{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T03:32:43Z","timestamp":1772854363347,"version":"3.50.1"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003968","name":"Iran National Science Foundation","doi-asserted-by":"publisher","award":["99019617"],"award-info":[{"award-number":["99019617"]}],"id":[{"id":"10.13039\/501100003968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008091","name":"Golestan University of Medical Sciences","doi-asserted-by":"publisher","award":["111338"],"award-info":[{"award-number":["111338"]}],"id":[{"id":"10.13039\/501100008091","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.gene.2023.147598","type":"journal-article","created":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T01:58:09Z","timestamp":1688003889000},"page":"147598","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Positive effect of miR-2392 on fibroblast to cardiomyocyte-like cell fate transition: An in silico and in vitro study"],"prefix":"10.1016","volume":"879","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4559-2455","authenticated-orcid":false,"given":"Mahdi","family":"Aalikhani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrdad","family":"Alikhani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Safoura","family":"Khajeniazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayyoob","family":"Khosravi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Bazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anvarsadat","family":"Kianmehr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2023.147598_b0005","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.bbrc.2021.07.076","article-title":"In silico drug repurposing for the treatment of heart diseases using gene expression data and molecular docking techniques","volume":"572","author":"Aalikhani","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.gene.2023.147598_b0010","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.stemcr.2017.01.025","article-title":"Notch inhibition enhances cardiac reprogramming by increasing MEF2C transcriptional activity","volume":"8","author":"Abad","year":"2017","journal-title":"Stem Cell Rep."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0015","first-page":"5","article-title":"Forskolin and derivatives as tools for studying the role of cAMP","volume":"67","author":"Alasbahi","year":"2012","journal-title":"Die Pharmazie- Int. J. Pharm. Sci."},{"issue":"D1","key":"10.1016\/j.gene.2023.147598_b0020","doi-asserted-by":"crossref","first-page":"D991","DOI":"10.1093\/nar\/gks1193","article-title":"NCBI GEO: archive for functional genomics data sets\u2014update","volume":"41","author":"Barrett","year":"2012","journal-title":"Nucl. Acids Res."},{"issue":"6","key":"10.1016\/j.gene.2023.147598_b0025","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1136\/archdischild-2013-304340","article-title":"What is next generation sequencing?","volume":"98","author":"Behjati","year":"2013","journal-title":"Arch. Dis. Childhood-Educ. Practice"},{"issue":"4","key":"10.1016\/j.gene.2023.147598_b0030","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/j.ymthe.2022.01.031","article-title":"miR-486 attenuates cardiac ischemia\/reperfusion injury and mediates the beneficial effect of exercise for myocardial protection","volume":"30","author":"Bei","year":"2022","journal-title":"Mol. Ther."},{"issue":"10","key":"10.1016\/j.gene.2023.147598_b0035","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1161\/CIR.0000000000000659","article-title":"Heart disease and stroke statistics-2019 update: a report from the American Heart Association","volume":"139","author":"Benjamin","year":"2019","journal-title":"Circulation"},{"issue":"6290","key":"10.1016\/j.gene.2023.147598_b0040","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1126\/science.aaf1502","article-title":"Conversion of human fibroblasts into functional cardiomyocytes by small molecules","volume":"352","author":"Cao","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.gene.2023.147598_b0045","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.biomaterials.2018.11.034","article-title":"Efficient in vivo direct conversion of fibroblasts into cardiomyocytes using a nanoparticle-based gene carrier","volume":"192","author":"Chang","year":"2019","journal-title":"Biomaterials"},{"issue":"W1","key":"10.1016\/j.gene.2023.147598_b0050","doi-asserted-by":"crossref","first-page":"W244","DOI":"10.1093\/nar\/gkaa467","article-title":"miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology","volume":"48","author":"Chang","year":"2020","journal-title":"Nucleic Acids Res."},{"issue":"4","key":"10.1016\/j.gene.2023.147598_b0055","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.hjc.2017.10.002","article-title":"Circulating microRNAs as novel biomarkers for heart failure","volume":"59","author":"Chen","year":"2018","journal-title":"Hellenic J. Cardiol."