{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T01:25:52Z","timestamp":1776648352130,"version":"3.51.2"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Growth Hormone &amp; IGF Research"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.ghir.2024.101606","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T18:11:15Z","timestamp":1719943875000},"page":"101606","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Association of circulating leptin, growth hormone, and ghrelin with fibromyalgia: A meta-analysis"],"prefix":"10.1016","volume":"77","author":[{"given":"Young Ho","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwan Gyu","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ghir.2024.101606_bb0005","first-page":"1","article-title":"Fibromyalgia","volume":"1","author":"H\u00e4user","year":"2015","journal-title":"Nat. Rev. Dis. Prim."},{"key":"10.1016\/j.ghir.2024.101606_bb0010","doi-asserted-by":"crossref","first-page":"126","DOI":"10.4078\/jrd.2021.28.3.126","article-title":"Neuropathic pain and its relationship with fibromyalgia, vitamin D status and medication use in patients with ankylosing spondylitis","volume":"28","author":"M\u0131zrak","year":"2021","journal-title":"J. Rheum. Dis."},{"key":"10.1016\/j.ghir.2024.101606_bb0015","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4078\/jrd.2022.29.1.4","article-title":"Disentangling diagnosis and Management of Fibromyalgia","volume":"29","author":"Kang","year":"2022","journal-title":"J. Rheum. Dis."},{"key":"10.1016\/j.ghir.2024.101606_bb0020","doi-asserted-by":"crossref","first-page":"T1","DOI":"10.1530\/JOE-14-0405","article-title":"Leptin at 20: an overview","volume":"223","author":"Friedman","year":"2014","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ghir.2024.101606_bb0025","first-page":"102","article-title":"The relationship between serum leptin level and disease activity and inflammatory markers in fibromyalgia patients","volume":"5","author":"Ataoglu","year":"2018","journal-title":"Northern Clin. Istanbul"},{"key":"10.1016\/j.ghir.2024.101606_bb0030","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s13760-018-01063-6","article-title":"Relationship of leptin, growth hormone, and insulin-like growth factor levels with body mass index and disease severity in patients with fibromyalgia syndrome","volume":"120","author":"Koca","year":"2020","journal-title":"Acta Neurol. Belg."},{"key":"10.1016\/j.ghir.2024.101606_bb0035","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/nrendo.2018.22","article-title":"Growth hormone\u2014past, present and future","volume":"14","author":"Ranke","year":"2018","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.ghir.2024.101606_bb0040","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.molmet.2015.03.005","article-title":"Ghrelin","volume":"4","author":"M\u00fcller","year":"2015","journal-title":"Mol. Metabol."},{"key":"10.1016\/j.ghir.2024.101606_bb0045","doi-asserted-by":"crossref","DOI":"10.1590\/1806-9282.20230240","article-title":"The relationship between serum leptin, insulin-like growth factor-1, and insulin-like growth factor binding protein-3 levels and clinical parameters in primary fibromyalgia patients","volume":"69","author":"Atamer","year":"2023","journal-title":"Rev. Assoc. Med. Bras."},{"key":"10.1016\/j.ghir.2024.101606_bb0050","first-page":"712","article-title":"Dysfunctional eating behavior in fibromyalgia and its association with serum biomarkers of brain plasticity (BDNF and S100B): an exploratory study","volume":"65","author":"Elkfury","year":"2021","journal-title":"Archiv. Endocrinol. Metabol."},{"key":"10.1016\/j.ghir.2024.101606_bb0055","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1590\/2359-3997000000248","article-title":"Serum levels of leptin and adiponectin and clinical parameters in women with fibromyalgia and overweight\/obesity","volume":"61","author":"Paiva","year":"2017","journal-title":"Archiv. Endocrinol. Metabol."},{"key":"10.1016\/j.ghir.2024.101606_bb0060","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.1007\/s00296-014-2988-0","article-title":"Hyperleptinemia independent of body adiposity in women with fibromyalgia","volume":"34","author":"Homann","year":"2014","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.ghir.2024.101606_bb0065","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/1756-185X.12155","article-title":"Serum leptin in E gyptian patients with fibromyalgia syndrome: relation to disease severity","volume":"16","author":"Olama","year":"2013","journal-title":"Int. J. Rheum. Dis."},{"key":"10.1016\/j.ghir.2024.101606_bb0070","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1155\/2012\/350654","article-title":"Evaluation of leptin levels among fibromyalgia patients before and after three months of treatment, in comparison with healthy controls","volume":"17","author":"Ablin","year":"2012","journal-title":"Pain Res. Manag."},{"key":"10.1016\/j.ghir.2024.101606_bb0075","first-page":"809","article-title":"Growth hormone and insulin-like growth factor-1 concentrations in women with fibromyalgia","volume":"30","author":"McCall-Hosenfeld","year":"2003","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.ghir.2024.101606_bb0080","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ghir.2006.12.006","article-title":"Is further evaluation for growth hormone (GH) deficiency necessary in fibromyalgia patients with low serum insulin-like growth factor (IGF)-I levels?","volume":"17","author":"Yuen","year":"2007","journal-title":"Growth Hormon. IGF Res."