{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:53:27Z","timestamp":1787496807818,"version":"build-2736575974"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.gene.2024.148199","type":"journal-article","created":{"date-parts":[[2024,1,21]],"date-time":"2024-01-21T01:13:10Z","timestamp":1705799590000},"page":"148199","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Molecular functional characterization of the setdb1 and its potential target gene sox5 illuminate the histone modification-mediated orchestration of gonadal development in Chinese tongue sole (Cynoglossus semilaevis)"],"prefix":"10.1016","volume":"901","author":[{"given":"Bowen","family":"Yue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingyi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxiu","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9443-8019","authenticated-orcid":false,"given":"Changwei","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"21","key":"10.1016\/j.gene.2024.148199_b0005","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1101\/gad.1017802","article-title":"The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6","volume":"16","author":"Akiyama","year":"2002","journal-title":"Genes Dev."},{"issue":"7518","key":"10.1016\/j.gene.2024.148199_b0010","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/nature13726","article-title":"The genomic substrate for adaptive radiation in African cichlid fish","volume":"513","author":"Brawand","year":"2014","journal-title":"Nature"},{"issue":"11","key":"10.1016\/j.gene.2024.148199_b0015","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/nrg.2017.60","article-title":"Vertebrate sex determination: evolutionary plasticity of a fundamental switch","volume":"18","author":"Capel","year":"2017","journal-title":"Nat. Rev. Genet."},{"issue":"7339","key":"10.1016\/j.gene.2024.148199_b0020","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nature09806","article-title":"The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset","volume":"471","author":"Ceol","year":"2011","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.gene.2024.148199_b0025","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/ng.2890","article-title":"Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle","volume":"46","author":"Chen","year":"2014","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.gene.2024.148199_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108575","article-title":"The essential function of SETDB1 in homologous chromosome pairing and synapsis during meiosis","volume":"34","author":"Cheng","year":"2021","journal-title":"Cell Rep."},{"issue":"7","key":"10.1016\/j.gene.2024.148199_b0035","doi-asserted-by":"crossref","first-page":"5563","DOI":"10.1074\/jbc.M410483200","article-title":"In Vitro and in Vivo analyses of a Phe\/Tyr Switch controlling product specificity of histone lysine Methyltransferases","volume":"280","author":"Collins","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.gene.2024.148199_b0040","doi-asserted-by":"crossref","first-page":"42213","DOI":"10.1038\/srep42213","article-title":"Genome editing reveals dmrt1 as an essential male sex-determining gene in Chinese tongue sole (Cynoglossus semilaevis)","volume":"7","author":"Cui","year":"2017","journal-title":"Sci. Rep."},{"issue":"1\u20132","key":"10.1016\/j.gene.2024.148199_b0045","first-page":"209","article-title":"Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development","volume":"407","author":"Daigle","year":"2015","journal-title":"Mol. Cell. Biol."},{"issue":"15","key":"10.1016\/j.gene.2024.148199_b0050","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1242\/dev.132746","article-title":"The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos","volume":"143","author":"Eymery","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.gene.2024.148199_b0055","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1038\/ncomms2995","article-title":"Dynamics of 5-hydroxymethylcytosine during mouse spermatogenesis","volume":"4","author":"Gan","year":"2013","journal-title":"Nat Commun"},{"issue":"5","key":"10.1016\/j.gene.2024.148199_b0060","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/jez.b.21053","article-title":"Molecular cloning, expression of Sox5 and its down-regulation of Dmrt1 transcription in Zebrafish","volume":"304","author":"Gao","year":"2005","journal-title":"J. Exp. Zool. B Mol. Dev. Evol."},{"issue":"6389","key":"10.1016\/j.gene.2024.148199_b0065","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1126\/science.aap8328","article-title":"The histone demethylase KDM6B regulates temperature-dependent sex determination in a turtle species","volume":"360","author":"Ge","year":"2018","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.gene.2024.148199_b0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00013.2015","article-title":"Spermatogenesis: the commitment to meiosis","volume":"96","author":"Griswold","year":"2016","journal-title":"Physiol Rev"},{"issue":"5","key":"10.1016\/j.gene.2024.148199_b0075","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.devcel.2018.10.004","article-title":"SETDB1 links the meiotic DNA damage response to sex chromosome silencing in mice","volume":"47","author":"Hirota","year":"2018","journal-title":"Dev. Cell"},{"issue":"4","key":"10.1016\/j.gene.2024.148199_b0080","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1111\/raq.12554","article-title":"A review on sox genes in fish","volume":"13","author":"Hu","year":"2021","journal-title":"Rev. Aquac."},{"issue":"7664","key":"10.1016\/j.gene.2024.148199_b0085","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nature23267","article-title":"Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription","volume":"547","author":"Jih","year":"2017","journal-title":"Nature"},{"issue":"18","key":"10.1016\/j.gene.2024.148199_b0090","doi-asserted-by":"crossref","first-page":"5234","DOI":"10.1093\/hmg\/ddv244","article-title":"FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis","volume":"24","author":"Kato","year":"2015","journal-title":"Hum. Mol. Genet."