{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:58:17Z","timestamp":1760986697546,"version":"3.37.3"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100010449","name":"Ministry of Higher Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010449","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gene Expression Patterns"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.gep.2018.08.005","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T03:25:29Z","timestamp":1534994729000},"page":"49-54","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Expression pattern of delta-like 1 homolog in developing sympathetic neurons and chromaffin cells"],"prefix":"10.1016","volume":"30","author":[{"given":"Tehani","family":"El Faitwri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrin","family":"Huber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gep.2018.08.005_bib1","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/0092-8674(86)90823-8","article-title":"A bipotential neuroendocrine precursor whose choice of cell fate is determined by NGF and glucocorticoids","volume":"47","author":"Anderson","year":"1986","journal-title":"Cell"},{"key":"10.1016\/j.gep.2018.08.005_bib2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.mod.2012.09.010","article-title":"Conditional deletions refine the embryonic requirement for Dlk1","volume":"130","author":"Appelbe","year":"2013","journal-title":"Mech. Dev."},{"key":"10.1016\/j.gep.2018.08.005_bib3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.canlet.2011.11.032","article-title":"DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo","volume":"318","author":"Begum","year":"2012","journal-title":"Canc. Lett."},{"key":"10.1016\/j.gep.2018.08.005_bib4","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/nrm2009","article-title":"Notch signalling: a simple pathway becomes complex","volume":"7","author":"Bray","year":"2006","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.gep.2018.08.005_bib5","doi-asserted-by":"crossref","first-page":"71466","DOI":"10.18632\/oncotarget.12214","article-title":"Targeting endogenous DLK1 exerts antitumor effect on hepatocellular carcinoma through initiating cell differentiation","volume":"7","author":"Cai","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.gep.2018.08.005_bib6","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00441-017-2693-x","article-title":"From proliferation to target innervation: signaling molecules that direct sympathetic nervous system development","volume":"372","author":"Chan","year":"2018","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.gep.2018.08.005_bib7","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0070-2153(10)92003-6","article-title":"Canonical and non-canonical Notch ligands","volume":"92","author":"D'Souza","year":"2010","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.gep.2018.08.005_bib8","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1146\/annurev.pa.18.040178.002221","article-title":"Small intensely fluorescent (SIF) cells and nervous transmission in sympathetic ganglia","volume":"18","author":"Er\u00e4nk\u00f6","year":"1978","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.gep.2018.08.005_bib1a","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0925-4773(97)00135-4","article-title":"The developmental expression of choline acetyltransferase (ChAT) and the neuropeptide VIP in chick sympathetic neurons: evidence for different regulatory events in cholinergic differentiation","volume":"68","author":"Ernsberger","year":"1997","journal-title":"Mech. Dev."},{"key":"10.1016\/j.gep.2018.08.005_bib9","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/628962","article-title":"DLK1 protein expression during mouse development provides new insights into its function","volume":"2013","author":"Falix","year":"2013","journal-title":"ISRN Dev. Biol."},{"key":"10.1016\/j.gep.2018.08.005_bib10","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1677\/JOE-07-0242","article-title":"Cell and molecular biology of Notch","volume":"194","author":"Fi\u00faza","year":"2007","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.gep.2018.08.005_bib11","doi-asserted-by":"crossref","DOI":"10.1126\/science.aal3753","article-title":"Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla","volume":"357","author":"Furlan","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.gep.2018.08.005_bib12","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1159\/000015519","article-title":"Assignment of dlk (Dlk1) to mouse chromosome band 12E-F1 by in situ hybridization","volume":"88","author":"Gubina","year":"2000","journal-title":"Cytogenet. Cell Genet."},{"key":"10.1016\/j.gep.2018.08.005_bib13","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1159\/000015259","article-title":"Assignment of DLK1 to human chromosome band 14q32 by in situ hybridization","volume":"84","author":"Gubina","year":"1999","journal-title":"Cytogenet. Cell Genet."},{"key":"10.1016\/j.gep.2018.08.005_bib2a","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1242\/dev.02052","article-title":"Lack of an adrenal cortex in Sf1 mutant mice is compatible with the generation and differentiation of chromaffin cells","volume":"132","author":"Gut","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.gep.2018.08.005_bib14","first-page":"1","article-title":"Fetal antigen 1 (FA1) in the adult rat adrenal gland, ovary and pituitary gland","volume":"17","author":"Hedlund","year":"2003","journal-title":"In Vivo"},{"key":"10.1016\/j.gep.2018.08.005_bib15","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00441-014-1947-0","article-title":"Segregation of neuronal and neuroendocrine differentiation in the sympathoadrenal lineage","volume":"359","author":"Huber","year":"2015","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.gep.2018.08.005_bib16","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.ydbio.2006.07.010","article-title":"The sympathoadrenal cell lineage: specification, diversification, and new perspectives","volume":"298","author":"Huber","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.gep.2018.08.005_bib17","doi-asserted-by":"crossref","first-page":"4729","DOI":"10.1242\/dev.129.20.4729","article-title":"Development of chromaffin cells depends on MASH1 function","volume":"129","author":"Huber","year":"2002","journal-title":"Development"},{"key":"10.1016\/j.gep.2018.08.005_bib18","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ydbio.2005.01.007","article-title":"The role of Phox2B in chromaffin cell development","volume":"279","author":"Huber","year":"2005","journal-title":"Dev. Biol."