{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:47:19Z","timestamp":1791424039261,"version":"4.3.3"},"reference-count":87,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.gene.2016.04.011","type":"journal-article","created":{"date-parts":[[2016,4,9]],"date-time":"2016-04-09T19:28:26Z","timestamp":1460230106000},"page":"136-147","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["High-resolution chromosome ideogram representation of recognized genes for bipolar disorder"],"prefix":"10.1016","volume":"586","author":[{"given":"Lindsay N.","family":"Douglas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austen B.","family":"McGuire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann M.","family":"Manzardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merlin G.","family":"Butler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2016.04.011_bb0005","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/sj.mp.4002012","article-title":"A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder","volume":"13","author":"Baum","year":"2008","journal-title":"Mol. Psychiatry"},{"issue":"5","key":"10.1016\/j.gene.2016.04.011_bb0010","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/mp.2008.16","article-title":"Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement","volume":"13","author":"Baum","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0015","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s10048-001-0129-x","article-title":"A mannosyltransferase gene at 11q23 is disrupted by a translocation breakpoint that co-segregates with bipolar affective disorder in a small family","volume":"4","author":"Baysal","year":"2002","journal-title":"Neurogenetics"},{"key":"10.1016\/j.gene.2016.04.011_bb0020","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/ajmg.b.20038","article-title":"Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression","volume":"123B","author":"Benedetti","year":"2003","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"issue":"2","key":"10.1016\/j.gene.2016.04.011_bb0025","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.neulet.2008.09.002","article-title":"A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder","volume":"445","author":"Benedetti","year":"2008","journal-title":"Neurosci. Lett."},{"issue":"2","key":"10.1016\/j.gene.2016.04.011_bb0030","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1001\/archpsyc.63.2.175","article-title":"Clinical course of children and adolescents with bipolar spectrum disorders","volume":"63","author":"Birmaher","year":"2006","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1","key":"10.1016\/j.gene.2016.04.011_bb0035","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF03033484","article-title":"Are some genetic risk factors common to schizophrenia, bipolar disorder and depression? Evidence from DISC1, GRIK4 and NRG1","volume":"11","author":"Blackwood","year":"2007","journal-title":"Neurotox. Res."},{"issue":"4","key":"10.1016\/j.gene.2016.04.011_bb0040","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/sj.mp.4001784","article-title":"Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility allele","volume":"11","author":"Blair","year":"2006","journal-title":"Mol. Psychiatry"},{"issue":"7145","key":"10.1016\/j.gene.2016.04.011_bb0045","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/nature05911","article-title":"Genomewide association study of 14,000 cases of seven common diseases and 3,000 shared controls","volume":"447","author":"Burton","year":"2007","journal-title":"Nature"},{"issue":"1-2","key":"10.1016\/j.gene.2016.04.011_bb0050","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jad.2011.04.018","article-title":"Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: evidence from the current studies","volume":"138","author":"Chen","year":"2012","journal-title":"J. Affect. Disord."},{"issue":"4","key":"10.1016\/j.gene.2016.04.011_bb0055","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.biopsych.2010.09.042","article-title":"Gene expression and genetic variation data implicate PCLO in bipolar disorder","volume":"69","author":"Choi","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0060","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/hmg\/ddm286","article-title":"Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5-prime region are associated with bipolar affective disorder","volume":"17","author":"Cichon","year":"2008","journal-title":"Hum. Mol. Genet."