{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:23:37Z","timestamp":1787163817795,"version":"build-2736575974"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T00:00:00Z","timestamp":1722556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008908","name":"University of Messina","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008908","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.gene.2024.148806","type":"journal-article","created":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T18:16:35Z","timestamp":1722104195000},"page":"148806","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Involvement of selected circulating ncRNAs in the regulation of cognitive dysfunction induced by anesthesia"],"prefix":"10.1016","volume":"928","author":[{"given":"Adele","family":"Campo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Aliqu\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Velletri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Scuruchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Avenoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe Maurizio","family":"Campo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"D\u2019Ascola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Campo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"De Pasquale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gene.2024.148806_b0005","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3389\/fgene.2014.00158","article-title":"Transfer RNA and human disease","volume":"5","author":"Abbott","year":"2014","journal-title":"Front. Genet."},{"key":"10.1016\/j.gene.2024.148806_b0010","doi-asserted-by":"crossref","unstructured":"Assump\u00e7\u00e3o, C.B., Calcagno, D.Q., Ara\u00fajo, T.M., Santos, S.E., Santos \u00c2, K., Riggins, G.J., Burbano, R.R. and Assump\u00e7\u00e3o, P.P., 2015. The role of piRNA and its potential clinical implications in cancer. Epigenomics 7, 975\u2013984.","DOI":"10.2217\/epi.15.37"},{"key":"10.1016\/j.gene.2024.148806_b0015","doi-asserted-by":"crossref","first-page":"e1002264","DOI":"10.1371\/journal.pmed.1002264","article-title":"Association between delirium superimposed on dementia and mortality in hospitalized older adults: a prospective cohort study","volume":"14","author":"Avelino-Silva","year":"2017","journal-title":"PLoS Med."},{"key":"10.1016\/j.gene.2024.148806_b0020","article-title":"Long non-coding RNAs and their involvement in bipolar disorders","volume":"796\u2013797","author":"Bella","year":"2021","journal-title":"Gene"},{"key":"10.1016\/j.gene.2024.148806_b0025","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1111\/jgs.15770","article-title":"The INTUIT study: investigating neuroinflammation underlying postoperative cognitive dysfunction","volume":"67","author":"Berger","year":"2019","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.gene.2024.148806_b0030","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1080\/15476286.2022.2057725","article-title":"Mechanistic insights into non-coding Y RNA processing","volume":"19","author":"Billmeier","year":"2022","journal-title":"RNABiol"},{"key":"10.1016\/j.gene.2024.148806_b0035","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/10409238.2019.1608902","article-title":"Ro60 and Y RNAs: structure, functions, and roles in autoimmunity","volume":"54","author":"Boccitto","year":"2019","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/j.gene.2024.148806_b0040","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/nrn.2015.29","article-title":"Extracellular vesicles round off communication in the nervous system","volume":"17","author":"Budnik","year":"2016","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.gene.2024.148806_b0045","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1111\/jcmm.12904","article-title":"Long non-coding RNA Malat1 promotes neurite outgrowth through activation of ERK\/MAPK signalling pathway in N2a cells","volume":"20","author":"Chen","year":"2016","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.gene.2024.148806_b0050","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.1002\/jcb.27548","article-title":"BLACAT1 predicts poor prognosis and serves as oncogenic lncRNA in small-cell lung cancer","volume":"120","author":"Chen","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.gene.2024.148806_b0055","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s12031-018-1231-y","article-title":"miR-34a in Neurophysiology and Neuropathology","volume":"67","author":"Chua","year":"2019","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.gene.2024.148806_b0060","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.pneurobio.2017.01.005","article-title":"Anesthesia, brain changes, and behavior: Insights from neural systems