{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T15:00:43Z","timestamp":1781881243768,"version":"3.54.5"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gastrointestinal Endoscopy Clinics of North America"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1016\/j.giec.2006.03.004","type":"journal-article","created":{"date-parts":[[2007,1,10]],"date-time":"2007-01-10T10:10:36Z","timestamp":1168423836000},"page":"229-250","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":78,"title":["Capsule Endoscopy: A Meta-Analysis for Use with Obscure Gastrointestinal Bleeding and Crohn's Disease"],"prefix":"10.1016","volume":"16","author":[{"given":"Jonathan A.","family":"Leighton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart L.","family":"Triester","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virender K.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.giec.2006.03.004_bib1","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1053\/gast.2002.35988","article-title":"A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease","volume":"123","author":"Costamagna","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.giec.2006.03.004_bib2","series-title":"Capsule enteroscopy in obscure gastrointestinal bleeding: a prospective comparative study [abstract]","author":"Toth","year":"2003"},{"key":"10.1016\/j.giec.2006.03.004_bib3","doi-asserted-by":"crossref","first-page":"AB147","DOI":"10.1016\/S0016-5107(04)00708-4","article-title":"M2A wireless capsule endoscopy versus enteroclysis: a prospective study in 68 patients with suspected small bowel disease [abstract]","volume":"59","author":"Apostolopoulos","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib4","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1055\/s-2003-40244","article-title":"Diagnostic value of endoscopic capsule in patients with obscure digestive bleeding: blinded comparison with video push-enteroscopy","volume":"35","author":"Saurin","year":"2003","journal-title":"Endoscopy"},{"key":"10.1016\/j.giec.2006.03.004_bib5","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0016-5107(03)02862-1","article-title":"A prospective comparison of capsule endoscopy and push enteroscopy in patients with GI bleeding of obscure origin","volume":"59","author":"Adler","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib6","first-page":"199","article-title":"A prospective comparative study of push and wireless-capsule enteroscopy in patients with obscure digestive bleeding","volume":"66","author":"Van Gossum","year":"2003","journal-title":"Acta Gastroenterol Belg"},{"key":"10.1016\/j.giec.2006.03.004_bib7","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1136\/gut.52.8.1122","article-title":"Wireless capsule endoscopy: a comparison with push enteroscopy in patients with gastroscopy and colonoscopy negative gastrointestinal bleeding","volume":"52","author":"Mylonaki","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.giec.2006.03.004_bib8","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1055\/s-2003-39330","article-title":"Capsule endoscopy versus push enteroscopy in patients with occult gastrointestinal bleeding","volume":"41","author":"Hartmann","year":"2003","journal-title":"Z Gastroenterol"},{"key":"10.1016\/j.giec.2006.03.004_bib9","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0016-5107(02)70037-0","article-title":"Capsule endoscopy in the evaluation of patients with suspected small intestinal bleeding: results of a pilot study","volume":"56","author":"Lewis","year":"2002","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib10","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1055\/s-2002-33446","article-title":"The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding","volume":"34","author":"Ell","year":"2002","journal-title":"Endoscopy"},{"key":"10.1016\/j.giec.2006.03.004_bib11","doi-asserted-by":"crossref","first-page":"S83","DOI":"10.1016\/S0002-9270(02)04724-X","article-title":"Comparison of wireless capsule endoscopy (M2A\u2122) with push enteroscopy in the evaluation of obscure gastrointestinal bleeding [abstract]","volume":"97","author":"Lim","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.giec.2006.03.004_bib12","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1365-2036.2004.02067.x","article-title":"Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: a comparative study with push enteroscopy","volume":"20","author":"Mata","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.giec.2006.03.004_bib13","first-page":"A29","article-title":"A comparison between the M2A\u2122 capsule and push enteroscopy for the investigation of obscure gastrointestinal bleeding [abstract]","volume":"16","author":"Selby","year":"2001","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.giec.2006.03.004_bib14","first-page":"AB146","article-title":"Wireless capsule enteroscopy is superior to push enteroscopy for identification of small intestinal source of obscure gastrointestinal bleeding [abstract]","volume":"55","author":"Demedts","year":"2002","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib15","doi-asserted-by":"crossref","first-page":"AB100","DOI":"10.1016\/S0016-5107(04)00503-6","article-title":"Capsule endoscopy (CE) versus push enteroscopy (PE) for obscure gastrointestinal bleeding (OGIB): a randomized, single-blind, cross-over study [abstract]","volume":"59","author":"Saunders","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib16","first-page":"A18","article-title":"Video capsule endoscopy (VCE) for obscure gastrointestinal bleeding (OGIB) and iron deficiency anemia (IDA) [abstract]","volume":"122","author":"Yousfi","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.giec.2006.03.004_bib17","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1055\/s-2003-44583","article-title":"Diagnostic yield of wireless capsule enteroscopy in comparison with computed tomography enteroclysis","volume":"35","author":"Voderholzer","year":"2003","journal-title":"Endoscopy"},{"issue":"2","key":"10.1016\/j.giec.2006.03.004_bib18","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00384-005-0755-0","article-title":"Comparison of capsule endoscopy and magnetic resonance (MR) enteroclysis in suspected small bowel disease","volume":"21","author":"Golder","year":"2006","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.giec.2006.03.004_bib19","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.dld.2004.03.011","article-title":"Wireless capsule video endoscopy compared to barium follow-through and computerised tomography in patients with suspected Crohn's disease: final