{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T16:16:40Z","timestamp":1773418600732,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"3-4","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gene Expression Patterns"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1016\/j.gep.2010.12.003","type":"journal-article","created":{"date-parts":[[2010,12,17]],"date-time":"2010-12-17T09:29:29Z","timestamp":1292578169000},"page":"221-232","source":"Crossref","is-referenced-by-count":16,"title":["Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis"],"prefix":"10.1016","volume":"11","author":[{"given":"Nils O.","family":"Lindstr\u00f6m","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Neves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"McIntosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zosia","family":"Miedzybrodzka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil","family":"Vargesson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Martin Collinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gep.2010.12.003_b0005","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1369\/jhc.5C6813.2006","article-title":"LIM kinase 2 is widely expressed in all tissues","volume":"54","author":"Acevedo","year":"2006","journal-title":"Journal of Histochemistry and Cytochemistry"},{"key":"10.1016\/j.gep.2010.12.003_b0010","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/31729","article-title":"Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase","volume":"393","author":"Arber","year":"1998","journal-title":"Nature"},{"issue":"1993","key":"10.1016\/j.gep.2010.12.003_b0015","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0925-4773(93)90090-K","article-title":"The expression of the Wilms-tumor gene, Wt1, in the developing mammalian embryo","volume":"40","author":"Armstrong","year":"1993","journal-title":"Mechanisms of Development"},{"key":"10.1016\/j.gep.2010.12.003_b0020","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.biocel.2006.11.011","article-title":"Lim kinases, regulators of actin dynamics","volume":"39","author":"Bernard","year":"2007","journal-title":"International Journal of Biochemistry and Cell Biology"},{"key":"10.1016\/j.gep.2010.12.003_b0025","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.tcb.2010.01.001","article-title":"ADF\/cofilin: a functional node in cell biology","volume":"20","author":"Bernstein","year":"2010","journal-title":"Trends in Cell Biology"},{"key":"10.1016\/j.gep.2010.12.003_b0030","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1002\/dvdy.10124","article-title":"Clonal analysis of patterns of growth, stem cell activity, and cell movement during the development and maintenance of the murine corneal epithelium","volume":"224","author":"Collinson","year":"2002","journal-title":"Developmental Dynamics"},{"key":"10.1016\/j.gep.2010.12.003_b0035","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1002\/bies.950190810","article-title":"Molecular aspects of the epithelial phenotype","volume":"19","author":"Davies","year":"1997","journal-title":"BioEssays"},{"key":"10.1016\/j.gep.2010.12.003_b0040","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/hmg\/ddh015","article-title":"Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation","volume":"13","author":"Davies","year":"2004","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/j.gep.2010.12.003_b0045","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1476-4598-6-40","article-title":"Expression of LIM kinase 1 is associated with reversible G1\/S phase arrest, chromosomal instability and prostate cancer","volume":"6","author":"Davila","year":"2007","journal-title":"Molecular Cancer"},{"key":"10.1016\/j.gep.2010.12.003_b0050","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.neuron.2005.08.010","article-title":"LIM kinase1 controls synaptic stability downstream of the type II BMP receptor","volume":"47","author":"Eaton","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.gep.2010.12.003_b0055","doi-asserted-by":"crossref","first-page":"4637","DOI":"10.1128\/MCB.23.13.4637-4648.2003","article-title":"Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina","volume":"23","author":"Fan","year":"2003","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.gep.2010.12.003_b0060","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.yexcr.2003.11.024","article-title":"LIM kinase 1, a key regulator of actin dynamics, is widely expressed in embryonic and adult tissues","volume":"294","author":"Foletta","year":"2004","journal-title":"Experimental Cell Research"},{"key":"10.1016\/j.gep.2010.12.003_b0065","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ydbio.2009.05.578","article-title":"Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment","volume":"332","author":"Georgas","year":"2009","journal-title":"Developmental Biology"},{"key":"10.1016\/j.gep.2010.12.003_b0070","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ydbio.2004.11.010","article-title":"The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration","volume":"278","author":"Gurniak","year":"2005","journal-title":"Developmental Biology"},{"key":"10.1016\/j.gep.2010.12.003_b0075","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.ydbio.2009.03.027","article-title":"LIMK1 acts downstream of BMP signaling in developing retinal ganglion cell axons but not dendrites","volume":"330","author":"Hocking","year":"2009","journal-title":"Developmental Biology"},{"key":"10.1016\/j.gep.2010.12.003_b0080","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/bies.10402","article-title":"LIMK1 and CLIP-115: linking cytoskeletal defects to Williams syndrome","volume":"26","author":"Hoogenraad","year":"2004","journal-title":"BioEssays"},{"key":"10.1016\/j.gep.2010.12.003_b0085","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/emmm.200900003","article-title":"Induced chromosome deletions cause hypersociability and other features of Williams\u2013Beuren syndrome in mice","volume":"1","author":"Hua Li","year":"2009","journal-title":"EMBO Molecular