biology","volume":"153","author":"Colon","year":"2017","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.gene.2024.148806_b0065","doi-asserted-by":"crossref","first-page":"3164","DOI":"10.3389\/fimmu.2018.03164","article-title":"Circulating Y-RNAs in extracellular vesicles and ribonucleoprotein complexes; implications for the immune system","volume":"9","author":"Driedonks","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.gene.2024.148806_b0070","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1097\/ALN.0000000000002956","article-title":"Perioperative Neurocognitive disorder: state of the preclinical science","volume":"132","author":"Eckenhoff","year":"2020","journal-title":"Anesthesiology"},{"key":"10.1016\/j.gene.2024.148806_b0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2013.07.035","article-title":"Effects of isoflurane or propofol on postnatal hippocampal neurogenesis in young and aged rats","volume":"1530","author":"Erasso","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.gene.2024.148806_b0080","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.bja.2017.11.087","article-title":"Recommendations for the nomenclature of cognitive change associated with anaesthesia and surgery-2018","volume":"121","author":"Evered","year":"2018","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.gene.2024.148806_b0085","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/s12264-012-1260-4","article-title":"Sevoflurane exposure in 7-day-old rats affects neurogenesis, neurodegeneration and neurocognitive function","volume":"28","author":"Fang","year":"2012","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.gene.2024.148806_b0090","doi-asserted-by":"crossref","first-page":"e12125","DOI":"10.1002\/trc2.12125","article-title":"Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults","volume":"7","author":"Fong","year":"2021","journal-title":"Alzheimers Dement (n y)"},{"key":"10.1016\/j.gene.2024.148806_b0095","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20201738","article-title":"Long non-coding RNA GAS5 aggravates myocardial depression in mice with sepsis via the microRNA-449b\/HMGB1 axis and the NF-\u03baB signaling pathway","volume":"41","author":"Gao","year":"2021","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.gene.2024.148806_b0100","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1007\/s11064-021-03249-6","article-title":"Downregulation of HOTAIR reduces neuronal pyroptosis by targeting miR-455-3p\/NLRP1 axis in propofol-treated neurons in vitro","volume":"46","author":"Gong","year":"2021","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.gene.2024.148806_b0105","doi-asserted-by":"crossref","unstructured":"Gul\u00eca, C., Signore, F., Gaffi, M., Gigli, S., Votino, R., Nucciotti, R., Bertacca, L., Zaami, S., Baffa, A., Santini, E., Porrello, A. and Piergentili, R., 2020. Y RNA: An Overview of Their Role as Potential Biomarkers and Molecular Targets in Human Cancers. Cancers (Basel) 12.","DOI":"10.3390\/cancers12051238"},{"key":"10.1016\/j.gene.2024.148806_b0110","first-page":"1138","article-title":"Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells","volume":"1","author":"Hendrick","year":"1981","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.gene.2024.148806_b0115","doi-asserted-by":"crossref","first-page":"e2530","DOI":"10.1038\/cddis.2016.429","article-title":"RNY (YRNA)-derived small RNAs regulate cell death and inflammation in monocytes\/macrophages","volume":"8","author":"Hizir","year":"2017","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.gene.2024.148806_b0120","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1186\/1471-2164-14-319","article-title":"Characterization of human plasma-derived exosomal RNAs by deep sequencing","volume":"14","author":"Huang","year":"2013","journal-title":"BMC Genomics"},{"key":"10.1016\/j.gene.2024.148806_b0125","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1097\/ALN.0b013e3182815948","article-title":"Propofol anesthesia impairs the maturation and survival of adult-born hippocampal neurons","volume":"118","author":"Krzisch","year":"2013","journal-title":"Anesthesiology"},{"key":"10.1016\/j.gene.2024.148806_b0130","first-page":"13452","article-title":"miR-34a overexpression protects against hippocampal neuron damage caused by ketamine-induced anesthesia in immature rats through the Notch-1\/NF-\u03baB signaling pathway","volume":"13","author":"Li","year":"2021","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.gene.2024.148806_b0135","first-page":"47","article-title":"Prognostic value of long non-coding RNA BLACAT1 in patients with papillary thyroid carcinoma","volume":"18","author":"Liao","year":"2018","journal-title":"Cancer CellInt"},{"key":"10.1016\/j.gene.2024.148806_b0140","doi-asserted-by":"crossref","first-page":"240","DOI":"10.3389\/fnmol.2019.00240","article-title":"Role of exosomes in central nervous system diseases","volume":"12","author":"Liu","year":"2019","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.gene.2024.148806_b0150","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/jnc.14208","article-title":"MicroRNA-27a-3p suppression of peroxisome proliferator-activated receptor-\u03b3 contributes to cognitive impairments resulting from sevoflurane treatment","volume":"143","author":"Lv","year":"2017","journal-title":"J. Neurochem."