report","volume":"36","author":"Eliakim","year":"2004","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.giec.2006.03.004_bib20","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1148\/radiol.2381050296","article-title":"Crohn's disease of the small bowel: preliminary comparison of CT enterography, capsule endoscopy, small-bowel follow-through and ileoscopy","volume":"233","author":"Hara","year":"2006","journal-title":"Radiology"},{"key":"10.1016\/j.giec.2006.03.004_bib21","series-title":"Wireless capsule endoscopy is more informative than ileoscopy and SBFT for the evaluation of the small intestine in patients with known or suspected Crohn's disease [abstract]","author":"Bloom","year":"2003"},{"key":"10.1016\/j.giec.2006.03.004_bib22","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1111\/j.1572-0241.2004.40253.x","article-title":"Videocapsule endoscopy versus barium contrast studies for the diagnosis of Crohn's disease recurrence involving the small intestine","volume":"99","author":"Buchman","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.giec.2006.03.004_bib23","doi-asserted-by":"crossref","first-page":"AB173","DOI":"10.1016\/S0016-5107(04)00822-3","article-title":"Wireless capsule enteroscopy: a comparison with enterography, push enteroscopy and ileo-colonoscopy in the diagnosis of small bowel Crohn's disease [abstract]","volume":"59","author":"Toth","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib24","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0016-5107(04)02571-4","article-title":"Capsule endoscopy vs. push enteroscopy and enteroclysis in suspected small-bowel Crohn's disease","volume":"61","author":"Chong","year":"2005","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib25","doi-asserted-by":"crossref","first-page":"AB174","DOI":"10.1016\/S0016-5107(04)00826-0","article-title":"Diagnosing Crohn's disease (CD) of the small bowel (SB): should capsule endoscopy (CE) be used? CE vs. other diagnostic modalities [abstract]","volume":"59","author":"Dubcenco","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib26","doi-asserted-by":"crossref","first-page":"AB177","DOI":"10.1016\/S0016-5107(04)00838-7","article-title":"Wireless capsule endoscopy vs. small bowel enteroclysis in the detection of ileal involvement in Crohn's disease: a prospective controlled trial [abstract]","volume":"59","author":"Marmo","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib27","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1136\/gut.2004.040055","article-title":"Small bowel involvement in Crohn's disease: a prospective comparison of wireless capsule endoscopy and computed tomography enteroclysis","volume":"54","author":"Voderholzer","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.giec.2006.03.004_bib28","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1111\/j.1572-0241.2005.00274.x","article-title":"A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding","volume":"100","author":"Triester","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.giec.2006.03.004_bib29","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1111\/j.1572-0241.2005.00274.x","article-title":"A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding","volume":"100","author":"Triester","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.giec.2006.03.004_bib30","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.giec.2006.03.004_bib31","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.giec.2006.03.004_bib32","series-title":"Prospective controlled trial comparing wireless capsule endoscopy with intraoperative enteroscopy in patients with chronic gastrointestinal bleeding: ongoing multicenter study [abstract]","author":"Bolz","year":"2004"},{"key":"10.1016\/j.giec.2006.03.004_bib33","series-title":"A prospective comparison of mesenteric angiography with wireless capsule endoscopy in the diagnosis of obscure gastrointestinal haemorrhage [abstract]","author":"Ghosh","year":"2004"},{"key":"10.1016\/j.giec.2006.03.004_bib34","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1111\/j.1572-0241.2003.07471.x","article-title":"Wireless capsule endoscopy detects small bowel ulcers in patients with normal results from state of the art enteroclysis","volume":"98","author":"Liangpunsakul","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.giec.2006.03.004_bib35","doi-asserted-by":"crossref","first-page":"AB105","DOI":"10.1016\/S0016-5107(04)00523-1","article-title":"Meta-analysis of capsule endoscopy versus alternative modalities in the diagnosis of small bowel pathologies [abstract]","volume":"59","author":"Lewis","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.giec.2006.03.004_bib36","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1089\/dis.2004.7.292","article-title":"Diagnosing Crohn's disease: an economic analysis comparing wireless capsule endoscopy with traditional diagnostic procedures","volume":"7","author":"Goldfarb","year":"2004","journal-title":"Dis Manage"},{"key":"10.1016\/j.giec.2006.03.004_bib37","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S1542-3565(04)00603-2","article-title":"Visible small-intestinal mucosal injury in chronic NSAID users","volume":"3","author":"Graham","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.giec.2006.03.004_bib38","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S1542-3565(04)00619-6","article-title":"Investigators. Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo","volume":"3","author":"Goldstein","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.giec.2006.03.004_bib39","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1053\/j.gastro.2003.11.057","article-title":"Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases","volume":"126","author":"Pennazio","year":"2004","journal-title":"Gastroenterology"}],"container-title":["Gastrointestinal Endoscopy Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105251570600050X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105251570600050X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T07:13:00Z","timestamp":1760944380000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S105251570600050X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["S105251570600050X"],"URL":"https:\/\/doi.org\/10.1016\/j.giec.2006.03.004","relation":{},"ISSN":["1052-5157"],"issn-type":[{"value":"1052-5157","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Capsule Endoscopy: A Meta-Analysis for Use with Obscure Gastrointestinal Bleeding and Crohn's Disease","name":"articletitle","label":"Article Title"},{"value":"Gastrointestinal Endoscopy Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.giec.2006.03.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}