{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T21:05:44Z","timestamp":1794258344873,"version":"4.9.0"},"reference-count":78,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.gene.2024.148400","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T15:23:40Z","timestamp":1711466620000},"page":"148400","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Analysis of differentially expressed lncRNAs and mRNAs associated with slow\u2011transit constipation"],"prefix":"10.1016","volume":"914","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6888-9537","authenticated-orcid":false,"given":"Yuanxin","family":"Miao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongwei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonglian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxuan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhua","family":"Bi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Ai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2024.148400_b0005","doi-asserted-by":"crossref","DOI":"10.1172\/JCI165831","article-title":"Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B","author":"Azad","year":"2023","journal-title":"J. Clin. Invest."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0010","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1136\/gutjnl-2013-305965","article-title":"Increased colonic bile acid exposure: a relevant factor for symptoms and treatment in IBS","volume":"64","author":"Bajor","year":"2015","journal-title":"Gut"},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0015","first-page":"1189","article-title":"Abdominal cocoon as a presenting feature of systemic lupus erythematosus. A rare presentation","volume":"34","author":"Bansal","year":"2013","journal-title":"Saudi Med J."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0020","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S1590-8658(01)80133-X","article-title":"Low-amplitude propagated contractile waves: a relevant propulsive mechanism of human colon","volume":"33","author":"Bassotti","year":"2001","journal-title":"Digestive and Liver Disease: Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver."},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0025","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1016\/j.mayocp.2019.01.031","article-title":"Chronic constipation","volume":"94","author":"Bharucha","year":"2019","journal-title":"Mayo Clin. Proc."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0030","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1053\/j.gastro.2012.10.029","article-title":"American Gastroenterological Association medical position statement on constipation","volume":"144","author":"Bharucha","year":"2013","journal-title":"Gastroenterology"},{"issue":"2","key":"10.1016\/j.gene.2024.148400_b0035","doi-asserted-by":"crossref","first-page":"86","DOI":"10.5694\/mja18.00241","article-title":"Chronic idiopathic constipation in adults: epidemiology, pathophysiology, diagnosis and clinical management","volume":"209","author":"Black","year":"2018","journal-title":"Med. J. Aust."},{"issue":"5","key":"10.1016\/j.gene.2024.148400_b0040","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/hep.1840090518","article-title":"The liver and IgA: immunological, cell biological and clinical implications","volume":"9","author":"Brown","year":"1989","journal-title":"Hepatology"},{"key":"10.1016\/j.gene.2024.148400_b0045","doi-asserted-by":"crossref","first-page":"17095","DOI":"10.1038\/nrdp.2017.95","article-title":"Chronic constipation","volume":"3","author":"Camilleri","year":"2017","journal-title":"Nature Reviews Disease Primers."},{"issue":"10","key":"10.1016\/j.gene.2024.148400_b0050","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1080\/17474124.2018.1522248","article-title":"Elobixibat for the treatment of constipation","volume":"12","author":"Chedid","year":"2018","journal-title":"Expert Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.gene.2024.148400_b0055","first-page":"2951427","article-title":"Transcriptome analysis reveals the effect of long intergenic noncoding RNAs on pig muscle growth and fat deposition","volume":"2019","author":"Chen","year":"2019","journal-title":"Biomed Res. Int."},{"issue":"8","key":"10.1016\/j.gene.2024.148400_b0060","doi-asserted-by":"crossref","DOI":"10.3390\/genes11080868","article-title":"Identification of circRNA-lncRNA-miRNA-mRNA competitive endogenous RNA network as novel prognostic Markers for acute myeloid leukemia","volume":"11","author":"Cheng","year":"2020","journal-title":"Genes"},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0065","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1007\/BF02063253","article-title":"Nitric oxide synthase and VIP distribution in enteric nervous system in idiopathic chronic constipation","volume":"40","author":"Cortesini","year":"1995","journal-title":"Dig. Dis. Sci."},{"issue":"6","key":"10.1016\/j.gene.2024.148400_b0070","doi-asserted-by":"crossref","first-page":"13101","DOI":"10.1111\/nmo.13101","article-title":"Heterogeneity of enterochromaffin cells within the gastrointestinal tract","volume":"29","author":"Diwakarla","year":"2017","journal-title":"Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society."