{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T04:42:50Z","timestamp":1792471370846,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01 MH086513"],"award-info":[{"award-number":["R01 MH086513"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["General Hospital Psychiatry"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.genhosppsych.2017.06.010","type":"journal-article","created":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T04:15:23Z","timestamp":1498191323000},"page":"51-55","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"special_numbering":"C","title":["A pilot randomized controlled trial of aerobic exercise as an adjunct to OCD treatment"],"prefix":"10.1016","volume":"49","author":[{"given":"Ana M.","family":"Abrantes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Strong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"McLaughlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah L.","family":"Garnaat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Mancebo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Riebe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Desaulniers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agustin G.","family":"Yip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin D.","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0005","article-title":"Treatment-refractory obsessive compulsive disorder","author":"Atmaca","year":"2015","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0010","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/0004867412461958","article-title":"Pharmacotherapy of obsessive-compulsive disorder: evidence-based treatment and beyond","volume":"47","author":"Fineberg","year":"2013","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0015","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jpsychires.2012.08.020","article-title":"Cognitive-behavioral therapy for obsessive-compulsive disorder: a meta-analysis of treatment outcome and moderators","volume":"47","author":"Olatunji","year":"2013","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0020","doi-asserted-by":"crossref","first-page":"233","DOI":"10.4088\/JCP.12m07657","article-title":"Five-year course of obsessive-compulsive disorder: predictors of remission and relapse","volume":"74","author":"Eisen","year":"2013","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0025","doi-asserted-by":"crossref","first-page":"685","DOI":"10.4088\/JCP.12m07789","article-title":"Treatment response, symptom remission, and wellness in obsessive-compulsive disorder","volume":"74","author":"Farris","year":"2013","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0030","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s12160-014-9685-9","article-title":"Exercise as treatment for anxiety: systematic review and analysis","volume":"49","author":"Stonerock","year":"2015","journal-title":"Ann Behav Med"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0035","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1136\/bjsports-2012-091287","article-title":"Exercise for anxiety disorders: systematic review","volume":"48","author":"Jayakody","year":"2014","journal-title":"Br J Sports Med"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0040","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1002\/da.22043","article-title":"Let's get physical: a contemporary review of the anxiolytic effects of exercise for anxiety and its disorders","volume":"30","author":"Asmundson","year":"2013","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0045","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s00702-008-0092-x","article-title":"Physical activity, exercise, depression and anxiety disorders","volume":"116","author":"Strohle","year":"2009","journal-title":"J Neural Transm"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0050","article-title":"Exercise for depression (review)","volume":"9","author":"Cooney","year":"2013","journal-title":"Cochrane Libr"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0055","first-page":"1","article-title":"Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective","author":"Bienvenu","year":"2011","journal-title":"Psychol Med"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0060","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/da.20026","article-title":"Anxiety and depressive disorders and the five-factor model of personality: a higher- and lower-order personality trait investigation in a community sample","volume":"20","author":"Bienvenu","year":"2004","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0065","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1080\/00207450590522838","article-title":"Mood in relation to subclinical obsessive-compulsive symptoms","volume":"115","author":"Spinella","year":"2005","journal-title":"Int J Neurosci"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0070","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1037\/0022-3514.67.2.319","article-title":"Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: the BIS\/BAS scales","volume":"67","author":"Carver","year":"1994","journal-title":"J Pers Soc Psychol"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0075","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.comppsych.2011.03.002","article-title":"The role of avoidance in the phenomenology of obsessive-compulsive disorder","volume":"53","author":"McGuire","year":"2012","journal-title":"Compr Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0080","first-page":"10","article-title":"Physical activity, anxiety, and stress: a review","author":"Taylor","year":"2000","journal-title":"Phys Act Psychol Well-being"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0085","first-page":"1","article-title":"Acute aerobic exercise helps overcome emotion regulation deficits","author":"Bernstein","year":"2016","journal-title":"Cognit Emot"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0090","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.psychsport.2009.05.009","article-title":"The effect of regular aerobic