{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T21:14:46Z","timestamp":1761167686131,"version":"build-2065373602"},"reference-count":67,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"University of Gothenburg\/Sahlgrenska University Hospital","award":["ALFGBG-21611"],"award-info":[{"award-number":["ALFGBG-21611"]}]},{"name":"Wilhelm & Martina Lundgrens Vetenskapsfond","award":["VR 2008\u20132842"],"award-info":[{"award-number":["VR 2008\u20132842"]}]},{"name":"\u00c5ke Wibergs Stiftelse"},{"DOI":"10.13039\/501100005689","name":"G\u00f6teborg Medical Society","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005689","id-type":"DOI","asserted-by":"crossref"}]},{"name":"\u00c5hlens Stiftelse"},{"DOI":"10.13039\/501100006310","name":"Swedish Medical Research Council","doi-asserted-by":"crossref","award":["VR K2009-54X-21119-01-4","VR 2006\u20132783"],"award-info":[{"award-number":["VR K2009-54X-21119-01-4","VR 2006\u20132783"]}],"id":[{"id":"10.13039\/501100006310","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["30973240"],"award-info":[{"award-number":["30973240"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Growth Hormone &amp; IGF Research"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.ghir.2011.05.006","type":"journal-article","created":{"date-parts":[[2011,6,27]],"date-time":"2011-06-27T01:08:43Z","timestamp":1309136923000},"page":"205-211","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Safety aspects of longitudinal administration of IGF-I\/IGFBP-3 complex in neonatal mice"],"prefix":"10.1016","volume":"21","author":[{"given":"Gunnel","family":"Hellgren","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chatarina","family":"L\u00f6fqvist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Hagberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carina","family":"Mallard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Hellstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ghir.2011.05.006_bb0005","first-page":"558","article-title":"Insulin-like growth factors (IGF) 1 and 2 in human foetal plasma and relationship to gestational age and foetal size during midpregnancy","volume":"110","author":"Ashton","year":"1985","journal-title":"Acta. Endocrinol. (Copenh)"},{"key":"10.1016\/j.ghir.2011.05.006_bb0010","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1203\/00006450-199103000-00001","article-title":"Serum insulin-like growth factors and insulin-like growth factor binding proteins in the human fetus. Relationships with growth in normal subjects and in subjects with intrauterine growth retardation","volume":"29","author":"Lassarre","year":"1991","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ghir.2011.05.006_bb0015","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1111\/j.1651-2227.2007.00276.x","article-title":"Inflammation at birth and the insulin-like growth factor system in very preterm infants","volume":"96","author":"Hansen-Pupp","year":"2007","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.ghir.2011.05.006_bb0020","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1203\/01.PDR.0000155950.67503.BC","article-title":"The role of maternal factors, postnatal nutrition, weight gain, and gender in regulation of serum IGF-I among preterm infants","volume":"57","author":"Engstrom","year":"2005","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ghir.2011.05.006_bb0025","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1542\/peds.112.5.1016","article-title":"Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth","volume":"112","author":"Hellstrom","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0030","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1542\/peds.2005-1926","article-title":"Postnatal head growth deficit among premature infants parallels retinopathy of prematurity and insulin-like growth factor-1 deficit","volume":"117","author":"Lofqvist","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0035","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1111\/j.1469-7610.1997.tb01612.x","article-title":"Attention deficit hyperactivity disorders and other psychiatric outcomes in very low birthweight children at 12years","volume":"38","author":"Botting","year":"1997","journal-title":"J. Child Psychol. Psychiatry"},{"key":"10.1016\/j.ghir.2011.05.006_bb0040","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/j.1469-8749.1998.tb12324.x","article-title":"Cognitive and educational outcome of very-low-birthweight children in early adolescence","volume":"40","author":"Botting","year":"1998","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0045","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1542\/peds.113.1.e1","article-title":"Survival and long-term neurodevelopmental outcome of extremely premature infants born at 23\u201326weeks' gestational age at a tertiary center","volume":"113","author":"Hoekstra","year":"2004","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0050","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1542\/peds.105.6.1216","article-title":"Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993\u20131994","volume":"105","author":"Vohr","year":"2000","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0055","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1056\/NEJM200008103430601","article-title":"Neurologic and developmental disability after extremely preterm birth. EPICure Study Group","volume":"343","author":"Wood","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ghir.2011.05.006_bb0060","doi-asserted-by":"crossref","first-page":"e638","DOI":"10.1542\/peds.2008-2697","article-title":"Early weight gain predicts retinopathy in preterm infants: new, simple, efficient approach to