{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T01:02:15Z","timestamp":1767920535840,"version":"3.49.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1016\/j.gene.2020.144965","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T11:39:16Z","timestamp":1594985956000},"page":"144965","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Silencing ICAM-1 reduces the adhesion of vascular endothelial cells in mice with immunologic contact urticaria"],"prefix":"10.1016","volume":"760","author":[{"given":"Gaomei","family":"Lv","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingang","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2020.144965_b0005","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/j.1610-0387.2007.06538.x","article-title":"Immunologic principles of allergic disease","volume":"11","author":"Averbeck","year":"2007","journal-title":"J. Dtsch. Dermatol. Ges."},{"key":"10.1016\/j.gene.2020.144965_b0010","doi-asserted-by":"crossref","unstructured":"Chang, L., Gong, F., Cui, Y., 2015. RNAi-mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non-small lung cancer in vitro and in vivo. Mol Med Rep volume(1), 1197-1204.","DOI":"10.3892\/mmr.2015.3477"},{"key":"10.1016\/j.gene.2020.144965_b0015","article-title":"Adiponectin enhances intercellular adhesion molecule-1 expression and promotes monocyte adhesion in human synovial fibroblasts","volume":"3","author":"Chen","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.gene.2020.144965_b0020","doi-asserted-by":"crossref","unstructured":"Choudhary, D., Hegde, P., Voznesensky, O., Choudhary, S., Kopsiaftis, S., Claffey, K.P., Pilbeam, C.C., Taylor, J.A., 3rd, 2015. Increased expression of L-selectin (CD62L) in high-grade urothelial carcinoma: A potential marker for metastatic disease. Urol Oncol volume(9), 387 e317-327.","DOI":"10.1016\/j.urolonc.2014.12.009"},{"key":"10.1016\/j.gene.2020.144965_b0025","unstructured":"G., Marseglia, G.L., 2015. Serum immunoglobulin IgE in a pediatric population: a retrospective analysis. J. Biol. Regul. Homeost. Agents volume(2 Suppl 1), 64-69."},{"key":"10.1016\/j.gene.2020.144965_b0030","doi-asserted-by":"crossref","first-page":"4833","DOI":"10.1038\/s41598-017-04687-5","article-title":"Eosinophil cationic protein (ECP), a predictive marker of bullous pemphigoid severity and outcome","volume":"1","author":"Giusti","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.gene.2020.144965_b0035","doi-asserted-by":"crossref","first-page":"108","DOI":"10.5114\/pdia.2014.40915","article-title":"Contact urticaria syndrome caused by haptens","volume":"2","author":"Gomulka","year":"2014","journal-title":"Postepy Dermatol. Alergol."},{"key":"10.1016\/j.gene.2020.144965_b0040","first-page":"101","article-title":"Alterations in neutrophil surface expression of L-selectin (CD62L) and soluble L-selectin (sL-selectin) in hemodialysis patients: relation to HCV","volume":"2","author":"Hassoba","year":"2007","journal-title":"Egypt. J. Immunol."},{"key":"10.1016\/j.gene.2020.144965_b0045","first-page":"92","article-title":"Detection of eosinophil cationic protein and E-selectin in serum and nasal lavage fluid in patients with allergic rhinitis","volume":"2","author":"Hong","year":"2003","journal-title":"Zhonghua Er Bi Yan Hou Ke Za Zhi"},{"key":"10.1016\/j.gene.2020.144965_b0050","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jss.2013.11.001","article-title":"Intercellular adhesion molecule-1 mediates murine colon adenocarcinoma invasion","volume":"1","author":"Howard","year":"2014","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.gene.2020.144965_b0055","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1016\/j.molimm.2010.03.005","article-title":"Differential ICAM-1 isoform expression regulates the development and progression of experimental autoimmune encephalomyelitis","volume":"9","author":"Hu","year":"2010","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.gene.2020.144965_b0060","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.immuni.2009.09.002","article-title":"Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases","volume":"4","author":"Hu","year":"2009","journal-title":"Immunity"},{"key":"10.1016\/j.gene.2020.144965_b0065","first-page":"625","article-title":"Human epicardial fat expresses glucagon-like peptide 1 and 2 receptors genes","volume":"8","author":"Iacobellis","year":"2017","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.gene.2020.144965_b0070","doi-asserted-by":"crossref","first-page":"591","DOI":"10.4103\/0378-6323.100561","article-title":"The clinical significance of immunological contact urticaria to processed grains","volume":"5","author":"Ismail","year":"2012","journal-title":"Indian J. Dermatol. Venereol. Leprol."