{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T03:26:33Z","timestamp":1778901993509,"version":"3.51.4"},"reference-count":17,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["ghpjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["General Hospital Psychiatry"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.genhosppsych.2014.10.008","type":"journal-article","created":{"date-parts":[[2014,10,25]],"date-time":"2014-10-25T02:02:17Z","timestamp":1414202537000},"page":"49-52","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["The effect of penicillin therapy on cognitive outcomes in neurosyphilis: a systematic review of the literature"],"prefix":"10.1016","volume":"37","author":[{"given":"Calum D.","family":"Moulton","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Koychev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.genhosppsych.2014.10.008_bb0005","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0163-8343(95)00030-U","article-title":"Cognitive change after treatment for neurosyphilis. Correlation with CSF laboratory measures","volume":"17","author":"Roberts","year":"1995","journal-title":"Gen Hosp Psychiatry"},{"issue":"5","key":"10.1016\/j.genhosppsych.2014.10.008_bb0010","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1001\/archneurpsyc.1959.02340170023003","article-title":"Penicillin treatment of general paresis (dementia paralytica)","volume":"81","author":"Hahn","year":"1959","journal-title":"AMA Arch Neurol Psychiatry"},{"issue":"4","key":"10.1016\/j.genhosppsych.2014.10.008_bb0015","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/01.olq.0000149848.03733.c1","article-title":"The re-emergence of syphilis in the United Kingdom: the new epidemic phases","volume":"32","author":"Simms","year":"2005","journal-title":"Sex Transm Dis"},{"issue":"2","key":"10.1016\/j.genhosppsych.2014.10.008_bb0020","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1136\/jnnp.59.2.194","article-title":"Ceftriaxone treatment of penicillin-resistance neurosyphilis in alcoholic patients","volume":"59","author":"Cnossen","year":"1995","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"Suppl. 2","key":"10.1016\/j.genhosppsych.2014.10.008_bb0025","first-page":"S24","article-title":"Neurosyphilis in differential diagnosis of subacute dementia: report of a case","volume":"41","author":"Ferrari","year":"2014","journal-title":"J Alzheimers Dis"},{"issue":"2","key":"10.1016\/j.genhosppsych.2014.10.008_bb0030","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/NRL.0b013e31817781c9","article-title":"Initially unrecognized dementia in a young man with neurosyphilis","volume":"15","author":"Lee","year":"2009","journal-title":"Neurologist"},{"key":"10.1016\/j.genhosppsych.2014.10.008_bb0035","doi-asserted-by":"crossref","first-page":"8334","DOI":"10.4076\/1757-1626-2-8334","article-title":"Neurosyphilis presenting with dementia, chronic chorioretinitis and adverse reactions to treatment: a case report","volume":"2","author":"Mehrabian","year":"2009","journal-title":"Cases J"},{"key":"10.1016\/j.genhosppsych.2014.10.008_bb0040","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/1471-2377-12-96","article-title":"Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging","volume":"12","author":"Mehrabian","year":"2012","journal-title":"BMC Neurol"},{"issue":"4","key":"10.1016\/j.genhosppsych.2014.10.008_bb0045","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1601-5215.2007.00209.x","article-title":"Neurosyphilis presenting as psychiatric symptoms: an unusual case report","volume":"19","author":"Mirsal","year":"2007","journal-title":"Acta Neuropsychiatr"},{"issue":"4","key":"10.1016\/j.genhosppsych.2014.10.008_bb0050","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/13554799708405011","article-title":"A neuropsychological and neuroimaging study of a patient before and after treatment for paretic neurosyphilis","volume":"3","author":"Mimura","year":"1997","journal-title":"Neurocase"},{"issue":"11","key":"10.1016\/j.genhosppsych.2014.10.008_bb0055","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1007\/s10072-013-1531-5","article-title":"Neurosyphilis manifesting with rapidly progressive dementia: report of three cases","volume":"34","author":"Stefani","year":"2013","journal-title":"Neurol Sci"},{"issue":"2","key":"10.1016\/j.genhosppsych.2014.10.008_bb0060","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1016\/S0140-6736(68)92674-3","article-title":"Prognosis of general paresis after treatment","volume":"7582","author":"Wilner","year":"1968","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.genhosppsych.2014.10.008_bb0065","first-page":"371","article-title":"Penicillin concentrations in serum and cerebrospinal fluid after intramuscular injection of aqueous procaine penicillin 0.6 MU with and without probenecid","volume":"60","author":"Goh","year":"1984","journal-title":"Br J Vener Dis"},{"issue":"Suppl. 2","key":"10.1016\/j.genhosppsych.2014.10.008_bb0070","doi-asserted-by":"crossref","first-page":"S314","DOI":"10.1093\/clinids\/7-Supplement_2.S314","article-title":"Potential for development of antibiotic resistance in pathogenic treponemes","volume":"7","author":"Stapleton","year":"1985","journal-title":"Rev Infect Dis"},{"key":"10.1016\/j.genhosppsych.2014.10.008_bb0075","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3348\/kjr.2009.10.3.310","article-title":"MRI of neurosyphilis presenting as mesiotemporal abnormalities: a case report","volume":"10","author":"Jeong","year":"2009","journal-title":"Korean J Radiol"},{"issue":"4","key":"10.1016\/j.genhosppsych.2014.10.008_bb0080","doi-asserted-by":"crossref","first-page":"E41","DOI":"10.1176\/jnp.23.4.jnpe41","article-title":"Neurosyphilis as a cause of cognitive decline and psychiatric symptoms at younger age","volume":"23","author":"Keskin","year":"2011","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.genhosppsych.2014.10.008_bb0085","doi-asserted-by":"crossref","first-page":"368","DOI":"10.7326\/0003-4819-104-3-368","article-title":"Syphilis tests in diagnostic and therapeutic decision making","volume":"104","author":"Hart","year":"1986","journal-title":"Ann Intern Med"}],"container-title":["General Hospital Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163834314002801?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163834314002801?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,28]],"date-time":"2018-09-28T03:24:57Z","timestamp":1538105097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163834314002801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S0163834314002801"],"URL":"https:\/\/doi.org\/10.1016\/j.genhosppsych.2014.10.008","relation":{},"ISSN":["0163-8343"],"issn-type":[{"value":"0163-8343","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of penicillin therapy on cognitive outcomes in neurosyphilis: a systematic review of the literature","name":"articletitle","label":"Article Title"},{"value":"General Hospital Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.genhosppsych.2014.10.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}