{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T19:38:41Z","timestamp":1769024321721,"version":"3.49.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Shandong Province Natural Science Foundation","doi-asserted-by":"publisher","award":["ZR2019BC065"],"award-info":[{"award-number":["ZR2019BC065"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.gene.2025.149978","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:11:11Z","timestamp":1766535071000},"page":"149978","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["PRDM14 promotes the bovine somatic stem cell reprogramming through enhancing oxidative phosphorylation at the initial stage"],"prefix":"10.1016","volume":"982","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6953-0013","authenticated-orcid":false,"given":"Qingqing","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guina","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiliang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaorong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.gene.2025.149978_b0005","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.stemcr.2014.04.001","article-title":"Temporal perturbation of the Wnt signaling pathway in the control of cell reprogramming is modulated by TCF1","volume":"2","author":"Aulicino","year":"2014","journal-title":"Stem Cell Rep."},{"issue":"2","key":"10.1016\/j.gene.2025.149978_b0010","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/jpi.12334","article-title":"Melatonin improves reprogramming efficiency and proliferation of bovine-induced pluripotent stem cells","volume":"61","author":"Bai","year":"2016","journal-title":"J. Pineal Res."},{"issue":"6","key":"10.1016\/j.gene.2025.149978_b0015","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.3390\/cells10061531","article-title":"Cattle In Vitro Induced Pluripotent Stem Cells Generated and Maintained in 5 or 20% Oxygen and Different Supplementation","volume":"10","author":"Bessi","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.gene.2025.149978_b0020","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.938709","article-title":"Acquisition and maintenance of pluripotency are influenced by fibroblast growth factor, leukemia inhibitory factor, and 2i in bovine-induced pluripotent stem cells","volume":"10","author":"Botigelli","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0025","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1186\/s13287-020-01716-5","article-title":"Generation of induced pluripotent stem cells from large domestic animals","volume":"11","author":"Bressan","year":"2020","journal-title":"Stem Cell Res. Ther."},{"issue":"7150","key":"10.1016\/j.gene.2025.149978_b0030","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/nature05950","article-title":"Derivation of pluripotent epiblast stem cells from mammalian embryos","volume":"448","author":"Brons","year":"2007","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0035","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1186\/s13104-018-3627-8","article-title":"Exogenous human OKSM factors maintain pluripotency gene expression of bovine and porcine iPS-like cells obtained with STEMCCA delivery system","volume":"11","author":"Canizo","year":"2018","journal-title":"BMC. Res. Notes"},{"issue":"3","key":"10.1016\/j.gene.2025.149978_b0040","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/sj.ejhg.5201535","article-title":"Large animal models and gene therapy","volume":"14","author":"Casal","year":"2006","journal-title":"Eur. J. Hum. Genet."},{"issue":"4","key":"10.1016\/j.gene.2025.149978_b0045","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1002\/stem.1307","article-title":"A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming","volume":"31","author":"Chan","year":"2013","journal-title":"Stem Cells"},{"issue":"7321","key":"10.1016\/j.gene.2025.149978_b0050","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/nature09531","article-title":"A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity","volume":"468","author":"Chia","year":"2010","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.gene.2025.149978_b0055","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1089\/cell.2014.0087","article-title":"Generation of induced pluripotent stem cells from bovine epithelial cells and partial redirection toward a mammary phenotype in vitro","volume":"17","author":"Cravero","year":"2015","journal-title":"Cell. Reprogram."},{"issue":"2","key":"10.1016\/j.gene.2025.149978_b0060","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.cmet.2011.06.011","article-title":"Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming","volume":"14","author":"Folmes","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.gene.2025.149978_b0065","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.canlet.2019.10.029","article-title":"SIK2 promotes reprogramming of glucose metabolism through PI3K\/AKT\/HIF-1\u03b1 pathway and Drp1-mediated mitochondrial fission in ovarian cancer","volume":"469","author":"Gao","year":"2020","journal-title":"Cancer Lett."