{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:53:37Z","timestamp":1761663217001,"version":"3.37.3"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81230068","81001274","81202268","81102089"],"award-info":[{"award-number":["81230068","81001274","81202268","81102089"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"crossref","award":["BK2011773","BK2012842"],"award-info":[{"award-number":["BK2011773","BK2012842"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Key Program for Basic Research of Jiangsu Provincial Department of Education","award":["11KJB330002","12KJA330002"],"award-info":[{"award-number":["11KJB330002","12KJA330002"]}]},{"name":"Qing-Lan Project of Jiangsu Provincial Department of Education"},{"DOI":"10.13039\/501100012246","name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012246","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.gene.2013.11.087","type":"journal-article","created":{"date-parts":[[2013,12,8]],"date-time":"2013-12-08T13:45:30Z","timestamp":1386510330000},"page":"59-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Genetic variation rs10484761 on 6p21.1 derived from a genome-wide association study is associated with gastric cancer survival in a Chinese population"],"prefix":"10.1016","volume":"536","author":[{"given":"Meiyun","family":"Kang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojie","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haixia","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meilin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weida","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengdong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2013.11.087_bb0005","doi-asserted-by":"crossref","first-page":"6061","DOI":"10.3748\/wjg.15.6061","article-title":"Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer","volume":"15","author":"Alakus","year":"2009","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.gene.2013.11.087_bb0010","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1089\/gtmb.2012.0047","article-title":"GNAS1 (Galphas) gene T393C polymorphism and renal cell carcinoma risk in a North Indian population: a case\u2013control study","volume":"16","author":"Arjumand","year":"2012","journal-title":"Genet. Test. Mol. Biomarkers"},{"key":"10.1016\/j.gene.2013.11.087_bb0015","doi-asserted-by":"crossref","first-page":"3030","DOI":"10.1200\/JCO.2010.33.6313","article-title":"Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome","volume":"29","author":"Begnami","year":"2011","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.gene.2013.11.087_bb0020","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0002-9440(10)64549-X","article-title":"Genetic imbalances with impact on survival in head and neck cancer patients","volume":"157","author":"Bockmuhl","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.gene.2013.11.087_bb0025","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/978-1-60327-492-0_23","article-title":"Epidemiology of stomach cancer","volume":"472","author":"Brenner","year":"2009","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.gene.2013.11.087_bb0030","doi-asserted-by":"crossref","first-page":"5231","DOI":"10.1007\/s11033-010-0674-1","article-title":"An association between DNA repair gene polymorphisms and survival in patients with resected non-small cell lung cancer","volume":"38","author":"Butkiewicz","year":"2011","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.gene.2013.11.087_bb0035","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/nature02623","article-title":"Mapping complex disease loci in whole-genome association studies","volume":"429","author":"Carlson","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.gene.2013.11.087_bb0040","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s10549-007-9637-1","article-title":"XRCC1 Arg399Gln and RAD51 5\u2032UTR G135C polymorphisms and their outcome in tumor aggressiveness and survival of Portuguese breast cancer patients","volume":"109","author":"Costa","year":"2008","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.gene.2013.11.087_bb0045","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1038\/nature07631","article-title":"Progress and challenges in genome-wide association studies in humans","volume":"456","author":"Donnelly","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.gene.2013.11.087_bb0050","doi-asserted-by":"crossref","first-page":"207","DOI":"10.2478\/10004-1254-62-2011-2098","article-title":"Association between XRCC1 ARG399GLN and P53 ARG72PRO polymorphisms and the risk of gastric and colorectal cancer in Turkish population","volume":"62","author":"Engin","year":"2011","journal-title":"Arh. Hig. Rada. Toksikol."},{"key":"10.1016\/j.gene.2013.11.087_bb0055","doi-asserted-by":"crossref","first-page":"2893","DOI":"10.1002\/ijc.25516","article-title":"Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008","volume":"127","author":"Ferlay","year":"2010","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.gene.2013.11.087_bb0060","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/gcc.20136","article-title":"Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization","volume":"42","author":"Gorringe","year":"2005","journal-title":"Gene Chromosome Cancer"},{"key":"10.1016\/j.gene.2013.11.087_bb0065","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/ng2098","article-title":"A common genetic risk factor for colorectal and prostate cancer","volume":"39","author":"Haiman","year":"2007","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0070","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0140-6736(03)13975-X","article-title":"Gastric cancer","volume":"362","author":"Hohenberger","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.gene.2013.11.087_bb0075","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3322\/caac.20107","article-title":"Global cancer statistics","volume":"61","author":"Jemal","year":"2011","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.gene.2013.11.087_bb0080","doi-asserted-by":"crossref","first-page":"8646","DOI":"10.1073\/pnas.1205654109","article-title":"The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type","volume":"109","author":"Jendrzejewski","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.gene.2013.11.087_bb0085","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.ajhg.2012.09.009","article-title":"Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese","volume":"91","author":"Jin","year":"2012","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0090","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1136\/jmedgenet-2011-100586","article-title":"Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24","volume":"49","author":"Jones","year":"2012","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0095","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1086\/426833","article-title":"Long-range