},{"issue":"4","key":"10.1016\/j.gene.2024.148199_b0095","doi-asserted-by":"crossref","first-page":"e1005970","DOI":"10.1371\/journal.pgen.1005970","article-title":"Maternal setdb1 is required for meiotic progression and preimplantation development in mouse","volume":"12","author":"Kim","year":"2016","journal-title":"PLoS Genet"},{"issue":"40","key":"10.1016\/j.gene.2024.148199_b0100","doi-asserted-by":"crossref","first-page":"30496","DOI":"10.1074\/jbc.M110.121590","article-title":"Transcriptional regulation of an axonemal central apparatus gene, sperm-associated antigen 6, by a SRY-related high mobility group transcription factor, S-SOX5","volume":"285","author":"Kiselak","year":"2010","journal-title":"J. Biol. Chem"},{"issue":"4","key":"10.1016\/j.gene.2024.148199_b0105","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.cell.2007.02.005","article-title":"Chromatin modifications and their function","volume":"128","author":"Kouzarides","year":"2007","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.gene.2024.148199_b0110","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.molcel.2007.01.017","article-title":"Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase","volume":"25","author":"Kubicek","year":"2007","journal-title":"Mol. Cell"},{"issue":"41","key":"10.1016\/j.gene.2024.148199_b0115","doi-asserted-by":"crossref","first-page":"16021","DOI":"10.1073\/pnas.0806791105","article-title":"SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons","volume":"105","author":"Kwan","year":"2008","journal-title":"Proc. Natl. Acad. Sci. u.s.a."},{"issue":"12","key":"10.1016\/j.gene.2024.148199_b0120","doi-asserted-by":"crossref","first-page":"6786","DOI":"10.1093\/nar\/gkac533","article-title":"H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis","volume":"50","author":"Li","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"18","key":"10.1016\/j.gene.2024.148199_b0125","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1101\/gad.244848.114","article-title":"Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells","volume":"28","author":"Liu","year":"2014","journal-title":"Genes Dev."},{"issue":"6","key":"10.1016\/j.gene.2024.148199_b0130","first-page":"787","article-title":"SCAR-transformation of sex-specific SSR marker and its application in half-smooth tongue sole (Cynoglossus semiliaevis)","volume":"22","author":"Liu","year":"2014","journal-title":"J. Agric. Biotechnol."},{"key":"10.1016\/j.gene.2024.148199_b0135","article-title":"Single-Cell atlas of the Chinese tongue sole (Cynoglossus semiliaevis) ovary reveals transcriptional programs of oogenesis in Fish","volume":"10","author":"Liu","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"4","key":"10.1016\/j.gene.2024.148199_b0140","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.3390\/ijms24043761","article-title":"The role of the heat shock cognate protein 70 genes in sex determination and differentiation of Chinese tongue sole (Cynoglossus semiliaevis)","volume":"24","author":"Liu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"4","key":"10.1016\/j.gene.2024.148199_b0145","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"2","key":"10.1016\/j.gene.2024.148199_b0150","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1093\/nar\/gkx1052","article-title":"Dynamic reorganization of open chromatin underlies diverse transcriptomes during spermatogenesis","volume":"46","author":"Maezawa","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"10","key":"10.1016\/j.gene.2024.148199_b0155","doi-asserted-by":"crossref","first-page":"e107922","DOI":"10.1371\/journal.pone.0107922","article-title":"Cloning and characterization of tesk1, a novel spermatogenesis-related gene, in the tongue sole (Cynoglossus semilaevis)","volume":"9","author":"Meng","year":"2014","journal-title":"PLoS One"},{"issue":"23","key":"10.1016\/j.gene.2024.148199_b0160","doi-asserted-by":"crossref","first-page":"dev164160","DOI":"10.1242\/dev.164160","article-title":"SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling","volume":"145","author":"Mochizuki","year":"2018","journal-title":"Development"},{"issue":"12","key":"10.1016\/j.gene.2024.148199_b0165","doi-asserted-by":"crossref","first-page":"R510","DOI":"10.1016\/j.cub.2013.04.004","article-title":"Polygenic sex determination","volume":"23","author":"Moore","year":"2013","journal-title":"Curr. Biol."},{"issue":"3","key":"10.1016\/j.gene.2024.148199_b0170","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1152\/physrev.00044.2019","article-title":"Sex determination, gonadal sex differentiation, and plasticity in vertebrate species","volume":"101","author":"Nagahama","year":"2021","journal-title":"Physiol. Rev."},{"issue":"12","key":"10.1016\/j.gene.2024.148199_b0175","doi-asserted-by":"crossref","first-page":"e1002447","DOI":"10.1371\/journal.pgen.1002447","article-title":"DNA methylation of the gonadal aromatase (cyp19a) promoter is involved in temperature-dependent sex ratio shifts in the European Sea Bass","volume":"7","author":"Navarro-Mart\u00edn","year":"2011","journal-title":"PLoS Genet."