Medicine"},{"key":"10.1016\/j.gep.2010.12.003_b0090","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1152\/ajprenal.2000.279.1.F65","article-title":"Metanephrogenic mesenchyme-to-epithelium transition induces profound expression changes of ion channels","volume":"279","author":"Huber","year":"2000","journal-title":"American Journal of Physiology-Renal Physiology"},{"key":"10.1016\/j.gep.2010.12.003_b0095","doi-asserted-by":"crossref","first-page":"2809","DOI":"10.1242\/dev.01858","article-title":"Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development","volume":"132","author":"Kobayashi","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.gep.2010.12.003_b0100","doi-asserted-by":"crossref","first-page":"1001176","DOI":"10.1371\/journal.pgen.1001176","article-title":"Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching","volume":"6","author":"Kuure","year":"2010","journal-title":"Morphogenesis PLoS Genet"},{"key":"10.1016\/j.gep.2010.12.003_b0105","doi-asserted-by":"crossref","first-page":"4792","DOI":"10.1038\/sj.emboj.7600418","article-title":"Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis","volume":"23","author":"Lee-Hoeflich","year":"2004","journal-title":"EMBO"},{"key":"10.1016\/j.gep.2010.12.003_b0110","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/ng.494","article-title":"Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin","volume":"42","author":"Mart\u00ednez-Estrada","year":"2010","journal-title":"Nature Genetics"},{"key":"10.1016\/j.gep.2010.12.003_b0115","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0896-6273(02)00758-4","article-title":"Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice","volume":"35","author":"Meng","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.gep.2010.12.003_b0120","first-page":"746","volume":"47","author":"Meng","year":"2004","journal-title":"Regulation of ADF\/cofilin phosphorylation and synaptic function by LIM-kinase neuropharmacology"},{"key":"10.1016\/j.gep.2010.12.003_b0125","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0169-328X(96)00257-4","article-title":"Comparison of tissue distribution of two novel serine\/threonine kinase genes containing the LIM motif (LIMK-1 and LIMK-2) in the developing rat","volume":"45","author":"Mori","year":"1997","journal-title":"Molecular Brain Research"},{"key":"10.1016\/j.gep.2010.12.003_b0130","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1242\/dev.01673","article-title":"Distinct developmental programs require different levels of Bmp signaling during mouse retinal development","volume":"132","author":"Murali","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.gep.2010.12.003_b0135","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/embor.2009.58","article-title":"Regulation of actin function by protein kinase A-mediated phosphorylation of Limk","volume":"10","author":"Nadella","year":"2009","journal-title":"EMBO Reports"},{"key":"10.1016\/j.gep.2010.12.003_b0140","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1242\/dev.010751","article-title":"ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells","volume":"135","author":"Pan","year":"2008","journal-title":"Development"},{"key":"10.1016\/j.gep.2010.12.003_b0145","doi-asserted-by":"crossref","unstructured":"L. Saxen, Organogenesis of the Kidney. Cambridge University Press, 1987.","DOI":"10.1017\/CBO9780511565083"},{"key":"10.1016\/j.gep.2010.12.003_b0150","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/nature04367","article-title":"A brain-specific microRNA regulates dendritic spine development","volume":"439","author":"Schratt","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.gep.2010.12.003_b0155","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s00109-007-0165-6","article-title":"LIM kinases: function, regulation and association with human disease","volume":"85","author":"Scott","year":"2007","journal-title":"Journal of Molecular Medicine"},{"key":"10.1016\/j.gep.2010.12.003_b0160","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1210\/er.2009-0016","article-title":"Steroidogenesis in the fetal testis and its susceptibility to disruption by exogenous compounds","volume":"30","author":"Scott","year":"2009","journal-title":"Endocrine Reviews"},{"key":"10.1016\/j.gep.2010.12.003_b0165","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.brainres.2007.07.090","article-title":"Early born lineage of retinal neurons express class III \u03b2-tubulin isotype","volume":"1176","author":"Sharma","year":"2007","journal-title":"Brain Research"},{"key":"10.1016\/j.gep.2010.12.003_b0170","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1091\/mbc.12.4.1131","article-title":"Cofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formation","volume":"12","author":"Toshima","year":"2001","journal-title":"Molecular Biology of the Cell"},{"key":"10.1016\/j.gep.2010.12.003_b0175","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1083\/jcb.200703055","article-title":"BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF\/cofilin","volume":"178","author":"Wen","year":"2007","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.gep.2010.12.003_b0180","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s004180050340","article-title":"Identification of renal podocytes in multiple species: higher vertebrates are vimentin positive\/lower vertebrates are desmin positive","volume":"111","author":"Yaoita","year":"1999","journal-title":"Histochemistry and Cell Biology"}],"container-title":["Gene Expression Patterns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567133X10001225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567133X10001225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T04:57:45Z","timestamp":1559883465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567133X10001225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":36,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S1567133X10001225"],"URL":"https:\/\/doi.org\/10.1016\/j.gep.2010.12.003","relation":{},"ISSN":["1567-133X"],"issn-type":[{"value":"1567-133X","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}