{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T10:34:17Z","timestamp":1792319657958,"version":"4.4.0"},"reference-count":13,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","giejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.gie.2009.08.023","type":"journal-article","created":{"date-parts":[[2009,11,18]],"date-time":"2009-11-18T08:37:33Z","timestamp":1258533453000},"page":"249-255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Periductal hypoechoic sign: an endosonographic finding associated with pancreatic malignancy"],"prefix":"10.1016","volume":"71","author":[{"given":"Suck-Ho","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuri","family":"Ozden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishi","family":"Pawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young","family":"Hwangbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas K.","family":"Pleskow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram","family":"Chuttani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandeep S.","family":"Sawhney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gie.2009.08.023_bib1","unstructured":"The SEER Cancer Statistics Review, National Cancer Institute, 1975-2005. Available at: http:\/\/seer.cancer.gov\/csr\/1975_2005\/. Accessed January 5, 2009."},{"key":"10.1016\/j.gie.2009.08.023_bib2","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1148\/radiol.2243011284","article-title":"Isoattenuating pancreatic adenocarcinoma at multi-detector row CT: secondary signs","volume":"224","author":"Prokesch","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.gie.2009.08.023_bib3","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1097\/MPA.0b013e318175e3a0","article-title":"Strategy for differentiating autoimmune pancreatitis from pancreatic cancer","volume":"37","author":"Kamisawa","year":"2008","journal-title":"Pancreas"},{"key":"10.1016\/j.gie.2009.08.023_bib4","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S0140-6736(00)02479-X","article-title":"Pancreatic cancer detection with magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography: a prospective controlled study","volume":"356","author":"Adamek","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.gie.2009.08.023_bib5","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/jjco\/hyf093","article-title":"Main pancreatic duct dilatation: a sign of high risk for pancreatic cancer","volume":"32","author":"Tanaka","year":"2002","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.gie.2009.08.023_bib6","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/S0016-5085(97)70164-1","article-title":"Endosonography-guided fine-needle aspiration biopsy: diagnostic accuracy and complication assessment","volume":"112","author":"Wiersema","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2009.08.023_bib7","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.gie.2005.06.051","article-title":"Yield of EUS-guided FNA of pancreatic masses in the presence or the absence of chronic pancreatitis","volume":"62","author":"Varadarajulu","year":"2005","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2009.08.023_bib8","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1111\/j.1572-0241.2002.07020.x","article-title":"Comparison of endoscopic ultrasound-guided fine needle aspiration for focal pancreatic lesions in patients with normal parenchyma and chronic pancreatitis","volume":"97","author":"Fritscher-Ravens","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2009.08.023_bib9","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.gie.2008.04.031","article-title":"Neural network analysis of dynamic sequences of EUS elastography used for the differential diagnosis of chronic pancreatitis and pancreatic cancer","volume":"68","author":"S\u0103ftoiu","year":"2008","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2009.08.023_bib10","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1067\/S0016-5107(03)01962-X","article-title":"Severe localized stenosis and marked dilatation of the main pancreatic duct are indicators of pancreatic cancer instead of chronic pancreatitis on endoscopic retrograde balloon pancreatography","volume":"58","author":"Inoue","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2009.08.023_bib11","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1055\/s-2008-1077726","article-title":"Indications and limitations of endoscopic ultrasound elastography for evaluation of focal pancreatic lesions","volume":"40","author":"Hirche","year":"2008","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2009.08.023_bib12","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1067\/mge.2000.105775","article-title":"The double duct sign in patients with malignant and benign pancreatic lesions","volume":"52","author":"Menges","year":"2000","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2009.08.023_bib13","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1111\/j.1572-0241.2004.04177.x","article-title":"Endoscopic ultrasound-guided fine needle aspiration and multidetector spiral CT in the diagnosis of pancreatic cancer","volume":"99","author":"Agarwal","year":"2004","journal-title":"Am J Gastroenterol"}],"container-title":["Gastrointestinal Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510709024237?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510709024237?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:12:03Z","timestamp":1758039123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016510709024237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S0016510709024237"],"URL":"https:\/\/doi.org\/10.1016\/j.gie.2009.08.023","relation":{},"ISSN":["0016-5107"],"issn-type":[{"value":"0016-5107","type":"print"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Periductal hypoechoic sign: an endosonographic finding associated with pancreatic malignancy","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2009.08.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2010.01.004","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}