{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T23:28:25Z","timestamp":1778282905566,"version":"3.51.4"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene Reports"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.genrep.2022.101495","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T02:35:29Z","timestamp":1642127729000},"page":"101495","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Enhanced endocytosis elevated virulence and severity of SARS-CoV-2 due to hyperglycemia in type 2 diabetic patients"],"prefix":"10.1016","volume":"26","author":[{"given":"Kannan","family":"Subbaram","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Shaik Syed","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheeza","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.genrep.2022.101495_bb0005","doi-asserted-by":"crossref","first-page":"576818","DOI":"10.3389\/fimmu.2020.576818","article-title":"Impact of diabetes in patients diagnosed with COVID-19","volume":"11","author":"Abu-Farha","year":"2020","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.genrep.2022.101495_bb0010","doi-asserted-by":"crossref","first-page":"e48","DOI":"10.1016\/S2213-2600(20)30237-X","article-title":"High prevalence of putative invasive pulmonary aspergillosis in critically ill COVID-19 patients","volume":"8","author":"Alanio","year":"2020","journal-title":"Lancet Respir. Med."},{"issue":"Suppl1","key":"10.1016\/j.genrep.2022.101495_bb0015","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.4103\/2230-8210.94253","article-title":"Infections in patients with diabetes mellitus: a review of pathogenesis","volume":"Suppl 1","author":"Alves","year":"2012","journal-title":"Indian J Endocrinol Metab."},{"issue":"3","key":"10.1016\/j.genrep.2022.101495_bb0020","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.dsx.2020.03.013","article-title":"Cardiovascular disease and covid-19","volume":"14","author":"Bansal","year":"2020","journal-title":"Diabetes Metab Syndr."},{"key":"10.1016\/j.genrep.2022.101495_bb0025","doi-asserted-by":"crossref","first-page":"e3331","DOI":"10.1002\/dmrr.3331","article-title":"In response: diabetes is a risk factor for the progression and prognosis of COVID-19","author":"Blanke","year":"2020","journal-title":"Diabetes Metab. Res. Rev."},{"issue":"6","key":"10.1016\/j.genrep.2022.101495_bb0030","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/S2213-8587(20)30152-2","article-title":"Practical recommendations for the management of diabetes in patients with COVID-19","volume":"8","author":"Bornstein","year":"2020","journal-title":"Lancet Diabetes Endocrinol."},{"issue":"7","key":"10.1016\/j.genrep.2022.101495_bb0035","doi-asserted-by":"crossref","first-page":"ofab016","DOI":"10.1093\/ofid\/ofab016","article-title":"Opportunistic Fungal Infection Associated with COVID-19","volume":"8","author":"Cafardi","year":"2021","journal-title":"Open Forum Infect. Dis."},{"issue":"6518","key":"10.1016\/j.genrep.2022.101495_bb0040","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1126\/science.abd2985","article-title":"Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity","volume":"370","author":"Cantuti-Castelvetri","year":"2020","journal-title":"Science."},{"key":"10.1016\/j.genrep.2022.101495_bb0045","doi-asserted-by":"crossref","first-page":"108186","DOI":"10.1016\/j.diabres.2020.108186","article-title":"Hyperglycemia and the worse prognosis of covid-19. Why a fast blood glucose control should be mandatory","volume":"163","author":"Ceriello","year":"2020","journal-title":"Diabetes Res. Clin. Pract."},{"issue":"10085","key":"10.1016\/j.genrep.2022.101495_bb0050","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1016\/S0140-6736(17)30058-2","article-title":"Type 2 diabetes","volume":"389","author":"Chatterjee","year":"2017","journal-title":"Lancet."},{"issue":"7","key":"10.1016\/j.genrep.2022.101495_bb0055","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.2337\/dc20-0660","article-title":"Clinical characteristics and outcomes of patients with diabetes and COVID-19 in association with glucose-lowering medication","volume":"43","author":"Chen","year":"2020","journal-title":"Diabetes Care"},{"issue":"7","key":"10.1016\/j.genrep.2022.101495_bb0060","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/crj.13369","article-title":"Clinical and etiological analysis of co-infections and secondary infections in Covid-19 patients: an observational study","volume":"15","author":"Chen","year":"2021","journal-title":"Clin. Respir. J."