{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:08:29Z","timestamp":1776038909400,"version":"3.50.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gene Expression Patterns"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.gep.2008.01.001","type":"journal-article","created":{"date-parts":[[2008,1,21]],"date-time":"2008-01-21T12:19:07Z","timestamp":1200917947000},"page":"217-226","source":"Crossref","is-referenced-by-count":15,"title":["Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues"],"prefix":"10.1016","volume":"8","author":[{"given":"Jorge B.","family":"Aquino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Marmig\u00e8re","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Lallemend","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. Kalle","family":"Lundgren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo J.","family":"Villar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Wegner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrik","family":"Ernfors","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"37","key":"10.1016\/j.gep.2008.01.001_bib1","doi-asserted-by":"crossref","first-page":"29153","DOI":"10.1074\/jbc.M003926200","article-title":"GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase","volume":"275","author":"Anneren","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.gep.2008.01.001_bib2","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.expneurol.2005.12.015","article-title":"In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells","volume":"198","author":"Aquino","year":"2006","journal-title":"Exp. Neurol."},{"issue":"44","key":"10.1016\/j.gep.2008.01.001_bib4","doi-asserted-by":"crossref","first-page":"6448","DOI":"10.1038\/sj.onc.1204785","article-title":"Functions of the adapter protein Cas: signal convergence and the determination of cellular responses","volume":"20","author":"Bouton","year":"2001","journal-title":"Oncogene"},{"issue":"4","key":"10.1016\/j.gep.2008.01.001_bib5","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0092-8674(00)80853-3","article-title":"A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube","volume":"101","author":"Briscoe","year":"2000","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.gep.2008.01.001_bib6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1006\/dbio.2002.0828","article-title":"Properties of a fetal multipotent neural stem cell (NEP cell)","volume":"251","author":"Cai","year":"2002","journal-title":"Dev. Biol."},{"issue":"1","key":"10.1016\/j.gep.2008.01.001_bib7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0165-3806(94)00162-S","article-title":"Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system","volume":"84","author":"Dahlstrand","year":"1995","journal-title":"Brain Res. Dev. Brain Res."},{"issue":"16","key":"10.1016\/j.gep.2008.01.001_bib8","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.1242\/dev.124.16.3111","article-title":"Temporally-regulated retinoic acid depletion produces specific neural crest, ocular and nervous system defects","volume":"124","author":"Dickman","year":"1997","journal-title":"Development"},{"issue":"5063","key":"10.1016\/j.gep.2008.01.001_bib9","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1126\/science.1350865","article-title":"Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1","volume":"256","author":"Ericson","year":"1992","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.gep.2008.01.001_bib10","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1074\/jbc.273.4.2336","article-title":"Protein kinase C-dependent tyrosine phosphorylation of p130cas in differentiating neuroblastoma cells","volume":"273","author":"Fagerstrom","year":"1998","journal-title":"J. Biol. Chem."},{"issue":"Pt 1","key":"10.1016\/j.gep.2008.01.001_bib11","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1242\/jcs.115.1.99","article-title":"Dissection of HEF1-dependent functions in motility and transcriptional regulation","volume":"115","author":"Fashena","year":"2002","journal-title":"J. Cell Sci."},{"issue":"1","key":"10.1016\/j.gep.2008.01.001_bib12","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1242\/dev.02702","article-title":"The TGFbeta intracellular effector Smad3 regulates neuronal differentiation and cell fate specification in the developing spinal cord","volume":"134","author":"Garcia-Campmany","year":"2007","journal-title":"Development"},{"issue":"5","key":"10.1016\/j.gep.2008.01.001_bib13","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0896-6273(03)00497-5","article-title":"SOX2 functions to maintain neural progenitor identity","volume":"39","author":"Graham","year":"2003","journal-title":"Neuron"},{"issue":"23","key":"10.1016\/j.gep.2008.01.001_bib14","doi-asserted-by":"crossref","first-page":"13649","DOI":"10.1074\/jbc.271.23.13649","article-title":"p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase","volume":"271","author":"Harte","year":"1996","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.gep.2008.01.001_bib15","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/(SICI)1520-6408(1999)25:4<353::AID-DVG9>3.0.CO;2-G","article-title":"Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways","volume":"25","author":"Haselbeck","year":"1999","journal-title":"Dev. Genet."