control of gene expression: emerging mechanisms and disruption in disease","volume":"76","author":"Kleinjan","year":"2005","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0100","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.1097\/MLG.0b013e318185793ds","article-title":"The GNAS1 T393C polymorphism predicts survival in patients with advanced squamous cell carcinoma of the larynx","volume":"118","author":"Lehnerdt","year":"2008","journal-title":"Laryngoscope"},{"key":"10.1016\/j.gene.2013.11.087_bb0105","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1136\/jmedgenet-2011-100063","article-title":"The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population","volume":"48","author":"Matsuse","year":"2011","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0110","article-title":"Genetic variants in the fibroblast growth factor pathway as potential markers of ovarian cancer risk, therapeutic response, and clinical outcome","author":"Meng","year":"2013","journal-title":"Clin. Chem"},{"key":"10.1016\/j.gene.2013.11.087_bb0115","doi-asserted-by":"crossref","first-page":"156","DOI":"10.4251\/wjgo.v4.i7.156","article-title":"Carcinoma of the stomach: a review of epidemiology, pathogenesis, molecular genetics and chemoprevention","volume":"4","author":"Nagini","year":"2012","journal-title":"World J. Gastrointest. Oncol."},{"key":"10.1016\/j.gene.2013.11.087_bb0120","first-page":"658","article-title":"Genomic alterations in primary gastric cancers analyzed by comparative genomic hybridization and clinicopathological factors","volume":"47","author":"Nakanishi","year":"2000","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.gene.2013.11.087_bb0125","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.3109\/0284186X.2012.754991","article-title":"The lymph node ratio as a prognostic factor for gastric cancer","volume":"52","author":"Nelen","year":"2013","journal-title":"Acta Oncol."},{"key":"10.1016\/j.gene.2013.11.087_bb0130","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s10549-006-9462-y","article-title":"The T393C polymorphism in the gene GNAS1 of G protein is associated with survival of patients with invasive breast carcinoma","volume":"105","author":"Otterbach","year":"2007","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.gene.2013.11.087_bb0135","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1056\/NEJMc1010310","article-title":"Genomewide association studies and assessment of risk of disease","volume":"363","author":"Pandey","year":"2010","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.gene.2013.11.087_bb0140","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/ng.403","article-title":"The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer","volume":"41","author":"Pomerantz","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0145","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/1097-0215(20000520)89:3<217::AID-IJC2>3.0.CO;2-6","article-title":"Amplification and over-expression of the AIB1 nuclear receptor co-activator gene in primary gastric cancers","volume":"89","author":"Sakakura","year":"2000","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.gene.2013.11.087_bb0150","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/ng2085","article-title":"A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21","volume":"39","author":"Tomlinson","year":"2007","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0155","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1002\/ijc.25740","article-title":"Genetic variant in PSCA predicts survival of diffuse-type gastric cancer in a Chinese population","volume":"129","author":"Wang","year":"2011","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.gene.2013.11.087_bb0160","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s11033-012-2093-y","article-title":"A functional polymorphism in XRCC1 is associated with glioma risk: evidence from a meta-analysis","volume":"40","author":"Wei","year":"2013","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.gene.2013.11.087_bb0165","doi-asserted-by":"crossref","first-page":"R101","DOI":"10.1093\/hmg\/ddi104","article-title":"Remote control of gene transcription","volume":"14","author":"West","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0175","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/gcc.10106","article-title":"Clinical implications of chromosomal abnormalities in gastric adenocarcinomas","volume":"35","author":"Wu","year":"2002","journal-title":"Gene Chromosome Cancer"},{"key":"10.1016\/j.gene.2013.11.087_bb0170","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/ng.849","article-title":"Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations","volume":"43","author":"Wu","year":"2011","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0180","first-page":"160","article-title":"Clinicopathological features and prognosis of young patients with gastric cancer","volume":"16","author":"Xu","year":"2013","journal-title":"Zhonghua Wei Chang Wai Ke Za Zhi"},{"key":"10.1016\/j.gene.2013.11.087_bb0185","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3748\/wjg.v12.i1.17","article-title":"Incidence and mortality of gastric cancer in China","volume":"12","author":"Yang","year":"2006","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.gene.2013.11.087_bb0190","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/ng2089","article-title":"Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24","volume":"39","author":"Zanke","year":"2007","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2013.11.087_bb0195","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s13277-012-0581-2","article-title":"X-ray repair cross-complementing group 1 Arg399Gln gene polymorphism and susceptibility to colorectal cancer: a meta-analysis","volume":"34","author":"Zeng","year":"2013","journal-title":"Tumour Biol."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111913016132?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111913016132?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T08:32:06Z","timestamp":1562142726000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111913016132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S0378111913016132"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2013.11.087","relation":{},"ISSN":["0378-1119"],"issn-type":[{"type":"print","value":"0378-1119"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic variation rs10484761 on 6p21.1 derived from a genome-wide association study is associated with gastric cancer survival in a Chinese population","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2013.11.087","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}