{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T00:28:59Z","timestamp":1759883339611,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2020R1A2C4002594","NRF- 2018R1D1A1B07048092"],"award-info":[{"award-number":["2020R1A2C4002594","NRF- 2018R1D1A1B07048092"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.gene.2022.146822","type":"journal-article","created":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T11:27:59Z","timestamp":1660908479000},"page":"146822","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Downregulated miRNAs associated with auditory deafferentation and compensatory neural plastic changes following single-sided deafness in the inferior colliculi of rats"],"prefix":"10.1016","volume":"845","author":[{"given":"Chang","family":"Ho Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung","family":"Woon Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So","family":"Min Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So","family":"Young Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.gene.2022.146822_b0005","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/j.neuroscience.2006.04.058","article-title":"Modulation of inhibitory and excitatory synaptic transmission in rat inferior colliculus after unilateral cochleectomy: an in situ and immunofluorescence study","volume":"141","author":"Argence","year":"2006","journal-title":"Neuroscience"},{"key":"10.1016\/j.gene.2022.146822_b0010","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1111\/j.1460-9568.2008.06454.x","article-title":"Stimulation by cochlear implant in unilaterally deaf rats reverses the decrease of inhibitory transmission in the inferior colliculus","volume":"28","author":"Argence","year":"2008","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.gene.2022.146822_b0015","article-title":"The miR-132\/212 locus: a complex regulator of neuronal plasticity, gene expression and cognition","volume":"3","author":"Aten","year":"2016","journal-title":"RNA Dis"},{"key":"10.1016\/j.gene.2022.146822_b0020","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.neuropharm.2018.10.020","article-title":"miR-132\/212 is induced by stress and its dysregulation triggers anxiety-related behavior","volume":"144","author":"Aten","year":"2019","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.gene.2022.146822_b0025","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.neuroscience.2018.08.023","article-title":"Synergistic Transcriptional Changes in AMPA and GABAA Receptor Genes Support Compensatory Plasticity Following Unilateral Hearing Loss","volume":"407","author":"Balaram","year":"2019","journal-title":"Neuroscience"},{"key":"10.1016\/j.gene.2022.146822_b0030","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1038\/nature09271","article-title":"A novel pathway regulates memory and plasticity via SIRT1 and miR-134","volume":"466","author":"Gao","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.gene.2022.146822_b0035","article-title":"Ear-Specific Hemispheric Asymmetry in Unilateral Deafness Revealed by Auditory Cortical Activity","volume":"15","author":"Han","year":"2021","journal-title":"Front Neurosci"},{"key":"10.1016\/j.gene.2022.146822_b0040","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1080\/00016480802455283","article-title":"Changes in calbindin-D28k and parvalbumin expression in the superior olivary complex following unilateral cochlear ablation in neonatal rats","volume":"129","author":"Hatano","year":"2009","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.gene.2022.146822_b0045","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/cne.21002","article-title":"Deafferentation induces novel axonal projections in the auditory brainstem after hearing onset","volume":"497","author":"Hsieh","year":"2006","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.gene.2022.146822_b0050","doi-asserted-by":"crossref","first-page":"133","DOI":"10.14336\/AD.2017.0119","article-title":"MicroRNAs and Presbycusis","volume":"9","author":"Hu","year":"2018","journal-title":"Aging Dis"},{"key":"10.1016\/j.gene.2022.146822_b0055","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/s41419-019-1809-5","article-title":"miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson's disease","volume":"10","author":"Hu","year":"2019","journal-title":"Cell Death Dis."},{"issue":"2","key":"10.1016\/j.gene.2022.146822_b0060","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.jprot.2011.08.007","article-title":"Noise induced changes in the expression of p38\/MAPK signaling proteins in the sensory epithelium of the inner ear","volume":"75","author":"Jamesdaniel","year":"2011","journal-title":"J. Proteomics"},{"issue":"3","key":"10.1016\/j.gene.2022.146822_b0065","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s10528-021-10034-1","article-title":"Changes in the Gene Expression Profiles of the Inferior Colliculus Following Unilateral Cochlear Ablation in Adult Rats","volume":"59","author":"Kil","year":"2021","journal-title":"Biochem Genet"},{"key":"10.1016\/j.gene.2022.146822_b0070","doi-asserted-by":"crossref","first-page":"8624745","DOI":"10.1155\/2018\/8624745","article-title":"Neural Plastic Changes in the Subcortical Auditory Neural Pathway after Single-Sided Deafness in Adult Mice: A MEMRI Study","volume":"2018","author":"Kim","year":"2018","journal-title":"Biomed. Res.Int"},{"key":"10.1016\/j.gene.2022.146822_b0075","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1093\/brain\/aws305","article-title":"Single-sided deafness leads to unilateral aural preference within an early sensitive