{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:15:14Z","timestamp":1791303314436,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100010909","name":"Braintree Laboratories","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010909","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017519","name":"Aries Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017519","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019638","name":"EndoAid","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019638","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009734","name":"Olympus","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009734","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","giejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.gie.2019.12.052","type":"journal-article","created":{"date-parts":[[2020,1,15]],"date-time":"2020-01-15T10:39:43Z","timestamp":1579084783000},"page":"1027-1036.e9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":58,"title":["High-definition colonoscopy for improving adenoma detection:\u00a0a systematic review and meta-analysis of randomized\u00a0controlled studies"],"prefix":"10.1016","volume":"91","author":[{"given":"Georgios","family":"Tziatzios","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paraskevas","family":"Gkolfakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lazaros Dimitrios","family":"Lazaridis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Facciorusso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Antonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Repici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prateek","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas K.","family":"Rex","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Triantafyllou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gie.2019.12.052_bib1","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1055\/s-0043-103411","article-title":"Performance measures for lower gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) quality improvement initiative","volume":"49","author":"Kaminski","year":"2017","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1053\/j.gastro.2017.04.006","article-title":"Increased rate of adenoma detection associates with reduced risk of colorectal cancer and death","volume":"153","author":"Kaminski","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2019.12.052_bib3","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1055\/s-0034-1365348","article-title":"Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) guideline","volume":"46","author":"Kaminski","year":"2014","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib4","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.cgh.2009.11.009","article-title":"High-definition colonoscopy detects colorectal polyps at a higher rate than standard white-light colonoscopy","volume":"8","author":"Buchner","year":"2010","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gie.2019.12.052_bib5","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1055\/s-0032-1310004","article-title":"High-definition vs standard-definition colonoscopy in the characterization of small colonic polyps: results from a randomized trial","volume":"44","author":"Longcroft-Wheaton","year":"2012","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib6","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1055\/s-0030-1256207","article-title":"High definition colonoscopy vs standard video endoscopy for the detection of colonic polyps: a meta-analysis","volume":"43","author":"Subramanian","year":"2011","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"10.1016\/j.gie.2019.12.052_bib8","unstructured":"Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration; 2011. Available at: https:\/\/handbook-5-1.cochrane.org\/. Accessed December 9, 2019."},{"key":"10.1016\/j.gie.2019.12.052_bib9","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.gie.2019.12.052_bib10","unstructured":"Sch\u00fcnemann H, Bro\u017cek J, Guyatt G, et\u00a0al, editors. GRADE handbook for grading quality of evidence and strength of recommendations (Updated October 2013). The GRADE Working Group; 2013. Available at: https:\/\/gdt.gradepro.org\/app\/handbook\/handbook.html. Accessed January 28,\u00a02019."},{"key":"10.1016\/j.gie.2019.12.052_bib11","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1053\/j.gastro.2008.06.090","article-title":"Impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia: a randomized controlled trial","volume":"135","author":"Pellise","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2019.12.052_bib12","doi-asserted-by":"crossref","first-page":"e260","DOI":"10.1111\/j.1463-1318.2009.02145.x","article-title":"Comparison of standard vs high-definition, wide-angle colonoscopy for polyp detection: a randomized controlled trial","volume":"12","author":"Tribonias","year":"2010","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.gie.2019.12.052_bib13","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.gie.2011.04.050","article-title":"Randomized, controlled trial of standard-definition white-light, high-definition white-light, and narrow-band imaging colonoscopy for the detection of colon polyps and prediction of polyp histology","volume":"74","author":"Rastogi","year":"2011","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2019.12.052_bib14","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.gie.2018.01.025","article-title":"Impact of 2 generational improvements in colonoscopes on adenoma miss rates: results of a prospective randomized multicenter tandem study","volume":"88","author":"Pioche","year":"2018","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2019.12.052_bib15","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1055\/a-0607-2636","article-title":"Effects of two instrument-generation changes on adenoma detection rate during screening colonoscopy: results from a prospective randomized comparative study","volume":"50","author":"Zimmermann-Fraedrich","year":"2018","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib16","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1055\/a-0755-7471","article-title":"Impact