},{"key":"10.1016\/j.gep.2018.08.005_bib20","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/oxfordjournals.humrep.a138110","article-title":"Studies on the isolation, structural analysis and tissue localization of fetal antigen 1 and its relation to a human adrenal-specific cDNA, pG2","volume":"8","author":"Jensen","year":"1993","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.gep.2018.08.005_bib21","doi-asserted-by":"crossref","first-page":"276","DOI":"10.4162\/nrp.2010.4.4.276","article-title":"Effect of retinoic acid and delta-like 1 homologue (DLK1) on differentiation in neuroblastoma","volume":"4","author":"Kim","year":"2010","journal-title":"Nutr. Res. Pract."},{"key":"10.1016\/j.gep.2018.08.005_bib22","doi-asserted-by":"crossref","first-page":"9271","DOI":"10.1158\/0008-5472.CAN-09-1605","article-title":"Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity","volume":"69","author":"Kim","year":"2009","journal-title":"Canc. Res."},{"key":"10.1016\/j.gep.2018.08.005_bib24","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0140-6736(96)90374-8","article-title":"Fetal antigen 1 and growth hormone in pituitary somatotroph cells","volume":"347","author":"Larsen","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.gep.2018.08.005_bib25","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0167-4781(95)00007-4","article-title":"dlk, pG2 and Pref-1 mRNAs encode similar proteins belonging to the EGF-like superfamily. Identification of polymorphic variants of this RNA","volume":"1261","author":"Lee","year":"1995","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.gep.2018.08.005_bib26","doi-asserted-by":"crossref","first-page":"4472","DOI":"10.1038\/sj.onc.1208637","article-title":"Expression of DLK1 in hematopoietic cells results in inhibition of differentiation and proliferation","volume":"24","author":"Li","year":"2005","journal-title":"Oncogene"},{"key":"10.1016\/j.gep.2018.08.005_bib27","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3324\/haematol.2012.070789","article-title":"Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells","volume":"98","author":"Mirshekar-Syahkal","year":"2013","journal-title":"Haematologica"},{"key":"10.1016\/j.gep.2018.08.005_bib28","doi-asserted-by":"crossref","first-page":"5585","DOI":"10.1128\/MCB.22.15.5585-5592.2002","article-title":"Mice lacking paternally expressed pref-1\/dlk1 display growth retardation and accelerated adiposity","volume":"22","author":"Moon","year":"2002","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.gep.2018.08.005_bib29","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ydbio.2006.03.008","article-title":"Delays in neuronal differentiation in Mash1\/Ascl1 mutants","volume":"295","author":"Pattyn","year":"2006","journal-title":"Dev. Biol."},{"key":"10.1016\/j.gep.2018.08.005_bib30","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/20700","article-title":"The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives","volume":"399","author":"Pattyn","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.gep.2018.08.005_bib32","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.1242\/dev.124.20.4065","article-title":"Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis","volume":"124","author":"Pattyn","year":"1997","journal-title":"Development"},{"key":"10.1016\/j.gep.2018.08.005_bib33","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1365-2826.2012.02367.x","article-title":"Cell loss and autophagy in the extra-adrenal chromaffin organ of Zuckerkandl are regulated by glucocorticoid signalling","volume":"25","author":"Schober","year":"2013","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.gep.2018.08.005_bib34","doi-asserted-by":"crossref","first-page":"9257","DOI":"10.1021\/bi00197a029","article-title":"Structural characterization and alternate splicing of the gene encoding the preadipocyte EGF-like protein pref-1","volume":"33","author":"Smas","year":"1994","journal-title":"Biochemistry"},{"key":"10.1016\/j.gep.2018.08.005_bib35","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/0092-8674(93)90252-L","article-title":"Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation","volume":"73","author":"Smas","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.gep.2018.08.005_bib36","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.mcn.2007.08.010","article-title":"Progenitor cell maintenance and neurogenesis in sympathetic ganglia involves Notch signaling","volume":"37","author":"Tsarovina","year":"2008","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.gep.2018.08.005_bib37","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00441-018-2796-z","article-title":"Origin and initiation mechanisms of neuroblastoma","volume":"372","author":"Tsubota","year":"2018","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.gep.2018.08.005_bib38","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/ijc.11047","article-title":"High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type","volume":"105","author":"van Limpt","year":"2003","journal-title":"Int. J. Canc."},{"key":"10.1016\/j.gep.2018.08.005_bib39","first-page":"317","article-title":"The function of the organs of Zuckerkandl","volume":"12","author":"West","year":"1953","journal-title":"Clin. Sci."},{"key":"10.1016\/j.gep.2018.08.005_bib40","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1158\/1535-7163.MCT-11-0531","article-title":"DLK1 as a potential target against cancer stem\/progenitor cells of hepatocellular carcinoma","volume":"11","author":"Xu","year":"2012","journal-title":"Mol. Canc. Therapeut."},{"key":"10.1016\/j.gep.2018.08.005_bib41","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1038\/sj.onc.1209219","article-title":"DLK1: increased expression in gliomas and associated with oncogenic activities","volume":"25","author":"Yin","year":"2006","journal-title":"Oncogene"},{"key":"10.1016\/j.gep.2018.08.005_bib42","doi-asserted-by":"crossref","first-page":"10355","DOI":"10.1074\/jbc.M111.312751","article-title":"Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration","volume":"287","author":"Zhu","year":"2012","journal-title":"J. Biol. Chem."}],"container-title":["Gene Expression Patterns"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567133X18301194?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567133X18301194?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T01:25:54Z","timestamp":1661822754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567133X18301194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":41,"alternative-id":["S1567133X18301194"],"URL":"https:\/\/doi.org\/10.1016\/j.gep.2018.08.005","relation":{},"ISSN":["1567-133X"],"issn-type":[{"type":"print","value":"1567-133X"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression pattern of delta-like 1 homolog in developing sympathetic neurons and chromaffin cells","name":"articletitle","label":"Article Title"},{"value":"Gene Expression Patterns","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gep.2018.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}