},{"issue":"1","key":"10.1016\/j.genrep.2022.101495_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/S2666-5247(20)30009-4","article-title":"Co-infections: potentially lethal and unexplored in Covid-19","volume":"1","author":"Cox","year":"2020","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.genrep.2022.101495_bb0070","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3389\/fmed.2020.00199","article-title":"Diabetic kidney disease and covid-19: the crash of two pandemics","volume":"7","author":"D\u2019Marco","year":"2020","journal-title":"Front Med (Lausanne)"},{"issue":"1","key":"10.1016\/j.genrep.2022.101495_bb0075","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12933-021-01286-7","article-title":"Glycated ACE2 receptor in diabetes: open door for SARS-COV-2 entry in cardiomyocyte","volume":"20","author":"D\u2019Onofrio","year":"2021","journal-title":"Cardiovasc. Diabetol."},{"key":"10.1016\/j.genrep.2022.101495_bb0080","doi-asserted-by":"crossref","first-page":"678771","DOI":"10.3389\/fimmu.2021.678771","article-title":"A bittersweet response to infection in diabetes; targeting neutrophils to modify inflammation and improve host immunity","volume":"12","author":"Dowey","year":"2021","journal-title":"Front Immunol."},{"key":"10.1016\/j.genrep.2022.101495_bb0085","doi-asserted-by":"crossref","first-page":"101044","DOI":"10.1016\/j.molmet.2020.101044","article-title":"Diabetes, infection risk and covid-19","volume":"39","author":"Erener","year":"2020","journal-title":"Mol Metab."},{"issue":"11","key":"10.1016\/j.genrep.2022.101495_bb0090","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.7196\/SAMJ.2020.v110i11.15248","article-title":"Opportunistic pathogenic fungal co-infections are prevalent in critically ill COVID-19 patients: are they risk factors for disease severity?","volume":"110","author":"Ezeokoli","year":"2020","journal-title":"S. Afr. Med. J."},{"issue":"9","key":"10.1016\/j.genrep.2022.101495_bb0095","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1002\/cbin.11403","article-title":"Lymphopenia in covid-19: therapeutic opportunities","volume":"44","author":"Fathi","year":"2020","journal-title":"Cell Biol. Int."},{"issue":"3\u20134","key":"10.1016\/j.genrep.2022.101495_bb0100","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1900\/RDS.2014.11.202","article-title":"Adverse effects of GLP-1 receptor agonists","volume":"11","author":"Filippatos","year":"2014","journal-title":"Rev. Diabet. Stud."},{"issue":"12","key":"10.1016\/j.genrep.2022.101495_bb0105","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003794","article-title":"Host susceptibility factors to bacterial infections in type 2 diabetes","volume":"9","author":"Gan","year":"2013","journal-title":"PLoS Pathog."},{"issue":"2","key":"10.1016\/j.genrep.2022.101495_bb0110","doi-asserted-by":"crossref","first-page":"100971","DOI":"10.1016\/j.mycmed.2020.100971","article-title":"Invasive fungal diseases during COVID-19: we should be prepared","volume":"30","author":"Gangneux","year":"2020","journal-title":"J. Mycol. Med."},{"issue":"1","key":"10.1016\/j.genrep.2022.101495_bb0115","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.cmi.2020.07.041","article-title":"Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study","volume":"27","author":"Garcia-Vidal","year":"2021","journal-title":"Clin. Microbiol. Infect."},{"issue":"9733","key":"10.1016\/j.genrep.2022.101495_bb0120","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1016\/S0140-6736(10)60973-7","article-title":"More insights on the dysglycaemia-cardiovascular connection","volume":"375","author":"Gerstein","year":"2010","journal-title":"Lancet."},{"issue":"10","key":"10.1016\/j.genrep.2022.101495_bb0125","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1161\/CIRCRESAHA.120.317015","article-title":"Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system","volume":"126","author":"Gheblawi","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.genrep.2022.101495_bb0130","doi-asserted-by":"crossref","first-page":"e3319","DOI":"10.1002\/dmrr.3319","article-title":"Diabetes is a risk factor for the progression and prognosis of COVID-19","author":"Guo","year":"2020","journal-title":"Diabetes Metab. Res. Rev."