},{"issue":"16","key":"10.1016\/j.gene.2024.148400_b0075","first-page":"00223","article-title":"Functional gastrointestinal Disorders: history, pathophysiology","volume":"19","author":"Drossman","year":"2016","journal-title":"Clinical Features and Rome IV. Gastroenterology."},{"issue":"5","key":"10.1016\/j.gene.2024.148400_b0080","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/MCG.0000000000001333","article-title":"Disruption of circadian rhythms and gut motility: an overview of underlying mechanisms and associated pathologies","volume":"54","author":"Duboc","year":"2020","journal-title":"J. Clin. Gastroenterol."},{"issue":"4","key":"10.1016\/j.gene.2024.148400_b0085","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/ibd.20344","article-title":"Suppression of colon inflammation by CD80 blockade: evaluation in two murine models of inflammatory bowel disease","volume":"14","author":"Eri","year":"2008","journal-title":"Inflamm. Bowel Dis."},{"issue":"956528","key":"10.1016\/j.gene.2024.148400_b0090","article-title":"Abnormal bile acid metabolism is an important feature of gut microbiota and fecal metabolites in patients with slow transit constipation","volume":"12","author":"Fan","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0095","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/nrg3606","article-title":"Long non-coding RNAs: new players in cell differentiation and development","volume":"15","author":"Fatica","year":"2014","journal-title":"Nat. Rev. Genet."},{"issue":"13","key":"10.1016\/j.gene.2024.148400_b0100","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1177\/0961203316642308","article-title":"Gastrointestinal manifestations in systemic lupus erythematosus","volume":"25","author":"Fawzy","year":"2016","journal-title":"Lupus"},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0105","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.3748\/wjg.v21.i11.3174","article-title":"Nuclear factor kappa B role in inflammation associated gastrointestinal malignancies","volume":"21","author":"Gambhir","year":"2015","journal-title":"World J. Gastroenterol."},{"issue":"12","key":"10.1016\/j.gene.2024.148400_b0110","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.2174\/1389203718666170612104719","article-title":"Site-related effects of relaxin in the gastrointestinal Tract through nitric oxide signalling: an updated report","volume":"18","author":"Garella","year":"2017","journal-title":"Curr. Prot. Pept Sci."},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0115","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1089\/jir.2023.0097","article-title":"LINC00641\/miR-378a and their cross-talk with TNF-\u03b1\/IFN-\u03b3 as potential Biomarkers in ulcerative colitis and crohn's diseases","volume":"43","author":"Hameed","year":"2023","journal-title":"J Interferon Cytokine Res."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0120","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0016-5085(00)70409-4","article-title":"Decreased interstitial cell of cajal volume in patients with slow-transit constipation","volume":"118","author":"He","year":"2000","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0125","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang da","year":"2009","journal-title":"Nat. Protoc."},{"issue":"4","key":"10.1016\/j.gene.2024.148400_b0130","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.apsb.2015.05.006","article-title":"Current developments in pharmacological therapeutics for chronic constipation","volume":"5","author":"Jiang","year":"2015","journal-title":"Acta Pharm. Sin. B"},{"issue":"8","key":"10.1016\/j.gene.2024.148400_b0135","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1111\/j.1365-2982.2010.01524.x","article-title":"Substance P and vasoactive intestinal peptide are reduced in right transverse colon in pediatric slow-transit constipation","volume":"22","author":"King","year":"2010","journal-title":"Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0140","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bpg.2010.12.001","article-title":"Gastrointestinal neuromuscular pathology in chronic constipation","volume":"25","author":"Knowles","year":"2011","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"issue":"6","key":"10.1016\/j.gene.2024.148400_b0145","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1016\/0016-5085(91)90397-4","article-title":"Loss of interleukin-2-producing intestinal CD4+ T cells in inflammatory bowel disease","volume":"101","author":"Kusugami","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gene.2024.148400_b0150","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: an R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinf."},{"issue":"14","key":"10.1016\/j.gene.2024.148400_b0155","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1056\/NEJMra020995","article-title":"Chronic constipation","volume":"349","author":"Lembo","year":"2003","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.gene.2024.148400_b0160","doi-asserted-by":"crossref","first-page":"445","DOI":"10.7555\/JBR.31.20170026","article-title":"Generation of tryptophan hydroxylase 2 gene knockout pigs by CRISPR\/Cas9-mediated gene targeting","volume":"31","author":"Li","year":"2017","journal-title":"J. Biomed. Res."