{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T15:31:55Z","timestamp":1759073515943,"version":"3.40.5"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.gene.2017.07.005","type":"journal-article","created":{"date-parts":[[2017,7,8]],"date-time":"2017-07-08T12:16:57Z","timestamp":1499516217000},"page":"8-15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs"],"prefix":"10.1016","volume":"628","author":[{"given":"Aur\u00e9lie","family":"Delacr\u00e9taz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adna","family":"Zdralovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederik","family":"Vandenberghe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuria","family":"Saigi-Morgui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana\u00efs","family":"Glatard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Quteineh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Gholam-Rezaee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wassim","family":"Raffoul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee Ann","family":"Applegate","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paris","family":"Jafari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7991-466X","authenticated-orcid":false,"given":"Franziska","family":"Gamma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"von Gunten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Conus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin B.","family":"Eap","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.gene.2017.07.005_bb0005","doi-asserted-by":"crossref","first-page":"5032","DOI":"10.1128\/MCB.14.8.5032","article-title":"Regulation of c-jun expression during hypoxic and low-glucose stress","volume":"14","author":"Ausserer","year":"1994","journal-title":"Mol. Cell. Biol."},{"issue":"1","key":"10.1016\/j.gene.2017.07.005_bb0010","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/clpt.2011.97","article-title":"Mechanisms and genetics of antipsychotic-associated weight gain","volume":"90","author":"Balt","year":"2011","journal-title":"Clin. Pharmacol. Ther."},{"issue":"7","key":"10.1016\/j.gene.2017.07.005_bb0015","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.2337\/diabetes.49.7.1142","article-title":"Activating transcription factor-2 is a positive regulator in CaM kinase IV-induced human insulin gene expression","volume":"49","author":"Ban","year":"2000","journal-title":"Diabetes"},{"issue":"9","key":"10.1016\/j.gene.2017.07.005_bb0020","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1101\/gr.137323.112","article-title":"Annotation of functional variation in personal genomes using RegulomeDB","volume":"22","author":"Boyle","year":"2012","journal-title":"Genome Res."},{"year":"1984","series-title":"Classification and Regression Trees. Wadsworth B, CA","author":"Breiman","key":"10.1016\/j.gene.2017.07.005_bb0025"},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0030","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S0895-4356(02)00588-7","article-title":"A retrospective cohort study of diabetes mellitus and antipsychotic treatment in the United States","volume":"56","author":"Buse","year":"2003","journal-title":"J. Clin. Epidemiol."},{"issue":"171","key":"10.1016\/j.gene.2017.07.005_bb0035","first-page":"1994","article-title":"Follow-up of the metabolic syndrome induced by atypical antipsychotics: recommendations and pharmacogenetics perspectives","volume":"4","author":"Choong","year":"2008","journal-title":"Rev. Med. Suisse"},{"issue":"10","key":"10.1016\/j.gene.2017.07.005_bb0040","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1001\/jamapsychiatry.2013.187","article-title":"Influence of CRTC1 polymorphisms on body mass index and fat mass in psychiatric patients and the general adult population","volume":"70","author":"Choong","year":"2013","journal-title":"JAMA Psychiat."},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0045","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/wps.20204","article-title":"Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder","volume":"14","author":"Correll","year":"2015","journal-title":"World Psychiatry: Off. J. World Psychiatr. Assoc."},{"issue":"6","key":"10.1016\/j.gene.2017.07.005_bb0050","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.eurpsy.2009.01.005","article-title":"Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of diabetes (EASD) and the European Society of Cardiology (ESC)","volume":"24","author":"De Hert","year":"2009","journal-title":"Eur. Psychiatry"},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0055","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/nrendo.2011.156","article-title":"Metabolic and cardiovascular adverse effects associated with antipsychotic drugs","volume":"8","author":"De Hert","year":"2011","journal-title":"Nat. Rev. Endocrinol."