},{"issue":"1","key":"10.1016\/j.genrep.2022.101495_bb0135","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1038\/s41467-019-10189-x","article-title":"Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic \u03b2-cells","volume":"10","author":"Haythorne","year":"2019","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.genrep.2022.101495_bb0140","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0249668","article-title":"Clinical characteristics of Covid-19 patients with clinically diagnosed bacterial co-infection: a multi-center study","volume":"16","author":"He","year":"2021","journal-title":"PLoS One"},{"issue":"5930","key":"10.1016\/j.genrep.2022.101495_bb0145","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1126\/science.1160809","article-title":"Understanding the warburg effect: the metabolic requirements of cell proliferation","volume":"324","author":"Heiden","year":"2009","journal-title":"Science."},{"issue":"1","key":"10.1016\/j.genrep.2022.101495_bb0150","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/MED.0000000000000311","article-title":"An update on sodium-glucose co-transporter-2 inhibitors for the treatment of diabetes mellitus","volume":"24","author":"Hsia","year":"2017","journal-title":"Curr. Opin. Endocrinol. Diabetes Obes."},{"key":"10.1016\/j.genrep.2022.101495_bb0155","doi-asserted-by":"crossref","first-page":"108142","DOI":"10.1016\/j.diabres.2020.108142","article-title":"Covid-19 and diabetes: knowledge in progress","volume":"162","author":"Hussain","year":"2020","journal-title":"Diabetes Res. Clin. Pract."},{"key":"10.1016\/j.genrep.2022.101495_bb0160","doi-asserted-by":"crossref","first-page":"602735","DOI":"10.3389\/fendo.2021.602735","article-title":"Severity of covid-19 and Treatment strategy for patient with diabetes","volume":"12","author":"Jin","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"10.1016\/j.genrep.2022.101495_bb0165","first-page":"2006","article-title":"COVID-19 (Novel coronavirus 2019) - recent trends","volume":"24","author":"Kannan","year":"2020","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"12","key":"10.1016\/j.genrep.2022.101495_bb0170","first-page":"4405","article-title":"Evolving biothreat of variant SARS-CoV-2 - molecular properties, virulence and epidemiology","volume":"25","author":"Kannan","year":"2021","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"6","key":"10.1016\/j.genrep.2022.101495_bb0175","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1016\/j.dsx.2020.10.001","article-title":"Pattern of liver function and clinical profile in covid-19: a cross-sectional study of 91 patients","volume":"14","author":"Kumar","year":"2020","journal-title":"Diabetes Metab Syndr."},{"issue":"4","key":"10.1016\/j.genrep.2022.101495_bb0180","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/jmv.25685","article-title":"Coronavirus infections and immune responses","volume":"92","author":"Li","year":"2020","journal-title":"J. Med. Virol."},{"issue":"4","key":"10.1016\/j.genrep.2022.101495_bb0185","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s15010-017-0991-6","article-title":"Pulmonary mucormycosis: clinical features and outcomes","volume":"45","author":"Lin","year":"2017","journal-title":"Infection."},{"issue":"1","key":"10.1016\/j.genrep.2022.101495_bb0190","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1080\/22221751.2020.1746199","article-title":"Hypothesis for potential pathogenesis of SARS-CoV-2 infection\u2013a review of immune changes in patients with viral pneumonia","volume":"9","author":"Lin","year":"2020","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.genrep.2022.101495_bb0195","doi-asserted-by":"crossref","first-page":"102763","DOI":"10.1016\/j.ebiom.2020.102763","article-title":"Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients","volume":"55","author":"Liu","year":"2020","journal-title":"EBioMedicine."