screening","volume":"123","author":"Hellstrom","year":"2009","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0065","doi-asserted-by":"crossref","first-page":"5804","DOI":"10.1073\/pnas.101113998","article-title":"Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity","volume":"98","author":"Hellstrom","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ghir.2011.05.006_bb0070","doi-asserted-by":"crossref","first-page":"F17","DOI":"10.1136\/adc.2005.077438","article-title":"Are there critical periods for brain growth in children born preterm?","volume":"91","author":"Cooke","year":"2006","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"10.1016\/j.ghir.2011.05.006_bb0075","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.pneurobio.2003.08.002","article-title":"Insulin-like growth factor-1 and post-ischemic brain injury","volume":"70","author":"Guan","year":"2003","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0080","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1038\/sj.jp.7211594","article-title":"Hyperglycemia in extremely low birth weight infants in a predominantly Hispanic population and related morbidities","volume":"26","author":"Blanco","year":"2006","journal-title":"J. Perinatol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0085","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1159\/000088199","article-title":"Relationship between hyperglycemia and retinopathy of prematurity in very low birth weight infants","volume":"89","author":"Ertl","year":"2006","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.ghir.2011.05.006_bb0090","doi-asserted-by":"crossref","first-page":"F126","DOI":"10.1136\/adc.2008.154716","article-title":"Management of hyperglycaemia in the preterm infant","volume":"95","author":"Ogilvy-Stuart","year":"2010","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"10.1016\/j.ghir.2011.05.006_bb0095","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1530\/EJE-10-0752","article-title":"Impairment of insulin receptor signal transduction in placentas of intra-uterine growth-restricted newborns and its relationship with fetal growth","volume":"164","author":"Street","year":"2011","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0100","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1196\/annals.1367.027","article-title":"Birth weight, stress, and the metabolic syndrome in adult life","volume":"1083","author":"Phillips","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.ghir.2011.05.006_bb0105","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/00044067-200401000-00004","article-title":"Insulin resistance and hyperglycemia in critical illness: role of insulin in glycemic control","volume":"15","author":"Robinson","year":"2004","journal-title":"AACN Clin. Issues"},{"key":"10.1016\/j.ghir.2011.05.006_bb0110","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1471-2431-7-29","article-title":"A randomised controlled trial of early insulin therapy in very low birth weight infants, \u201cNIRTURE\u201d (neonatal insulin replacement therapy in Europe)","volume":"7","author":"Beardsall","year":"2007","journal-title":"BMC Pediatr."},{"key":"10.1016\/j.ghir.2011.05.006_bb0115","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1056\/NEJMoa0803725","article-title":"Early insulin therapy in very-low-birth-weight infants","volume":"359","author":"Beardsall","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ghir.2011.05.006_bb0120","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0022-3476(89)80797-8","article-title":"Insulin infusion with parenteral nutrition in extremely low birth weight infants with hyperglycemia","volume":"114","author":"Binder","year":"1989","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ghir.2011.05.006_bb0125","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0022-3476(05)82212-7","article-title":"A controlled trial of insulin infusion and parenteral nutrition in extremely low birth weight infants with glucose intolerance","volume":"118","author":"Collins","year":"1991","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ghir.2011.05.006_bb0130","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1542\/peds.78.4.625","article-title":"Insulin pump therapy in the very low birth weight infant","volume":"78","author":"Ostertag","year":"1986","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0135","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0014-4886(03)00032-3","article-title":"Quantitative analysis of perinatal rodent oligodendrocyte lineage progression and its correlation with human","volume":"181","author":"Craig","year":"2003","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0140","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1651-2227.1997.tb18353.x","article-title":"Hypoxia\u2013ischaemia model in the 7-day-old rat: possibilities and shortcomings","volume":"422","author":"Hagberg","year":"1997","journal-title":"Acta Paediatr. Suppl."},{"key":"10.1016\/j.ghir.2011.05.006_bb0145","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1167\/iovs.10-5176","article-title":"The mouse retina as an angiogenesis model","volume":"51","author":"Stahl","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"Suppl. 1","key":"10.1016\/j.ghir.2011.05.006_bb0150","first-page":"11","article-title":"Radioimmunoassays for IGFs and IGFBPs","volume":"4","author":"Blum","year":"1994","journal-title":"Growth Regul."