},{"issue":"1","key":"10.1016\/j.gep.2008.01.001_bib16","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0959-4388(03)00010-2","article-title":"Specification of dorsal spinal cord interneurons","volume":"13","author":"Helms","year":"2003","journal-title":"Curr. Opin. Neurobiol."},{"issue":"11","key":"10.1016\/j.gep.2008.01.001_bib17","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1242\/dev.01852","article-title":"The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes","volume":"132","author":"Hjerling-Leffler","year":"2005","journal-title":"Development"},{"issue":"4","key":"10.1016\/j.gep.2008.01.001_bib18","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/1246","article-title":"Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas","author":"Honda","year":"1998","journal-title":"Nat. Genet."},{"issue":"11","key":"10.1016\/j.gep.2008.01.001_bib19","first-page":"2331","article-title":"Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn","volume":"11","author":"Ishino","year":"1995","journal-title":"Oncogene"},{"issue":"2","key":"10.1016\/j.gep.2008.01.001_bib20","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1242\/dev.124.2.313","article-title":"Genetic evidence that the retinoid signal is transduced by heterodimeric RXR\/RAR functional units during mouse development","volume":"124","author":"Kastner","year":"1997","journal-title":"Development"},{"issue":"7","key":"10.1016\/j.gep.2008.01.001_bib21","doi-asserted-by":"crossref","first-page":"3327","DOI":"10.1128\/MCB.16.7.3327","article-title":"Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae","volume":"16","author":"Law","year":"1996","journal-title":"Mol. Cell. Biol."},{"issue":"6","key":"10.1016\/j.gep.2008.01.001_bib22","doi-asserted-by":"crossref","first-page":"3540","DOI":"10.1128\/MCB.18.6.3540","article-title":"Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments","volume":"18","author":"Law","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.gep.2008.01.001_bib23","doi-asserted-by":"crossref","first-page":"6759","DOI":"10.1093\/emboj\/19.24.6759","article-title":"A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member, HEF1\/NEDD9\/CAS-L","volume":"19","author":"Liu","year":"2000","journal-title":"EMBO J."},{"issue":"1\u20136","key":"10.1016\/j.gep.2008.01.001_bib24","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/0960-0760(95)00094-G","article-title":"Developmental roles of the retinoic acid receptors","volume":"53","author":"Lohnes","year":"1995","journal-title":"J. Steroid Biochem. Mol. Biol."},{"issue":"1","key":"10.1016\/j.gep.2008.01.001_bib25","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0092-8674(00)81321-5","article-title":"Identification of neurogenin, a vertebrate neuronal determination gene","volume":"87","author":"Ma","year":"1996","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.gep.2008.01.001_bib26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ydbio.2004.09.014","article-title":"Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect","volume":"277","author":"Maka","year":"2005","journal-title":"Dev. Biol."},{"issue":"2","key":"10.1016\/j.gep.2008.01.001_bib27","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1038\/nn1631","article-title":"The Runx1\/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons","author":"Marmig\u00e8re","year":"2006","journal-title":"Nat. Neurosci."},{"issue":"3","key":"10.1016\/j.gep.2008.01.001_bib28","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/dvdy.20159","article-title":"Crk-associated substrate (Cas) family member, NEDD9, is regulated in human neuroblastoma cells and in the embryonic hindbrain by all-trans retinoic acid","volume":"231","author":"Merrill","year":"2004","journal-title":"Dev. Dyn."},{"issue":"9","key":"10.1016\/j.gep.2008.01.001_bib29","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1242\/dev.129.9.2271","article-title":"Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice","volume":"129","author":"Mic","year":"2002","journal-title":"Development"},{"issue":"4","key":"10.1016\/j.gep.2008.01.001_bib30","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1084\/jem.184.4.1365","article-title":"Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes","volume":"184","author":"Minegishi","year":"1996","journal-title":"J. Exp. Med."