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0060","doi-asserted-by":"crossref","first-page":"40285","DOI":"10.1038\/srep40285","article-title":"Core transcription factors, microRNAs, and small molecules drive transdifferentiation of human fibroblasts towards the cardiac cell lineage","volume":"7","author":"Christoforou","year":"2017","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.gene.2023.147598_b0065","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.tcm.2017.01.011","article-title":"Myocardial fibrosis predicts ventricular tachyarrhythmias","volume":"27","author":"Disertori","year":"2017","journal-title":"Trends Cardiovasc. Med."},{"issue":"9","key":"10.1016\/j.gene.2023.147598_b0070","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/cr.2015.99","article-title":"Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails","volume":"25","author":"Fu","year":"2015","journal-title":"Cell Res."},{"key":"10.1016\/j.gene.2023.147598_b0075","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.molimm.2023.01.010","article-title":"Engagement of an optimized lentiviral vector enhances the expression and cytotoxicity of CAR in human NK cells","volume":"155","author":"Guo","year":"2023","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.gene.2023.147598_b0080","series-title":"Genetics: analysis of genes and genomes","author":"Hartl","year":"2009"},{"key":"10.1016\/j.gene.2023.147598_b0085","first-page":"1884","article-title":"miR-208a in cardiac hypertrophy and remodeling","author":"Huang","year":"2021","journal-title":"Front. Cardiovasc. Med."},{"issue":"6","key":"10.1016\/j.gene.2023.147598_b0090","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.tcm.2014.06.003","article-title":"An emerging role for the miR-26 family in cardiovascular disease","volume":"24","author":"Icli","year":"2014","journal-title":"Trends Cardiovasc. Med."},{"issue":"11","key":"10.1016\/j.gene.2023.147598_b0095","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1161\/CIRCRESAHA.112.269035","article-title":"MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes","volume":"110","author":"Jayawardena","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.gene.2023.147598_b0100","series-title":"Stem Cell Transcriptional Networks","first-page":"263","article-title":"Direct reprogramming of cardiac fibroblasts to cardiomyocytes using microRNAs","author":"Jayawardena","year":"2014"},{"issue":"D1","key":"10.1016\/j.gene.2023.147598_b0105","doi-asserted-by":"crossref","first-page":"D545","DOI":"10.1093\/nar\/gkaa970","article-title":"KEGG: integrating viruses and cellular organisms","volume":"49","author":"Kanehisa","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2023.147598_b0110","series-title":"What's in a cardiomyocyte\u2013And how do we make one through reprogramming? Biochimica et Biophysica Acta","author":"Keepers","year":"2019"},{"key":"10.1016\/j.gene.2023.147598_b0115","doi-asserted-by":"crossref","unstructured":"Keepers, B., J. Liu, and L. Qian, What's in a cardiomyocyte\u2013And how do we make one through reprogramming? Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 2020. 1867(3): p. 118464.","DOI":"10.1016\/j.bbamcr.2019.03.011"},{"issue":"D1","key":"10.1016\/j.gene.2023.147598_b0120","doi-asserted-by":"crossref","first-page":"D155","DOI":"10.1093\/nar\/gky1141","article-title":"miRBase: from microRNA sequences to function","volume":"47","author":"Kozomara","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2023.147598_b0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40001-015-0148-y","article-title":"Clinical impact of circulating miR-26a, miR-191, and miR-208b in plasma of patients with acute myocardial infarction","volume":"20","author":"Li","year":"2015","journal-title":"Eur. J. Med. Res."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0130","doi-asserted-by":"crossref","first-page":"38815","DOI":"10.1038\/srep38815","article-title":"Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs","volume":"6","author":"Li","year":"2016","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.gene.2023.147598_b0135","doi-asserted-by":"crossref","first-page":"3774","DOI":"10.1096\/fj.201601140RR","article-title":"MiR-2392 suppresses metastasis and epithelial\u2013mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer","volume":"31","author":"Li","year":"2017","journal-title":"FASEB J."