{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T17:32:32Z","timestamp":1794072752409,"version":"4.8.0"},"reference-count":14,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000871","name":"Mayo Clinic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["gimjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genetics in Medicine"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.gim.2025.101572","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T15:09:03Z","timestamp":1756480143000},"page":"101572","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Two-tiered newborn screening for infantile Krabbe disease allows timely treatment initiation and avoids false-positive results"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9218-6233","authenticated-orcid":false,"given":"Patricia L.","family":"Hall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy L.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn","family":"Peck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Pino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"April","family":"Studinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitar","family":"Gavrilov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devin","family":"Oglesbee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Schultz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Tortorelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dietrich","family":"Matern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.gim.2025.101572_bib2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13023-019-1018-4","article-title":"Early progression of Krabbe disease in patients with symptom onset between 0 and 5 months","volume":"14","author":"Beltran-Quintero","year":"2019","journal-title":"Orphanet J Rare Dis"},{"issue":"1","key":"10.1016\/j.gim.2025.101572_bib3","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s13023-018-0766-x","article-title":"Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease","volume":"13","author":"Kwon","year":"2018","journal-title":"Orphanet J Rare Dis"},{"issue":"1-2","key":"10.1016\/j.gim.2025.101572_bib4","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ymgme.2021.03.016","article-title":"Consensus recommendations for the classification and long-term follow up of infants who screen positive for Krabbe disease","volume":"134","author":"Thompson-Stone","year":"2021","journal-title":"Mol Genet Metab"},{"issue":"6","key":"10.1016\/j.gim.2025.101572_bib5","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1038\/s41436-020-0764-y","article-title":"The critical role of psychosine in screening, diagnosis, and monitoring of Krabbe disease","volume":"22","author":"Guenzel","year":"2020","journal-title":"Genet Med"},{"issue":"1","key":"10.1016\/j.gim.2025.101572_bib6","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3390\/ijns10010010","article-title":"Newborn screening for Krabbe disease: status quo and recommendations for improvements","volume":"10","author":"Matern","year":"2024","journal-title":"Int J Neonatal Screen"},{"issue":"8","key":"10.1016\/j.gim.2025.101572_bib7","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/gim.2017.194","article-title":"Precision newborn screening for lysosomal disorders","volume":"20","author":"Minter Baerg","year":"2018","journal-title":"Genet Med"},{"issue":"4","key":"10.1016\/j.gim.2025.101572_bib8","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s10545-007-0690-z","article-title":"Newborn screening in North America","volume":"30","author":"Therrell","year":"2007","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.gim.2025.101572_bib9","author":"Fauber"},{"key":"10.1016\/j.gim.2025.101572_bib10","author":"Gabler"},{"issue":"1","key":"10.1016\/j.gim.2025.101572_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijns4010001","article-title":"NewSTEPs: the establishment of a national newborn screening technical assistance resource center","volume":"4","author":"Ojodu","year":"2018","journal-title":"Int J Neonatal Screen"},{"issue":"2","key":"10.1016\/j.gim.2025.101572_bib12","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3390\/ijns5020022","article-title":"A newborn screening education best practices framework: development and adoption","volume":"5","author":"Evans","year":"2019","journal-title":"Int J Neonatal Screen"},{"issue":"4","key":"10.1016\/j.gim.2025.101572_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0231050","article-title":"Newborn screening timeliness quality improvement initiative: impact of national recommendations and data repository","volume":"15","author":"Sontag","year":"2020","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.gim.2025.101572_bib14","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1182\/bloodadvances.2021006094","article-title":"Benefits of newborn screening and hematopoietic cell transplant in infantile Krabbe disease","volume":"6","author":"Page","year":"2022","journal-title":"Blood Adv"},{"key":"10.1016\/j.gim.2025.101572_bib15","author":"London"}],"container-title":["Genetics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360025002199?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360025002199?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T23:24:09Z","timestamp":1786663449000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1098360025002199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S1098360025002199"],"URL":"https:\/\/doi.org\/10.1016\/j.gim.2025.101572","relation":{},"ISSN":["1098-3600"],"issn-type":[{"value":"1098-3600","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Two-tiered newborn screening for infantile Krabbe disease allows timely treatment initiation and avoids false-positive results","name":"articletitle","label":"Article Title"},{"value":"Genetics in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gim.2025.101572","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American College of Medical Genetics and Genomics. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101572"}}