},{"key":"10.1016\/j.gene.2024.148199_b0180","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/s41580-022-00483-w","article-title":"Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance","volume":"23","author":"Padeken","year":"2022","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"9796","key":"10.1016\/j.gene.2024.148199_b0185","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/35020506","article-title":"Regulation of chromatin structure by site-specific histone H3 methyltransferases","volume":"406","author":"Rea","year":"2000","journal-title":"Nature"},{"issue":"22","key":"10.1016\/j.gene.2024.148199_b0190","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1016\/j.devcel.2023.08.014","article-title":"A feedback loop between heterochromatin and the nucleopore complex controls germ-cell-to-oocyte transition during Drosophila oogenesis","volume":"58","author":"Sarkar","year":"2023","journal-title":"Dev Cell"},{"issue":"1","key":"10.1016\/j.gene.2024.148199_b0195","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12915-018-0485-8","article-title":"Sox5 is involved in germ-cell regulation and sex determination in medaka following co-option of nested transposable elements","volume":"16","author":"Schartl","year":"2018","journal-title":"BMC Biol."},{"issue":"8","key":"10.1016\/j.gene.2024.148199_b0200","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1101\/gad.973302","article-title":"SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins","volume":"16","author":"Schultz","year":"2002","journal-title":"Genes Dev."},{"issue":"4","key":"10.1016\/j.gene.2024.148199_b0205","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1101\/gr.162172.113","article-title":"Epigenetic modification and inheritance in sexual reversal of fish","volume":"24","author":"Shao","year":"2014","journal-title":"Genome Res."},{"issue":"1","key":"10.1016\/j.gene.2024.148199_b0210","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1038\/s41467-018-06697-x","article-title":"The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells","volume":"9","author":"Smolko","year":"2018","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.gene.2024.148199_b0215","doi-asserted-by":"crossref","first-page":"e1499","DOI":"10.1371\/journal.pone.0001499","article-title":"Genome-wide survey and developmental expression mapping of Zebrafish SET domain-containing genes","volume":"3","author":"Sun","year":"2008","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.gene.2024.148199_b0220","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1101\/gr.275962.121","article-title":"ceRNA crosstalk mediated by ncRNAs is a novel regulatory mechanism in fish sex determination and differentiation","volume":"32","author":"Tang","year":"2022","journal-title":"Genome Res."},{"issue":"8","key":"10.1016\/j.gene.2024.148199_b0225","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1101\/gr.247072.118","article-title":"Two contrasting classes of nucleolus-associated domains in mouse fibroblast heterochromatin","volume":"29","author":"Vertii","year":"2019","journal-title":"Genome Res."},{"issue":"2","key":"10.1016\/j.gene.2024.148199_b0230","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.molcel.2003.08.007","article-title":"mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression","volume":"12","author":"Wang","year":"2003","journal-title":"Mol. Cell"},{"issue":"4","key":"10.1016\/j.gene.2024.148199_b0235","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1007\/s00343-019-8182-1","article-title":"Functional analysis of the promoter of the dmrt1 gene in Chinese tongue sole, Cynoglossus Semilaevis","volume":"37","author":"Wang","year":"2019","journal-title":"J. Ocean. Limnol."},{"issue":"5","key":"10.1016\/j.gene.2024.148199_b0240","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s11427-021-2236-4","article-title":"Single-cell-resolution transcriptome map revealed novel genes involved in testicular germ cell progression and somatic cells specification in Chinese tongue sole with sex reversal","volume":"66","author":"Wang","year":"2023","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.gene.2024.148199_b0245","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cbpa.2018.05.016","article-title":"Leptin and leptin receptor genes in tongue sole (Cynoglossus semilaevis): Molecular cloning, tissue distribution and differential regulation of these genes by sex steroids","volume":"224","author":"Xu","year":"2018","journal-title":"Comp Biochem Physiol A Mol Integr Physiol"},{"issue":"1","key":"10.1016\/j.gene.2024.148199_b0250","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/sj.onc.1204998","article-title":"Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor","volume":"21","author":"Yang","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.gene.2024.148199_b0255","doi-asserted-by":"crossref","unstructured":"Zhang, Y., Zhang, S., Liu, Z., Zhang, L., Zhang, W., 2013. Epigenetic modifications during sex change repress gonadotropin stimulation of cyp19a1a in a teleost Ricefield Eel (Monopterus albus). Endocrinology 154 (8), 2881\u20132890. https:\/\/doi.org\/2020071613074412700.","DOI":"10.1210\/en.2012-2220"},{"issue":"6","key":"10.1016\/j.gene.2024.148199_b0260","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s11427-018-9346-6","article-title":"Characterization of H3 methylation in regulating oocyte development in cyprinid fish","volume":"62","author":"Zhou","year":"2019","journal-title":"Sci. China Life Sci."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111924000805?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111924000805?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,7]],"date-time":"2025-10-07T17:11:20Z","timestamp":1759857080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111924000805"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":52,"alternative-id":["S0378111924000805"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2024.148199","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular functional characterization of the setdb1 and its potential target gene sox5 illuminate the histone modification-mediated orchestration of gonadal development in Chinese tongue sole (Cynoglossus semilaevis)","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2024.148199","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"148199"}}