},{"issue":"9","key":"10.1016\/j.gene.2023.147598_b0140","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1093\/cvr\/cvab248","article-title":"MicroRNA-27b-3p down-regulates FGF1 and aggravates pathological cardiac remodelling","volume":"118","author":"Li","year":"2022","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0145","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1161\/CIRCRESAHA.115.304457","article-title":"Pi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival","volume":"116","author":"Lin","year":"2015","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.gene.2023.147598_b0150","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.yjmcc.2011.06.012","article-title":"Methods in cardiomyocyte isolation, culture, and gene transfer","volume":"51","author":"Louch","year":"2011","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"12","key":"10.1016\/j.gene.2023.147598_b0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"issue":"3","key":"10.1016\/j.gene.2023.147598_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109839","article-title":"Role of miR-2392 in driving SARS-CoV-2 infection","volume":"37","author":"McDonald","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.gene.2023.147598_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.yjmcc.2023.02.002","article-title":"Unlocking cardiomyocyte renewal potential for myocardial regeneration therapy","author":"Mehdipour","year":"2023","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.gene.2023.147598_b0170","series-title":"Global atlas on cardiovascular disease prevention and control","author":"Mendis","year":"2011"},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0175","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.stem.2017.11.010","article-title":"Direct in vivo reprogramming with Sendai virus vectors improves cardiac function after myocardial infarction","volume":"22","author":"Miyamoto","year":"2018","journal-title":"Cell Stem Cell"},{"issue":"14","key":"10.1016\/j.gene.2023.147598_b0180","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.15252\/embj.201387605","article-title":"MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures","volume":"33","author":"Muraoka","year":"2014","journal-title":"Embo J."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0185","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/s41467-019-08626-y","article-title":"Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming","volume":"10","author":"Muraoka","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.gene.2023.147598_b0190","doi-asserted-by":"crossref","first-page":"777","DOI":"10.3389\/fphys.2017.00777","article-title":"The processes and mechanisms of cardiac and pulmonary fibrosis","volume":"8","author":"Murtha","year":"2017","journal-title":"Front. Physiol."},{"key":"10.1016\/j.gene.2023.147598_b0195","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3389\/fgene.2014.00099","article-title":"miR-191: an emerging player in disease biology","volume":"5","author":"Nagpal","year":"2014","journal-title":"Front. Genet."},{"issue":"suppl_2","key":"10.1016\/j.gene.2023.147598_b0200","doi-asserted-by":"crossref","first-page":"W163","DOI":"10.1093\/nar\/gkn198","article-title":"IDT SciTools: a suite for analysis and design of nucleic acid oligomers","volume":"36","author":"Owczarzy","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.gene.2023.147598_b0205","first-page":"35","article-title":"Immunohistochemistry and immunocytochemistry","author":"Renshaw","year":"2017","journal-title":"Immunohistochem. Immunocytochem.: Essential Methods"},{"key":"10.1016\/j.gene.2023.147598_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110903","article-title":"miR-1: A comprehensive review of its role in normal development and diverse disorders","volume":"132","author":"Safa","year":"2020","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0215","doi-asserted-by":"crossref","first-page":"289","DOI":"10.32614\/RJ-2016-021","article-title":"mclust 5: clustering, classification and density estimation using Gaussian finite mixture models","volume":"8","author":"Scrucca","year":"2016","journal-title":"The R journal"},{"key":"10.1016\/j.gene.2023.147598_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2016.06.034","article-title":"Effect of biophysical cues on reprogramming to cardiomyocytes","volume":"103","author":"Sia","year":"2016","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0225","doi-asserted-by":"crossref","DOI":"10.1002\/0471143030.cb2104s27","article-title":"Design and use of fluorescent fusion proteins in cell biology","volume":"27","author":"Snapp","year":"2005","journal-title":"Curr. Protoc. Cell Biol."},{"issue":"10","key":"10.1016\/j.gene.2023.147598_b0230","doi-asserted-by":"crossref","first-page":"e0206239","DOI":"10.1371\/journal.pone.0206239","article-title":"miRWalk: An online resource for prediction of microRNA binding sites","volume":"13","author":"Sticht","year":"2018","journal-title":"PLoS one"},{"issue":"7","key":"10.1016\/j.gene.2023.147598_b0235","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1111\/liv.15284","article-title":"miR-2392 functions as tumour suppressor and inhibits malignant progression of hepatocellular carcinoma via directly targeting JAG2","volume":"42","author":"Sun","year":"2022","journal-title":"Liver Int."