of endoscopy system, high definition, and virtual chromoendoscopy in daily routine colonoscopy: a randomized trial","volume":"51","author":"Roelandt","year":"2019","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib17","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/gut.47.2.251","article-title":"The Vienna classification of gastrointestinal epithelial neoplasia","volume":"47","author":"Schlemper","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.gie.2019.12.052_bib18","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1136\/gut.51.1.130","article-title":"Gastrointestinal epithelial neoplasia: Vienna revisited","volume":"51","author":"Dixon","year":"2002","journal-title":"Gut"},{"key":"10.1016\/j.gie.2019.12.052_bib19","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/his.13975","article-title":"The 2019 WHO classification of tumours of the digestive system","volume":"76","author":"Nagtegaal","year":"2020","journal-title":"Histopathology"},{"key":"10.1016\/j.gie.2019.12.052_bib20","first-page":"44","article-title":"New-generation high-definition colonoscopes increase adenoma detection when screening a moderate-risk population for colorectal cancer","volume":"16","author":"Bond","year":"2017","journal-title":"Clin Colorectal Cancer"},{"key":"10.1016\/j.gie.2019.12.052_bib21","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s00464-016-4986-7","article-title":"High-definition colonoscopy increases adenoma detection rate","volume":"31","author":"Jrebi","year":"2017","journal-title":"Surg Endosc"},{"key":"10.1016\/j.gie.2019.12.052_bib22","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/s00464-014-3688-2","article-title":"Endoscopists with low adenoma detection rates benefit from high-definition endoscopy","volume":"29","author":"Waldmann","year":"2015","journal-title":"Surg Endosc"},{"key":"10.1016\/j.gie.2019.12.052_bib23","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1111\/den.13282","article-title":"Intensive post-polypectomy surveillance: too much for too little?","volume":"31","author":"Hassan","year":"2019","journal-title":"Dig Endosc"},{"key":"10.1016\/j.gie.2019.12.052_bib24","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1055\/s-0043-113445","article-title":"Calculating the adenoma detection rate in screening colonoscopies only: Is it necessary? Can it be gamed?","volume":"49","author":"Rex","year":"2017","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib25","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1097\/MEG.0000000000001245","article-title":"Meta-analysis indicates that add-on devices and new endoscopes reduce colonoscopy adenoma miss rate","volume":"30","author":"Gkolfakis","year":"2018","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.gie.2019.12.052_bib26","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.gie.2018.10.019","article-title":"Diagnostic yield and miss rate of EndoRings in an organized colorectal cancer screening program: the SMART (Study Methodology for ADR-Related Technology) trial","volume":"89","author":"Hassan","year":"2019","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2019.12.052_bib27","doi-asserted-by":"crossref","first-page":"4243","DOI":"10.3748\/wjg.v24.i37.4243","article-title":"Colonoscopy attachments for the detection of precancerous lesions during colonoscopy: a review of the literature","volume":"24","author":"Gkolfakis","year":"2018","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.gie.2019.12.052_bib28","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1055\/s-0043-102569","article-title":"Colorectal polypectomy and endoscopic mucosal resection (EMR): European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline","volume":"49","author":"Ferlitsch","year":"2017","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib29","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1055\/s-0034-1392882","article-title":"Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline","volume":"47","author":"Pimentel-Nunes","year":"2015","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2019.12.052_bib30","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.1111\/j.1572-0241.2006.00776.x","article-title":"Safety and colon-cleansing efficacy of a new residue-free formulation of sodium phosphate tablets","volume":"101","author":"Rex","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2019.12.052_bib31","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.gie.2008.05.057","article-title":"The Boston Bowel Preparation Scale: a valid and reliable instrument for colonoscopy-oriented research","volume":"69","author":"Lai","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2019.12.052_bib32","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1038\/ajg.2010.273","article-title":"Live image processing does not increase adenoma detection rate during colonoscopy: a randomized comparison between FICE and conventional imaging (Berlin Colonoscopy Project 5, BECOP-5)","volume":"105","author":"Aminalai","year":"2010","journal-title":"Am J Gastroenterol"}],"container-title":["Gastrointestinal Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510720300389?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510720300389?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:58:36Z","timestamp":1762163916000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016510720300389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S0016510720300389"],"URL":"https:\/\/doi.org\/10.1016\/j.gie.2019.12.052","relation":{},"ISSN":["0016-5107"],"issn-type":[{"value":"0016-5107","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High-definition colonoscopy for improving adenoma detection:\u00a0a systematic review and meta-analysis of randomized\u00a0controlled studies","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2019.12.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 by the American Society for Gastrointestinal Endoscopy","name":"copyright","label":"Copyright"}]}}