exercise on positive-activated affect: a meta-analysis","volume":"10","author":"Reed","year":"2009","journal-title":"Psychol Sport Exerc"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0095","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1097\/01.nmd.0000253730.31610.6c","article-title":"A pilot study of moderate-intensity aerobic exercise for obsessive compulsive disorder","volume":"195","author":"Brown R a, Abrantes AM, Strong DR, Mancebo MC, Menard J, Rasmussen S a, et al.","year":"2007","journal-title":"J Nerv Ment Dis"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0100","first-page":"53","article-title":"The effect of aerobic exercise on obsessive-compulsive disorder, anxiety, and depression: a preliminary investigation","volume":"30","author":"Lancer","year":"2007","journal-title":"Behav Ther"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0105","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1080\/16506073.2015.1016448","article-title":"A pilot test of the additive benefits of physical exercise to CBT for OCD","volume":"44","author":"Rector","year":"2015","journal-title":"Cogn Behav Ther"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0110","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.mhpa.2012.06.002","article-title":"Design and rationale for a randomized controlled trial testing the efficacy of aerobic exercise for patients with obsessive-compulsive disorder","volume":"5","author":"Abrantes","year":"2012","journal-title":"Ment Health and Phys Act"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0115","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1080\/01621459.1978.10480054","article-title":"Application of an urn model to the design of sequential controlled clinical trials","volume":"73","author":"Wei","year":"1978","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0120","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1001\/archpsyc.1989.01810110054008","article-title":"The Yale-Brown obsessive compulsive scale. II. Validity","volume":"46","author":"Goodman","year":"1989","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0125","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1001\/archpsyc.1989.01810110048007","article-title":"The Yale-Brown obsessive compulsive scale. I. Development, use, and reliability","volume":"46","author":"Goodman","year":"1989","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0130","first-page":"1","article-title":"Manual for the Beck depression inventory-II. San Antonio, TX","author":"Beck","year":"1996","journal-title":"Psychol Corp"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0135","first-page":"25","article-title":"Manual for the Beck anxiety inventory","volume":"37","author":"Beck","year":"1990","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0140","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1249\/MSS.0b013e3182630ec1","article-title":"Initial validation of an exercise \u201cvital sign\u201d in electronic medical records","volume":"44","author":"Coleman","year":"2012","journal-title":"Med Sci Sports Exerc"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0145","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1139\/h02-033","article-title":"Development and validation of a one-mile treadmill walk test to predict peak oxygen uptake in healthy adults ages 40 to 79 years","volume":"27","author":"Pober","year":"2002","journal-title":"Can J Appl Physiol"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0150","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1017\/S1461145702002900","article-title":"Treatment non-response in OCD: methodological issues and operational definitions","volume":"5","author":"Pallanti","year":"2002","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0155","series-title":"Physical activity guidelines for Americans","first-page":"1","volume":"vol. 9","author":"U.S. Department of Health and Human Services","year":"2008"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0160","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/j.2051-5545.2011.tb00014.x","article-title":"Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care","volume":"10","author":"De Hert","year":"2011","journal-title":"World Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0165","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.genhosppsych.2012.10.004","article-title":"Metabolic syndrome and obsessive-compulsive disorder: a naturalistic Italian study","volume":"35","author":"Albert","year":"2013","journal-title":"Gen Hosp Psychiatry"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0175","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/MPG.0b013e31816c749f","article-title":"Assessing the validity of clinical trials","volume":"47","author":"Akobeng","year":"2008","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.genhosppsych.2017.06.010_bb0180","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1479-5868-5-56","article-title":"A comparison of direct versus self-report measures for assessing physical activity in adults: a systematic review","volume":"5","author":"Prince","year":"2008","journal-title":"Int J Behav Nutr Phys Act"}],"container-title":["General Hospital Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163834317302074?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0163834317302074?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T01:09:35Z","timestamp":1574989775000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0163834317302074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":35,"alternative-id":["S0163834317302074"],"URL":"https:\/\/doi.org\/10.1016\/j.genhosppsych.2017.06.010","relation":{},"ISSN":["0163-8343"],"issn-type":[{"value":"0163-8343","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A pilot randomized controlled trial of aerobic exercise as an adjunct to OCD treatment","name":"articletitle","label":"Article Title"},{"value":"General Hospital Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.genhosppsych.2017.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}