{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T21:16:37Z","timestamp":1761167797128,"version":"build-2065373602"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Heartland Genetics Collaborative"},{"name":"NICHD","award":["HD02528"],"award-info":[{"award-number":["HD02528"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Growth Hormone & IGF Research"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.ghir.2017.12.001","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T04:54:05Z","timestamp":1512536045000},"page":"29-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Growth hormone receptor (GHR) gene polymorphism and scoliosis in Prader-Willi syndrome"],"prefix":"10.1016","volume":"39","author":[{"given":"Merlin G.","family":"Butler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waheeda","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maaz","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann M.","family":"Manzardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ghir.2017.12.001_bb0005","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/ajmg.1320350306","article-title":"Prader-Willi syndrome: current understanding of cause and diagnosis","volume":"35","author":"Butler","year":"1990","journal-title":"Am. J. Med. Genet."},{"year":"2006","series-title":"Management of Prader-Willi Syndrome","author":"Butler","key":"10.1016\/j.ghir.2017.12.001_bb0010"},{"key":"10.1016\/j.ghir.2017.12.001_bb0015","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/gim.0b013e31822bead0","article-title":"Prader-Willi syndrome","volume":"14","author":"Cassidy","year":"2012","journal-title":"Genet. Med."},{"key":"10.1016\/j.ghir.2017.12.001_bb0020","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/sj.ejhg.5201716","article-title":"Changing rates of genetic subtypes of Prader-Willi syndrome in the UK","volume":"15","author":"Whittington","year":"2007","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.ghir.2017.12.001_bb0025","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1016\/S0140-6736(83)92745-9","article-title":"Parental origin of chromosome 15 deletion in Prader-Willi syndrome","volume":"1","author":"Butler","year":"1983","journal-title":"Lancet"},{"key":"10.1016\/j.ghir.2017.12.001_bb0030","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1007\/s40618-015-0312-9","article-title":"Prader-Willi syndrome: a review of clinical, genetic, and endocrine findings","volume":"38","author":"Angulo","year":"2015","journal-title":"J. Endocrinol. Investig."},{"key":"10.1016\/j.ghir.2017.12.001_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/bs.pmbts.2015.12.003","article-title":"Single gene and syndromic causes of obesity: illustrative examples","volume":"140","author":"Butler","year":"2016","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"key":"10.1016\/j.ghir.2017.12.001_bb0040","article-title":"Prader-Willi syndrome: clinical aspects","volume":"473941","author":"Elena","year":"2012","journal-title":"J. Obes."},{"key":"10.1016\/j.ghir.2017.12.001_bb0045","first-page":"279","article-title":"Auxological and endocrine evolution of 28 children with Prader-Willi syndrome: effect of GH therapy in 14 children","volume":"53","author":"Tauber","year":"2000","journal-title":"Horm. Res."},{"key":"10.1016\/j.ghir.2017.12.001_bb0050","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1002\/ajmg.a.35378","article-title":"Growth hormone secretion and its effect on height in pediatric patients with different genotypes of Prader-Willi syndrome","volume":"158A","author":"Oto","year":"2012","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.ghir.2017.12.001_bb0055","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1651-2227.1999.tb14416.x","article-title":"Five years of growth hormone treatment in children with Prader-Willi syndrome","volume":"433","author":"Lindgren","year":"1999","journal-title":"Acta Paediatr. Suppl."},{"key":"10.1016\/j.ghir.2017.12.001_bb0060","first-page":"200","article-title":"Body composition abnormalities in children with Prader-Willi syndrome and long-term effects of growth hormone therapy","volume":"53","author":"Eiholzer","year":"2000","journal-title":"Horm. Res."},{"key":"10.1016\/j.ghir.2017.12.001_bb0065","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1210\/jc.2009-1389","article-title":"Long-term growth hormone therapy changes the natural history of body composition and motor function in children with Prader-Willi syndrome","volume":"95","author":"Carrel","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2017.12.001_bb0070","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ghir.2013.01.001","article-title":"Effects of growth hormone treatment in adults with Prader-Willi syndrome","volume":"23","author":"Butler","year":"2013","journal-title":"Growth Hormon. IGF Res."},{"key":"10.1016\/j.ghir.2017.12.001_bb0075","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1067\/mpd.2000.105369","article-title":"Sustained benefit after 2years of growth hormone on body composition, fat utilization, physical strength and agility, and growth in Prader-Willi syndrome","volume":"137","author":"Myers","year":"2000","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ghir.2017.12.001_bb0080","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1177\/0009922815617973","article-title":"Growth charts for Prader-Willi syndrome during growth hormone treatment","volume":"55","author":"Butler","year":"2016","journal-title":"Clin. Pediatr."},{"key":"10.1016\/j.ghir.2017.12.001_bb0085","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1097\/BRS.0b013e318163fa24","article-title":"Complications of scoliosis surgery in Prader-Willi syndrome","volume":"33","author":"Accadbled","year":"2008","journal-title":"Spine"},{"key":"10.1016\/j.ghir.2017.12.001_bb0090","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00776-014-0651-y","article-title":"The characteristics of scoliosis in Prader-Willi syndrome (PWS): analysis of 58 scoliosis patients with PWS","volume":"20","author":"Nakamura","year":"2015","journal-title":"J. Orthop. Sci."},{"key":"10.1016\/j.ghir.2017.12.001_bb0095","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1038\/ng1379","article-title":"A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone","volume":"36","author":"Dos Santos","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ghir.2017.12.001_bb0100","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/j.1365-2265.2011.04207.x","article-title":"The growth hormone receptor gene deleted for exon three (GHRd3) polymorphism is associated with birth and placental weight","volume":"76","author":"Padidela","year":"2012","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.ghir.2017.12.001_bb0105","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1002\/ajmg.a.35980","article-title":"Growth hormone receptor (GHR) gene polymorphism and Prader-Willi syndrome","volume":"161A","author":"Butler","year":"2013","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1016\/j.ghir.2017.12.001_bb0110","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/BPO.0b013e3181da857d","article-title":"The musculoskeletal manifestations of Prader-Willi syndrome","volume":"30","author":"Shim","year":"2010","journal-title":"J. Pediatr. Orthop."},{"key":"10.1016\/j.ghir.2017.12.001_bb0115","doi-asserted-by":"crossref","first-page":"4895","DOI":"10.1210\/jc.2016-2163","article-title":"Effect of genotype and previous GH treatment on adiposity in adults with Prader-Willi syndrome","volume":"101","author":"Coupaye","year":"2016","journal-title":"J. Clin. Endocrinol. Metab."}],"container-title":["Growth Hormone & IGF Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637417301107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637417301107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:50:35Z","timestamp":1761087035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096637417301107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":23,"alternative-id":["S1096637417301107"],"URL":"https:\/\/doi.org\/10.1016\/j.ghir.2017.12.001","relation":{},"ISSN":["1096-6374"],"issn-type":[{"type":"print","value":"1096-6374"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Growth hormone receptor (GHR) gene polymorphism and scoliosis in Prader-Willi syndrome","name":"articletitle","label":"Article Title"},{"value":"Growth Hormone & IGF Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ghir.2017.12.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}