activity in acute Plasmodium falciparum malaria","volume":"331","author":"Barone","year":"2003","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.gene.2013.03.044_bb0050","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1007\/s10354-010-0814-1","article-title":"Laboratory and genetic evaluation of Gaucher disease","volume":"160","author":"Bodamer","year":"2010","journal-title":"Wien. Med. Wochenschr."},{"key":"10.1016\/j.gene.2013.03.044_bb0190","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.cccn.2004.02.018","article-title":"Correlation of surrogate markers of Gaucher disease: implications for long-term follow up of enzyme replacement therapy","volume":"344","author":"Cabrera-Salazar","year":"2004","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.gene.2013.03.044_bb0055","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1750-1172-7-12","article-title":"Gaucher disease and the synucleinopathies: refining the relationship","volume":"7","author":"Campbell","year":"2012","journal-title":"Orphanet J. Rare Dis."},{"key":"10.1016\/j.gene.2013.03.044_bb0125","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0009-8981(01)00798-7","article-title":"Gaucher and Niemann\u2013Pick diseases\u2014enzymatic diagnosis in dried blood spots on filter paper: retrospective diagnoses in newborn-screening cards","volume":"317","author":"Chamoles","year":"2002","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.gene.2013.03.044_bb0085","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S1357-2725(02)00309-6","article-title":"The angiotensin converting enzyme (ACE)","volume":"35","author":"Coates","year":"2003","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.gene.2013.03.044_bb0180","series-title":"Vascular Endothelium in Human Physiology and Pathophysiology","first-page":"302","article-title":"Endothelial dysfunction and regulation","author":"Corti","year":"2000"},{"key":"10.1016\/j.gene.2013.03.044_bb0090","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0076-6879(95)48020-X","article-title":"Peptidyl dipeptidase A: angiotensin I-converting enzyme","volume":"248","author":"Corvol","year":"1995","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.gene.2013.03.044_bb0035","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1023\/A:1012496514170","article-title":"Gaucher disease: understanding the molecular pathogenesis of sphingolipidoses","volume":"24","author":"Cox","year":"2001","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.gene.2013.03.044_bb0150","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/j.clinbiochem.2012.04.030","article-title":"Comparison between alpha-galactosidase A activity in blood samples collected on filter paper, leukocytes and plasma","volume":"45","author":"Daitx","year":"2012","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.gene.2013.03.044_bb0195","author":"R Development Core Team"},{"key":"10.1016\/j.gene.2013.03.044_bb0045","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1007\/s10545-006-0411-z","article-title":"Glucosylceramide transfer from lysosomes\u2014the missing link in molecular pathology of glucosylceramidase deficiency: a hypothesis based on existing data","volume":"29","author":"Elleder","year":"2006","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.gene.2013.03.044_bb0005","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1038\/nrm1423","article-title":"The cell biology of lysosomal storage disorders","volume":"5","author":"Futerman","year":"2004","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.gene.2013.03.044_bb0020","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/S0140-6736(08)61522-6","article-title":"Phenotype, diagnosis, and treatment of Gaucher's disease","volume":"372","author":"Grabowski","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.gene.2013.03.044_bb0175","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1002\/humu.20524","article-title":"Type 1 Gaucher disease: null and hypomorphic novel chitotriosidase mutations\u2014implications for diagnosis and therapeutic monitoring","volume":"28","author":"Grace","year":"2007","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.gene.2013.03.044_bb0165","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.micinf.2007.10.007","article-title":"Human chitotriosidase is expressed in the eye and lacrimal gland and has an antimicrobial spectrum different from lysozyme","volume":"10","author":"Hall","year":"2008","journal-title":"Microbes Infect."},{"key":"10.1016\/j.gene.2013.03.044_bb0135","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/clinchem\/30.6.901","article-title":"Automated kinetic determination of angiotensin-converting enzyme in serum","volume":"30","author":"Harjanne","year":"1984","journal-title":"Clin. Chem."},{"key":"10.1016\/j.gene.2013.03.044_bb9000","unstructured":"HGNC Database, HUGO Gene Nomenclature Committee (HGNC), EMBL Outstation - Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. Jan, 2013. URL: http:\/\/www.genenames.org."