{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:14:28Z","timestamp":1789679668099,"version":"4.0.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","giejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.gie.2017.07.024","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T14:32:08Z","timestamp":1500561128000},"page":"457-465","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Effect of scheduled second-look endoscopy on peptic ulcer bleeding: a prospective randomized multicenter trial"],"prefix":"10.1016","volume":"87","author":[{"given":"Soo Jung","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyojin","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Chan","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Hwan","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Joo","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Chul","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie-Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Hoon","family":"Youn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hak","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang Jae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun Gyo","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyungkil","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byoung Wook","family":"Bang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gie.2017.07.024_bib1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.7326\/0003-4819-152-2-201001190-00009","article-title":"International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding","volume":"152","author":"Barkun","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.gie.2017.07.024_bib2","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.gie.2014.09.027","article-title":"The in-hospital mortality rate for upper GI hemorrhage has decreased over 2 decades in the United States: a nationwide analysis","volume":"81","author":"Abougergi","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2017.07.024_bib3","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1038\/ajg.2012.168","article-title":"Trends for incidence of hospitalization and death due to GI complications in the United States from 2001 to 2009","volume":"107","author":"Laine","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2017.07.024_bib4","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1111\/j.1572-0241.2008.02070.x","article-title":"Systematic review of the predictors of recurrent hemorrhage after endoscopic hemostatic therapy for bleeding peptic ulcers","volume":"103","author":"Elmunzer","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2017.07.024_bib5","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1001\/jama.1990.03450040090037","article-title":"Endoscopic hemostasis. An effective therapy for bleeding peptic ulcers","volume":"264","author":"Sacks","year":"1990","journal-title":"JAMA"},{"key":"10.1016\/j.gie.2017.07.024_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0016-5085(92)91793-4","article-title":"Endoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: a meta-analysis","volume":"102","author":"Cook","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2017.07.024_bib7","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1038\/ajg.2013.162","article-title":"Improving quality of care in peptic ulcer bleeding: nationwide cohort study of 13,498 consecutive patients in the Danish Clinical Register of Emergency Surgery","volume":"108","author":"Rosenstock","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2017.07.024_bib8","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1055\/s-2007-1001369","article-title":"Second thoughts about second-look endoscopy for ulcer bleeding?","volume":"30","author":"Saeed","year":"1998","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2017.07.024_bib9","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0016-5107(94)70006-0","article-title":"Value of second-look endoscopy after injection therapy for bleeding peptic ulcer: a prospective and randomized trial","volume":"40","author":"Villanueva","year":"1994","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2017.07.024_bib10","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/S0140-6736(97)03233-9","article-title":"Randomised trial of single and repeated fibrin glue compared with injection of polidocanol in treatment of bleeding peptic ulcer","volume":"350","author":"Rutgeerts","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.gie.2017.07.024_bib11","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1055\/s-2007-1001360","article-title":"Effect of programmed endoscopic follow-up examinations on the rebleeding rate of gastric or duodenal peptic ulcers treated by injection therapy: a prospective, randomized controlled trial","volume":"30","author":"Messmann","year":"1998","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2017.07.024_bib12","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1055\/s-2007-1005455","article-title":"Endoscopic retreatment after successful initial hemostasis prevents ulcer rebleeding: a prospective randomized trial","volume":"28","author":"Saeed","year":"1996","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2017.07.024_bib13","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1136\/gut.52.10.1403","article-title":"Effect of scheduled second therapeutic endoscopy on peptic ulcer rebleeding: a prospective randomised trial","volume":"52","author":"Chiu","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.gie.2017.07.024_bib14","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1556\/oh.2009.28725","article-title":"The value of routine second-look endoscopy in the management of acute gastroduodenal ulcer bleeding","volume":"150","author":"Szocs","year":"2009","journal-title":"Orv Hetil"},{"key":"10.1016\/j.gie.2017.07.024_bib15","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0016-5107(04)01568-8","article-title":"ASGE