},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0060","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/nrendo.2011.156","article-title":"Metabolic and cardiovascular adverse effects associated with antipsychotic drugs","volume":"8","author":"De Hert","year":"2012","journal-title":"Nat. Rev. Endocrinol."},{"issue":"10","key":"10.1016\/j.gene.2017.07.005_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0139155","article-title":"Influence of MCHR2 and MCHR2-AS1 genetic polymorphisms on body mass index in psychiatric patients and in population-based subjects with present or past atypical depression","volume":"10","author":"Delacretaz","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.gene.2017.07.005_bb0070","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.bbrc.2014.08.120","article-title":"Interleukin-27 inhibits foam cell formation by promoting macrophage ABCA1 expression through JAK2\/STAT3 pathway","volume":"452","author":"Fu","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"4","key":"10.1016\/j.gene.2017.07.005_bb0075","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s10038-005-0240-1","article-title":"Association of nucleotide variations in the apolipoprotein B48 receptor gene (APOB48R) with hypercholesterolemia","volume":"50","author":"Fujita","year":"2005","journal-title":"J. Hum. Genet."},{"issue":"12","key":"10.1016\/j.gene.2017.07.005_bb0080","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1038\/mp.2016.3","article-title":"A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression","volume":"21","author":"Goldsmith","year":"2016","journal-title":"Mol. Psychiatry"},{"issue":"9","key":"10.1016\/j.gene.2017.07.005_bb0085","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1523\/JNEUROSCI.5273-07.2008","article-title":"Induction of activating transcription factors (ATFs) ATF2, ATF3, and ATF4 in the nucleus accumbens and their regulation of emotional behavior","volume":"28","author":"Green","year":"2008","journal-title":"J. Neurosci."},{"issue":"6","key":"10.1016\/j.gene.2017.07.005_bb0090","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1038\/ng.2653","article-title":"The genotype-tissue expression (GTEx) project","volume":"45","author":"GTEx Consortium","year":"2013","journal-title":"Nat. Genet."},{"key":"10.1016\/j.gene.2017.07.005_bb0095","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/1471-2458-9-88","article-title":"The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis","volume":"9","author":"Guh","year":"2009","journal-title":"BMC Public Health"},{"issue":"3","key":"10.1016\/j.gene.2017.07.005_bb0100","doi-asserted-by":"crossref","first-page":"H420","DOI":"10.1152\/ajpheart.00198.2013","article-title":"Interleukin 27 inhibits atherosclerosis via immunoregulation of macrophages in mice","volume":"305","author":"Hirase","year":"2013","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0105","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/nrendo.2014.203","article-title":"Diabetes mellitus and severe mental illness: mechanisms and clinical implications","volume":"11","author":"Holt","year":"2015","journal-title":"Nat. Rev. Endocrinol."},{"issue":"23","key":"10.1016\/j.gene.2017.07.005_bb0110","doi-asserted-by":"crossref","first-page":"13084","DOI":"10.1073\/pnas.241368698","article-title":"Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein","volume":"98","author":"Huang","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.gene.2017.07.005_bb0115","doi-asserted-by":"crossref","first-page":"506283","DOI":"10.1155\/2012\/506283","article-title":"Elevated circulating interleukin-27 in patients with coronary artery disease is associated with dendritic cells, oxidized low-density lipoprotein, and severity of coronary artery stenosis","volume":"2012","author":"Jin","year":"2012","journal-title":"Mediat. Inflamm."},{"issue":"4","key":"10.1016\/j.gene.2017.07.005_bb0120","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1192\/bjp.bp.109.076935","article-title":"Treatment with antipsychotics and the risk of diabetes in clinical practice","volume":"197","author":"Kessing","year":"2010","journal-title":"Br. J. Psychiatry J. Ment. Sci."},{"key":"10.1016\/j.gene.2017.07.005_bb0125","doi-asserted-by":"crossref","first-page":"273060","DOI":"10.1155\/2014\/273060","article-title":"Minimizing cardiovascular adverse effects of atypical antipsychotic drugs in patients with schizophrenia","volume":"2014","author":"Khasawneh","year":"2014","journal-title":"Cardiol. Res. Pract."},{"issue":"8","key":"10.1016\/j.gene.2017.07.005_bb0130","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/ng.866","article-title":"Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile","volume":"43","author":"Kilpelainen TO","year":"2011","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.gene.2017.07.005_bb0135","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/ki.1994.249","article-title":"High glucose elevates c-fos and c-jun transcripts and proteins in mesangial cell cultures","volume":"46","author":"Kreisberg","year":"1994","journal-title":"Kidney Int."