},{"issue":"6","key":"10.1016\/j.gene.2025.149978_b0070","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/s41556-019-0333-2","article-title":"Establishment of porcine and human expanded potential stem cells","volume":"21","author":"Gao","year":"2019","journal-title":"Nat. Cell Biol."},{"issue":"6118","key":"10.1016\/j.gene.2025.149978_b0075","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1126\/science.1229277","article-title":"Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine","volume":"339","author":"Hackett","year":"2013","journal-title":"Science"},{"issue":"10","key":"10.1016\/j.gene.2025.149978_b0080","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1038\/cr.2011.125","article-title":"Generation of induced pluripotent stem cells from bovine embryonic fibroblast cells","volume":"21","author":"Han","year":"2011","journal-title":"Cell Res."},{"issue":"8","key":"10.1016\/j.gene.2025.149978_b0085","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1016\/j.celrep.2016.02.003","article-title":"NRF2 orchestrates the metabolic shift during induced pluripotent stem cell reprogramming","volume":"14","author":"Hawkins","year":"2016","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.gene.2025.149978_b0090","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1089\/scd.2014.0278","article-title":"CRISPR\/Cas9 nuclease-mediated gene knock-in in bovine-induced pluripotent cells","volume":"24","author":"Heo","year":"2015","journal-title":"Stem Cells Dev."},{"issue":"6146","key":"10.1016\/j.gene.2025.149978_b0095","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1126\/science.1239278","article-title":"Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds","volume":"341","author":"Hou","year":"2013","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.gene.2025.149978_b0100","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/nchembio.1552","article-title":"Notch inhibition allows oncogene-independent generation of iPS cells","volume":"10","author":"Ichida","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.gene.2025.149978_b0105","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.theriogenology.2019.11.022","article-title":"Transcriptome profile of bovine iPSCs derived from Sertoli cells","volume":"146","author":"Jiang","year":"2020","journal-title":"Theriogenology"},{"issue":"8","key":"10.1016\/j.gene.2025.149978_b0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0135403","article-title":"Generation of na\u00efve bovine induced pluripotent stem cells using PiggyBac transposition of doxycycline-inducible transcription factors","volume":"10","author":"Kawaguchi","year":"2015","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.gene.2025.149978_b0115","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.stem.2015.03.001","article-title":"ERRs mediate a metabolic switch required for somatic cell reprogramming to pluripotency","volume":"16","author":"Kida","year":"2015","journal-title":"Cell Stem Cell"},{"issue":"3","key":"10.1016\/j.gene.2025.149978_b0120","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/nsmb.2510","article-title":"Naive pluripotency is associated with global DNA hypomethylation","volume":"20","author":"Leitch","year":"2013","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0125","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.stem.2010.04.014","article-title":"A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts","volume":"7","author":"Li","year":"2010","journal-title":"Cell Stem Cell"},{"issue":"11","key":"10.1016\/j.gene.2025.149978_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.105293","article-title":"Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity","volume":"25","author":"Li","year":"2022","journal-title":"iScience"},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0135","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13287-018-0792-6","article-title":"Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C","volume":"9","author":"Lin","year":"2018","journal-title":"Stem Cell Res. Ther."