{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T10:45:25Z","timestamp":1787222725916,"version":"build-2736575974"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","giejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.gie.2008.04.065","type":"journal-article","created":{"date-parts":[[2008,10,24]],"date-time":"2008-10-24T05:39:15Z","timestamp":1224826755000},"page":"221-229","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Higher hospital volume predicts endoscopy but not the in-hospital mortality rate in patients with acute variceal hemorrhage"],"prefix":"10.1016","volume":"69","author":[{"given":"Ashwin N.","family":"Ananthakrishnan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily L.","family":"McGinley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kia","family":"Saeian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gie.2008.04.065_bib1","first-page":"1","article-title":"Deaths: preliminary data for 2004","volume":"54","author":"Minino","year":"2006","journal-title":"Natl Vital Stat Rep"},{"key":"10.1016\/j.gie.2008.04.065_bib2","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1111\/j.1572-0241.2006.00723.x","article-title":"The burden of gastrointestinal and liver diseases","volume":"101","author":"Shaheen","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2008.04.065_bib3","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1111\/j.1572-0241.2003.t01-1-07705.x","article-title":"An assessment of the management of acute bleeding varices: a multicenter prospective member-based study","volume":"98","author":"Sorbi","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2008.04.065_bib4","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/j.1572-0241.2003.07294.x","article-title":"Improved patient survival after acute variceal bleeding: a multicenter, cohort study","volume":"98","author":"Chalasani","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2008.04.065_bib5","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1111\/j.1572-0241.2007.01481.x","article-title":"Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis","volume":"102","author":"Garcia-Tsao","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2008.04.065_bib6","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.gtc.2005.08.008","article-title":"Bleeding caused by portal hypertension","volume":"34","author":"Zaman","year":"2005","journal-title":"Gastroenterol Clin North Am"},{"key":"10.1016\/j.gie.2008.04.065_bib7","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1056\/NEJMsa035205","article-title":"Surgeon volume and operative mortality in the United States","volume":"349","author":"Birkmeyer","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gie.2008.04.065_bib8","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/bjs.5714","article-title":"A systematic review of the impact of volume of surgery and specialization on patient outcome","volume":"94","author":"Chowdhury","year":"2007","journal-title":"Br J Surg"},{"key":"10.1016\/j.gie.2008.04.065_bib9","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1067\/mva.2003.207","article-title":"Hospital volume-related differences in aorto-bifemoral bypass operative mortality in the United States","volume":"37","author":"Dimick","year":"2003","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.gie.2008.04.065_bib10","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S0022-4804(03)00207-5","article-title":"Hospital volume and surgical outcomes for elderly patients with colorectal cancer in the United States","volume":"114","author":"Dimick","year":"2003","journal-title":"J Surg Res"},{"key":"10.1016\/j.gie.2008.04.065_bib11","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1377\/hlthaff.22.2.167","article-title":"Volume thresholds and hospital characteristics in the United States","volume":"22","author":"Elixhauser","year":"2003","journal-title":"Health Aff (Millwood)"},{"key":"10.1016\/j.gie.2008.04.065_bib12","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1016\/j.jacc.2003.09.070","article-title":"Hospital percutaneous coronary intervention volume and patient mortality, 1998 to 2000: does the evidence support current procedure volume minimums?","volume":"43","author":"Epstein","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.gie.2008.04.065_bib13","doi-asserted-by":"crossref","first-page":"539","DOI":"10.2105\/AJPH.2005.075663","article-title":"Relationship between number of breast cancer operations performed and 5-year survival after treatment for early-stage breast cancer","volume":"97","author":"Gilligan","year":"2007","journal-title":"Am J Public Health"},{"key":"10.1016\/j.gie.2008.04.065_bib14","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1056\/NEJM199412153312406","article-title":"The relation between the volume of coronary angioplasty procedures at hospitals treating Medicare beneficiaries and short-term mortality","volume":"331","author":"Jollis","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gie.2008.04.065_bib15","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1245\/s10434-006-9005-0","article-title":"Hospital volume and inpatient mortality after cancer-related gastrointestinal resections: the experience of an Asian country","volume":"13","author":"Lin","year":"2006","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.gie.2008.04.065_bib16","doi-asserted-by":"crossref","first-page":"649","DOI":"10.7326\/0003-4819-139-8-200310210-00008","article-title":"Association of hospital procedure volume and outcomes in patients with colon cancer at high risk for recurrence","volume":"139","author":"Meyerhardt","year":"2003","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.gie.2008.04.065_bib17","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1097\/01.sla.0000103066.22732.b8","article-title":"Hospital coronary artery bypass graft surgery volume and patient mortality, 1998-2000","volume":"239","author":"Rathore","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.gie.2008.04.065_bib18","doi-asserted-by":"crossref","first-page":"3028","DOI":"10.1001\/jama.284.23.3028","article-title":"Influence of hospital procedure volume on outcomes following surgery for colon cancer","volume":"284","author":"Schrag","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.gie.2008.04.065_bib19","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1001\/archsurg.142.4.387","article-title":"National outcomes after gastric resection for neoplasm","volume":"142","author":"Smith","year":"2007","journal-title":"Arch