},{"key":"10.1016\/j.gene.2020.144965_b0075","doi-asserted-by":"crossref","first-page":"8529","DOI":"10.1002\/anie.201203263","article-title":"Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo","volume":"34","author":"Jayaraman","year":"2012","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1016\/j.gene.2020.144965_b0080","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/(SICI)1099-1263(199711\/12)17:6<357::AID-JAT447>3.0.CO;2-2","article-title":"Trimellitic anhydride-sensitive mouse as an animal model for contact urticaria","volume":"6","author":"Lauerma","year":"1997","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.gene.2020.144965_b0085","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.iac.2013.09.005","article-title":"Immunologic contact urticaria","volume":"1","author":"McFadden","year":"2014","journal-title":"Immunol. Allergy Clin. North Am."},{"key":"10.1016\/j.gene.2020.144965_b0090","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0889-1591(03)00055-2","article-title":"Immune cell CD62L and CD11a expression in response to a psychological stressor in human hypertension","volume":"4","author":"Mills","year":"2003","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.gene.2020.144965_b0095","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1600-0536.2010.01763.x","article-title":"Evidence-based guidelines for the prevention, identification and management of occupational contact dermatitis and urticaria","volume":"4","author":"Nicholson","year":"2010","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.gene.2020.144965_b0100","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1365-2249.2009.03892.x","article-title":"Poly I:C-induced expression of intercellular adhesion molecule-1 in intestinal epithelial cells","volume":"2","author":"Omagari","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.gene.2020.144965_b0105","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.atherosclerosis.2003.11.003","article-title":"Biological determinants of serum ICAM-1, E-selectin, P-selectin and L-selectin levels in healthy subjects: the Stanislas study","volume":"2","author":"Ponthieux","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.gene.2020.144965_b0110","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0076-6879(08)02003-X","article-title":"Endothelial cell adhesion and migration","author":"Reinhart-King","year":"2008","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.gene.2020.144965_b0115","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.4049\/jimmunol.0902023","article-title":"Inflammatory cytokine-induced intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in mesenchymal stem cells are critical for immunosuppression","volume":"5","author":"Ren","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.gene.2020.144965_b0120","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1038\/mt.2008.91","article-title":"Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells","volume":"7","author":"Ritprajak","year":"2008","journal-title":"Mol. Ther."},{"key":"10.1016\/j.gene.2020.144965_b0125","first-page":"342ra380","article-title":"RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction","volume":"342","author":"Sager","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.gene.2020.144965_b0130","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.4049\/jimmunol.0901860","article-title":"IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation","volume":"6","author":"Sehra","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.gene.2020.144965_b0135","doi-asserted-by":"crossref","first-page":"4325","DOI":"10.4049\/jimmunol.170.8.4325","article-title":"L-selectin or ICAM-1 deficiency reduces an immediate-type hypersensitivity response by preventing mast cell recruitment in repeated elicitation of contact hypersensitivity","volume":"8","author":"Shimada","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.gene.2020.144965_b0140","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.revmed.2014.01.008","article-title":"Urticaria: diagnosis and treatment","volume":"9","author":"Soria","year":"2014","journal-title":"Rev. Med. Interne"},{"key":"10.1016\/j.gene.2020.144965_b0145","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1139\/h2012-034","article-title":"Moderate-intensity, premeal cycling blunts postprandial increases in monocyte cell surface CD18 and CD11a and endothelial microparticles following a high-fat meal in young