},{"issue":"4","key":"10.1016\/j.gene.2025.149978_b0140","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.bbrc.2012.12.148","article-title":"Mitochondrial metabolism transition cooperates with nuclear reprogramming during induced pluripotent stem cell generation","volume":"431","author":"Liu","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"5","key":"10.1016\/j.gene.2025.149978_b0145","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.stem.2014.02.012","article-title":"Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency","volume":"14","author":"Mathieu","year":"2014","journal-title":"Cell Stem Cell"},{"issue":"6","key":"10.1016\/j.gene.2025.149978_b0150","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.tibs.2014.04.003","article-title":"PRDM14: a unique regulator for pluripotency and epigenetic reprogramming","volume":"39","author":"Nakaki","year":"2014","journal-title":"Trends Biochem. Sci."},{"issue":"7618","key":"10.1016\/j.gene.2025.149978_b0155","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature19096","article-title":"A developmental coordinate of pluripotency among mice, monkeys and humans","volume":"537","author":"Nakamura","year":"2016","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.gene.2025.149978_b0160","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1242\/dev.099622","article-title":"PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells","volume":"141","author":"Okashita","year":"2014","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0165","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/cr.2011.177","article-title":"The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming","volume":"22","author":"Panopoulos","year":"2012","journal-title":"Cell Res."},{"issue":"6","key":"10.1016\/j.gene.2025.149978_b0170","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.stemcr.2018.10.018","article-title":"MYC induces a hybrid energetics program early in cell reprogramming","volume":"11","author":"Prieto","year":"2018","journal-title":"Stem Cell Rep."},{"issue":"4","key":"10.1016\/j.gene.2025.149978_b0175","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/stem.404","article-title":"The senescence-related mitochondrial\/oxidative stress pathway is repressed in human induced pluripotent stem cells","volume":"28","author":"Prigione","year":"2010","journal-title":"Stem Cells"},{"issue":"2","key":"10.1016\/j.gene.2025.149978_b0180","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1002\/stem.1552","article-title":"HIF1alpha modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2","volume":"32","author":"Prigione","year":"2014","journal-title":"Stem Cells"},{"issue":"9","key":"10.1016\/j.gene.2025.149978_b0185","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1093\/hmg\/dds023","article-title":"Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming","volume":"21","author":"Qin","year":"2012","journal-title":"Hum. Mol. Genet."},{"issue":"48","key":"10.1016\/j.gene.2025.149978_b0190","doi-asserted-by":"crossref","first-page":"84276","DOI":"10.18632\/oncotarget.20685","article-title":"Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs","volume":"8","author":"Qin","year":"2017","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0195","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1186\/s13287-021-02578-1","article-title":"AKT signaling is associated with epigenetic reprogramming via the upregulation of TET and its cofactor, alpha-ketoglutarate during iPSC generation","volume":"12","author":"Sekita","year":"2021","journal-title":"Stem Cell Res. Ther."},{"issue":"5","key":"10.1016\/j.gene.2025.149978_b0200","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.stemcr.2017.04.001","article-title":"2i maintains a naive ground state in ESCs through two distinct epigenetic mechanisms","volume":"8","author":"Sim","year":"2017","journal-title":"Stem Cell Rep."},{"issue":"11","key":"10.1016\/j.gene.2025.149978_b0205","doi-asserted-by":"crossref","DOI":"10.1093\/jas\/skaa343","article-title":"Induced pluripotent stem cells from farm animals","volume":"98","author":"Su","year":"2020","journal-title":"J. Anim. Sci."},{"issue":"4","key":"10.1016\/j.gene.2025.149978_b0210","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.cell.2006.07.024","article-title":"Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors","volume":"126","author":"Takahashi","year":"2006","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.gene.2025.149978_b0215","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1089\/cell.2014.0080","article-title":"Derivation and characterization of bovine induced pluripotent stem cells by transposon-mediated reprogramming","volume":"17","author":"Talluri","year":"2015","journal-title":"Cell. Reprogram."},{"issue":"7150","key":"10.1016\/j.gene.2025.149978_b0220","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/nature05972","article-title":"New cell lines from mouse epiblast share defining features with human embryonic stem cells","volume":"448","author":"Tesar","year":"2007","journal-title":"Nature"},{"issue":"Suppl 2","key":"10.1016\/j.gene.2025.149978_b0225","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s11248-019-00141-6","article-title":"Application of genome editing in farm animals: cattle","volume":"28","author":"Van Eenennaam","year":"2019","journal-title":"Transgenic Res."