{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:35:29Z","timestamp":1791290129883,"version":"4.3.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","giejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.gie.2010.02.040","type":"journal-article","created":{"date-parts":[[2010,6,12]],"date-time":"2010-06-12T04:34:27Z","timestamp":1276317267000},"page":"255-264.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":279,"title":["Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with video)"],"prefix":"10.1016","volume":"72","author":[{"given":"Hiroaki","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiaki","family":"Arimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hosokawa","family":"Masao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Okahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tokuma","family":"Tanuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichi","family":"Kodaira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetoshi","family":"Kagaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaku","family":"Hokari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Tsukagoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhisa","family":"Shinomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gie.2010.02.040_bib1","first-page":"476","article-title":"Recent advances in endoscopic mucosal resection for early gastric cancer","volume":"25","author":"Hosokawa","year":"1998","journal-title":"Gan To Kogaku Ryoho"},{"key":"10.1016\/j.gie.2010.02.040_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1136\/gut.48.2.225","article-title":"Endoscopic mucosal resection for treatment of early gastric cancer","volume":"48","author":"Ono","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.gie.2010.02.040_bib3","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.gie.2007.08.018","article-title":"Local recurrence of large squamous-cell carcinoma of the esophagus after endoscopic resection","volume":"67","author":"Ishihara","year":"2008","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib4","doi-asserted-by":"crossref","unstructured":"Fujishiro M, Yahagi N, Kakushima N, et al. Endoscopic submucosal dissection of esophageal squamous cell neoplasms. Clin Gastroenterol Hepatol 200;4:688-94.","DOI":"10.1016\/j.cgh.2006.03.024"},{"key":"10.1016\/j.gie.2010.02.040_bib5","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1016\/S1542-3565(05)00291-0","article-title":"Endoscopic submucosal dissection of early esophageal cancer","volume":"3","author":"Oyama","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gie.2010.02.040_bib6","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.gie.2008.03.1114","article-title":"Comparison of EMR and endoscopic submucosal dissection for en bloc resection of early esophageal cancers in Japan","volume":"68","author":"Ishihara","year":"2008","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib7","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1055\/s-2005-921039","article-title":"Efficacy and safety of endoscopic submucosal dissection for tumors of the esophagogastric junction","volume":"38","author":"Kakushima","year":"2006","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib8","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1002\/(SICI)1097-0142(20000315)88:6<1285::AID-CNCR3>3.0.CO;2-R","article-title":"Histopathologic findings predicting lymph node metastasis and prognosis of patients with superficial esophageal carcinoma: analysis of 240 surgically resected tumors","volume":"88","author":"Tajima","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.gie.2010.02.040_bib9","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/modpathol.3800557","article-title":"Histopathological criteria for additional treatment after endoscopic mucosal resection for esophageal cancer: analysis of 464 surgically resected cases","volume":"19","author":"Eguchi","year":"2006","journal-title":"Mod Pathol"},{"key":"10.1016\/j.gie.2010.02.040_bib10","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1349-7006.2002.tb02173.x","article-title":"Evaluation of an indicator for lymph node metastasis of esophageal squamous cell carcinoma invading the submucosal layer","volume":"93","author":"Nakajima","year":"2002","journal-title":"Jpn J Cancer Res"},{"key":"10.1016\/j.gie.2010.02.040_bib11","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/cncr.10190","article-title":"Pathologic features of superficial esophageal squamous cell carcinoma with lymph node and distal metastasis","volume":"94","author":"Araki","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.gie.2010.02.040_bib12","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1111\/j.1440-1746.2005.03858.x","article-title":"Tumor cell dissociation score highly correlates with lymph node metastasis in superficial esophageal carcinoma","volume":"20","author":"Chibana","year":"2005","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.gie.2010.02.040_bib13","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1111\/j.1572-0241.2004.30628.x","article-title":"Endoscopic resection of superficial esophageal squamous-cell carcinomas: western experience","volume":"99","author":"Pech","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2010.02.040_bib14","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1055\/s-2006-945182","article-title":"Endoscopic mucosal resection for squamous premalignant and early malignant lesions of the esophagus","volume":"39","author":"Ciocirlan","year":"2007","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib15","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1055\/s-2007-966761","article-title":"Clinical outcome after endoscopic mucosal resection for esophageal squamous cell carcinoma invading the muscularis mucosae: a multicenter retrospective cohort study","volume":"39","author":"Katada","year":"2007","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib16","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0016-5107(04)02756-7","article-title":"Local