{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:31:52Z","timestamp":1792621912617,"version":"4.5.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","giejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.gie.2022.08.040","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T11:33:24Z","timestamp":1662464004000},"page":"2-10.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Outcomes of upper endoscopy screening in Lynch syndrome: a meta-analysis"],"prefix":"10.1016","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4088-0095","authenticated-orcid":false,"given":"Shyam","family":"Vedantam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryson W.","family":"Katona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel A.","family":"Sussman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shria","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gie.2022.08.040_bib1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/nrc3878","article-title":"Milestones of Lynch syndrome: 1895-2015","volume":"15","author":"Lynch","year":"2015","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.gie.2022.08.040_bib2","doi-asserted-by":"crossref","DOI":"10.3748\/wjg.v20.i44.16433","article-title":"Causes and consequences of microsatellite instability in gastric carcinogenesis","volume":"20","author":"Velho","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.gie.2022.08.040_bib3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1055\/s-0032-1313781","article-title":"Extracolonic manifestations of Lynch syndrome","volume":"25","author":"Bansidhar","year":"2012","journal-title":"Clin Colon Rectal Surg"},{"key":"10.1016\/j.gie.2022.08.040_bib4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1053\/j.gastro.2003.10.043","article-title":"The role of mismatch repair gene defects in the development of adenomas in patients with HNPCC","volume":"126","author":"De Jong","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2022.08.040_bib5","article-title":"NCCN guidelines for genetic\/familial high-risk assessment","year":"2021","journal-title":"NCCN Clin Pract Guidel Oncol"},{"key":"10.1016\/j.gie.2022.08.040_bib6","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1002\/jso.25645","article-title":"Screening and surgical prophylaxis for hereditary cancer syndromes with high risk of endometrial and ovarian cancer","volume":"120","author":"Bercow","year":"2019","journal-title":"J\u00a0Surg Oncol"},{"key":"10.1016\/j.gie.2022.08.040_bib7","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1053\/j.gastro.2014.04.001","article-title":"Guidelines on genetic evaluation and management of Lynch syndrome: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer","volume":"147","author":"Giardiello","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2022.08.040_bib8","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/ajg.2014.435","article-title":"ACG clinical guideline: genetic testing and management of hereditary gastrointestinal cancer syndromes","volume":"110","author":"Syngal","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2022.08.040_bib9","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1136\/gutjnl-2012-304356","article-title":"Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts","volume":"62","author":"Vasen","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.gie.2022.08.040_bib10","doi-asserted-by":"crossref","first-page":"vi73","DOI":"10.1093\/annonc\/mdt209","article-title":"Familial risk-colorectal cancer: ESMO clinical practice guidelines","volume":"24","author":"Balma\u00f1a","year":"2013","journal-title":"Ann Oncol"},{"key":"10.1016\/j.gie.2022.08.040_bib11","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1200\/JCO.2014.58.1322","article-title":"Hereditary colorectal cancer syndromes: American Society of Clinical Oncology clinical practice guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology clinical practice guidelines","volume":"33","author":"Stoffel","year":"2015","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.gie.2022.08.040_bib12","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ejca.2018.09.004","volume":"104","author":"Vangala","year":"2018","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.gie.2022.08.040_bib13","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1136\/gutjnl-2019-319915","article-title":"Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)\/Association of Coloproctology of Great Britain and Ireland (ACPGBI)\/United Kingdom Cancer Genetics Group (UKCGG)","volume":"69","author":"Monahan","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.gie.2022.08.040_bib14","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1111\/j.1572-0241.2002.05767.x","article-title":"Upper endoscopy as a screening and surveillance tool in esophageal adenocarcinoma: a review of the evidence","volume":"97","author":"Shaheen","year":"2002","journal-title":"Am J Gastroenterol"},{"issue":"Suppl 1","key":"10.1016\/j.gie.2022.08.040_bib15","doi-asserted-by":"crossref","first-page":"i27","DOI":"10.1136\/gut.2004.041566","article-title":"Are screening and surveillance for Barrett\u2019s oesophagus really worthwhile?","volume":"54","author":"Sharma","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.gie.2022.08.040_bib16","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.giec.2021.03.004","article-title":"Endoscopic screening and surveillance for gastric cancer","volume":"31","author":"Kim","year":"2021","journal-title":"Gastrointest Endosc Clin North Am"},{"key":"10.1016\/j.gie.2022.08.040_bib17","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.3390\/cancers14041000","article-title":"Upper gastrointestinal cancer surveillance in Lynch syndrome","volume":"14","author":"Kumar","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.gie.2022.08.040_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PloS Med"},{"key":"10.1016\/j.gie.2022.08.040_bib19","author":"Wells"},{"key":"10.1016\/j.gie.2022.08.040_bib20","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00384-021-04053-y","article-title":"Effectiveness of a surveillance program of upper endoscopy for upper gastrointestinal cancers in Lynch syndrome patients","volume":"37","author":"Ceravolo","year":"2022","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.gie.2022.08.040_bib21","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.3390\/cancers13071657","article-title":"Upper gastrointestinal lesions during endoscopy surveillance in patients with Lynch syndrome: a multicentre cohort study","volume":"13","author":"Chautard","year":"2021","journal-title":"Cancers"},{"key":"10.1016\/j.gie.2022.08.040_bib22","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.gie.2021.07.004","article-title":"Clinically actionable findings on surveillance EGD in asymptomatic patients with Lynch syndrome","volume":"95","author":"Farha","year":"2022","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2022.08.040_bib23","doi-asserted-by":"crossref","first-page":"434","DOI":"10.5152\/tjg.2017.17176","article-title":"Low yield of gastroscopy in patients with Lynch