{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T05:33:22Z","timestamp":1779341602385,"version":"3.51.4"},"reference-count":42,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2014\/14230-0"],"award-info":[{"award-number":["2014\/14230-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2015\/05381-8"],"award-info":[{"award-number":["2015\/05381-8"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPq","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006303","name":"AFIP","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006303","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.gene.2016.10.007","type":"journal-article","created":{"date-parts":[[2016,10,9]],"date-time":"2016-10-09T18:10:08Z","timestamp":1476036608000},"page":"207-211","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Differential expression of microRNAs from miR-17 family in the cerebellum of mucopolysaccharidosis type I mice"],"prefix":"10.1016","volume":"595","author":[{"given":"Vanessa Gon\u00e7alves","family":"Pereira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matheus Trov\u00e3o","family":"Queiroz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0947-5312","authenticated-orcid":false,"given":"V\u00e2nia","family":"D'Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.gene.2016.10.007_bb0005","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10048-008-0133-5","article-title":"Heterogeneous dysregulation of microRNAs across the autism spectrum","volume":"9","author":"Abu-Elneel","year":"2008","journal-title":"Neurogenetics"},{"issue":"2","key":"10.1016\/j.gene.2016.10.007_bb0010","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejpn.2013.11.014","article-title":"Mucopolysaccharidoses type I and II: new neuroimaging findings in the cerebellum","volume":"18","author":"Alqahtani","year":"2014","journal-title":"Eur. J. Paediatr. Neurol."},{"issue":"3","key":"10.1016\/j.gene.2016.10.007_bb0015","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1007\/s12035-012-8270-0","article-title":"Integration of microRNA databases to study microRNAs associated with multiple sclerosis","volume":"45","author":"Angerstein","year":"2012","journal-title":"Mol. Neurobiol."},{"issue":"7209","key":"10.1016\/j.gene.2016.10.007_bb0020","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/nature07242","article-title":"The impact of microRNAs on protein output","volume":"455","author":"Baek","year":"2008","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.gene.2016.10.007_bb0025","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: target recognition and regulatory functions","volume":"136","author":"Bartel","year":"2009","journal-title":"Cell"},{"issue":"48","key":"10.1016\/j.gene.2016.10.007_bb0030","doi-asserted-by":"crossref","first-page":"37657","DOI":"10.1074\/jbc.M007380200","article-title":"Lysosomal neuraminidase. Catalytic activation in insect cells is controlled by the protective protein\/cathepsin A","volume":"275","author":"Bonten","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.gene.2016.10.007_bb0035","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1007\/s00018-013-1538-3","article-title":"Lysosomal multienzyme complex: pros and cons of working together","volume":"71","author":"Bonten","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"issue":"4","key":"10.1016\/j.gene.2016.10.007_bb0040","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1093\/hmg\/6.4.503","article-title":"Murine mucopolysaccharidosis type I: targeted disruption of the murine alpha-l-iduronidase gene","volume":"6","author":"Clarke","year":"1997","journal-title":"Hum. Mol. Genet."},{"issue":"5","key":"10.1016\/j.gene.2016.10.007_bb0045","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1111\/j.1471-4159.1978.tb12388.x","article-title":"Neurochemistry of the mucopolysaccharidoses: brain lipids and lysosomal enzymes in patients with four types of mucopolysaccharidosis and in normal controls","volume":"30","author":"Constantopoulos","year":"1978","journal-title":"J. Neurochem."},{"issue":"6","key":"10.1016\/j.gene.2016.10.007_bb0050","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1111\/j.1471-4159.1980.tb11220.x","article-title":"Mucopolysaccharidosis types IH, IS, II, and IIIA: glycosaminoglycans and lipids of isolated brain cells and other fractions from autopsied tissues","volume":"34","author":"Constantopoulos","year":"1980","journal-title":"J. Neurochem."