adults","volume":"3","author":"Strohacker","year":"2012","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"10.1016\/j.gene.2020.144965_b0150","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1034\/j.1398-9995.2000.00623.x","article-title":"Effects of human lung fibroblasts on eosinophil degranulation","volume":"12","author":"Takafuji","year":"2000","journal-title":"Allergy"},{"key":"10.1016\/j.gene.2020.144965_b0155","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1002\/ijc.28066","article-title":"Intercellular adhesion molecule-1 (ICAM-1) expression correlates with oral cancer progression and induces macrophage\/cancer cell adhesion","volume":"3","author":"Usami","year":"2013","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.gene.2020.144965_b0160","doi-asserted-by":"crossref","first-page":"5687","DOI":"10.1128\/JVI.00611-15","article-title":"HIV-1 Nef and Vpu interfere with L-selectin (CD62L) cell surface expression to inhibit adhesion and signaling in infected CD4+ T lymphocytes","volume":"10","author":"Vassena","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.gene.2020.144965_b0165","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/cod.12679","article-title":"Cosmetic components causing contact urticaria: a review and update","volume":"6","author":"Verhulst","year":"2016","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.gene.2020.144965_b0170","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1046\/j.1365-2230.2001.00780.x","article-title":"Contact urticaria","volume":"2","author":"Wakelin","year":"2001","journal-title":"Clin. Exp. Dermatol."},{"key":"10.1016\/j.gene.2020.144965_b0175","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3109\/15569527.2012.727519","article-title":"Immunologic contact urticaria\u2013the human touch","volume":"2","author":"Wang","year":"2013","journal-title":"Cutan. Ocul. Toxicol."},{"key":"10.1016\/j.gene.2020.144965_b0180","first-page":"479","article-title":"Effect of intercellular adhesion molecule-1 on the migration in vitro of murine mesenchymal stem cells and its related mechanism","volume":"2","author":"Wang","year":"2014","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi"},{"key":"10.1016\/j.gene.2020.144965_b0185","doi-asserted-by":"crossref","unstructured":"Wedi, B., Wieczorek, D., Raap, U., Kapp, A., 2014. Urticaria. J Dtsch Dermatol Ges volume(11), 997-1007; quiz 1008-1009.","DOI":"10.1111\/ddg.12441"},{"key":"10.1016\/j.gene.2020.144965_b0190","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1006\/clim.1999.4775","article-title":"Blocking ICAM-1 (CD54) and LFA-1 (CD11a) inhibits experimental allergic conjunctivitis","volume":"2","author":"Whitcup","year":"1999","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.gene.2020.144965_b0195","first-page":"282","article-title":"Expression of ICAM-1 (CD54) in pediatric tumor and acute leukemia and its clinic significance in immunotherapy with CIK cell","volume":"2","author":"Xiong","year":"2012","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi"},{"key":"10.1016\/j.gene.2020.144965_b0200","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1038\/cgt.2013.44","article-title":"Decreasing P-selectin and ICAM-1 via activating Akt: a possible mechanism by which PARG inhibits adhesion of mouse colorectal carcinoma CT26 cells to platelets","volume":"9","author":"Yan","year":"2013","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.gene.2020.144965_b0205","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1111\/jcmm.13040","article-title":"CARD9 gene silencing with siRNA protects rats against severe acute pancreatitis: CARD9-dependent NF-kappaB and P38MAPKs pathway","volume":"6","author":"Yang","year":"2017","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.gene.2020.144965_b0210","doi-asserted-by":"crossref","first-page":"R227","DOI":"10.1186\/ar3214","article-title":"RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1","volume":"6","author":"Zhao","year":"2010","journal-title":"Arthritis Res. Ther."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037811192030634X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S037811192030634X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T16:34:23Z","timestamp":1759854863000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S037811192030634X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":42,"alternative-id":["S037811192030634X"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2020.144965","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Silencing ICAM-1 reduces the adhesion of vascular endothelial cells in mice with immunologic contact urticaria","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2020.144965","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"144965"}}