{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T02:58:53Z","timestamp":1794020333226,"version":"4.8.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Growth Hormone &amp; IGF Research"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ghir.2023.101531","type":"journal-article","created":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T19:31:29Z","timestamp":1677267089000},"page":"101531","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Comparison of growth response and adverse reaction according to growth hormone dosing strategy for children with short stature: LG Growth Study"],"prefix":"10.1016","volume":"69-70","author":[{"given":"Kyungchul","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mo Kyung","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Suk","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han Saem","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeongseob","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junghwan","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahreum","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Wook","family":"Chae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho-Seong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ghir.2023.101531_bb0005","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1210\/jcem-18-8-901","article-title":"Treatment of a pituitary dwarf with human growth hormone","volume":"18","author":"Raben","year":"1958","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2023.101531_bb0010","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1159\/000452150","article-title":"Guidelines for growth hormone and insulin-like growth factor-I treatment in children and adolescents: growth hormone deficiency, idiopathic short stature, and primary insulin-like growth factor-I deficiency","volume":"86","author":"Grimberg","year":"2016","journal-title":"Horm Res Paediatr."},{"key":"10.1016\/j.ghir.2023.101531_bb0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0181567","article-title":"Growth hormone prescribing and initial BMI SDS: increased biochemical adverse effects and costs in obese children without additional gain in height","volume":"12","author":"Hawcutt","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.ghir.2023.101531_bb0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0216927","article-title":"Long-term safety and effectiveness of growth hormone therapy in Korean children with growth disorders: 5-year results of LG Growth Study","volume":"14","author":"Rhie","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ghir.2023.101531_bb0025","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/cen.12315","article-title":"Comparison of weight- vs body surface area-based growth hormone dosing for children: implications for response","volume":"80","author":"Hughes","year":"2014","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.ghir.2023.101531_bb0030","first-page":"233","article-title":"European audit of current practice in diagnosis and treatment of childhood growth hormone deficiency","volume":"58","author":"Juul","year":"2002","journal-title":"Horm. Res."},{"key":"10.1016\/j.ghir.2023.101531_bb0035","doi-asserted-by":"crossref","first-page":"647","DOI":"10.3181\/00379727-82-20206","article-title":"Total body water and blood volume in hereditary obese-hyperglycemic syndrome of mice","volume":"82","author":"Mayer","year":"1953","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.ghir.2023.101531_bb0040","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/S0026-0495(98)90075-0","article-title":"Growth hormone bioactivity, insulin-like growth factors (IGFs), and IGF binding proteins in obese children","volume":"47","author":"Radetti","year":"1998","journal-title":"Metabolism."},{"key":"10.1016\/j.ghir.2023.101531_bb0045","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1038\/sj.clpt.6100381","article-title":"Dosing in obesity: a simple solution to a big problem","volume":"82","author":"Han","year":"2007","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.ghir.2023.101531_bb0050","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1530\/EJE-17-0430","article-title":"Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting","volume":"177","author":"Gravholt","year":"2017","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.ghir.2023.101531_bb0055","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3803\/EnM.2017.32.1.144","article-title":"Corrigendum: correction of acknowledgments: epidemiology of childhood obesity in Korea","volume":"32","author":"Ha","year":"2017","journal-title":"Endocrinol. Metab. (Seoul)."},{"key":"10.1016\/j.ghir.2023.101531_bb0060","doi-asserted-by":"crossref","first-page":"43","DOI":"10.6065\/apem.2018.23.1.43","article-title":"Design of the long-term observational cohort study with recombinant human growth hormone in Korean children: LG Growth Study","volume":"23","author":"Chung","year":"2018","journal-title":"Ann. Pediatr. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2023.101531_bb0065","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.metabol.2005.11.004","article-title":"Body surface area in normal-weight, overweight, and obese adults. A comparison study","volume":"55","author":"Verbraecken","year":"2006","journal-title":"Metabolism."},{"key":"10.1016\/j.ghir.2023.101531_bb0070","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3345\/kjp.2018.61.5.135","article-title":"The 2017 Korean National Growth Charts for children and adolescents: development, improvement, and prospects","volume":"61","author":"Kim","year":"2018","journal-title":"Korean J. Pediatr."