{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:18:36Z","timestamp":1790777916057,"version":"4.1.0"},"reference-count":15,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.gene.2017.04.024","type":"journal-article","created":{"date-parts":[[2017,4,19]],"date-time":"2017-04-19T00:32:35Z","timestamp":1492561955000},"page":"67-71","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"special_numbering":"C","title":["The impact of exposure to environmental contaminant on hepatocellular lipid metabolism"],"prefix":"10.1016","volume":"622","author":[{"given":"Zongguang","family":"Hui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rujiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2017.04.024_bb0005","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1017\/S0007114514002517","article-title":"Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat\/high-cholesterol diets?","volume":"112","author":"C\u00f4t\u00e9","year":"2014","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.gene.2017.04.024_bb0010","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1177\/0192623314558463","article-title":"Perfluorooctanoic acid (PFOA)-induced liver lesions in two strains of mice following developmental exposures: PPAR\u03b1 is not required","volume":"43","author":"Filgo","year":"2015","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.gene.2017.04.024_bb0015","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1111\/liv.13158","article-title":"Effects of liver transplantation on endocrine function: a systematic review","volume":"36","author":"Gariani","year":"2016","journal-title":"Liver Int."},{"key":"10.1016\/j.gene.2017.04.024_bb0020","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.chemosphere.2013.10.005","article-title":"The association between PFOA, PFOS and serum lipid levels in adolescents","volume":"98","author":"Geiger","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.gene.2017.04.024_bb0025","first-page":"4440","article-title":"Characterization of acetaminophen-induced cytotoxicity in target tissues","volume":"8","author":"Guo","year":"2016","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.gene.2017.04.024_bb0030","first-page":"8740-3874","article-title":"Perfluoroalkylation of unactivated alkenes with acid anhydrides as the perfluoroalkyl source","volume":"55","author":"Kawamura","year":"2016","journal-title":"Angew. Chem. Int. Ed. Eng."},{"key":"10.1016\/j.gene.2017.04.024_bb0035","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1097\/MPA.0000000000000555","article-title":"Characterization of insulin-Immunoreactive cells and endocrine cells within the duct system of the adult human pancreas","volume":"45","author":"Li","year":"2016","journal-title":"Pancreas"},{"key":"10.1016\/j.gene.2017.04.024_bb0040","doi-asserted-by":"crossref","first-page":"8913","DOI":"10.1073\/pnas.1323785111","article-title":"TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content","volume":"111","author":"Mahdessian","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.gene.2017.04.024_bb0045","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.cca.2016.07.003","article-title":"Association between lipoprotein(a) and nonalcoholic fatty liver disease among Korean adults","volume":"461","author":"Nam","year":"2016","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.gene.2017.04.024_bb0050","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/hep.28941","article-title":"Prevention of hepatic fibrosis with liver microsomal triglyceride transfer protein deletion in liver fatty acid binding protein null mice","volume":"65","author":"Newberry","year":"2017","journal-title":"Hepatology."},{"key":"10.1016\/j.gene.2017.04.024_bb0055","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.reprotox.2009.02.001","article-title":"Perfluoroalkyl chemicals and human fetal development: an epidemiologic review with clinical and toxicological perspectives","volume":"27","author":"Olsen","year":"2009","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.gene.2017.04.024_bb0060","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.rvsc.2016.04.007","article-title":"Obesity-driven prepartal hepatic lipid accumulation in dairy cows is associated with increased CD36 and SREBP-1 expression","volume":"107","author":"Prodanovi\u0107","year":"2016","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.gene.2017.04.024_bb0065","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1177\/0192623314551841","article-title":"Hepatic mitochondrial alteration in CD-1 mice associated with prenatal exposures to low doses of perfluorooctanoic acid (PFOA)","volume":"43","author":"Quist","year":"2015","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.gene.2017.04.024_bb0070","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s40265-014-0339-9","article-title":"Alipogene tiparvovec: a review of its use in adults with familial lipoprotein lipase deficiency","volume":"75","author":"Scott","year":"2015","journal-title":"Drugs"},{"key":"10.1016\/j.gene.2017.04.024_bb0075","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.mce.2011.01.009","article-title":"Perfluorooctanoic acid-induced inhibition of placental prolactin-family hormone and fetal growth retardation in mice","volume":"337","author":"Suh","year":"2011","journal-title":"Mol. Cell. Endocrinol."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111917302767?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111917302767?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,2]],"date-time":"2018-09-02T11:59:39Z","timestamp":1535889579000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111917302767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":15,"alternative-id":["S0378111917302767"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2017.04.024","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The impact of exposure to environmental contaminant on hepatocellular lipid metabolism","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2017.04.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}