},{"issue":"5","key":"10.1016\/j.gene.2016.04.011_bb0065","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1176\/appi.ajp.2008.08091354","article-title":"Genomewide association studies: history, rationale, and prospects for psychiatric disorders","volume":"166","author":"Cichon","year":"2009","journal-title":"Am. J. Psychiatry"},{"issue":"3","key":"10.1016\/j.gene.2016.04.011_bb0070","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.ajhg.2011.01.017","article-title":"Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder","volume":"88","author":"Cichon","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0075","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/sj.mp.4001713","article-title":"Alternative transcripts and evidence of imprinting of GNAL on 18p11.2.","volume":"10","author":"Corradi","year":"2005","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0080","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1136\/jmg.36.8.585","article-title":"Genetics of bipolar disorder","volume":"36","author":"Craddock","year":"1999","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0085","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1136\/jmg.2005.030718","article-title":"The genetics of schizophrenia and bipolar disorder: dissecting psychosis","volume":"42","author":"Craddock","year":"2005","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0090","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1038\/sj.ejhg.5200803","article-title":"European combined analysis of the CTG18.1 and the ERDA1 CAG\/CTG repeats in bipolar disorder","volume":"10","author":"Del-Favero","year":"2002","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0095","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.biopsych.2006.01.019","article-title":"G72\/G30 in schizophrenia and bipolar disorder: review and meta-analysis","volume":"60","author":"Detera-Wadleigh","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0105","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.jad.2010.04.007","article-title":"A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample","volume":"126","author":"Djurovic","year":"2010","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.gene.2016.04.011_bb0110","doi-asserted-by":"crossref","first-page":"318483","DOI":"10.1155\/2014\/318483","article-title":"MTHFR gene polymorphism and age of onset of schizophrenia and bipolar disorder","volume":"2014","author":"El-Hadidy","year":"2014","journal-title":"Biomed. Res. Int."},{"issue":"18","key":"10.1016\/j.gene.2016.04.011_bb0115","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.1093\/hmg\/dds227","article-title":"Genetic and functional abnormalities of the melatonin biosynthesis pathway in patients with bipolar disorder","volume":"21","author":"Etain","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb9000","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/9780470751251.ch5","article-title":"Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism","volume":"289","author":"Fan","year":"2008","journal-title":"Novartis Found. Symp."},{"issue":"1","key":"10.1016\/j.gene.2016.04.011_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/YPG.0b013e3283351112","article-title":"Meta-analysis of the association between the monoamine oxidase-A gene and mood disorders","volume":"20","author":"Fan","year":"2010","journal-title":"Psychiatr. Genet."},{"issue":"9","key":"10.1016\/j.gene.2016.04.011_bb0125","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1038\/ng.209","article-title":"Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder","volume":"40","author":"Ferreira","year":"2008","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.gene.2016.04.011_bb0130","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/ajmg.b.30906","article-title":"Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case\u2013control study (BACCS)","volume":"150B","author":"Gaysina","year":"2009","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"issue":"5","key":"10.1016\/j.gene.2016.04.011_bb0135","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1001\/archpsyc.61.5.459","article-title":"Four-year prospective outcome and natural history of mania in children with a prepubertal and early adolescent bipolar disorder phenotype","volume":"61","author":"Geller","year":"2004","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1","key":"10.1016\/j.gene.2016.04.011_bb0140","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/sj.mp.4001190","article-title":"A novel CpG-associated brain-expressed candidate gene for chromosome 18q-linked bipolar disorder","volume":"8","author":"Goossens","year":"2003","journal-title":"Mol. Psychiatry"},{"issue":"2","key":"10.1016\/j.gene.2016.04.011_bb0145","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/sj.mp.4001764","article-title":"Identification of additional variants within the human dopamine transporter gene provides further evidence for an association with bipolar disorder in two independent samples","volume":"11","author":"Greenwood","year":"2006","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0150","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/tp.2012.30","article-title":"Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study","volume":"2","author":"Hammer","year":"2012","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0155","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/mp.2012.67","article-title":"Genome-wide significant associations in schizophrenia to ITIH3\/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the schizophrenia PGC","volume":"18","author":"Hamshere","year":"2013","journal-title":"Mol. Psychiatry"},{"issue":"10","key":"10.1016\/j.gene.2016.04.011_bb0160","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.biopsych.2005.02.019","article-title":"The breakpoint cluster region gene on chromosome 22q11 is associated with bipolar disorder","volume":"57","author":"Hashimoto","year":"2005","journal-title":"Biol. Psychiatry"},{"issue":"6","key":"10.1016\/j.gene.2016.04.011_bb0165","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1001\/archpsyc.59.6.521","article-title":"Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia","volume":"59","author":"Heckers","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"issue":"11","key":"10.1016\/j.gene.2016.04.011_bb0170","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ajp.157.11.1873","article-title":"Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire","volume":"157","author":"Hirschfeld","year":"2000","journal-title":"Am. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.gene.2016.04.011_bb0175","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4088\/JCP.v64n0111","article-title":"Screening for bipolar disorder in the community","volume":"64","author":"Hirschfeld","year":"2003","journal-title":"J. Clin. Psychiatry"},{"issue":"2","key":"10.1016\/j.gene.2016.04.011_bb0180","doi-asserted-by":"crossref","first-page":"161","DOI":"10.4088\/JCP.v64n0209","article-title":"Perceptions and impact of bipolar disorder: how far have we really come? Results of the National Depressive and Manic-Depressive Association 2000 survey of individuals with bipolar disorder","volume":"64","author":"Hirschfeld","year":"2003","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0185","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1086\/425586","article-title":"Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder","volume":"75","author":"Hodgkinson","year":"2004","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0195","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/ng1235","article-title":"Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder","volume":"35","author":"Kakiuchi","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0200","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3389\/fpsyt.2015.00105","article-title":"Toward a deeper understanding of the genetics of bipolar disorder","volume":"6","author":"Kerner","year":"2015","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0205","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3389\/fpsyt.2013.00154","article-title":"Rare genomic variants link bipolar disorder with anxiety disorders to CREB-regulated intracellular signaling pathways","volume":"4","author":"Kerner","year":"2013","journal-title":"Front. Psychiatry"},{"issue":"1-2","key":"10.1016\/j.gene.2016.04.011_bb0210","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.psychres.2010.06.003","article-title":"Serotonin 1A receptor gene, schizophrenia and bipolar disorder: an association study and meta-analysis","volume":"185","author":"Kishi","year":"2011","journal-title":"Psychiatry Res."},{"issue":"6","key":"10.1016\/j.gene.2016.04.011_bb0220","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/j.ajhg.2009.11.003","article-title":"A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression","volume":"85","author":"Knight","year":"2009","journal-title":"Am. J. Hum. Genet."},{"issue":"1","key":"10.1016\/j.gene.2016.04.011_bb0225","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.psy.0000151489.36347.18","article-title":"Psychiatric and medical comorbidities of bipolar disorder","volume":"67","author":"Krishnan","year":"2005","journal-title":"Psychosom. Med."},{"issue":"2","key":"10.1016\/j.gene.2016.04.011_bb0230","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/ajmg.b.30887","article-title":"Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms","volume":"150B","author":"Le-Niculescu","year":"2009","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0235","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.biopsych.2005.01.030","article-title":"The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: a meta-analysis","volume":"57","author":"L\u00f3pez Le\u00f3n","year":"2005","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.gene.2016.04.011_bb0240","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/01.chi.0000242240.69678.c4","article-title":"Practice parameter for the assessment and treatment of children and adolescents with bipolar disorder","volume":"46","author":"McClellan","year":"2007","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0245","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1176\/appi.ajp.158.3.420","article-title":"Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder","volume":"158","author":"McElroy","year":"2001","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0250","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/sj.mp.4001759","article-title":"Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3.","volume":"11","author":"McQuillin","year":"2006","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0255","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/bdi.12063","article-title":"C9ORF72 expansion in a family with bipolar disorder","volume":"15","author":"Meisler","year":"2013","journal-title":"Bipolar Disord."