},{"key":"10.1016\/j.ghir.2011.05.006_bb0155","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1677\/joe.0.1490379","article-title":"Characterization of serum-derived and recombinant rat IGF-I and their use for measuring true concentrations of IGF-I in rat plasma","volume":"149","author":"Upton","year":"1996","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0160","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1046\/j.1471-4159.2003.01838.x","article-title":"Activation of ERK1\/2 after neonatal rat cerebral hypoxia\u2013ischaemia","volume":"86","author":"Wang","year":"2003","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ghir.2011.05.006_bb0165","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1097\/01.jnen.0000263870.91811.6f","article-title":"Dual role of intrauterine immune challenge on neonatal and adult brain vulnerability to hypoxia\u2013ischemia","volume":"66","author":"Wang","year":"2007","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0170","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1177\/0883073809338068","article-title":"White matter damage after chronic subclinical inflammation in newborn mice","volume":"24","author":"Wang","year":"2009","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0175","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/ana.21066","article-title":"N-acetylcysteine reduces lipopolysaccharide-sensitized hypoxic\u2013ischemic brain injury","volume":"61","author":"Wang","year":"2007","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0180","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1161\/01.STR.0000254729.27386.05","article-title":"Maturation-dependent vulnerability of perinatal white matter in premature birth","volume":"38","author":"Back","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.ghir.2011.05.006_bb0185","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1203\/PDR.0b013e3181973dc8","article-title":"Oxygen-induced retinopathy in mice: amplification by neonatal IGF-I deficit and attenuation by IGF-I administration","volume":"65","author":"Vanhaesebrouck","year":"2009","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ghir.2011.05.006_bb0190","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0003-9969(00)00057-1","article-title":"Effects of insulin-like growth factor-I on nasopremaxillary growth under different masticatory loadings in growing mice","volume":"45","author":"Tokimasa","year":"2000","journal-title":"Arch. Oral Biol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0195","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1365-2362.1995.tb01958.x","article-title":"The effect of recombinant human IGF-I on protein metabolism in post-operative patients without nutrition compared to effects in experimental animals","volume":"25","author":"Sandstrom","year":"1995","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1016\/j.ghir.2011.05.006_bb0200","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0969-9961(03)00106-2","article-title":"Insulin-like growth factor-I improves cerebellar dysfunction but does not prevent cerebellar neurodegeneration in the calcium channel mutant mouse, leaner","volume":"14","author":"Nahm","year":"2003","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.ghir.2011.05.006_bb0205","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1111\/j.1460-9568.2005.03982.x","article-title":"IGF-I neuroprotection in the immature brain after hypoxia\u2013ischemia, involvement of Akt and GSK3beta?","volume":"21","author":"Brywe","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ghir.2011.05.006_bb0210","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brainres.2005.09.042","article-title":"IGF-1 protects oligodendrocyte progenitor cells and improves neurological functions following cerebral hypoxia\u2013ischemia in the neonatal rat","volume":"1063","author":"Lin","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.ghir.2011.05.006_bb0215","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.expneurol.2009.03.021","article-title":"Intranasal administration of IGF-1 attenuates hypoxic\u2013ischemic brain injury in neonatal rats","volume":"217","author":"Lin","year":"2009","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0220","doi-asserted-by":"crossref","first-page":"e584","DOI":"10.1542\/peds.2009-0449","article-title":"Early hyperglycemia is a risk factor for death and white matter reduction in preterm infants","volume":"125","author":"Alexandrou","year":"2010","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0225","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1542\/peds.53.2.189","article-title":"Glucose intolerance in infants of very low birth weight. I. Incidence of hyperglycemia in infants of birth weights 1100 grams or less","volume":"53","author":"Dweck","year":"1974","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0230","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1159\/000014027","article-title":"Hyperglycemia in extremely- low-birth-weight infants","volume":"74","author":"Meetze","year":"1998","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.ghir.2011.05.006_bb0235","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1159\/000083863","article-title":"Continuous insulin infusion in hyperglycaemic extremely-low-birth-weight neonates","volume":"87","author":"Ng","year":"2005","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.ghir.2011.05.006_bb0240","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1542\/peds.2005-1819","article-title":"Association of hypoglycemia, hyperglycemia, and glucose variability with morbidity and death in the pediatric intensive care unit","volume":"118","author":"Wintergerst","year":"2006","journal-title":"Pediatrics"},{"doi-asserted-by":"crossref","unstructured":"K. Beardsall, S. Vanhaesebrouck, A.L. Ogilvy-Stuart, et al., Prevalence and determinants of hyperglycemia in very low birth weight infants: cohort analyses of the NIRTURE study, J Pediatr 157 (2010) 715\u2013719 e711-713.","key":"10.1016\/j.ghir.2011.05.006_bb0245","DOI":"10.1016\/j.jpeds.2010.04.032"},{"key":"10.1016\/j.ghir.2011.05.006_bb0250","article-title":"Interventions for treatment of neonatal hyperglycemia in very low birth weight infants","author":"Bottino","year":"2009","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.ghir.2011.05.006_bb0255","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/00005237-199912000-00007","article-title":"Continuous insulin intravenous infusion therapy for VLBW infants","volume":"13","author":"Ditzenberger","year":"1999","journal-title":"J. Perinat. Neonatal Nurs."