},{"issue":"6","key":"10.1016\/j.gene.2025.149978_b0230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0020914","article-title":"Energy metabolism in human pluripotent stem cells and their differentiated counterparts","volume":"6","author":"Varum","year":"2011","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.gene.2025.149978_b0235","doi-asserted-by":"crossref","first-page":"e907","DOI":"10.1038\/cddis.2013.420","article-title":"Androgen receptor-mediated apoptosis in bovine testicular induced pluripotent stem cells in response to phthalate esters","volume":"4","author":"Wang","year":"2013","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0240","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/biolre\/iox071","article-title":"Bovine lineage specification revealed by single-cell gene expression analysis from zygote to blastocyst","volume":"97","author":"Wei","year":"2017","journal-title":"Biol. Reprod."},{"issue":"14","key":"10.1016\/j.gene.2025.149978_b0245","doi-asserted-by":"crossref","first-page":"4394","DOI":"10.1111\/febs.15744","article-title":"LCDM medium supports the derivation of bovine extended pluripotent stem cells with embryonic and extraembryonic potency in bovine-mouse chimeras from iPSCs and bovine fetal fibroblasts","volume":"288","author":"Xiang","year":"2021","journal-title":"FEBS J."},{"issue":"1","key":"10.1016\/j.gene.2025.149978_b0250","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1186\/s13287-019-1303-0","article-title":"Generation of pig induced pluripotent stem cells using an extended pluripotent stem cell culture system","volume":"10","author":"Xu","year":"2019","journal-title":"Stem Cell Res. Ther."},{"issue":"8","key":"10.1016\/j.gene.2025.149978_b0255","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1038\/ng.186","article-title":"Critical function of Prdm14 for the establishment of the germ cell lineage in mice","volume":"40","author":"Yamaji","year":"2008","journal-title":"Nat. Genet."},{"issue":"3","key":"10.1016\/j.gene.2025.149978_b0260","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.stem.2012.12.012","article-title":"PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells","volume":"12","author":"Yamaji","year":"2013","journal-title":"Cell Stem Cell"},{"issue":"2","key":"10.1016\/j.gene.2025.149978_b0265","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.cell.2017.02.005","article-title":"Derivation of pluripotent stem cells with in vivo embryonic and extraembryonic potency","volume":"169","author":"Yang","year":"2017","journal-title":"Cell"},{"issue":"7194","key":"10.1016\/j.gene.2025.149978_b0270","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nature06968","article-title":"The ground state of embryonic stem cell self-renewal","volume":"453","author":"Ying","year":"2008","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.gene.2025.149978_b0275","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.stem.2009.08.001","article-title":"Hypoxia enhances the generation of induced pluripotent stem cells","volume":"5","author":"Yoshida","year":"2009","journal-title":"Cell Stem Cell"},{"issue":"15","key":"10.1016\/j.gene.2025.149978_b0280","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2018505118","article-title":"Establishment of bovine expanded potential stem cells","volume":"118","author":"Zhao","year":"2021","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"5","key":"10.1016\/j.gene.2025.149978_b0285","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.tice.2017.05.005","article-title":"Characterization of the single-cell derived bovine induced pluripotent stem cells","volume":"49","author":"Zhao","year":"2017","journal-title":"Tissue Cell"}],"container-title":["Gene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111925007681?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0378111925007681?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T04:27:16Z","timestamp":1768969636000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0378111925007681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":57,"alternative-id":["S0378111925007681"],"URL":"https:\/\/doi.org\/10.1016\/j.gene.2025.149978","relation":{},"ISSN":["0378-1119"],"issn-type":[{"value":"0378-1119","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PRDM14 promotes the bovine somatic stem cell reprogramming through enhancing oxidative phosphorylation at the initial stage","name":"articletitle","label":"Article Title"},{"value":"Gene","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gene.2025.149978","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"149978"}}