},{"key":"10.1016\/j.ghir.2024.101606_bb0085","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.jbspin.2007.01.024","article-title":"Serum ghrelin levels but not GH, IGF-1 and IGFBP-3 levels are altered in patients with fibromyalgia syndrome","volume":"74","author":"Tander","year":"2007","journal-title":"Joint Bone Spine"},{"key":"10.1016\/j.ghir.2024.101606_bb0090","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/s00296-004-0459-8","article-title":"Serum growth hormone and insulin but not insulin-like growth factor-1 levels are elevated in patients with fibromyalgia syndrome","volume":"25","author":"Denko","year":"2005","journal-title":"Rheumatol. Int."},{"key":"10.1016\/j.ghir.2024.101606_bb0095","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1749-6632.2002.tb04251.x","article-title":"Blunted ACTH and cortisol responses to systemic injection of corticotropin-releasing hormone (CRH) in fibromyalgia: role of somatostatin and CRH-binding protein","volume":"966","author":"Riedel","year":"2002","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.ghir.2024.101606_bb0100","first-page":"1672","article-title":"Decreased nocturnal levels of prolactin and growth hormone in women with fibromyalgia","volume":"86","author":"Landis","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2024.101606_bb0105","first-page":"3378","article-title":"The growth hormone (GH)-releasing hormone-GH-insulin-like growth factor-1 axis in patients with fibromyalgia syndrome","volume":"84","author":"Leal-Cerro","year":"1999","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2024.101606_bb0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med."},{"key":"10.1016\/j.ghir.2024.101606_bb0115","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2288-5-13","article-title":"Estimating the mean and variance from the median, range, and the size of a sample","volume":"5","author":"Hozo","year":"2005","journal-title":"BMC Med. Res. Methodol."},{"key":"10.1016\/j.ghir.2024.101606_bb0120","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jad.2015.11.052","article-title":"Depression and telomere length: a meta-analysis","volume":"191","author":"Ridout","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ghir.2024.101606_bb0125","author":"Wells"},{"key":"10.1016\/j.ghir.2024.101606_bb0130","first-page":"6","article-title":"Estimating the size of treatment effects: moving beyond p values","volume":"1550-5952","author":"McGough","year":"2009","journal-title":"Psychiatry"},{"key":"10.1016\/j.ghir.2024.101606_bb0135","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1136\/bmj.315.7121.1533","article-title":"Meta-analysis: principles and procedures","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.ghir.2024.101606_bb0140","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control. Clin. Trials"},{"key":"10.1016\/j.ghir.2024.101606_bb0145","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat. Med."},{"key":"10.1016\/j.ghir.2024.101606_bb0150","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.ghir.2024.101606_bb0155","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.1210\/jc.2010-0061","article-title":"High prevalence of growth hormone deficiency in severe fibromyalgia syndromes","volume":"95","author":"Cuatrecasas","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.ghir.2024.101606_bb0160","doi-asserted-by":"crossref","first-page":"116","DOI":"10.4078\/jrd.2023.0005","article-title":"Circulating leptin and its correlation with rheumatoid arthritis activity: a meta-analysis","volume":"30","author":"Lee","year":"2023","journal-title":"J. Rheum. Dis."},{"key":"10.1016\/j.ghir.2024.101606_bb0165","doi-asserted-by":"crossref","first-page":"108","DOI":"10.4078\/jrd.2023.0059","article-title":"Urate-lowering therapy is associated with a reduced risk of arrhythmias: a systematic review and meta-analysis","volume":"31","author":"Waitayangkoon","year":"2024","journal-title":"J. Rheum. Dis."},{"key":"10.1016\/j.ghir.2024.101606_bb0170","doi-asserted-by":"crossref","first-page":"46","DOI":"10.4078\/jrd.2022.29.1.46","article-title":"Mendelian randomization research on the relationship between rheumatoid arthritis and systemic lupus erythematosus and the risk of autistic Spectrum disorder","volume":"29","author":"Lee","year":"2022","journal-title":"J. Rheum. Dis."},{"key":"10.1016\/j.ghir.2024.101606_bb0175","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s100670170003","article-title":"Hormonal responses to exercise stress test in patients with fibromyalgia syndrome","volume":"20","author":"G\u00fcrsel","year":"2001","journal-title":"Clin. Rheumatol."}],"container-title":["Growth Hormone &amp; IGF Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637424000364?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096637424000364?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T19:32:25Z","timestamp":1723059145000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096637424000364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":35,"alternative-id":["S1096637424000364"],"URL":"https:\/\/doi.org\/10.1016\/j.ghir.2024.101606","relation":{},"ISSN":["1096-6374"],"issn-type":[{"value":"1096-6374","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of circulating leptin, growth hormone, and ghrelin with fibromyalgia: A meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Growth Hormone & IGF Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ghir.2024.101606","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101606"}}