},{"key":"10.1016\/j.genrep.2022.101495_bb0200","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12979-020-00192-y","article-title":"SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done?","volume":"17","author":"Mazucanti","year":"2020","journal-title":"Immun. Ageing"},{"issue":"15","key":"10.1016\/j.genrep.2022.101495_bb0205","doi-asserted-by":"crossref","first-page":"7762","DOI":"10.3390\/ijms22157762","article-title":"Diabetic nephropathy and covid-19: the potential role of immune actors","volume":"22","author":"Mourad","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"9","key":"10.1016\/j.genrep.2022.101495_bb0210","doi-asserted-by":"crossref","first-page":"999","DOI":"10.3390\/cells8090999","article-title":"Hyperglycemia-induced aberrant cell proliferation; a metabolic challenge mediated by protein O-GlcNAc modification","volume":"8","author":"Nagy","year":"2019","journal-title":"Cells."},{"key":"10.1016\/j.genrep.2022.101495_bb0215","article-title":"COVID-19-associated mucormycosis: an updated systematic review of literature","volume":"16","author":"Pal","year":"2021","journal-title":"Mycoses"},{"issue":"5","key":"10.1016\/j.genrep.2022.101495_bb0220","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s11739-020-02389-x","article-title":"Potential role of incretins in diabetes and COVID-19 infection: a hypothesis worth exploring","volume":"15","author":"Pantanetti","year":"2020","journal-title":"Intern. Emerg. Med."},{"issue":"12","key":"10.1016\/j.genrep.2022.101495_bb0225","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.21037\/jtd.2019.12.53","article-title":"Clinical features of pulmonary mucormycosis in patients with different immune status","volume":"11","author":"Peng","year":"2019","journal-title":"J. Thorac. Dis."},{"issue":"20","key":"10.1016\/j.genrep.2022.101495_bb0230","doi-asserted-by":"crossref","first-page":"5416","DOI":"10.1182\/blood-2011-07-366526","article-title":"Mucorales-specific T cells emerge in the course of invasive mucormycosis and may be used as a surrogate diagnostic marker in high-risk patients","volume":"118","author":"Potenza","year":"2011","journal-title":"Blood."},{"issue":"12","key":"10.1016\/j.genrep.2022.101495_bb0235","doi-asserted-by":"crossref","first-page":"6732","DOI":"10.1002\/jmv.27256","article-title":"Therapeutic interventions of remdesivir in diabetic and nondiabetic COVID-19 patients: a prospective observational study conducted on Pakistani population","volume":"93","author":"Qureshi","year":"2021","journal-title":"J. Med. Virol."},{"issue":"12","key":"10.1016\/j.genrep.2022.101495_bb0240","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/1753-0407.13085","article-title":"Factors leading to high morbidity and mortality of covid-19 in patients with type 2 diabetes","volume":"12","author":"Rajpal","year":"2020","journal-title":"J. Diabetes"},{"key":"10.1016\/j.genrep.2022.101495_bb0245","doi-asserted-by":"crossref","first-page":"108286","DOI":"10.1016\/j.diabres.2020.108286","article-title":"Well-controlled vs poorly-controlled diabetes in patients with COVID-19: are there any differences in outcomes and imaging findings?","volume":"166","author":"Raoufi","year":"2020","journal-title":"Diabetes Res. Clin. Pract."},{"key":"10.1016\/j.genrep.2022.101495_bb0250","doi-asserted-by":"crossref","first-page":"629933","DOI":"10.3389\/fcvm.2020.629933","article-title":"Why is covid-19 more severe in patients with diabetes? The role of angiotensin-converting enzyme 2, endothelial dysfunction and the immunoinflammatory system","volume":"7","author":"Roberts","year":"2021","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.genrep.2022.101495_bb0255","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.2147\/IDR.S314029","article-title":"Coinfections in patients hospitalized with covid-19: a descriptive study from the United Arab Emirates","volume":"14","author":"Senok","year":"2021","journal-title":"Infect Drug Resist."},{"key":"10.1016\/j.genrep.2022.101495_bb0260","doi-asserted-by":"crossref","first-page":"107503","DOI":"10.1016\/j.pharmthera.2020.107503","article-title":"Dipeptidyl peptidase 4 inhibitors and their potential immune modulatory functions","volume":"209","author":"Shao","year":"2020","journal-title":"Pharmacol. Ther."},{"issue":"5","key":"10.1016\/j.genrep.2022.101495_bb0265","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1038\/s41418-020-0530-3","article-title":"Covid-19 infection: the perspectives on immune responses","volume":"27","author":"Shi","year":"2020","journal-title":"Cell Death Differ."