{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:26:12Z","timestamp":1791897972886,"version":"4.3.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","giejournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.gie.2025.11.035","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T16:37:48Z","timestamp":1764607068000},"page":"86-94","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Optimal endoscopic treatment for rectal neuroendocrine tumors, confirmed after forceps biopsy: a Korean Association for the Study of Intestinal Diseases multicenter, randomized noninferiority trial"],"prefix":"10.1016","volume":"104","author":[{"given":"Tae-Geun","family":"Gweon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Seong","family":"Myung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunho","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7756-2704","authenticated-orcid":false,"given":"Dong-Hoon","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gie.2025.11.035_bib1","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1001\/jamaoncol.2017.0589","article-title":"Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States","volume":"3","author":"Dasari","year":"2017","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.gie.2025.11.035_bib2","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1038\/ajg.2016.267","article-title":"Long-term clinical outcomes of rectal neuroendocrine tumors according to the pathologic status after initial endoscopic resection: a KASID multicenter study","volume":"111","author":"Moon","year":"2016","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib3","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1002\/cncr.20939","article-title":"Early-stage carcinoids of the gastrointestinal tract: an analysis of 1914 reported cases","volume":"103","author":"Soga","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.gie.2025.11.035_bib4","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S1470-2045(07)70410-2","article-title":"Gastroenteropancreatic neuroendocrine tumours","volume":"9","author":"Modlin","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.gie.2025.11.035_bib5","doi-asserted-by":"crossref","DOI":"10.1111\/jne.13309","article-title":"European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for colorectal neuroendocrine tumours","volume":"35","author":"Rinke","year":"2023","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.gie.2025.11.035_bib6","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1055\/a-1751-5742","article-title":"Endoscopic management of subepithelial lesions including neuroendocrine neoplasms: European Society of Gastrointestinal Endoscopy (ESGE) guideline","volume":"54","author":"Deprez","year":"2022","journal-title":"Endoscopy"},{"key":"10.1016\/j.gie.2025.11.035_bib7","doi-asserted-by":"crossref","first-page":"496","DOI":"10.5946\/ce.2022.115","article-title":"Endoscopic treatment for rectal neuroendocrine tumor: which method is better?","volume":"55","author":"Hong","year":"2022","journal-title":"Clin Endosc"},{"key":"10.1016\/j.gie.2025.11.035_bib8","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1080\/00365521.2016.1200140","article-title":"Endoscopic treatments for rectal neuroendocrine tumors smaller than 16 mm: a meta-analysis","volume":"51","author":"Zhang","year":"2016","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib9","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1080\/00365521.2018.1498120","article-title":"Endoscopic mucosal resection with suction vs. endoscopic submucosal dissection for small rectal neuroendocrine tumors: a meta-analysis","volume":"53","author":"Pan","year":"2018","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib10","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1055\/a-1062-8897","article-title":"Efficacy and safety of modified endoscopic mucosal resection for rectal neuroendocrine tumors: a meta-analysis","volume":"58","author":"Zheng","year":"2020","journal-title":"Z Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib11","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.gie.2015.09.046","article-title":"Cap-assisted EMR for rectal neuroendocrine tumors: comparisons with conventional EMR and endoscopic submucosal dissection (with videos)","volume":"83","author":"Yang","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2025.11.035_bib12","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.gie.2014.08.038","article-title":"Effect of prior biopsy sampling, tattoo placement, and snare sampling on endoscopic resection of large nonpedunculated colorectal lesions","volume":"81","author":"Kim","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2025.11.035_bib13","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1159\/000510145","article-title":"Factors associated with fibrosis during colorectal endoscopic submucosal dissection: does pretreatment biopsy potentially elicit submucosal fibrosis and affect endoscopic submucosal dissection outcomes?","volume":"102","author":"Kuroha","year":"2021","journal-title":"Digestion"},{"key":"10.1016\/j.gie.2025.11.035_bib14","doi-asserted-by":"crossref","first-page":"512","DOI":"10.3346\/jkms.2014.29.4.512","article-title":"The effect of preceding biopsy on complete endoscopic resection in rectal carcinoid tumor","volume":"29","author":"Lee","year":"2014","journal-title":"J Korean Med Sci"},{"key":"10.1016\/j.gie.2025.11.035_bib15","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.gie.2024.10.014","article-title":"Safety of cold snare resection techniques for removal of polyps in the small colon in patients taking clopidogrel and aspirin: a Korean Association for the study of intestinal diseases prospective multicenter study","volume":"101","author":"Gweon","year":"2025","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2025.11.035_bib16","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/nrgastro.2016.96","article-title":"Endoscopic mucosal resection