{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T15:40:49Z","timestamp":1762875649350},"reference-count":37,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Taif University Postgraduate & Research Affairs"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1016\/j.gene.2014.12.065","type":"journal-article","created":{"date-parts":[[2015,1,2]],"date-time":"2015-01-02T16:12:43Z","timestamp":1420215163000},"page":"215-219","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Vitamin D receptor gene polymorphisms and steroid receptor status among Saudi women with breast cancer"],"prefix":"10.1016","volume":"558","author":[{"given":"Dalal M.","family":"Nemenqani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rehab A.","family":"Karam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona G.","family":"Amer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer M.","family":"Abd El Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.gene.2014.12.065_bb0140","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/ijc.23904","article-title":"Plasma 25-hydroxyvitamin D premenopausal breast cancer risk in a German case\u2013control study","volume":"124","author":"Abbas","year":"2009","journal-title":"Int. J. Cancer"},{"issue":"3","key":"10.1016\/j.gene.2014.12.065_bb0130","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/aje\/kwr091","article-title":"Ultraviolet sunlight exposure during adolescence and adulthood and breast cancer risk: a population-based case\u2013control study among Ontario women","volume":"174","author":"Anderson","year":"2011","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.gene.2014.12.065_bb0200","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1359\/jbmr.1997.12.6.915","article-title":"A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women","volume":"12","author":"Arai","year":"1997","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.gene.2014.12.065_bb0075","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/bjc.1957.43","article-title":"Histological grading and prognosis","volume":"11","author":"Bloom","year":"1957","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.gene.2014.12.065_bb0165","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/emm.2003.72","article-title":"Vitamin D receptor gene polymorphisms in breast cancer","volume":"35","author":"Buyru","year":"2003","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.gene.2014.12.065_bb0180","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1158\/1055-9965.EPI-05-0283","article-title":"Associations between polymorphisms in the Vitamin D receptor and breast cancer risk","volume":"14","author":"Chen","year":"2005","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.gene.2014.12.065_bb0205","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1046\/j.1365-2265.2000.00909.x","article-title":"Consequences of vitamin D receptor gene polymorphisms for growth inhibition of cultured human peripheral blood mononuclear cells by 1,25-dihydroxyvitamin D3","volume":"52","author":"Colin","year":"2000","journal-title":"Clin. Endocrinol. (Oxf)"},{"key":"10.1016\/j.gene.2014.12.065_bb0080","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/(SICI)1097-0215(19991210)83:6<723::AID-IJC4>3.0.CO;2-3","article-title":"Association of A vitamin D receptor polymorphism with sporadic breast cancer development","volume":"83","author":"Curran","year":"1999","journal-title":"Int. J. Cancer"},{"issue":"1","key":"10.1016\/j.gene.2014.12.065_bb0105","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1582-4934.2005.tb00350.x","article-title":"Understanding breast cancer risk \u2014 where do we stand in 2005?","volume":"9","author":"Dumitrescu","year":"2005","journal-title":"J. Cell. Mol. Med."},{"issue":"7","key":"10.1016\/j.gene.2014.12.065_bb0010","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/1471-2407-7-222","article-title":"Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: the Saudi Arabia experience","volume":"5","author":"Elkum","year":"2007","journal-title":"BMC Cancer"},{"key":"10.1016\/j.gene.2014.12.065_bb0115","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1186\/1471-2407-14-788","article-title":"Obesity is a significant risk factor for breast cancer in Arab women","volume":"14","author":"Elkum","year":"2014","journal-title":"BMC Cancer"},{"issue":"707","key":"10.1016\/j.gene.2014.12.065_bb0120","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1136\/pgmj.60.707.589","article-title":"Exposure to sunlight and vitamin D deficiency in Saudi Arabian women","volume":"60","author":"Fonseca","year":"1984","journal-title":"Postgrad. Med. J."},{"issue":"2","key":"10.1016\/j.gene.2014.12.065_bb0055","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1007\/s13277-013-1176-2","article-title":"Polymorphisms in the vitamin D receptor gene and the lung cancer risk","volume":"35","author":"Fu","year":"2014","journal-title":"Tumour Biol."},{"key":"10.1016\/j.gene.2014.12.065_bb0015","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/0091-7435(90)90058-R","article-title":"Geographic variation in breast cancer mortality in the United States: a hypothesis involving exposure to solar radiation","volume":"19","author":"Garland","year":"1990","journal-title":"Prev. Med."},{"key":"10.1016\/j.gene.2014.12.065_bb0195","doi-asserted-by":"crossref","first-page":"5472","DOI":"10.1158\/1078-0432.CCR-04-0206","article-title":"Vitamin D receptor gene polymorphisms and breast cancer risk","volume":"10","author":"Guy","year":"2004","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.gene.2014.12.065_bb0035","doi-asserted-by":"crossref","first-page":"D820","DOI":"10.2741\/Hansen","article-title":"Vitamin D and cancer: effects of 1,25(OH)2 D3 and its analogs on growth control and tumorigenesis","volume":"6","author":"Hansen","year":"2001","journal-title":"Front. Biosci."