},{"issue":"4","key":"10.1016\/j.genrep.2022.101495_bb0270","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.dsx.2020.04.004","article-title":"Diabetes in covid-19: prevalence, pathophysiology, prognosis and practical considerations","volume":"14","author":"Singh","year":"2020","journal-title":"Diabetol. Metab. Syndr."},{"issue":"4","key":"10.1016\/j.genrep.2022.101495_bb0275","doi-asserted-by":"crossref","first-page":"102146","DOI":"10.1016\/j.dsx.2021.05.019","article-title":"Mucormycosis in COVID-19: a systematic review of cases reported worldwide and in India","volume":"15","author":"Singh","year":"2021","journal-title":"Diabetes Metab. Syndr."},{"issue":"4","key":"10.1016\/j.genrep.2022.101495_bb0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2014.03.009","article-title":"Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication","volume":"19","author":"Thai","year":"2014","journal-title":"Cell Metab."},{"issue":"1","key":"10.1016\/j.genrep.2022.101495_bb0285","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12915-019-0678-9","article-title":"Viral hijacking of cellular metabolism","volume":"17","author":"Thaker","year":"2019","journal-title":"BMC Biol."},{"issue":"6","key":"10.1016\/j.genrep.2022.101495_bb0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1009634","article-title":"Diabetes and coronavirus (SARS-CoV-2): molecular mechanism of metformin intervention and the scientific basis of drug repurposing","volume":"17","author":"Varghese","year":"2021","journal-title":"PLoS Pathog."},{"issue":"2","key":"10.1016\/j.genrep.2022.101495_bb0295","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/cid\/ciz391","article-title":"Influenza coinfection: be(a)ware of invasive aspergillosis","volume":"70","author":"Verweij","year":"2020","journal-title":"Clin. Infect. Dis."},{"issue":"2","key":"10.1016\/j.genrep.2022.101495_bb0300","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1016\/S2666-5247(20)30027-6","article-title":"Diagnosing COVID-19-associated pulmonary aspergillosis","volume":"1","author":"Verweij","year":"2020","journal-title":"Lancet Microbe"},{"issue":"11","key":"10.1016\/j.genrep.2022.101495_bb0305","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/jama.2020.1585","article-title":"Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China","volume":"323","author":"Wang","year":"2020","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.genrep.2022.101495_bb0310","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1001\/jamainternmed.2020.0994","article-title":"Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China","volume":"180","author":"Wu","year":"2020","journal-title":"JAMA Intern. Med."},{"issue":"5","key":"10.1016\/j.genrep.2022.101495_bb0315","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0251916","article-title":"DPP-4 inhibitors may improve the mortality of coronavirus disease 2019: a meta-analysis","volume":"16","author":"Yang","year":"2021","journal-title":"PLoS One"},{"issue":"10229","key":"10.1016\/j.genrep.2022.101495_bb0320","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","article-title":"Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study","volume":"395","author":"Zhou","year":"2020","journal-title":"Lancet."},{"issue":"8","key":"10.1016\/j.genrep.2022.101495_bb0325","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A novel coronavirus from patients with pneumonia in China, 2019","volume":"382","author":"Zhu","year":"2020","journal-title":"N. Engl. J. Med."}],"container-title":["Gene Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452014422000036?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2452014422000036?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T15:16:51Z","timestamp":1762528611000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2452014422000036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":65,"alternative-id":["S2452014422000036"],"URL":"https:\/\/doi.org\/10.1016\/j.genrep.2022.101495","relation":{},"ISSN":["2452-0144"],"issn-type":[{"value":"2452-0144","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhanced endocytosis elevated virulence and severity of SARS-CoV-2 due to hyperglycemia in type 2 diabetic patients","name":"articletitle","label":"Article Title"},{"value":"Gene Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.genrep.2022.101495","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101495"}}