},{"key":"10.1016\/j.gene.2024.148806_b0155","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.tcb.2016.11.003","article-title":"Extracellular vesicles: unique intercellular delivery vehicles","volume":"27","author":"Maas","year":"2017","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.gene.2024.148806_b0160","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1053\/j.trap.2008.09.002","article-title":"Regional anesthesia and patient outcomes: evidence-based medicine","volume":"12","author":"Mathur","year":"2008","journal-title":"Techniques in Regional Anesthesia and Pain Management"},{"key":"10.1016\/j.gene.2024.148806_b0165","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1213\/01.ane.0000255729.96438.b0","article-title":"Use of anesthetic agents in neonates and young children","volume":"104","author":"Mellon","year":"2007","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.gene.2024.148806_b0170","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.brainres.2006.11.035","article-title":"RT-PCR-based analysis of microRNA (miR-1 and -124) expression in mouse CNS","volume":"1131","author":"Mishima","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.gene.2024.148806_b0175","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s11701-024-01861-6","article-title":"Biochemical implications of robotic surgery: a new frontier in the operating room","volume":"18","author":"Mokhtari","year":"2024","journal-title":"J. Robot. Surg."},{"key":"10.1016\/j.gene.2024.148806_b0180","doi-asserted-by":"crossref","first-page":"i115","DOI":"10.1093\/bja\/aex354","article-title":"Postoperative cognitive dysfunction and dementia: what we need to know and do","volume":"119","author":"Needham","year":"2017","journal-title":"Br. J. Anaesth."},{"key":"10.1016\/j.gene.2024.148806_b0185","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/ALN.0000000000000969","article-title":"Emerging roles for MicroRNAs in perioperative medicine","volume":"124","author":"Neudecker","year":"2016","journal-title":"Anesthesiology"},{"key":"10.1016\/j.gene.2024.148806_b0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2019.172737","article-title":"Inhibition of long noncoding RNA BLACAT1 protects anesthesia-induced neural cytotoxicity in human induced pluripotent stem cells derived neurons","volume":"865","author":"Niu","year":"2019","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.gene.2024.148806_b0195","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1097\/ALN.0000000000002562","article-title":"GABAA Receptor Theory of Perioperative Neurocognitive Disorders","volume":"130","author":"Orser","year":"2019","journal-title":"Anesthesiology"},{"key":"10.1016\/j.gene.2024.148806_b0200","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-981-13-1426-1_6","article-title":"Circular RNAs Act as miRNA Sponges","volume":"1087","author":"Panda","year":"2018","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.gene.2024.148806_b0205","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1213\/ANE.0000000000005317","article-title":"Emerging Role of Long Noncoding RNAs in Perioperative Neurocognitive Disorders and Anesthetic-Induced Developmental Neurotoxicity","volume":"132","author":"Pant","year":"2021","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.gene.2024.148806_b0210","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1213\/ANE.0b013e3182147f6d","article-title":"Review articles: postoperative delirium: acute change with long-term implications","volume":"112","author":"Rudolph","year":"2011","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.gene.2024.148806_b0215","doi-asserted-by":"crossref","first-page":"5451","DOI":"10.1002\/jcp.27486","article-title":"An overview of microRNAs: Biology, functions, therapeutics, and analysis methods","volume":"234","author":"Saliminejad","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.gene.2024.148806_b0220","first-page":"627","article-title":"Noncoding RNAs in neurodegeneration","volume":"18","author":"Salta","year":"2017","journal-title":"Nature ReviewsNeurosci"},{"key":"10.1016\/j.gene.2024.148806_b0225","doi-asserted-by":"crossref","first-page":"623","DOI":"10.2146\/ajhp050460","article-title":"Inhaled anesthetic agents","volume":"63","author":"Stachnik","year":"2006","journal-title":"American Journal