},{"key":"10.1016\/j.gene.2024.148400_b0165","doi-asserted-by":"crossref","first-page":"6506244","DOI":"10.1155\/2023\/6506244","article-title":"Xuanhuang runtong tablets relieve slow transit constipation in mice by regulating TLR5\/IL-17A signaling mediated by gut microbes","volume":"2023","author":"Liang","year":"2023","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0170","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1186\/s12967-021-02995-z","article-title":"Constipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL\/6 mice","volume":"19","author":"Lin","year":"2021","journal-title":"J. Transl. Med."},{"issue":"6","key":"10.1016\/j.gene.2024.148400_b0175","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1097\/MCG.0b013e31820fb914","article-title":"World gastroenterology organisation global guideline: constipation\u2013a global perspective","volume":"45","author":"Lindberg","year":"2011","journal-title":"J. Clin. Gastroenterol."},{"issue":"12","key":"10.1016\/j.gene.2024.148400_b0180","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1139\/cjpp-2021-0351","article-title":"Long non-coding RNA H19 acts as a microRNA-194 sponge to inhibit the apoptosis and promote the proliferation of hypertrophic scar fibroblasts","volume":"99","author":"Liu","year":"2021","journal-title":"Can J Physiol Pharmacol."},{"issue":"4","key":"10.1016\/j.gene.2024.148400_b0185","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.gene.2024.148400_b0190","doi-asserted-by":"crossref","unstructured":"Long Y, Huang Z, Deng Y, Chu H, Zheng X, Yang J, et al., 2017. Prevalence and risk factors for functional bowel disorders in South China: a population based study using the Rome III criteria. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 29(1).","DOI":"10.1111\/nmo.12897"},{"issue":"6","key":"10.1016\/j.gene.2024.148400_b0195","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/mi.2011.41","article-title":"Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut","volume":"4","author":"Mantis","year":"2011","journal-title":"Mucosal Immunol."},{"issue":"2","key":"10.1016\/j.gene.2024.148400_b0200","first-page":"309","article-title":"Alpha sinuclein expression in blood and its relationship with chronic constipation in a population from bogota, d.C., with problems of alcohol consumption","volume":"40","author":"Martinez-Rodriguez","year":"2020","journal-title":"Biomedica : Revista Del Instituto Nacional De Salud."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0205","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.genm.2009.04.007","article-title":"Gender differences in self-reported constipation characteristics, symptoms, and bowel and dietary habits among patients attending a specialty clinic for constipation","volume":"6","author":"McCrea","year":"2009","journal-title":"Gend. Med."},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0210","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1152\/ajpgi.00026.2016","article-title":"Importance of the alternative NF-\u03baB activation pathway in inflammation-associated gastrointestinal carcinogenesis","volume":"310","author":"Merga","year":"2016","journal-title":"Am J Physiol Gastrointest Liver Physiol."},{"issue":"4","key":"10.1016\/j.gene.2024.148400_b0215","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1177\/1756283X15578608","article-title":"Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunities","volume":"8","author":"Nelson","year":"2015","journal-title":"Therap. Adv. Gastroenterol."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0220","doi-asserted-by":"crossref","first-page":"021","DOI":"10.1186\/s41687-021-00321-1","article-title":"A qualitative study to explore symptoms and impacts of pediatric and adolescent crohn's disease from patient and caregiver perspective","volume":"5","author":"Newton","year":"2021","journal-title":"J Patient Rep Outcomes."},{"issue":"2","key":"10.1016\/j.gene.2024.148400_b0225","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1365-2982.2004.00507.x","article-title":"Oxytocin stimulates colonic motor activity in healthy women","volume":"16","author":"Ohlsson","year":"2004","journal-title":"Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0230","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1136\/gut.27.1.41","article-title":"Severe chronic constipation of young women: 'idiopathic slow transit constipation'","volume":"27","author":"Preston","year":"1986","journal-title":"Gut"},{"issue":"8","key":"10.1016\/j.gene.2024.148400_b0235","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/s41575-018-0021-x","article-title":"Mitochondrial function - gatekeeper of intestinal epithelial cell homeostasis","volume":"15","author":"Rath","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"4","key":"10.1016\/j.gene.2024.148400_b0240","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1096\/fj.14-259598","article-title":"Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells","volume":"29","author":"Reigstad","year":"2015","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0245","doi-asserted-by":"crossref","first-page":"123","DOI":"10.5056\/jnm18035","article-title":"Functional chronic constipation: Rome III criteria versus Rome IV criteria","volume":"25","author":"Russo","year":"2019","journal-title":"Journal of Neurogastroenterology and Motility."