and endoscopic submucosal dissection of large colonic polyps","volume":"13","author":"Saunders","year":"2016","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.gie.2025.11.035_bib17","doi-asserted-by":"crossref","first-page":"2773","DOI":"10.1007\/s10620-018-5140-2","article-title":"Factors predictive of complete excision of large colorectal Neoplasia using hybrid endoscopic submucosal dissection: a KASID multicenter study","volume":"63","author":"Jung","year":"2018","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.gie.2025.11.035_bib18","doi-asserted-by":"crossref","first-page":"778","DOI":"10.5946\/ce.2022.268","article-title":"Significance of rescue hybrid endoscopic submucosal dissection in difficult colorectal cases","volume":"56","author":"Yamaguchi","year":"2023","journal-title":"Clin Endosc"},{"key":"10.1016\/j.gie.2025.11.035_bib19","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.gie.2008.05.057","article-title":"The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research","volume":"69","author":"Lai","year":"2009","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.gie.2025.11.035_bib20","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1097\/DCR.0000000000001499","article-title":"Comparison of bowel cleansing efficacy, safety, bowel movement kinetics, and patient tolerability of same-day and split-dose bowel preparation using 4 L of polyethylene glycol: a prospective randomized study","volume":"62","author":"Seo","year":"2019","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.gie.2025.11.035_bib21","doi-asserted-by":"crossref","first-page":"4841","DOI":"10.1007\/s10620-021-07354-y","article-title":"Comparison of 2 L polyethylene glycol plus ascorbic acid and 4 L polyethylene glycol in elderly patients aged 60-79: a prospective randomized study","volume":"67","author":"Jung","year":"2022","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.gie.2025.11.035_bib22","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4253\/wjge.v9.i2.70","article-title":"Endoscopic submucosal dissection for small submucosal tumors of the rectum compared with endoscopic submucosal resection with a ligation device","volume":"9","author":"Harada","year":"2017","journal-title":"World J Gastrointest Endosc"},{"key":"10.1016\/j.gie.2025.11.035_bib23","first-page":"385","article-title":"Comparison between cap-assisted and ligation-assisted endoscopic mucosal resection for rectal neuroendocrine tumors","volume":"33","author":"Lee","year":"2020","journal-title":"Ann Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib24","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1097\/MCG.0b013e31826faf2b","article-title":"Comparison of endoscopic resection therapies for rectal carcinoid tumor: endoscopic submucosal dissection versus endoscopic mucosal resection using band ligation","volume":"47","author":"Choi","year":"2013","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib25","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1001\/jama.295.10.1147","article-title":"Quality of reporting of noninferiority and equivalence randomized trials","volume":"295","author":"Le Henanff","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.gie.2025.11.035_bib26","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s12876-020-01340-w","article-title":"The outcomes of modified endo-scopic mucosal resection and endoscopic submucosal dissection for the treatment of rectal neuroendocrine tumors and the value of endoscopic morphology classification in endoscopic resection","volume":"20","author":"Wang","year":"2020","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib27","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/jgh.12395","article-title":"Endoscopic resection therapies for rectal neuroendocrine tumors: a systematic review and meta-analysis","volume":"29","author":"Zhou","year":"2014","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.gie.2025.11.035_bib28","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.gassur.2023.12.016","article-title":"Endoscopic treatments for rectal neuro-endocrine tumors: a systematic review and network meta-analysis","volume":"28","author":"Chen","year":"2024","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.gie.2025.11.035_bib29","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.14309\/ajg.0000000000001914","article-title":"Modified cap-assisted endoscopic mucosal resection versus endoscopic submucosal dissection for the treatment of rectal neuroendocrine tumors \u226410 mm: a randomized noninferiority trial","volume":"117","author":"Gao","year":"2022","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gie.2025.11.035_bib30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.gie.2007.05.057","article-title":"Prolongation of the period between biopsy and EMR can influence the nonlifting sign in endoscopically resectable colorectal cancers","volume":"67","author":"Han","year":"2008","journal-title":"Gastrointest Endosc"}],"container-title":["Gastrointestinal Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510725022114?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016510725022114?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:34:38Z","timestamp":1785879278000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016510725022114"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0016510725022114"],"URL":"https:\/\/doi.org\/10.1016\/j.gie.2025.11.035","relation":{},"ISSN":["0016-5107"],"issn-type":[{"value":"0016-5107","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optimal endoscopic treatment for rectal neuroendocrine tumors, confirmed after forceps biopsy: a Korean Association for the Study of Intestinal Diseases multicenter, randomized noninferiority trial","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gie.2025.11.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 by the American Society for Gastrointestinal Endoscopy","name":"copyright","label":"Copyright"}]}}