},{"issue":"3","key":"10.1016\/j.gene.2016.04.011_bb0260","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archgenpsychiatry.2011.12","article-title":"Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative","volume":"68","author":"Merikangas","year":"2011","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0265","doi-asserted-by":"crossref","first-page":"3339","DOI":"10.1038\/ncomms4339","article-title":"Genome-wide association study reveals two new risk loci for bipolar disorder","volume":"5","author":"M\u00fchleisen","year":"2014","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.gene.2016.04.011_bb0275","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1002\/ajmg.b.31023","article-title":"Support of association between BRD1 and both schizophrenia and bipolar affective disorder","volume":"153B","author":"Nyegaard","year":"2010","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0280","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/sj.mp.4001133","article-title":"Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case\u2013control samples and the NIMH Genetics Initiative bipolar pedigrees","volume":"7","author":"Ohtsuki","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0285","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1038\/mp.2008.122","article-title":"Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort","volume":"14","author":"Ollila","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0290","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.neubiorev.2015.04.022","article-title":"CACNA1C Rs1006737 genotype and bipolar disorder: focus on intermediate phenotypes and cardiovascular comorbidity","volume":"55","author":"Ou","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.gene.2016.04.011_bb0295","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.schres.2008.04.013","article-title":"Analysis of protocadherin alpha gene enhancer polymorphism in bipolar disorder and schizophrenia","volume":"102","author":"Pedrosa","year":"2008","journal-title":"Schizophr. Res."},{"issue":"9","key":"10.1016\/j.gene.2016.04.011_bb0300","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1038\/mp.2008.24","article-title":"Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder","volume":"14","author":"Pickard","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0305","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1034\/j.1399-5618.2000.020103.x","article-title":"Searching high and low: a review of the genetics of bipolar disorder","volume":"2","author":"Potash","year":"2000","journal-title":"Bipolar Disord."},{"issue":"3","key":"10.1016\/j.gene.2016.04.011_bb0310","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1097\/YPG.0b013e32832a4f69","article-title":"An association study of the neuregulin 1 gene, bipolar affective disorder and psychosis","volume":"19","author":"Prata","year":"2009","journal-title":"Psychiatr. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0315","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/nature08185","article-title":"International Schizophrenia Consortium: common polygenic variation contributes to risk of schizophrenia and bipolar disorder","volume":"460","author":"Purcell","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.gene.2016.04.011_bb0320","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1002\/1096-8628(20000612)96:3<317::AID-AJMG17>3.0.CO;2-R","article-title":"Analysis of the pseudoautosomal X-linked gene SYBL1 in bipolar affective disorder: description of a new candidate allele for psychiatric disorders","volume":"96B","author":"Saito","year":"2000","journal-title":"Am. J. Med. Genet."},{"issue":"4","key":"10.1016\/j.gene.2016.04.011_bb0325","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1002\/ajmg.b.31057","article-title":"Functional variants of TSPAN8 are associated with bipolar disorder and schizophrenia","volume":"153B","author":"Scholz","year":"2010","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"issue":"9","key":"10.1016\/j.gene.2016.04.011_bb0330","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1038\/mp.2008.20","article-title":"Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania","volume":"19","author":"Shaltiel","year":"2008","journal-title":"Mol. Psychiatry"},{"issue":"3","key":"10.1016\/j.gene.2016.04.011_bb0335","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/YPG.0b013e3282fa184b","article-title":"PDLIM5 and susceptibility to bipolar disorder: a family-based association study and meta-analysis","volume":"18","author":"Shi","year":"2008","journal-title":"Psychiatr. Genet."},{"issue":"11","key":"10.1016\/j.gene.2016.04.011_bb0340","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s11920-014-0493-5","article-title":"New developments in the genetics of bipolar disorder","volume":"16","author":"Shinozaki","year":"2014","journal-title":"Curr. Psychiatry Rep."},{"issue":"6","key":"10.1016\/j.gene.2016.04.011_bb0345","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/sj.mp.4001460","article-title":"Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder","volume":"9","author":"Sj\u00f8holt","year":"2004","journal-title":"Mol. Psychiatry"},{"issue":"6","key":"10.1016\/j.gene.2016.04.011_bb0350","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/sj.mp.4002151","article-title":"Whole-genome association study of bipolar disorder","volume":"13","author":"Sklar","year":"2008","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0355","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1038\/ng.943","article-title":"Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4","volume":"43","author":"Sklar","year":"2011","journal-title":"Nat. Genet."