{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T20:33:14Z","timestamp":1788294794116,"version":"build-2803163510"},"reference-count":17,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Growth Hormone &amp; IGF Research"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.ghir.2020.101361","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T21:21:48Z","timestamp":1602883308000},"page":"101361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["The inter \u2013 Test variability of growth hormone stimulation tests and factors affecting this variability"],"prefix":"10.1016","volume":"55","author":[{"given":"Eyal Ben","family":"Dori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmit","family":"Avnon Ziv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adi","family":"Auerbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yael","family":"Greenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hagit","family":"Zaken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Floris","family":"Levy-Khademi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ghir.2020.101361_bb0005","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0022-3476(94)70117-2","article-title":"Utah growth study: growth standards and the prevalence of growth hormone deficiency","volume":"125","author":"Lindsay","year":"1994","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ghir.2020.101361_bb0010","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1136\/bmj.2.6084.427","article-title":"Prevalence of severe growth hormone deficiency","volume":"2","author":"Vimpani","year":"1977","journal-title":"Br. Med. J."},{"key":"10.1016\/j.ghir.2020.101361_bb0015","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1136\/adc.52.3.197","article-title":"Aetiology of idiopathic growth hormone deficiency in England and Wales","volume":"52","author":"Rona","year":"1977","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.ghir.2020.101361_bb0020","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1159\/000452150","article-title":"Guidelines for growth hormone and insulin-like growth factor-I treatment in children and adolescents\u202f: growth hormone deficiency, idiopathic short stature, and primary insulin-like growth factor-I deficiency","author":"Grimberg","year":"2016","journal-title":"Horm. Res. Paediatr."},{"key":"10.1016\/j.ghir.2020.101361_bb0025","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1054\/ghir.2001.0203","article-title":"Diagnosis and management of growth hormone deficiency in childhood and adolescence. Part 1: diagnosis of growth hormone deficiency","volume":"11","author":"Sizonenko","year":"2001","journal-title":"Growth Hormon. IGF Res."},{"key":"10.1016\/j.ghir.2020.101361_bb0030","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1136\/archdischild-2014-307228","article-title":"Controversies in the diagnosis and management of growth hormone deficiency in childhood and adolescence","volume":"101","author":"Murray","year":"2016","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.ghir.2020.101361_bb0035","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1210\/jcem-71-1-230","article-title":"Variability of growth hormone response to pharmacological and sleep tests performed twice in short children","volume":"71","author":"Tassoni","year":"1990","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2020.101361_bb0040","first-page":"3323","article-title":"Reliability of provocative tests to assess growth hormone secretory status. Study in 472 normally growing children","volume":"81","author":"Ghigo","year":"1996","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2020.101361_bb0045","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/cen.13845","article-title":"Reliability of clonidine testing for the diagnosis of growth hormone deficiency in children and adolescents","volume":"89","author":"Ibba","year":"2018","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.ghir.2020.101361_bb0050","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1067\/mpd.2002.122729","article-title":"Results of early reevaluation of growth hormone secretion in short children with apparent growth hormone deficiency","volume":"140","author":"Loche","year":"2002","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ghir.2020.101361_bb0055","doi-asserted-by":"crossref","first-page":"4251","DOI":"10.1210\/jc.2009-0779","article-title":"The glucagon test in the diagnosis of growth hormone deficiency in children with short stature younger than 6 years","volume":"94","author":"Secco","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2020.101361_bb0060","first-page":"557","article-title":"The assessment of growth hormone status in normal young adult males using a variety of provocative agents","volume":"45","author":"Rahim","year":"1996","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2020.101361_bb0065","first-page":"336","article-title":"Endogenous growth hormone secretion and clearance rates in normal boys, as determined by deconvolution analysis: relationship to age, pubertal status, and body mass","volume":"74","author":"Martha","year":"1992","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2020.101361_bb0070","doi-asserted-by":"crossref","first-page":"4875","DOI":"10.1210\/jc.2009-1369","article-title":"Effect of body mass index on peak growth hormone response to provocative testing in children with short stature","volume":"94","author":"Stanley","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2020.101361_bb0075","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.3346\/jkms.2013.28.9.1351","article-title":"Influence of body mass index on the growth hormone response to provocative testing in short children without growth hormone deficiency","volume":"28","author":"Lee","year":"2013","journal-title":"J. Korean Med. Sci."},{"key":"10.1016\/j.ghir.2020.101361_bb0080","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1111\/j.1365-2265.2011.03988.x","article-title":"Effect of body mass index on the growth hormone response to clonidine stimulation testing in children with short stature","volume":"74","author":"Loche","year":"2011","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.ghir.2020.101361_bb0085","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1530\/eje.1.01967","article-title":"The cut-off limits of the GH response to GH-releasing hormone-arginine test related to body mass index","volume":"153","author":"Corneli","year":"2005","journal-title":"Eur. J. Endocrinol."}],"container-title":["Growth Hormone &amp; IGF Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637420300708?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637420300708?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:52:50Z","timestamp":1761087170000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096637420300708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":17,"alternative-id":["S1096637420300708"],"URL":"https:\/\/doi.org\/10.1016\/j.ghir.2020.101361","relation":{},"ISSN":["1096-6374"],"issn-type":[{"value":"1096-6374","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The inter \u2013 Test variability of growth hormone stimulation tests and factors affecting this variability","name":"articletitle","label":"Article Title"},{"value":"Growth Hormone & IGF Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ghir.2020.101361","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101361"}}