Surg"},{"key":"10.1016\/j.gie.2008.04.065_bib20","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.jamcollsurg.2006.07.009","article-title":"Small rural hospitals and high-risk operations: how would regionalization affect surgical volume and hospital revenue?","volume":"203","author":"Chappel","year":"2006","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.gie.2008.04.065_bib21","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1001\/jama.1995.03530160034030","article-title":"Regionalization of cardiac surgery in the United States and Canada: geographic access, choice, and outcomes","volume":"274","author":"Grumbach","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.gie.2008.04.065_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/095148489701000101","article-title":"Regionalization of tertiary care: impact of safe cardiovascular volumes in Iowa","volume":"10","author":"Rohrer","year":"1997","journal-title":"Health Serv Manage Res"},{"key":"10.1016\/j.gie.2008.04.065_bib23","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1097\/01.CCM.0000226415.93237.84","article-title":"Impact of patient volume on the mortality rate of adult intensive care unit patients","volume":"34","author":"Glance","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.gie.2008.04.065_bib24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1056\/NEJMsa053993","article-title":"Hospital volume and the outcomes of mechanical ventilation","volume":"355","author":"Kahn","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gie.2008.04.065_bib25","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1097\/01.CCM.0000233858.85802.5C","article-title":"Hospital volume and mortality for mechanical ventilation of medical and surgical patients: a population-based analysis using administrative data","volume":"34","author":"Needham","year":"2006","journal-title":"Crit Care Med"},{"key":"10.1016\/j.gie.2008.04.065_bib26","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/intqhc\/mzg016","article-title":"Hospital experience and outcomes for esophageal variceal bleeding","volume":"15","author":"Dy","year":"2003","journal-title":"Int J Qual Health Care"},{"key":"10.1016\/j.gie.2008.04.065_bib27","unstructured":"HCUP nationwide inpatient sample (NIS): Healthcare Cost and Utilization Project (HCUP). Rockville, Md: Agency for Healthcare Research and Quality. Available at: www.hcup-us.ahrq.gov\/nisoverview.jsp. Accessed June 6, 2008."},{"key":"10.1016\/j.gie.2008.04.065_bib28","first-page":"143","article-title":"The healthcare cost and utilization project: an overview","volume":"5","author":"Steiner","year":"2002","journal-title":"Eff Clin Pract"},{"key":"10.1016\/j.gie.2008.04.065_bib29","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1056\/NEJM200107193450306","article-title":"The influence of hospital volume on survival after resection for lung cancer","volume":"345","author":"Bach","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gie.2008.04.065_bib30","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1001\/archsurg.139.2.137","article-title":"Hospital teaching status and outcomes of complex surgical procedures in the United States","volume":"139","author":"Dimick","year":"2004","journal-title":"Arch Surg"},{"key":"10.1016\/j.gie.2008.04.065_bib31","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1002\/hep.21580","article-title":"Racial disparities in the management of hospitalized patients with cirrhosis and complications of portal hypertension: a national study","volume":"45","author":"Nguyen","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.gie.2008.04.065_bib32","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J Chron Dis"},{"key":"10.1016\/j.gie.2008.04.065_bib33","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(92)90133-8","article-title":"Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases","volume":"45","author":"Deyo","year":"1992","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.gie.2008.04.065_bib34","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1681\/ASN.2006010073","article-title":"Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for acute renal failure","volume":"17","author":"Waikar","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.gie.2008.04.065_bib35","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0016-5107(00)70442-1","article-title":"The accuracy of diagnosis and procedural codes for patients with upper GI hemorrhage","volume":"51","author":"Cooper","year":"2000","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2008.04.065_bib36","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/1468-0009.00023","article-title":"Teaching hospitals and quality of care: a review of the literature","volume":"80","author":"Ayanian","year":"2002","journal-title":"Milbank Q"},{"key":"10.1016\/j.gie.2008.04.065_bib37","doi-asserted-by":"crossref","first-page":"7122","DOI":"10.3748\/wjg.v11.i45.7122","article-title":"Outcome of non-variceal acute upper gastrointestinal bleeding in relation to the time of endoscopy and the experience of the endoscopist: a two-year survey","volume":"11","author":"Parente","year":"2005","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.gie.2008.04.065_bib38","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1053\/gast.1996.v111.pm8698192","article-title":"Transjugular intrahepatic portosystemic shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy","volume":"111","author":"Sanyal","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2008.04.065_bib39","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1001\/jama.1997.03550060061037","article-title":"Severity-adjusted mortality and length of stay in teaching and nonteaching hospitals: results of a regional study","volume":"278","author":"Rosenthal","year":"1997","journal-title":"JAMA"}],"container-title":["Gastrointestinal Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510708018208?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510708018208?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:07:16Z","timestamp":1758038836000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016510708018208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0016510708018208"],"URL":"https:\/\/doi.org\/10.1016\/j.gie.2008.04.065","relation":{},"ISSN":["0016-5107"],"issn-type":[{"value":"0016-5107","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Higher hospital volume predicts endoscopy but not the in-hospital mortality rate in patients with acute variceal hemorrhage","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2008.04.065","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}