},{"key":"10.1016\/j.gene.2013.03.044_bb0070","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1172\/JCI117084","article-title":"Marked elevation of plasma chitotriosidase activity: a novel hallmark of Gaucher disease","volume":"93","author":"Hollak","year":"1994","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.gene.2013.03.044_bb0060","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1365-2141.2004.05351.x","article-title":"Gaucher disease: pathological mechanisms and modern management","volume":"129","author":"Jmoudiak","year":"2005","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.gene.2013.03.044_bb0160","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1177\/117727190700200023","article-title":"Human chitinases and chitinase-like proteins as indicators for inflammation and cancer","volume":"2","author":"Kzhyshkowska","year":"2007","journal-title":"Biomark. Insights"},{"key":"10.1016\/j.gene.2013.03.044_bb0095","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/s00018-009-0152-x","article-title":"Not just angiotensinases: new roles for the angiotensin-converting enzymes","volume":"67","author":"Lambert","year":"2010","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.gene.2013.03.044_bb0170","doi-asserted-by":"crossref","first-page":"S187","DOI":"10.1016\/S0248-8663(07)78880-X","article-title":"Current development and usefulness of biomarkers for Gaucher disease follow up","volume":"28","author":"Maire","year":"2007","journal-title":"Rev. Med. Interne"},{"key":"10.1016\/j.gene.2013.03.044_bb0110","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.1016\/S0149-2918(08)00366-4","article-title":"The role of current biomarkers in the management of lysosomal storage disorders","volume":"30","author":"Maire","year":"2008","journal-title":"Clin. Ther."},{"key":"10.1016\/j.gene.2013.03.044_bb0065","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.1007\/s00018-006-6269-2","article-title":"Chitotriosidase: the yin and yang","volume":"63","author":"Malaguarnera","year":"2006","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.gene.2013.03.044_bb0200","unstructured":"Matthew Morris, E., Fletcher, J. a, Thyfault, J.P., Scott Rector, R., in press. The role of angiotensin II in nonalcoholic steatohepatitis. Mol. Cell. Endocrinol. 1\u201312."},{"key":"10.1016\/j.gene.2013.03.044_bb0120","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1353\/dem.2007.0038","article-title":"What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research","volume":"44","author":"McDade","year":"2007","journal-title":"Demography"},{"key":"10.1016\/j.gene.2013.03.044_bb0030","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.cccn.2005.06.010","article-title":"Biochemical properties of beta-glucosidase in leukocytes from patients and obligated heterozygotes for Gaucher disease carriers","volume":"362","author":"Michelin","year":"2005","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.gene.2013.03.044_bb0205","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1152\/physiol.00041.2009","article-title":"Lysosomal storage disease: revealing lysosomal function and physiology","volume":"25","author":"Parkinson-Lawrence","year":"2010","journal-title":"Physiology (Bethesda)"},{"key":"10.1016\/j.gene.2013.03.044_bb0115","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/clinchem\/29.6.1093","article-title":"Direct spectrophotometric assay for angiotensin-converting enzyme in serum","volume":"29","author":"Ronca-Testoni","year":"1983","journal-title":"Clin. Chem."},{"key":"10.1016\/j.gene.2013.03.044_bb0105","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.clinbiochem.2011.05.016","article-title":"Biomarkers in Serbian patients with Gaucher disease","volume":"44","author":"Sumarac","year":"2011","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.gene.2013.03.044_bb0130","first-page":"23 - 23","article-title":"Evaluation of chitotriosidase in dried blood spot collected of filter paper: reference values in control subjects and patients with lysosomal storage diseases","volume":"61","author":"Uribe","year":"2009","journal-title":"Rev. Investig. Clin."},{"key":"10.1016\/j.gene.2013.03.044_bb0210","unstructured":"Uribe, A., Pacheco, N., submitted for publication. Chitotriosidase levels in dried blood spots: application of a microtechnique to the normal population and patients with lysosomal disorders. Clin. Biochem. 1\u201313."},{"key":"10.1016\/j.gene.2013.03.044_bb0015","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1365-2141.2004.05293.x","article-title":"Lysosomal storage disorders","volume":"128","author":"Vellodi","year":"2005","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.gene.2013.03.044_bb0080","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s10545-005-0585-9","article-title":"Evaluation of three biochemical markers in the monitoring of Gaucher disease","volume":"28","author":"Vellodi","year":"2005","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.gene.2013.03.044_bb0075","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.clinbiochem.2004.06.008","article-title":"Biochemical characterization of chitotriosidase enzyme: comparison between normal individuals and patients with Gaucher and with Niemann\u2013Pick diseases","volume":"37","author":"Wajner","year":"2004","journal-title":"Clin. Biochem."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111913002795?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111913002795?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T04:31:23Z","timestamp":1595565083000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111913002795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S0378111913002795"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2013.03.044","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}