recurrence of squamous-cell carcinoma of the esophagus after EMR","volume":"61","author":"Katada","year":"2005","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib17","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1055\/s-2006-945040","article-title":"Curative endoscopic therapy in patients with early esophageal squamous-cell carcinoma or high-grade intraepithelial neoplasia","volume":"39","author":"Pech","year":"2007","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib18","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1055\/s-2000-7379","article-title":"Recurrence after endoscopic mucosal resection for superficial esophageal cancer","volume":"32","author":"Nomura","year":"2000","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib19","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0016-5107(02)70436-7","article-title":"Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal squamous cell carcinoma in patients with head and neck cancer","volume":"56","author":"Muto","year":"2002","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib20","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1067\/mge.2001.116877","article-title":"Metachronous squamous cell carcinoma of the esophagus arising after endoscopic mucosal resection","volume":"54","author":"Shimizu","year":"2001","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib21","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1055\/s-2006-945143","article-title":"Risk factors for local recurrence of superficial esophageal cancer after treatment by endoscopic mucosal resection","volume":"39","author":"Esaki","year":"2007","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib22","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1055\/s-2006-944809","article-title":"Endoscopic submucosal dissection for early gastric cancers and large flat adenomas","volume":"38","author":"Onozato","year":"2006","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib23","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.gie.2005.08.049","article-title":"Clinical outcomes of EMR for gastric tumors: historical pilot evaluation between endoscopic submucosal dissection and conventional mucosal resection","volume":"63","author":"Watanabe","year":"2006","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib24","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1136\/gut.2008.165381","article-title":"Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study","volume":"58","author":"Isomoto","year":"2009","journal-title":"Gut"},{"key":"10.1016\/j.gie.2010.02.040_bib25","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1055\/s-0029-1215053","article-title":"Meta-analysis of endoscopic submucosal resection versus endoscopic mucosal resection for tumors of the gastrointestinal tract","volume":"41","author":"Cao","year":"2009","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2010.02.040_bib26","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3164\/jcbn.SR09-01","article-title":"Endoscopic submucosal dissection in the era of proton pump inhibitors","volume":"44","author":"Isomoto","year":"2009","journal-title":"J Clin Biochem Nutr"},{"key":"10.1016\/j.gie.2010.02.040_bib27","article-title":"Japanese Classification of Esophageal Cancer","year":"2008"},{"key":"10.1016\/j.gie.2010.02.040_bib28","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1001\/jama.1997.03540350075038","article-title":"Recommendations guiding physicians in biomedical research involving human subjects","volume":"277","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.gie.2010.02.040_bib29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/den.1996.8.3.175","article-title":"Endoscopic mucosal resection for early esophageal cancer: indication and techniques","volume":"8","author":"Makuuchi","year":"1996","journal-title":"Dig Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib30","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/BF02498820","article-title":"A new simplified technique of endoscopic esophageal mucosal resection using a cap-fitted panendoscope","volume":"6","author":"Inoue","year":"1992","journal-title":"Surg Endosc"},{"key":"10.1016\/j.gie.2010.02.040_bib31","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression Models and Life Tables","volume":"34","author":"Cox","year":"1972","journal-title":"J R Stat So Ser B Stat Soc"},{"key":"10.1016\/j.gie.2010.02.040_bib32","first-page":"1223","article-title":"Analysis of long term follow up patients after endoscopic mucosal resection for early esophageal cancer: with special reference to metachronous multiple cancers","volume":"31","author":"Makuuchi","year":"1996","journal-title":"Stomach Intestine"},{"key":"10.1016\/j.gie.2010.02.040_bib33","first-page":"1217","article-title":"Local recurrence of esophageal squamous cell carcinoma after endoscopic esophageal mucosal resection","volume":"31","author":"Oyama","year":"1996","journal-title":"Stomach Intestine"},{"key":"10.1016\/j.gie.2010.02.040_bib34","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1046\/j.1440-1827.1999.00838.x","article-title":"Esophageal adenocarcinoma that probably originated in the esophageal gland duct: a case report","volume":"49","author":"Endoh","year":"1999","journal-title":"Pathol Int"}],"container-title":["Gastrointestinal Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001651071000252X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001651071000252X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T16:15:11Z","timestamp":1758039311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001651071000252X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S001651071000252X"],"URL":"https:\/\/doi.org\/10.1016\/j.gie.2010.02.040","relation":{},"ISSN":["0016-5107"],"issn-type":[{"value":"0016-5107","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with video)","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2010.02.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}