},{"issue":"3","key":"10.1016\/j.gene.2024.148400_b0250","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1007\/s10238-022-00853-w","article-title":"LncRNA H19 is a potential biomarker and correlated with immune infiltration in thyroid carcinoma","volume":"23","author":"Sahin","year":"2023","journal-title":"Clin Exp Med."},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0255","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S2468-1253(19)30199-2","article-title":"Chronic constipation: new insights, better outcomes?","volume":"4","author":"Schiller","year":"2019","journal-title":"Lancet Gastroenterol. Hepatol."},{"issue":"4","key":"10.1016\/j.gene.2024.148400_b0260","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ccell.2016.03.010","article-title":"Long noncoding RNAs in cancer pathways","volume":"29","author":"Schmitt","year":"2016","journal-title":"Cancer Cell"},{"issue":"962393","key":"10.1016\/j.gene.2024.148400_b0265","article-title":"Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosus","volume":"13","author":"Shen","year":"2022","journal-title":"Front Immunol."},{"issue":"1","key":"10.1016\/j.gene.2024.148400_b0270","doi-asserted-by":"crossref","first-page":"023","DOI":"10.1038\/s41598-023-47997-7","article-title":"Reduced LHFPL3-AS2 lncRNA expression is linked to altered epithelial polarity and proliferation, and to ileal ulceration in crohn disease","volume":"13","author":"Sosnovski","year":"2023","journal-title":"Sci. Rep."},{"issue":"6","key":"10.1016\/j.gene.2024.148400_b0275","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1093\/ecco-jcc\/jjad006","article-title":"GATA6-AS1 regulates intestinal epithelial mitochondrial functions, and its reduced expression is linked to intestinal inflammation and less favourable disease course in ulcerative colitis","volume":"17","author":"Sosnovski","year":"2023","journal-title":"J Crohns Colitis."},{"key":"10.1016\/j.gene.2024.148400_b0280","article-title":"Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts","volume":"41(17):e166-e","author":"Sun","year":"2013","journal-title":"Nucl. Acids Res."},{"issue":"12","key":"10.1016\/j.gene.2024.148400_b0285","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1097\/00042737-199612000-00014","article-title":"Decreased substance P levels in rectal biopsies from patients with slow transit constipation","volume":"8","author":"Tzavella","year":"1996","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.gene.2024.148400_b0290","doi-asserted-by":"crossref","unstructured":"Vedula S.V., Nickerson, T.P., Grider, D.J., 2021. A novel cause of bowel obstruction in a patient with long-standing Crohn's Disease: Case Rep. Pathol. 2021:3278392. doi: 10.1155\/2021\/3278392. eCollection 2021.","DOI":"10.1155\/2021\/3278392"},{"issue":"5","key":"10.1016\/j.gene.2024.148400_b0295","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1097\/MOP.0b013e32832ff241","article-title":"Recent advances in chronic constipation","volume":"21","author":"Walia","year":"2009","journal-title":"Curr. Opin. Pediatr."},{"issue":"11","key":"10.1016\/j.gene.2024.148400_b0300","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1038\/mp.2012.143","article-title":"A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53","volume":"18","author":"Wang","year":"2013","journal-title":"Mol Psychiatry."},{"issue":"12","key":"10.1016\/j.gene.2024.148400_b0305","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.1111\/nmo.12883","article-title":"Role of the nitrergic pathway in motor effects of oxytocin in rat proximal colon","volume":"28","author":"Wang","year":"2016","journal-title":"Neurogastroenterol. Motil. Off. J. Eur. Gastrointestinal Motility Soc."},{"issue":"3","key":"10.1016\/j.gene.2024.148400_b0310","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/apha.12890","article-title":"Inhibitory action of oxytocin on spontaneous contraction of rat distal colon by nitrergic mechanism: involvement of cyclic GMP and apamin-sensitive K(+) channels","volume":"221","author":"Wang","year":"2017","journal-title":"Acta Physiol (oxf)."},{"key":"10.1016\/j.gene.2024.148400_b0315","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.cca.2018.07.004","article-title":"LncRNA HOXA-AS2 and its molecular mechanisms in human cancer","volume":"485","author":"Wang","year":"2018","journal-title":"Clin. Chim. Acta; Int. J. Clin. Chem."