},{"issue":"3","key":"10.1016\/j.gene.2016.10.007_bb0055","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.molcel.2009.09.028","article-title":"Hierarchical rules for Argonaute loading in Drosophila","volume":"36","author":"Czech","year":"2009","journal-title":"Mol. Cell"},{"issue":"17","key":"10.1016\/j.gene.2016.10.007_bb0060","doi-asserted-by":"crossref","first-page":"4322","DOI":"10.1523\/JNEUROSCI.4815-07.2008","article-title":"Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus","volume":"28","author":"Davis","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.gene.2016.10.007_bb0065","doi-asserted-by":"crossref","first-page":"5840","DOI":"10.1038\/ncomms6840","article-title":"A non-conserved miRNA regulates lysosomal function and impacts on a human lysosomal storage disorder","volume":"5","author":"Frankel","year":"2014","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.gene.2016.10.007_bb0070","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1261\/rna.1972910","article-title":"Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway","volume":"16","author":"Ghildiyal","year":"2010","journal-title":"RNA"},{"issue":"6","key":"10.1016\/j.gene.2016.10.007_bb0075","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1016\/j.celrep.2014.05.029","article-title":"MicroRNAs establish robustness and adaptability of a critical gene network to regulate progenitor fate decisions during cortical neurogenesis","volume":"7","author":"Ghosh","year":"2014","journal-title":"Cell Rep."},{"issue":"2","key":"10.1016\/j.gene.2016.10.007_bb0080","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.ymgme.2013.12.003","article-title":"Neuroinflammation and alpha-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction","volume":"111","author":"Ginns","year":"2013","journal-title":"Mol. Genet. Metab."},{"issue":"20","key":"10.1016\/j.gene.2016.10.007_bb0085","doi-asserted-by":"crossref","first-page":"3959","DOI":"10.1093\/hmg\/ddq311","article-title":"Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration","volume":"19","author":"Hebert","year":"2010","journal-title":"Hum. Mol. Genet."},{"issue":"9","key":"10.1016\/j.gene.2016.10.007_bb0090","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1007\/s11064-011-0400-y","article-title":"Lipid composition of whole brain and cerebellum in Hurler syndrome (MPS IH) mice","volume":"36","author":"Heinecke","year":"2011","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.gene.2016.10.007_bb0095","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1186\/1471-2164-10-413","article-title":"Sequence features associated with microRNA strand selection in humans and flies","volume":"10","author":"Hu","year":"2009","journal-title":"BMC Genomics"},{"issue":"Pt 4","key":"10.1016\/j.gene.2016.10.007_bb0100","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1242\/jcs.059659","article-title":"RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells","volume":"123","author":"Kawase-Koga","year":"2010","journal-title":"J. Cell Sci."},{"issue":"10","key":"10.1016\/j.gene.2016.10.007_bb0105","doi-asserted-by":"crossref","first-page":"e7440","DOI":"10.1371\/journal.pone.0007440","article-title":"Multiple sclerosis: microRNA expression profiles accurately differentiate patients with relapsing-remitting disease from healthy controls","volume":"4","author":"Keller","year":"2009","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.gene.2016.10.007_bb0110","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.expneurol.2011.11.010","article-title":"MiR-106b impairs cholesterol efflux and increases Abeta levels by repressing ABCA1 expression","volume":"235","author":"Kim","year":"2012","journal-title":"Exp. Neurol."},{"issue":"1","key":"10.1016\/j.gene.2016.10.007_bb0115","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.gene.2013.06.002","article-title":"Alterations of membrane lipids and in gene expression of ganglioside metabolism in different brain structures in a mouse model of mucopolysaccharidosis type I (MPS I)","volume":"527","author":"Kreutz","year":"2013","journal-title":"Gene"},{"key":"10.1016\/j.gene.2016.10.007_bb0120","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.lfs.2016.01.044","article-title":"MiR-20a and miR-20b negatively regulate autophagy by targeting RB1CC1\/FIP200 in breast cancer cells","volume":"147","author":"Li","year":"2016","journal-title":"Life Sci."},{"issue":"5","key":"10.1016\/j.gene.2016.10.007_bb0125","doi-asserted-by":"crossref","first-page":"719","DOI":"10.4161\/auto.19469","article-title":"Autophagy in lysosomal storage disorders","volume":"8","author":"Lieberman","year":"2012","journal-title":"Autophagy"},{"issue":"4","key":"10.1016\/j.gene.2016.10.007_bb0130","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/cne.20355","article-title":"Differential subcellular localization of cholesterol, gangliosides, and glycosaminoglycans in murine models of mucopolysaccharide storage disorders","volume":"480","author":"McGlynn","year":"2004","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.gene.2016.10.007_bb0135","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.neuroscience.2012.08.009","article-title":"Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis","volume":"223","author":"McLoughlin","year":"2012","journal-title":"Neuroscience"},{"issue":"4","key":"10.1016\/j.gene.2016.10.007_bb0140","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1042\/BST20140142","article-title":"Regulation of miRNA strand selection: follow the leader?","volume":"42","author":"Meijer","year":"2014","journal-title":"Biochem. Soc. Trans."