{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T15:46:52Z","timestamp":1772120812087,"version":"3.50.1"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene Reports"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.genrep.2021.101236","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T02:39:20Z","timestamp":1623379160000},"page":"101236","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["SARS-CoV-2 mutations altering regulatory properties: Deciphering host's and virus's perspectives"],"prefix":"10.1016","volume":"24","author":[{"given":"Abul Bashar Mir Md. Khademul","family":"Islam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Abdullah-Al-Kamran","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.genrep.2021.101236_bb0005","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J. R. Stat. Soc. Ser. B Methodol."},{"issue":"suppl_1","key":"10.1016\/j.genrep.2021.101236_bb0010","first-page":"D149","article-title":"The microRNA.org resource: targets and expression","volume":"36","author":"Betel","year":"2008","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.genrep.2021.101236_bb0015","first-page":"661","article-title":"Mechanisms and implications of programmed translational frameshifting. Wiley interdisciplinary reviews","volume":"3","author":"Dinman","year":"2012","journal-title":"RNA"},{"issue":"7","key":"10.1016\/j.genrep.2021.101236_bb0020","doi-asserted-by":"crossref","first-page":"e22617","DOI":"10.1371\/journal.pone.0022617","article-title":"An internal ribosome entry site directs translation of the 3\u2032-gene from Pelargonium flower break virus genomic RNA: implications for infectivity","volume":"6","author":"Fern\u00e1ndez-Miragall","year":"2011","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.genrep.2021.101236_bb0025","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1586\/1744666X.2014.913482","article-title":"MicroRNAs and the immune response to respiratory virus infections","volume":"10","author":"G\u0142obi\u0144ska","year":"2014","journal-title":"Expert. Rev. Clin. Immunol."},{"issue":"Web Server issue","key":"10.1016\/j.genrep.2021.101236_bb0030","doi-asserted-by":"crossref","first-page":"W70","DOI":"10.1093\/nar\/gkn188","article-title":"The Vienna RNA websuite","volume":"36","author":"Gruber","year":"2008","journal-title":"Nucleic Acids Res."},{"issue":"D1","key":"10.1016\/j.genrep.2021.101236_bb0035","first-page":"D148","article-title":"miRTarBase 2020: updates to the experimentally validated microRNA\u2013target interaction database","volume":"48","author":"Huang","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"445","key":"10.1016\/j.genrep.2021.101236_bb0040","article-title":"The NCATS BioPlanet \u2013 an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics","volume":"10","author":"Huang","year":"2019","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.genrep.2021.101236_bb0045","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: Kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res."},{"issue":"31","key":"10.1016\/j.genrep.2021.101236_bb0050","doi-asserted-by":"crossref","first-page":"10741","DOI":"10.1074\/jbc.AC120.013449","article-title":"Structural and functional conservation of the programmed - 1 ribosomal frameshift signal of SARS coronavirus 2 (SARS-CoV-2)","volume":"295","author":"Kelly","year":"2020","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.genrep.2021.101236_bb0055","doi-asserted-by":"crossref","first-page":"37319","DOI":"10.1038\/srep37319","article-title":"Molecular analysis of the factorless internal ribosome entry site in cricket paralysis virus infection","volume":"6","author":"Kerr","year":"2016","journal-title":"Sci. Rep."},{"issue":"765","key":"10.1016\/j.genrep.2021.101236_bb0060","article-title":"Epigenetic regulator miRNA pattern differences among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 world-wide isolates delineated the mystery behind the epic pathogenicity and distinct clinical characteristics of pandemic COVID-19","volume":"11","author":"Khan","year":"2020","journal-title":"Front. Genet."},{"issue":"suppl_2","key":"10.1016\/j.genrep.2021.101236_bb0065","doi-asserted-by":"crossref","first-page":"W451","DOI":"10.1093\/nar\/gkl243","article-title":"RNAhybrid: microRNA target prediction easy, fast and flexible","volume":"34","author":"Kr\u00fcger","year":"2006","journal-title":"Nucleic Acids Res."},{"issue":"W1","key":"10.1016\/j.genrep.2021.101236_bb0070","doi-asserted-by":"crossref","first-page":"W435","DOI":"10.1093\/nar\/gkx279","article-title":"IntaRNA 2.0: enhanced and customizable prediction of RNA-RNA interactions","volume":"45","author":"Mann","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.genrep.2021.101236_bb0075","first-page":"6(5)","article-title":"Gitools: analysis and visualisation of genomic data using interactive heat-maps","author":"Perez-Llamas","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.genrep.2021.101236_bb0080","doi-asserted-by":"crossref","first-page":"279","DOI":"10.3390\/v5010279","article-title":"Altering SARS coronavirus frameshift efficiency affects genomic and subgenomic RNA production","volume":"5","author":"Plant","year":"2013","journal-title":"Viruses"},{"issue":"2","key":"10.1016\/j.genrep.2021.101236_bb0085","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.virol.2005.10.013","article-title":"Down-regulation of the internal ribosome entry site (IRES)-mediated translation of the hepatitis C virus: critical role of binding of the stem-loop IIId domain of IRES and the viral core protein","volume":"345","author":"Shimoike","year":"2006","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.genrep.2021.101236_bb0090","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.molmed.2016.11.003","article-title":"MicroRNA regulation of RNA virus replication and pathogenesis","volume":"23","author":"Trobaugh","year":"2017","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.genrep.2021.101236_bb0095","series-title":"Coronavirus Cases","first-page":"1","author":"Worldometer","year":"2020"},{"issue":"2","key":"10.1016\/j.genrep.2021.101236_bb0100","first-page":"212","article-title":"The 2019 novel coronavirus resource","volume":"42","author":"Zhao","year":"2020","journal-title":"Yi Chuan"}],"container-title":["Gene Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452014421002211?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452014421002211?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:16:48Z","timestamp":1762528608000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452014421002211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":20,"alternative-id":["S2452014421002211"],"URL":"https:\/\/doi.org\/10.1016\/j.genrep.2021.101236","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.06.15.150482","asserted-by":"object"}]},"ISSN":["2452-0144"],"issn-type":[{"value":"2452-0144","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SARS-CoV-2 mutations altering regulatory properties: Deciphering host's and virus's perspectives","name":"articletitle","label":"Article Title"},{"value":"Gene Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.genrep.2021.101236","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101236"}}