},{"key":"10.1016\/j.gene.2014.12.065_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1023\/A:1016048900049","article-title":"Association of vitamin D receptor gene polymorphism with sporadic breast cancer in Taiwanese patients","volume":"74","author":"Hou","year":"2002","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.gene.2014.12.065_bb0185","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1023\/A:1008979417618","article-title":"Vitamin D receptor genotype and breast cancer in Latinas (United States)","volume":"11","author":"Ingles","year":"2000","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.gene.2014.12.065_bb0215","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1677\/joe.0.1410555","article-title":"Effects of a new synthetic vitamin D analogue, EB on the oestrogen-responsive growth of human breast cancer cells","volume":"141","author":"James","year":"1994","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.gene.2014.12.065_bb0090","series-title":"Histological and Histochemical Methods: Theory and Practice","author":"Kiernan","year":"1999"},{"key":"10.1016\/j.gene.2014.12.065_bb0030","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.mam.2008.08.005","article-title":"Geographic location and vitamin D synthesis","volume":"29","author":"Kimlin","year":"2008","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.gene.2014.12.065_bb0150","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1158\/1055-9965.EPI-06-0865","article-title":"Vitamin D and reduced risk of breast cancer: a population-based case\u2013control study","volume":"16","author":"Knight","year":"2007","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.gene.2014.12.065_bb0050","first-page":"3511","article-title":"The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature","volume":"29","author":"K\u00f6stner","year":"2009","journal-title":"Anticancer Res."},{"key":"10.1016\/j.gene.2014.12.065_bb0125","series-title":"Proceeding of Workshop on Prevention and Control of Micronutrient Deficiencies in the Arab Gulf Cooperation Council Countries","isbn-type":"print","author":"Kumosani","year":"1997","ISBN":"http:\/\/id.crossref.org\/isbn\/9285510477"},{"key":"10.1016\/j.gene.2014.12.065_bb0070","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1023\/A:1018778403001","article-title":"The loss of estrogen and progesterone receptor gene expression in human breast cancer","volume":"3","author":"Lapidus","year":"1998","journal-title":"J. Mammary Gland Biol. Neoplasia"},{"key":"10.1016\/j.gene.2014.12.065_bb0175","doi-asserted-by":"crossref","first-page":"R9","DOI":"10.1186\/bcr1642","article-title":"Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case\u2013control study","volume":"9","author":"McCullough","year":"2007","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.gene.2014.12.065_bb0045","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1006\/geno.1994.1424","article-title":"Mapping of the 12q12-q22 region with respect to tumor translocation breakpoints","volume":"22","author":"Pedeutour","year":"1994","journal-title":"Genomics"},{"issue":"8","key":"10.1016\/j.gene.2014.12.065_bb0095","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1093\/oxfordjournals.aje.a117079","article-title":"Reproductive risk factors in a prospective study of breast cancer: the Nurses' Health Study","volume":"139","author":"Rosner","year":"1994","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.gene.2014.12.065_bb0005","series-title":"Cancer Incidence and Survival Report Saudi Arabia. 2007","author":"Saudi National Cancer Registry","year":"2011"},{"issue":"7","key":"10.1016\/j.gene.2014.12.065_bb0060","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3109\/08820139.2013.822881","article-title":"Vitamin D receptor FokI, BsmI, ApaI, and TaqI polymorphisms and susceptibility to ovarian cancer: a meta-analysis","volume":"42","author":"Song","year":"2013","journal-title":"Immunol. Investig."},{"key":"10.1016\/j.gene.2014.12.065_bb0225","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1002\/(SICI)1097-4644(19991215)75:4<640::AID-JCB10>3.0.CO;2-8","article-title":"Regulation of estrogen receptor-alpha gene expression by 1,25-dihydroxyvitamin D in MCF-7 cells","volume":"75","author":"Stoica","year":"1999","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.gene.2014.12.065_bb0220","first-page":"3371","article-title":"1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells","volume":"6","author":"Swami","year":"2000","journal-title":"Clin. Cancer Res."},{"issue":"3","key":"10.1016\/j.gene.2014.12.065_bb0110","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1023\/B:JOMG.0000048770.90334.3b","article-title":"The genetic epidemiology of breast cancer genes","volume":"9","author":"Thompson","year":"2004","journal-title":"J. Mammary Gland Biol. Neoplasia"},{"key":"10.1016\/j.gene.2014.12.065_bb0085","doi-asserted-by":"crossref","first-page":"R84","DOI":"10.1186\/bcr1833","article-title":"Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case control study of Caucasian and African-American women","volume":"9","author":"Trabert","year":"2007","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.gene.2014.12.065_bb0210","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.gene.2004.05.014","article-title":"Genetics and biology of vitamin D receptor polymorphisms","volume":"338","author":"Uitterlinden","year":"2004","journal-title":"Gene"},{"key":"10.1016\/j.gene.2014.12.065_bb0025","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1210\/jcem-67-2-373","article-title":"Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin","volume":"67","author":"Webb","year":"1988","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.gene.2014.12.065_bb0020","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1111\/j.1745-7254.2007.00700.x","article-title":"Vitamin D and prevention of breast cancer","volume":"28","author":"Welsh","year":"2007","journal-title":"Acta Pharmacol. Sin."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111914014917?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111914014917?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T04:53:15Z","timestamp":1566190395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111914014917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["S0378111914014917"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2014.12.065","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2015,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vitamin D receptor gene polymorphisms and steroid receptor status among Saudi women with breast cancer","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2014.12.065","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}