},{"key":"10.1016\/j.ghir.2023.101531_bb0075","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.clinbiochem.2011.10.003","article-title":"Reference values for serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Korean children and adolescents","volume":"45","author":"Hyun","year":"2012","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.ghir.2023.101531_bb0080","first-page":"53","article-title":"Radiographic atlas of skeletal development of the hand and wrist: second edition","volume":"91","author":"Bayer","year":"1959","journal-title":"Calif. Med."},{"key":"10.1016\/j.ghir.2023.101531_bb0085","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1210\/jc.2008-0509","article-title":"Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop","volume":"93","author":"Cohen","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2023.101531_bb0090","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1210\/jc.2006-2017","article-title":"Management of the child born small for gestational age through to adulthood: a consensus statement of the International Societies of Pediatric Endocrinology and the Growth Hormone Research Society","volume":"92","author":"Clayton","year":"2007","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2023.101531_bb0095","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/s41581-019-0161-4","article-title":"Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease","volume":"15","author":"Drube","year":"2019","journal-title":"Nat. Rev. Nephrol."},{"issue":"Suppl. 3","key":"10.1016\/j.ghir.2023.101531_bb0100","first-page":"153","article-title":"Safety of growth hormone treatment in children born small for gestational age: the US trial and KIGS analysis","volume":"65","author":"Cutfield","year":"2006","journal-title":"Horm. Res."},{"key":"10.1016\/j.ghir.2023.101531_bb0105","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1159\/000357844","article-title":"Comparison of body surface area versus weight-based growth hormone dosing for girls with Turner syndrome","volume":"81","author":"Schrier","year":"2014","journal-title":"Horm. Res. Paediatr."},{"key":"10.1016\/j.ghir.2023.101531_bb0110","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1210\/jc.2002-021172","article-title":"Adult height after long-term, continuous growth hormone (GH) treatment in short children born small for gestational age: results of a randomized, double-blind, dose-response GH trial","volume":"88","author":"Van Pareren","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2023.101531_bb0115","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000281323","article-title":"Adult height in children with growth hormone deficiency: a randomized, controlled, growth hormone dose-response trial","volume":"74","author":"Sas","year":"2010","journal-title":"Horm. Res. Paediatr."},{"key":"10.1016\/j.ghir.2023.101531_bb0120","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1210\/jc.2008-0707","article-title":"Dose-dependent effect of growth hormone on final height in children with short stature without growth hormone deficiency","volume":"93","author":"Albertsson-Wikland","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2023.101531_bb0125","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1365-2265.2011.03937.x","article-title":"Growth hormone treatment for Turner syndrome in Australia reveals that younger age and increased dose interact to improve response","volume":"74","author":"Hughes","year":"2011","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.ghir.2023.101531_bb0130","doi-asserted-by":"crossref","first-page":"5197","DOI":"10.1210\/jc.2005-0470","article-title":"Adult height and pubertal growth in Turner syndrome after treatment with recombinant growth hormone","volume":"90","author":"Soriano-Guillen","year":"2005","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2023.101531_bb0135","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s11102-007-0027-9","article-title":"IGF-I measurements in the monitoring of GH therapy","volume":"10","author":"Higham","year":"2007","journal-title":"Pituitary."},{"key":"10.1016\/j.ghir.2023.101531_bb0140","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/anae.12860","article-title":"An aid to drug dosing safety in obese children: development of a new nomogram and comparison with existing methods for estimation of ideal body weight and lean body mass","volume":"70","author":"Callaghan","year":"2015","journal-title":"Anaesthesia."},{"key":"10.1016\/j.ghir.2023.101531_bb0145","series-title":"The Growth of the Surface Area of the Human Body","author":"Boyd","year":"1935"},{"key":"10.1016\/j.ghir.2023.101531_bb0150","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1016\/j.clinthera.2015.05.495","article-title":"Pediatric obesity: pharmacokinetics and implications for drug dosing","volume":"37","author":"Kendrick","year":"2015","journal-title":"Clin. Ther."},{"key":"10.1016\/j.ghir.2023.101531_bb0155","first-page":"94","article-title":"Pharmacokinetics and drug dosing in obese children","volume":"15","author":"Kendrick","year":"2010","journal-title":"J. Pediatr. Pharmacol. Ther."}],"container-title":["Growth Hormone &amp; IGF Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637423000096?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637423000096?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T22:53:12Z","timestamp":1761087192000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096637423000096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":31,"alternative-id":["S1096637423000096"],"URL":"https:\/\/doi.org\/10.1016\/j.ghir.2023.101531","relation":{},"ISSN":["1096-6374"],"issn-type":[{"value":"1096-6374","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of growth response and adverse reaction according to growth hormone dosing strategy for children with short stature: LG Growth Study","name":"articletitle","label":"Article Title"},{"value":"Growth Hormone & IGF Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ghir.2023.101531","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101531"}}