syndrome","volume":"28","author":"Galiatsatos","year":"2017","journal-title":"Turk J Gastroenterol"},{"key":"10.1016\/j.gie.2022.08.040_bib24","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.dld.2018.10.005","article-title":"Duodenal tumor risk in Lynch syndrome","volume":"51","author":"Hammoudi","year":"2019","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.gie.2022.08.040_bib25","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1158\/1940-6207.CAPR-20-0269","article-title":"Upper endoscopic surveillance in Lynch syndrome detects gastric and duodenal adenocarcinomas","volume":"13","author":"Kumar","year":"2020","journal-title":"Cancer Prev Res"},{"key":"10.1016\/j.gie.2022.08.040_bib26","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/ijc.33294","article-title":"Value of upper gastrointestinal endoscopy for gastric cancer surveillance in patients with Lynch syndrome","volume":"148","author":"Ladigan-Badura","year":"2021","journal-title":"Int J Cancer"},{"key":"10.1016\/j.gie.2022.08.040_bib27","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1080\/00365520252903134","article-title":"No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer","volume":"37","author":"Renkonen-Sinisalo","year":"2002","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.gie.2022.08.040_bib28","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1002\/ijc.33753","article-title":"Early detection of duodenal cancer by upper gastrointestinal-endoscopy in Lynch syndrome","volume":"149","author":"Vangala","year":"2021","journal-title":"Int J Cancer"},{"key":"10.1016\/j.gie.2022.08.040_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2288-8-79","article-title":"Undue reliance on I2 in assessing heterogeneity may mislead","volume":"8","author":"R\u00fccker","year":"2008","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.gie.2022.08.040_bib30","doi-asserted-by":"crossref","first-page":"3976","DOI":"10.1002\/cncr.28326","article-title":"The National Lung Screening Trial: results stratified by demographics, smoking history, and lung cancer histology","volume":"119","author":"Pinsky","year":"2013","journal-title":"Cancer"},{"key":"10.1016\/j.gie.2022.08.040_bib31","first-page":"298","article-title":"Screening for colorectal cancer: a systematic review and meta-analysis","volume":"15","author":"Fitzpatrick-Lewis","year":"2016","journal-title":"Clin Colorectal Cancer"},{"key":"10.1016\/j.gie.2022.08.040_bib32","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1001\/jamaoncol.2017.0619","article-title":"Association of mismatch repair mutation with age at cancer onset in Lynch syndrome: implications for stratified surveillance strategies","volume":"3","author":"Ryan","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.gie.2022.08.040_bib33","doi-asserted-by":"crossref","first-page":"31","DOI":"10.18632\/oncoscience.525","article-title":"Upper gastrointestinal cancers in Lynch syndrome: the time for surveillance is now","volume":"8","author":"Kumar","year":"2021","journal-title":"Oncoscience"},{"key":"10.1016\/j.gie.2022.08.040_bib34","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1136\/gutjnl-2020-320839","article-title":"Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis","volume":"69","author":"Ford","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.gie.2022.08.040_bib35","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1053\/j.gastro.2016.01.028","article-title":"Association between Helicobacter pylori eradication and gastric cancer incidence: a systematic review and meta-analysis","volume":"150","author":"Lee","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2022.08.040_bib36","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1053\/j.gastro.2017.04.022","article-title":"Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis","volume":"153","author":"Hooi","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2022.08.040_bib37","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S0016-5107(95)70043-9","article-title":"Interobserver agreement and predictive value of endoscopic findings for H.\u00a0pylori and gastritis in normal volunteers","volume":"42","author":"Laine","year":"1995","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2022.08.040_bib38","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1016\/S0140-6736(20)30366-4","article-title":"Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial","volume":"395","author":"Burn","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.gie.2022.08.040_bib39","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1053\/j.gastro.2005.08.053","article-title":"Prevalence of Barrett\u2019s esophagus in the general population: an endoscopic study","volume":"129","author":"Ronkainen","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2022.08.040_bib40","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/0016-5085(92)91510-B","article-title":"Barrett\u2019s esophagus: age, prevalence, and extent of columnar epithelium","volume":"103","author":"Cameron","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gie.2022.08.040_bib41","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/j.1442-2050.2010.01054.x","article-title":"The prevalence of Barrett\u2019s esophagus in the US: estimates from a simulation model confirmed by SEER data","volume":"23","author":"Hayeck","year":"2010","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.gie.2022.08.040_bib42","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.cancergencyto.2004.08.003","article-title":"Defective mismatch-repair as a minor tumorigenic pathway in Barrett esophagus-associated adenocarcinoma","volume":"157","author":"Falkenback","year":"2005","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.gie.2022.08.040_bib43","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1111\/1759-7714.13311","article-title":"Trends in the incidence and survival of patients with esophageal cancer: a SEER database analysis","volume":"11","author":"He","year":"2020","journal-title":"Thorac Cancer"},{"key":"10.1016\/j.gie.2022.08.040_bib44","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1136\/gutjnl-2014-308124","article-title":"Global incidence of oesophageal cancer by histological subtype in 2012","volume":"64","author":"Arnold","year":"2015","journal-title":"Gut"}],"container-title":["Gastrointestinal Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510722019496?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510722019496?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T17:25:18Z","timestamp":1758043518000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016510722019496"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S0016510722019496"],"URL":"https:\/\/doi.org\/10.1016\/j.gie.2022.08.040","relation":{},"ISSN":["0016-5107"],"issn-type":[{"value":"0016-5107","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes of upper endoscopy screening in Lynch syndrome: a meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2022.08.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by the American Society for Gastrointestinal Endoscopy","name":"copyright","label":"Copyright"}]}}