},{"issue":"17","key":"10.1016\/j.gene.2024.148400_b0320","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/bioinformatics\/btz008","article-title":"Characterization and identification of long non-coding RNAs based on feature relationship","volume":"35","author":"Wang","year":"2019","journal-title":"Bioinformatics"},{"issue":"9","key":"10.1016\/j.gene.2024.148400_b0325","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.autrev.2015.05.004","article-title":"Emerging role of long noncoding RNAs in autoimmune diseases","volume":"14","author":"Wu","year":"2015","journal-title":"Autoimmun. Rev."},{"issue":"3","key":"10.1016\/j.gene.2024.148400_b0330","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.bbrc.2018.11.122","article-title":"Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway","volume":"508","author":"Xi","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.gene.2024.148400_b0335","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1365-201X.2005.01506.x","article-title":"The inhibitory effects of oxytocin on distal colonic contractile activity in rabbits are enhanced by ovarian steroids","volume":"186","author":"Xie","year":"2006","journal-title":"Acta Physiol (oxf)."},{"issue":"1\u20133","key":"10.1016\/j.gene.2024.148400_b0340","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.regpep.2011.08.003","article-title":"Exogenous oxytocin reverses the decrease of colonic smooth muscle contraction in antenatal maternal hypoxia mice via ganglia","volume":"172","author":"Xie","year":"2011","journal-title":"Regul. Pept."},{"issue":"6672899","key":"10.1016\/j.gene.2024.148400_b0345","article-title":"Comparative transcriptome analysis reveals relationship among mRNAs, lncRNAs, and circRNAs of slow transit constipation","volume":"23","author":"Yan","year":"2021","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.gene.2024.148400_b0350","doi-asserted-by":"crossref","first-page":"6672899","DOI":"10.1155\/2021\/6672899","article-title":"Comparative transcriptome analysis reveals relationship among mRNAs, lncRNAs, and circRNAs of slow transit constipation","volume":"2021","author":"Yan","year":"2021","journal-title":"Biomed Res. Int."},{"issue":"31","key":"10.1016\/j.gene.2024.148400_b0355","doi-asserted-by":"crossref","first-page":"10886","DOI":"10.3748\/wjg.v20.i31.10886","article-title":"Oxytocin decreases colonic motility of cold water stressed rats via oxytocin receptors","volume":"20","author":"Yang","year":"2014","journal-title":"World J. Gastroenterol."},{"issue":"5","key":"10.1016\/j.gene.2024.148400_b0360","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1159\/000373999","article-title":"Downregulation of lncRNA TUG1 affects apoptosis and insulin secretion in mouse pancreatic \u03b2 cells","volume":"35","author":"Yin","year":"2015","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.gene.2024.148400_b0365","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.semcdb.2014.05.015","article-title":"Functional interactions among microRNAs and long noncoding RNAs","volume":"34","author":"Yoon","year":"2014","journal-title":"Semin Cell Dev Biol."},{"key":"10.1016\/j.gene.2024.148400_b0370","doi-asserted-by":"crossref","first-page":"7569","DOI":"10.2147\/IJGM.S380208","article-title":"Analysis of key genes for slow transit constipation based on RNA sequencing","volume":"15","author":"Yu","year":"2022","journal-title":"Int. J. General Med."},{"issue":"6","key":"10.1016\/j.gene.2024.148400_b0375","doi-asserted-by":"crossref","first-page":"4696","DOI":"10.3892\/mmr.2020.11568","article-title":"Co-expression network analysis identified specific miRNAs and genes in association with slow-transit constipation","volume":"22","author":"Yu","year":"2020","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.gene.2024.148400_b0380","doi-asserted-by":"crossref","first-page":"6076293","DOI":"10.1155\/2021\/6076293","article-title":"Paeoniflorin improved constipation in the loperamide-induced rat model via TGR5\/TRPA1 signaling-mediated 5-hydroxytryptamine secretion","volume":"2021","author":"Zhan","year":"2021","journal-title":"Evidence-Based Complement. Alternat. Med.: Ecam."},{"key":"10.1016\/j.gene.2024.148400_b0385","article-title":"Long noncoding RNA AROD inhibits host antiviral innate immunity via the miR-324-5p-CUEDC2 Axis","volume":"e0420622","author":"Zhang","year":"2023","journal-title":"Microbiol. Spectrum"},{"key":"10.1016\/j.gene.2024.148400_b0390","doi-asserted-by":"crossref","first-page":"2617432","DOI":"10.1155\/2018\/2617432","article-title":"Aberrantly expressed genes and miRNAs in slow transit constipation based on RNA-seq analysis","volume":"2018","author":"Zhao","year":"2018","journal-title":"Biomed Res. Int."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111924002816?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111924002816?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T18:45:09Z","timestamp":1717267509000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111924002816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":78,"alternative-id":["S0378111924002816"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2024.148400","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of differentially expressed lncRNAs and mRNAs associated with slow\u2011transit constipation","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2024.148400","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"148400"}}