},{"key":"10.1016\/j.gene.2023.147598_b0240","unstructured":"Team, R.C., R: A language and environment for statistical computing. 2013."},{"issue":"1A","key":"10.1016\/j.gene.2023.147598_b0245","first-page":"A68","article-title":"The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge","volume":"19","author":"Tomczak","year":"2015","journal-title":"Contemp. Oncol."},{"key":"10.1016\/j.gene.2023.147598_b0250","unstructured":"Vandesompele, J., et al., Real-time PCR: current technology and applications. Reference gene validation software for improved normalization, 2009. 2: p. 47-64."},{"issue":"3","key":"10.1016\/j.gene.2023.147598_b0255","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/cr.2011.132","article-title":"Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice","volume":"22","author":"Wang","year":"2012","journal-title":"Cell Res."},{"issue":"5","key":"10.1016\/j.gene.2023.147598_b0260","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.celrep.2014.01.038","article-title":"Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4","volume":"6","author":"Wang","year":"2014","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0265","doi-asserted-by":"crossref","first-page":"23017","DOI":"10.1038\/srep23017","article-title":"Selenium augments microRNA directed reprogramming of fibroblasts to cardiomyocytes via Nanog","volume":"6","author":"Wang","year":"2016","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0270","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1080\/21691401.2019.1617728","article-title":"The long noncoding RNA linc00858 promotes progress of lung cancer through miR-3182\/MMP2 axis","volume":"47","author":"Xue","year":"2019","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"9","key":"10.1016\/j.gene.2023.147598_b0275","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1161\/CIRCULATIONAHA.113.003863","article-title":"Deep RNA sequencing reveals dynamic regulation of myocardial noncoding RNAs in failing human heart and remodeling with mechanical circulatory support","volume":"129","author":"Yang","year":"2014","journal-title":"Circulation"},{"issue":"44","key":"10.1016\/j.gene.2023.147598_b0280","doi-asserted-by":"crossref","first-page":"75844","DOI":"10.18632\/oncotarget.17998","article-title":"MiR-26a contributes to the PDGF-BB-induced phenotypic switch of vascular smooth muscle cells by suppressing Smad1","volume":"8","author":"Yang","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2105-13-S6-S1","article-title":"Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction","volume":"13","author":"Ye","year":"2012","journal-title":"BMC Bioinf."},{"issue":"3","key":"10.1016\/j.gene.2023.147598_b0290","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.stem.2016.02.001","article-title":"Expandable cardiovascular progenitor cells reprogrammed from fibroblasts","volume":"18","author":"Zhang","year":"2016","journal-title":"Cell Stem Cell"},{"issue":"18","key":"10.1016\/j.gene.2023.147598_b0295","doi-asserted-by":"crossref","first-page":"e017970","DOI":"10.1161\/JAHA.120.017970","article-title":"MicroRNA-26a Protects the Heart Against Hypertension-Induced Myocardial Fibrosis","volume":"9","author":"Zhang","year":"2020","journal-title":"J. Am. Heart Assoc."},{"issue":"1","key":"10.1016\/j.gene.2023.147598_b0300","doi-asserted-by":"crossref","first-page":"8243","DOI":"10.1038\/ncomms9243","article-title":"High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling","volume":"6","author":"Zhao","year":"2015","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.gene.2023.147598_b0305","first-page":"15947","article-title":"MAPK1 up-regulates the expression of MALAT1 to promote the proliferation of cardiomyocytes through PI3K\/AKT signaling pathway","volume":"8","author":"Zhao","year":"2015","journal-title":"Int. J. Clin. Exp. Path."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111923004390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111923004390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T17:04:23Z","timestamp":1759856663000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111923004390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":61,"alternative-id":["S0378111923004390"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2023.147598","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Positive effect of miR-2392 on fibroblast to cardiomyocyte-like cell fate transition: An in silico and in vitro study","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2023.147598","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"147598"}}