},{"issue":"12","key":"10.1016\/j.gep.2008.01.001_bib31","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1038\/sj.onc.1209199","article-title":"HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells","volume":"25","author":"Natarajan","year":"2006","journal-title":"Oncogene"},{"issue":"2","key":"10.1016\/j.gep.2008.01.001_bib32","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0896-6273(01)00214-8","article-title":"Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors","volume":"29","author":"Nieto","year":"2001","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.gep.2008.01.001_bib33","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0962-8924(99)01714-6","article-title":"Integrin signalling: a new Cas(t) of characters enters the stage","volume":"10","author":"O\u2019Neill","year":"2000","journal-title":"Trends Cell Biol."},{"issue":"1","key":"10.1016\/j.gep.2008.01.001_bib34","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1172\/JCI24497","article-title":"Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice","volume":"116","author":"Peng","year":"2006","journal-title":"J. Clin. Invest."},{"issue":"7","key":"10.1016\/j.gep.2008.01.001_bib35","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1101\/gad.9.7.769","article-title":"A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1","volume":"9","author":"Perlmann","year":"1995","journal-title":"Genes Dev."},{"issue":"17","key":"10.1016\/j.gep.2008.01.001_bib36","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1242\/dev.124.17.3263","article-title":"NeuroM, a neural helix\u2013loop\u2013helix transcription factor, defines a new transition stage in neurogenesis","volume":"124","author":"Roztocil","year":"1997","journal-title":"Development"},{"issue":"16","key":"10.1016\/j.gep.2008.01.001_bib37","doi-asserted-by":"crossref","first-page":"3748","DOI":"10.1002\/j.1460-2075.1994.tb06684.x","article-title":"A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner","volume":"13","author":"Sakai","year":"1994","journal-title":"EMBO J."},{"issue":"3","key":"10.1016\/j.gep.2008.01.001_bib38","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0092-8674(01)00224-0","article-title":"Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms","volume":"104","author":"Sun","year":"2001","journal-title":"Cell"},{"issue":"7","key":"10.1016\/j.gep.2008.01.001_bib39","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/10862","article-title":"Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes","volume":"17","author":"Wagner","year":"1999","journal-title":"Nat. Biotechnol."},{"issue":"6","key":"10.1016\/j.gep.2008.01.001_bib40","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1006\/mcne.2001.1057","article-title":"Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem","volume":"18","author":"Wallen","year":"2001","journal-title":"Mol. Cell. Neurosci."},{"issue":"20","key":"10.1016\/j.gep.2008.01.001_bib41","doi-asserted-by":"crossref","first-page":"17406","DOI":"10.1074\/jbc.M111902200","article-title":"c-SRC mediates neurite outgrowth through recruitment of Crk to the scaffolding protein Sin\/Efs without altering the kinetics of ERK activation","volume":"277","author":"Yang","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"5310","key":"10.1016\/j.gep.2008.01.001_bib42","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1126\/science.276.5310.248","article-title":"Dopamine neuron agenesis in Nurr1-deficient mice","volume":"276","author":"Zetterstrom","year":"1997","journal-title":"Science"},{"issue":"20","key":"10.1016\/j.gep.2008.01.001_bib43","doi-asserted-by":"crossref","first-page":"7610","DOI":"10.1523\/JNEUROSCI.23-20-07610.2003","article-title":"The meninges is a source of retinoic acid for the late-developing hindbrain","volume":"23","author":"Zhang","year":"2003","journal-title":"J. Neurosci."},{"issue":"Pt 1","key":"10.1016\/j.gep.2008.01.001_bib44","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1242\/jcs.02712","article-title":"Cell adhesion regulates Ser\/Thr phosphorylation and proteasomal degradation of HEF1","volume":"119","author":"Zheng","year":"2006","journal-title":"J. Cell Sci."}],"container-title":["Gene Expression Patterns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567133X08000197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567133X08000197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T03:45:23Z","timestamp":1630554323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567133X08000197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S1567133X08000197"],"URL":"https:\/\/doi.org\/10.1016\/j.gep.2008.01.001","relation":{},"ISSN":["1567-133X"],"issn-type":[{"value":"1567-133X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}