},{"key":"10.1016\/j.ghir.2011.05.006_bb0260","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1053\/j.sempedsurg.2008.07.007","article-title":"Stress and pain relief in the care of the surgical neonate","volume":"17","author":"Currie","year":"2008","journal-title":"Semin. Pediatr. Surg."},{"key":"10.1016\/j.ghir.2011.05.006_bb0265","first-page":"E118","article-title":"Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in mice","volume":"275","author":"Bark","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0270","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0955-2235(95)00003-8","article-title":"Pharmacokinetics and bioavailability of rhIGF-I\/IGFBP-3 in the rat and monkey","volume":"6","author":"Adams","year":"1995","journal-title":"Prog. Growth Factor Res."},{"key":"10.1016\/j.ghir.2011.05.006_bb0275","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1210\/jc.2008-1293","article-title":"Fresh\u2013frozen plasma as a source of exogenous insulin-like growth factor-I in the extremely preterm infant","volume":"94","author":"Hansen-Pupp","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2011.05.006_bb0280","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1203\/PDR.0b013e31819d9e8c","article-title":"A pharmacokinetic and dosing study of intravenous insulin-like growth factor-I and IGF-binding protein-3 complex to preterm infants","volume":"65","author":"Lofqvist","year":"2009","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ghir.2011.05.006_bb0285","article-title":"New insights into the development of retinopathy of prematurity \u2014 importance of early weight gain","author":"Hellstrom","year":"2009","journal-title":"Acta Paediatr."},{"key":"10.1016\/j.ghir.2011.05.006_bb0290","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1001\/archopht.124.12.1711","article-title":"Longitudinal postnatal weight and insulin-like growth factor I measurements in the prediction of retinopathy of prematurity","volume":"124","author":"Lofqvist","year":"2006","journal-title":"Arch. Ophthalmol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0295","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/jp.2009.142","article-title":"Improved weight attainment of extremely low-gestational-age infants with bronchopulmonary dysplasia","volume":"30","author":"Madden","year":"2010","journal-title":"J. Perinatol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0300","doi-asserted-by":"crossref","first-page":"3413","DOI":"10.1210\/jcem.87.7.8629","article-title":"IGF-I is critical for normal vascularization of the human retina","volume":"87","author":"Hellstrom","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2011.05.006_bb0305","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1210\/en.2006-1701","article-title":"Fetal and amniotic insulin-like growth factor-I supplements improve growth rate in intrauterine growth restriction fetal sheep","volume":"148","author":"Eremia","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.ghir.2011.05.006_bb0310","first-page":"R1148","article-title":"Insulin-like growth factor I promotes growth selectively in fetal sheep in late gestation","volume":"270","author":"Lok","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ghir.2011.05.006_bb0315","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1071\/RD02022","article-title":"A chronic low dose infusion of insulin-like growth factor I alters placental function but does not affect fetal growth","volume":"14","author":"Bloomfield","year":"2002","journal-title":"Reprod. Fertil. Dev."},{"key":"10.1016\/j.ghir.2011.05.006_bb0320","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.jcomdis.2009.03.007","article-title":"Magnetic resonance imaging \u2014 insights into brain injury and outcomes in premature infants","volume":"42","author":"Mathur","year":"2009","journal-title":"J. Commun. Disord."},{"key":"10.1016\/j.ghir.2011.05.006_bb0325","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1542\/peds.2005-1866","article-title":"Natural history of brain lesions in extremely preterm infants studied with serial magnetic resonance imaging from birth and neurodevelopmental assessment","volume":"118","author":"Dyet","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.ghir.2011.05.006_bb0330","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1172\/JCI118416","article-title":"Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic\u2013ischemic injury in fetal lambs","volume":"97","author":"Johnston","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ghir.2011.05.006_bb0335","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1203\/PDR.0b013e3181dc240f","article-title":"IGF-1 can either protect against or increase LPS-induced damage in the developing rat brain","volume":"67","author":"Pang","year":"2010","journal-title":"Pediatr. Res."}],"container-title":["Growth Hormone &amp; IGF Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637411000566?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637411000566?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:46:33Z","timestamp":1761086793000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096637411000566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":67,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S1096637411000566"],"URL":"https:\/\/doi.org\/10.1016\/j.ghir.2011.05.006","relation":{},"ISSN":["1096-6374"],"issn-type":[{"type":"print","value":"1096-6374"}],"subject":[],"published":{"date-parts":[[2011,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Safety aspects of longitudinal administration of IGF-I\/IGFBP-3 complex in neonatal mice","name":"articletitle","label":"Article Title"},{"value":"Growth Hormone & IGF Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ghir.2011.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}