},{"issue":"3","key":"10.1016\/j.gene.2017.07.005_bb0140","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/sj.npp.1300357","article-title":"ATF2, a member of the CREB\/ATF family of transcription factors, in chronic stress and consequent to antidepressant treatment: animal models and human post-mortem brains","volume":"29","author":"Laifenfeld","year":"2004","journal-title":"Neuropsychopharmacol: Off. Publ. Am. Coll. Neuropsychopharmacol."},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0145","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/YCO.0b013e32835035ca","article-title":"Life expectancy and cardiovascular mortality in persons with schizophrenia","volume":"25","author":"Laursen","year":"2012","journal-title":"Curr. Opin. Psychiatry"},{"issue":"3","key":"10.1016\/j.gene.2017.07.005_bb0150","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/mp.2011.109","article-title":"Pharmacogenetics of antipsychotic-induced weight gain: review and clinical implications","volume":"17","author":"Lett","year":"2012","journal-title":"Mol. Psychiatry"},{"issue":"9896","key":"10.1016\/j.gene.2017.07.005_bb0155","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0140-6736(13)60733-3","article-title":"Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis","volume":"382","author":"Leucht","year":"2013","journal-title":"Lancet"},{"issue":"7538","key":"10.1016\/j.gene.2017.07.005_bb0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/nature14177","article-title":"Genetic studies of body mass index yield new insights for obesity biology","volume":"518","author":"Locke","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.gene.2017.07.005_bb0165","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.pnpbp.2013.05.005","article-title":"Obesity and psychiatric disorders: commonalities in dysregulated biological pathways and their implications for treatment","volume":"45","author":"Lopresti","year":"2013","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.gene.2017.07.005_bb0170","doi-asserted-by":"crossref","first-page":"10495","DOI":"10.1038\/ncomms10495","article-title":"New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk","volume":"7","author":"Lu","year":"2016","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.gene.2017.07.005_bb0175","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1023\/A:1025635913927","article-title":"Genetic and environmental factors in relative body weight and human adiposity","volume":"27","author":"Maes","year":"1997","journal-title":"Behav. Genet."},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0180","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/nn.3922","article-title":"Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways","volume":"18","author":"Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium","year":"2015","journal-title":"Nat. Neurosci."},{"issue":"Suppl. 1","key":"10.1016\/j.gene.2017.07.005_bb0185","first-page":"20","article-title":"Metabolic considerations in the use of antipsychotic medications: a review of recent evidence","volume":"68","author":"Newcomer","year":"2007","journal-title":"J. Clin. Psychiatry"},{"issue":"12","key":"10.1016\/j.gene.2017.07.005_bb0190","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1111\/j.1753-4887.2008.00128.x","article-title":"Gene-environment interaction and obesity","volume":"66","author":"Qi","year":"2008","journal-title":"Nutr. Rev."},{"issue":"5","key":"10.1016\/j.gene.2017.07.005_bb0195","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/FPC.0000000000000131","article-title":"Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments","volume":"25","author":"Quteineh","year":"2015","journal-title":"Pharmacogenet. Genomics"},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0200","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1172\/JCI29417","article-title":"Neuronal SH2B1 is essential for controlling energy and glucose homeostasis","volume":"117","author":"Ren","year":"2007","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.gene.2017.07.005_bb0205","doi-asserted-by":"crossref","first-page":"511","DOI":"10.4239\/wjd.v5.i4.511","article-title":"SH2B1 regulation of energy balance, body weight, and glucose metabolism","volume":"5","author":"Rui","year":"2014","journal-title":"World J. Diabetes"},{"issue":"3","key":"10.1016\/j.gene.2017.07.005_bb0210","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.pnpbp.2006.12.021","article-title":"759 C\/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment","volume":"31","author":"Ryu","year":"2007","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.gene.2017.07.005_bb0215","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1097\/JCP.0000000000000388","article-title":"Association of PCK1 with body mass index and other metabolic features in patients with psychotropic treatments","volume":"35","author":"Saigi-Morgui","year":"2015","journal-title":"J. Clin. Psychopharmacol."