period","volume":"136","author":"Kral","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.gene.2022.146822_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.mcp.2019.101497","article-title":"MiR-202-5p attenuates neurological deficits and neuronal injury in MCAO model rats and OGD-induced injury in Neuro-2a cells by targeting eIF4E-mediated induction of autophagy and inhibition of Akt\/GSK-3beta pathway","volume":"51","author":"Li","year":"2020","journal-title":"Mol Cell Probes"},{"issue":"6","key":"10.1016\/j.gene.2022.146822_b0085","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1111\/1440-1681.13265","article-title":"Inhibition of microRNA-199a-5p ameliorates oxygen-glucose deprivation\/reoxygenation-induced apoptosis and oxidative stress in HT22 neurons by targeting Brg1 to activate Nrf2\/HO-1 signalling","volume":"47","author":"Li","year":"2020","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.gene.2022.146822_b0090","article-title":"miR-15b reduces amyloid-beta accumulation in SH-SY5Y cell line through targetting NF-kappaB signaling and BACE1","volume":"38","author":"Li","year":"2018","journal-title":"Biosci Rep"},{"key":"10.1016\/j.gene.2022.146822_b0095","first-page":"1729","article-title":"miR1345p\/Foxp2\/Syn1 is involved in cognitive impairment in an early vascular dementia rat model","volume":"44","author":"Liu","year":"2019","journal-title":"Int J Mol Med"},{"key":"10.1016\/j.gene.2022.146822_b0100","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.neuroscience.2020.04.010","article-title":"Dynamic Changes in Synaptic Plasticity Genes in Ipsilateral and Contralateral Inferior Colliculus Following Unilateral Noise-induced Hearing Loss","volume":"436","author":"Manohar","year":"2020","journal-title":"Neuroscience"},{"key":"10.1016\/j.gene.2022.146822_b0105","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.gene.2018.10.075","article-title":"Role of microRNAs in inner ear development and hearing loss","volume":"686","author":"Mittal","year":"2019","journal-title":"Gene"},{"key":"10.1016\/j.gene.2022.146822_b0110","doi-asserted-by":"crossref","first-page":"76","DOI":"10.21053\/ceo.2019.01382","article-title":"MicroRNAs Related to Cognitive Impairment After Hearing Loss","volume":"14","author":"Mun","year":"2021","journal-title":"Clin Exp Otorhinolaryngol"},{"key":"10.1016\/j.gene.2022.146822_b0115","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21228792","article-title":"Changes in microRNA Expression in the Cochlear Nucleus and Inferior Colliculus after Acute Noise-Induced Hearing Loss","volume":"21","author":"Park","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"1-2","key":"10.1016\/j.gene.2022.146822_b0120","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0378-5955(01)00214-3","article-title":"Plasticity in the adult human central auditory system: evidence from late-onset profound unilateral deafness","volume":"154","author":"Ponton","year":"2001","journal-title":"Hear. Res."},{"key":"10.1016\/j.gene.2022.146822_b0125","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3389\/fncel.2017.00276","article-title":"MicroRNAs in Hearing Disorders: Their Regulation by Oxidative Stress, Inflammation and Antioxidants","volume":"11","author":"Prasad","year":"2017","journal-title":"Front Cell Neurosci"},{"issue":"8","key":"10.1016\/j.gene.2022.146822_b0130","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1093\/cercor\/bhm206","article-title":"Cochlear implants stimulate activity-dependent CREB pathway in the deaf auditory cortex: implications for molecular plasticity induced by neural prosthetic devices","volume":"18","author":"Tan","year":"2008","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.gene.2022.146822_b0135","article-title":"LncRNA Snhg8 attenuates microglial inflammation response and blood-brain barrier damage in ischemic stroke through regulating miR-425-5p mediated SIRT1\/NF-kappaB signaling","volume":"e22724","author":"Tian","year":"2021","journal-title":"J Biochem Mol Toxicol"},{"key":"10.1016\/j.gene.2022.146822_b0140","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.neurobiolaging.2019.03.013","article-title":"Modulation of miR-34a\/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis","volume":"79","author":"Xiong","year":"2019","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.gene.2022.146822_b0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxlet.2020.11.001","article-title":"Downregulation of microRNA-199a-5p alleviated lidocaine-induced sensory dysfunction and spinal cord myelin lesions in a rat model","volume":"336","author":"Zhang","year":"2021","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.gene.2022.146822_b0150","first-page":"6549","article-title":"MiR-199a-5p inhibition protects cognitive function of ischemic stroke rats by AKT signaling pathway","volume":"12","author":"Zhang","year":"2020","journal-title":"Am J Transl Res"}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111922006412?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111922006412?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T16:57:08Z","timestamp":1759856228000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111922006412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":30,"alternative-id":["S0378111922006412"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2022.146822","relation":{},"ISSN":["0378-1119"],"issn-type":[{"type":"print","value":"0378-1119"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Downregulated miRNAs associated with auditory deafferentation and compensatory neural plastic changes following single-sided deafness in the inferior colliculi of rats","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2022.146822","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"146822"}}