guideline: the role of endoscopy in acute non-variceal upper-GI hemorrhage","volume":"60","author":"Adler","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2017.07.024_bib16","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1440-1746.2009.06129.x","article-title":"Second-look endoscopy with thermal coagulation or injections for peptic ulcer bleeding: a meta-analysis","volume":"25","author":"Tsoi","year":"2010","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.gie.2017.07.024_bib17","doi-asserted-by":"crossref","first-page":"iv1","DOI":"10.1136\/gut.51.suppl_4.iv1","article-title":"Non-variceal upper gastrointestinal haemorrhage: guidelines","volume":"51","year":"2002","journal-title":"Gut"},{"key":"10.1016\/j.gie.2017.07.024_bib18","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1067\/mge.2003.48","article-title":"Outcome of endoscopic treatment for peptic ulcer bleeding: Is a second look necessary? A meta-analysis","volume":"57","author":"Marmo","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2017.07.024_bib19","doi-asserted-by":"crossref","first-page":"a1","DOI":"10.1055\/s-0034-1393172","article-title":"Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline","volume":"47","author":"Gralnek","year":"2015","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2017.07.024_bib20","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.gie.2012.04.441","article-title":"Is routine second-look endoscopy effective after endoscopic hemostasis in acute peptic ulcer bleeding? A meta-analysis","volume":"76","author":"El Ouali","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2017.07.024_bib21","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1136\/gut.2010.230292","article-title":"Asia-Pacific Working Group consensus on non-variceal upper gastrointestinal bleeding","volume":"60","author":"Sung","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.gie.2017.07.024_bib22","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.gie.2012.02.033","article-title":"The role of endoscopy in the management of acute non-variceal upper GI bleeding","volume":"75","author":"Hwang","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2017.07.024_bib23","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1055\/s-2007-1001336","article-title":"The evolution of stigmata of hemorrhage in bleeding peptic ulcers: a sequential endoscopic study","volume":"30","author":"Lau","year":"1998","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2017.07.024_bib24","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/ajg.2009.702","article-title":"Methodology for randomized trials of patients with nonvariceal upper gastrointestinal bleeding: recommendations from an international consensus conference","volume":"10","author":"Laine","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2017.07.024_bib25","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1111\/j.1572-0241.2004.30272.x","article-title":"The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting","volume":"99","author":"Barkun","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2017.07.024_bib26","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1007\/s10620-009-1093-9","article-title":"Predictors of rebleeding and mortality in patients with high-risk bleeding peptic ulcers","volume":"55","author":"Cheng","year":"2010","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.gie.2017.07.024_bib27","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s10620-015-3919-y","article-title":"Risk factors for rebleeding in peptic ulcer bleeding: a\u00a0second look at second-look endoscopy","volume":"61","author":"Laursen","year":"2016","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.gie.2017.07.024_bib28","doi-asserted-by":"crossref","first-page":"e71","DOI":"10.1097\/MCG.0b013e3182410351","article-title":"Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis","volume":"46","author":"Imperiale","year":"2012","journal-title":"J\u00a0Clin Gastroenterol"},{"key":"10.1016\/j.gie.2017.07.024_bib29","first-page":"26","article-title":"Clinical characteristics of acute upper gastrointestinal bleeding in a tertiary referral center","volume":"50","author":"Paik","year":"2007","journal-title":"Korean J Gastroenterol"},{"key":"10.1016\/j.gie.2017.07.024_bib30","doi-asserted-by":"crossref","first-page":"E255","DOI":"10.1055\/s-0041-111499","article-title":"Risk factors determining the need for second-look endoscopy for peptic ulcer bleeding after endoscopic hemostasis and proton pump inhibitor infusion","volume":"4","author":"Cheng","year":"2016","journal-title":"Endosc Int Open"},{"key":"10.1016\/j.gie.2017.07.024_bib31","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1111\/j.1572-0241.2003.07517.x","article-title":"Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993\/1994 and 2000","volume":"98","author":"van Leerdam","year":"2003","journal-title":"Am J Gastroenterol"}],"container-title":["Gastrointestinal Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001651071732117X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001651071732117X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T17:09:54Z","timestamp":1758042594000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001651071732117X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["S001651071732117X"],"URL":"https:\/\/doi.org\/10.1016\/j.gie.2017.07.024","relation":{},"ISSN":["0016-5107"],"issn-type":[{"value":"0016-5107","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of scheduled second-look endoscopy on peptic ulcer bleeding: a prospective randomized multicenter trial","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2017.07.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 by the American Society for Gastrointestinal Endoscopy","name":"copyright","label":"Copyright"}]}}