},{"issue":"7510","key":"10.1016\/j.gene.2017.07.005_bb0220","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/nature13595","article-title":"Biological insights from 108 schizophrenia-associated genetic loci","volume":"511","author":"Schizophrenia Working Group of the Psychiatric Genomics Consortium","year":"2014","journal-title":"Nature"},{"issue":"4","key":"10.1016\/j.gene.2017.07.005_bb0225","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1176\/appi.ajp.159.4.561","article-title":"Association of diabetes mellitus with use of atypical neuroleptics in the treatment of schizophrenia","volume":"159","author":"Sernyak","year":"2002","journal-title":"Am. J. Psychiatry"},{"issue":"12","key":"10.1016\/j.gene.2017.07.005_bb0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0083269","article-title":"Hepatic SH2B1 and SH2B2 regulate liver lipid metabolism and VLDL secretion in mice","volume":"8","author":"Sheng","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.gene.2017.07.005_bb0235","series-title":"Stahl's Essential Psychopharmacology - Neuroscientific Basis and Practical Applications","first-page":"1","author":"Stahl","year":"2008"},{"issue":"9","key":"10.1016\/j.gene.2017.07.005_bb0240","doi-asserted-by":"crossref","first-page":"3315","DOI":"10.1210\/en.2013-2148","article-title":"Rab5 activity regulates GLUT4 sorting into insulin-responsive and non-insulin-responsive endosomal compartments: a potential mechanism for development of insulin resistance","volume":"155","author":"Tessneer","year":"2014","journal-title":"Endocrinology"},{"issue":"25","key":"10.1016\/j.gene.2017.07.005_bb0245","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1161\/circ.106.25.3143","article-title":"Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report","volume":"106","author":"Third Report of the National Cholesterol Education Program (NCEP)","year":"2002","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.gene.2017.07.005_bb0250","doi-asserted-by":"crossref","first-page":"e1417","DOI":"10.4088\/JCP.14m09358","article-title":"Importance of early weight changes to predict long-term weight gain during psychotropic drug treatment","volume":"76","author":"Vandenberghe","year":"2015","journal-title":"J. Clin. Psychiatry"},{"issue":"1","key":"10.1016\/j.gene.2017.07.005_bb0255","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ajhg.2011.11.029","article-title":"Five years of GWAS discovery","volume":"90","author":"Visscher","year":"2012","journal-title":"Am. J. Hum. Genet."},{"issue":"8","key":"10.1016\/j.gene.2017.07.005_bb0260","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002793","article-title":"The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits","volume":"8","author":"Voight","year":"2012","journal-title":"PLoS Genet."},{"issue":"1","key":"10.1016\/j.gene.2017.07.005_bb0265","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s13073-015-0225-4","article-title":"Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers","volume":"7","author":"Voisin","year":"2015","journal-title":"Genome Med."},{"issue":"2","key":"10.1016\/j.gene.2017.07.005_bb0270","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/ng829","article-title":"Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice","volume":"30","author":"Yamauchi","year":"2002","journal-title":"Nat. Genet."},{"issue":"12","key":"10.1016\/j.gene.2017.07.005_bb0275","doi-asserted-by":"crossref","first-page":"2702","DOI":"10.1016\/j.biocel.2008.06.012","article-title":"c-Jun N-terminal kinase pathways in diabetes","volume":"40","author":"Yang","year":"2008","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"5","key":"10.1016\/j.gene.2017.07.005_bb0280","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003520","article-title":"Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits","volume":"9","author":"Zaitlen","year":"2013","journal-title":"PLoS Genet."},{"issue":"6","key":"10.1016\/j.gene.2017.07.005_bb0285","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.celrep.2015.04.018","article-title":"Regulation of liver metabolism by the endosomal GTPase Rab5","volume":"11","author":"Zeigerer","year":"2015","journal-title":"Cell Rep."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111917305164?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111917305164?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,29]],"date-time":"2019-09-29T00:33:37Z","timestamp":1569717217000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111917305164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":57,"alternative-id":["S0378111917305164"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2017.07.005","relation":{},"ISSN":["0378-1119"],"issn-type":[{"type":"print","value":"0378-1119"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of variants in SH2B1 and RABEP1 with worsening of low-density lipoprotein and glucose parameters in patients treated with psychotropic drugs","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2017.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}