},{"issue":"23","key":"10.1016\/j.gene.2016.10.007_bb0145","doi-asserted-by":"crossref","first-page":"7068","DOI":"10.1158\/0008-5472.CAN-13-0927","article-title":"Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression","volume":"73","author":"Murphy","year":"2013","journal-title":"Cancer Res."},{"key":"10.1016\/j.gene.2016.10.007_bb0150","series-title":"The Metabolic and Molecular Bases of Inherited Disease","first-page":"3421","article-title":"The mucopolysaccharidoses","author":"Neufeld","year":"2001"},{"issue":"4","key":"10.1016\/j.gene.2016.10.007_bb0155","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1073\/pnas.252784899","article-title":"Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB","volume":"100","author":"Ohmi","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"3","key":"10.1016\/j.gene.2016.10.007_bb0160","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.molcel.2009.09.027","article-title":"Distinct mechanisms for microRNA strand selection by Drosophila Argonautes","volume":"36","author":"Okamura","year":"2009","journal-title":"Mol. Cell"},{"key":"10.1016\/j.gene.2016.10.007_bb0165","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/978-3-319-22671-2_6","article-title":"microRNAs and neurodegenerative diseases","volume":"888","author":"Qiu","year":"2015","journal-title":"Adv. Exp. Med. Biol."},{"issue":"5","key":"10.1016\/j.gene.2016.10.007_bb0170","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1399-0004.1998.tb02745.x","article-title":"Murine MPS I: insights into the pathogenesis of Hurler syndrome","volume":"53","author":"Russell","year":"1998","journal-title":"Clin. Genet."},{"issue":"4","key":"10.1016\/j.gene.2016.10.007_bb0175","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/gm144","article-title":"Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines","volume":"2","author":"Sarachana","year":"2010","journal-title":"Genome Med."},{"issue":"10","key":"10.1016\/j.gene.2016.10.007_bb0180","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1080\/15476286.2014.996085","article-title":"Identification of miRNAs that modulate glucocerebrosidase activity in Gaucher disease cells","volume":"11","author":"Siebert","year":"2014","journal-title":"RNA Biol."},{"issue":"4","key":"10.1016\/j.gene.2016.10.007_bb0185","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1007\/s12311-008-0083-3","article-title":"Cerebellar disorders in childhood: cognitive problems","volume":"7","author":"Steinlin","year":"2008","journal-title":"Cerebellum"},{"issue":"6","key":"10.1016\/j.gene.2016.10.007_bb0190","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1093\/emboj\/17.6.1588","article-title":"Transport of human lysosomal neuraminidase to mature lysosomes requires protective protein\/cathepsin A","volume":"17","author":"van der Spoel","year":"1998","journal-title":"EMBO J."},{"issue":"14","key":"10.1016\/j.gene.2016.10.007_bb0195","doi-asserted-by":"crossref","first-page":"10035","DOI":"10.1074\/jbc.275.14.10035","article-title":"Processing of lysosomal beta-galactosidase. The C-terminal precursor fragment is an essential domain of the mature enzyme","volume":"275","author":"van der Spoel","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.gene.2016.10.007_bb0200","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.bbamcr.2008.11.014","article-title":"Secondary lipid accumulation in lysosomal disease","volume":"1793","author":"Walkley","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.gene.2016.10.007_bb0205","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3174\/ajnr.A2832","article-title":"Brain and spinal MR imaging findings in mucopolysaccharidoses: a review","volume":"34","author":"Zafeiriou","year":"2013","journal-title":"AJNR Am. J. Neuroradiol."},{"issue":"7","key":"10.1016\/j.gene.2016.10.007_bb0210","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1242\/bio.20146734","article-title":"Role of the miR-17 approximately 92 cluster family in cerebellar and medulloblastoma development","volume":"3","author":"Zindy","year":"2014","journal-title":"Biol. Open"}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111916308022?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111916308022?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T16:22:26Z","timestamp":1536337346000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111916308022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0378111916308022"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2016.10.007","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential expression of microRNAs from miR-17 family in the cerebellum of mucopolysaccharidosis type I mice","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2016.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}