},{"issue":"8","key":"10.1016\/j.gene.2016.04.011_bb0360","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/mp.2009.43","article-title":"Genome-wide association study of bipolar disorder in European American and African American individuals","volume":"14","author":"Smith","year":"2009","journal-title":"Mol. Psychiatry"},{"issue":"1","key":"10.1016\/j.gene.2016.04.011_bb0365","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ajmg.c.20013","article-title":"Family, twin, and adoption studies of bipolar disorder","volume":"123C","author":"Smoller","year":"2003","journal-title":"Am. J. Med. Genet. C: Semin. Med. Genet."},{"key":"10.1016\/j.gene.2016.04.011_bb0370","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1038\/npp.2009.230","article-title":"Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder","volume":"35","author":"Soria","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.gene.2016.04.011_bb0375","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/mp.2009.86","article-title":"Replication of GWAS of bipolar disorder: association of SNPs near CDH7 with bipolar disorder and visual processing","volume":"15","author":"Soronen","year":"2010","journal-title":"Mol. Psychiatry"},{"issue":"3","key":"10.1016\/j.gene.2016.04.011_bb0380","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1002\/ajmg.b.31164","article-title":"Association of ANK3 with bipolar disorder confirmed in East Asia","volume":"156B","author":"Takata","year":"2011","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"issue":"7","key":"10.1016\/j.gene.2016.04.011_bb0385","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1002\/ajmg.b.31098","article-title":"Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case\u2013control sample","volume":"153B","author":"Tesli","year":"2010","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"issue":"5","key":"10.1016\/j.gene.2016.04.011_bb0390","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/sj.mp.4001593","article-title":"Sex-specific association between bipolar affective disorder in women and GPR50, and X-linked orphan G protein-coupled receptor","volume":"10","author":"Thomson","year":"2005","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0395","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1073\/pnas.0409665102","article-title":"In psychosis, cortical interneurons overexpress DNA-methyltransferase 1","volume":"102","author":"Veldic","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.gene.2016.04.011_bb0400","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/mp.2010.36","article-title":"Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder","volume":"16","author":"Williams","year":"2011","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0405","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2350-15-2","article-title":"Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1","volume":"15","author":"Xu","year":"2014","journal-title":"BMC Med. Genet."},{"issue":"10","key":"10.1016\/j.gene.2016.04.011_bb0410","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1007\/s00702-009-0260-7","article-title":"The Val\/Met functional polymorphism in COMT confers susceptibility to bipolar disorder: evidence from an association study and a meta-analysis","volume":"116","author":"Zhang","year":"2009","journal-title":"J. Neural Transm."},{"issue":"4","key":"10.1016\/j.gene.2016.04.011_bb0415","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3109\/08039488.2011.555564","article-title":"Meta-analysis of ACE gene I\/D polymorphism and bipolar disorder susceptibility","volume":"65","author":"Zou","year":"2011","journal-title":"Nord. J. Psychiatry"},{"key":"10.1016\/j.gene.2016.04.011_bb0420","author":"Depression and Bipolar Support Alliance"},{"key":"10.1016\/j.gene.2016.04.011_bb0425","author":"GeneCards"},{"key":"10.1016\/j.gene.2016.04.011_bb0430","author":"Juvenile Bipolar Research Foundation"},{"key":"10.1016\/j.gene.2016.04.011_bb0435","author":"National Center for Biotechnology Information"},{"key":"10.1016\/j.gene.2016.04.011_bb0440","author":"National Institute of Mental Health"},{"key":"10.1016\/j.gene.2016.04.011_bb0445","author":"Online Mendelian Inheritance in Man (OMIM)"},{"key":"10.1016\/j.gene.2016.04.011_bb0450","author":"PubMed."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111916302591?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111916302591?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T16:14:43Z","timestamp":1718468083000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111916302591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":87,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0378111916302591"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2016.04.011","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-resolution chromosome ideogram representation of recognized genes for bipolar disorder","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2016.04.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}