of HealthSyst Pharm"},{"key":"10.1016\/j.gene.2024.148806_b0230","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/s41580-020-00315-9","article-title":"Gene regulation by long non-coding RNAs and its biological functions","volume":"22","author":"Statello","year":"2021","journal-title":"Nature ReviewsMol Cell Biol"},{"key":"10.1016\/j.gene.2024.148806_b0235","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.cell.2005.03.009","article-title":"Structural insights into RNA quality control: the Ro autoantigen binds misfolded RNAs via its central cavity","volume":"121","author":"Stein","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.gene.2024.148806_b0240","doi-asserted-by":"crossref","first-page":"26760","DOI":"10.3402\/jev.v4.26760","article-title":"Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting","volume":"4","author":"van Balkom","year":"2015","journal-title":"J Extracell Vesicles"},{"key":"10.1016\/j.gene.2024.148806_b0245","doi-asserted-by":"crossref","first-page":"e7566","DOI":"10.1590\/1414-431x20187566","article-title":"Role of non-coding RNAs in non-aging-related neurological disorders","volume":"51","author":"Vieira","year":"2018","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.gene.2024.148806_b0250","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.4240\/wjgs.v16.i6.1734","article-title":"Influence of reduced-port laparoscopic surgery on perioperative indicators, postoperative recovery, and serum inflammation in patients with colorectal carcinoma","volume":"16","author":"Wu","year":"2024","journal-title":"World J Gastrointest Surg"},{"key":"10.1016\/j.gene.2024.148806_b0255","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.brainresbull.2018.09.001","article-title":"MicroRNA-96 is responsible for sevoflurane-induced cognitive dysfunction in neonatal rats via inhibiting IGF1R","volume":"144","author":"Xu","year":"2019","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.gene.2024.148806_b0260","doi-asserted-by":"crossref","first-page":"1024475","DOI":"10.3389\/fncel.2022.1024475","article-title":"Recent progress on the role of non-coding RNA in postoperative cognitive dysfunction","volume":"16","author":"Yang","year":"2022","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.gene.2024.148806_b0265","doi-asserted-by":"crossref","first-page":"8263","DOI":"10.2147\/OTT.S261461","article-title":"Long Non-Coding RNA BLACAT1 in Human Cancers","volume":"13","author":"Ye","year":"2020","journal-title":"Onco Targets Ther"},{"key":"10.1016\/j.gene.2024.148806_b0270","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.18632\/aging.101528","article-title":"The long non-coding RNA FLJ46906 binds to the transcription factors NF-\u03baB and AP-1 and regulates expression of aging-associated genes","volume":"10","author":"Yo","year":"2018","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.gene.2024.148806_b0275","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ntt.2016.12.004","article-title":"A holistic approach to anesthesia-induced neurotoxicity and its implications for future mechanistic studies","volume":"60","author":"Zanghi","year":"2017","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.gene.2024.148806_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2019.116606","article-title":"Knockdown of lncRNA MALAT1 alleviates bupivacaine-induced neurotoxicity via the miR-101-3p\/PDCD4 axis","volume":"232","author":"Zhao","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.gene.2024.148806_b0285","doi-asserted-by":"crossref","first-page":"701","DOI":"10.17219\/acem\/134740","article-title":"MiR-124 protects against cognitive dysfunction induced by sevoflurane anesthesia in vivo and in vitro through targeting calpain small subunit 1 via NF-\u03baB signaling pathway","volume":"30","author":"Zhao","year":"2021","journal-title":"Adv. Clin. Exp. Med."},{"key":"10.1016\/j.gene.2024.148806_b0290","first-page":"3049","article-title":"GAS5-mediated regulation of cell signaling (Review)","volume":"22","author":"Zhou","year":"2020","journal-title":"Mol. Med. Rep."}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111924006875?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111924006875?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T17:29:50Z","timestamp":1736357390000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111924006875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":57,"alternative-id":["S0378111924006875"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2024.148806","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Involvement of selected circulating ncRNAs in the regulation of cognitive dysfunction induced by anesthesia","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2024.148806","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"148806"}}