{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:39:17Z","timestamp":1792525157722,"version":"4.5.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008376","name":"HUS Helsinki University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008376","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010711","name":"Cancer Foundation Finland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011797","name":"TYKS Turku University Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011797","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001545","name":"Children's Tumor Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001545","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["gimjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genetics in Medicine"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.gim.2026.102715","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:03:03Z","timestamp":1788879783000},"page":"102715","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of a child\u2019s rare disease, neurofibromatosis 1, with parental income and employment trajectories following the child\u2019s birth"],"prefix":"10.1016","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1182-5326","authenticated-orcid":false,"given":"Kristian","family":"G\u00e4stgifvars","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8823-907X","authenticated-orcid":false,"given":"Edvard","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5372-2985","authenticated-orcid":false,"given":"Petri","family":"B\u00f6ckerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0990-1430","authenticated-orcid":false,"given":"Sirkku","family":"Peltonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5732-4167","authenticated-orcid":false,"given":"Juha","family":"Peltonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7512-2980","authenticated-orcid":false,"given":"Roope A.","family":"Kallionp\u00e4\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gim.2026.102715_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jhealeco.2016.12.008","article-title":"Health and work in the family: evidence from spouses\u2019 cancer diagnoses","volume":"52","author":"Jeon","year":"2017","journal-title":"J Health Econ"},{"issue":"1","key":"10.1016\/j.gim.2026.102715_bib2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13643-022-02165-2","article-title":"Economic burden on caregivers or parents with Down syndrome children-a systematic review protocol","volume":"12","author":"Shetty","year":"2023","journal-title":"Syst Rev"},{"issue":"3","key":"10.1016\/j.gim.2026.102715_bib3","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1038\/jid.2014.465","article-title":"Incidence and mortality of neurofibromatosis: a total population study in Finland","volume":"135","author":"Uusitalo","year":"2015","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.gim.2026.102715_bib4","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2017.4","article-title":"Neurofibromatosis type 1","volume":"3","author":"Gutmann","year":"2017","journal-title":"Nat Rev Dis Primers"},{"issue":"5","key":"10.1016\/j.gim.2026.102715_bib5","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1038\/s41436-020-0752-2","article-title":"Examination of the genetic factors underlying the cognitive variability associated with neurofibromatosis type 1","volume":"22","author":"Ottenhoff","year":"2020","journal-title":"Genet Med"},{"issue":"7","key":"10.1016\/j.gim.2026.102715_bib6","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/gim.2018.28","article-title":"Care of adults with neurofibromatosis type 1: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)","volume":"20","author":"Stewart","year":"2018","journal-title":"Genet Med"},{"issue":"5","key":"10.1016\/j.gim.2026.102715_bib7","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2019-0660","article-title":"Health supervision for children with neurofibromatosis Type 1","volume":"143","author":"Miller","year":"2019","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.gim.2026.102715_bib8","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/cge.13907","article-title":"A rare disease and education: neurofibromatosis type 1 decreases educational attainment","volume":"99","author":"Johansson","year":"2021","journal-title":"Clin Genet"},{"issue":"1","key":"10.1016\/j.gim.2026.102715_bib9","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s41431-023-01426-5","article-title":"The contribution of morbidity and unemployment for the reduced labor market participation of individuals with neurofibromatosis 1 in Finland","volume":"32","author":"Kallionp\u00e4\u00e4","year":"2024","journal-title":"Eur J Hum Genet"},{"issue":"2","key":"10.1016\/j.gim.2026.102715_bib10","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/ajmg.a.33139","article-title":"Birth incidence and prevalence of tumor-prone syndromes: estimates from a UK family genetic register service","volume":"152A","author":"Evans","year":"2010","journal-title":"Am J Med Genet A"},{"issue":"11","key":"10.1016\/j.gim.2026.102715_bib11","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1136\/jmg.26.11.704","article-title":"A genetic study of von Recklinghausen neurofibromatosis in south east Wales. I. Prevalence, fitness, mutation rate, and effect of parental transmission on severity","volume":"26","author":"Huson","year":"1989","journal-title":"J Med Genet"},{"issue":"3 Pt 1","key":"10.1016\/j.gim.2026.102715_bib12","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1542\/peds.105.3.608","article-title":"Use of the National Institutes of Health criteria for diagnosis of neurofibromatosis 1 in children","volume":"105","author":"DeBella","year":"2000","journal-title":"Pediatrics"},{"issue":"8","key":"10.1016\/j.gim.2026.102715_bib13","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1038\/s41436-021-01170-5","article-title":"Revised diagnostic criteria for neurofibromatosis type 1 and Legius syndrome: an international consensus recommendation","volume":"23","author":"Legius","year":"2021","journal-title":"Genet Med"},{"key":"10.1016\/j.gim.2026.102715_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2022.101818","article-title":"ERN GENTURIS tumour surveillance guidelines for individuals with neurofibromatosis type 1","volume":"56","author":"Carton","year":"2023","journal-title":"EClinicalMedicine"},{"issue":"1","key":"10.1016\/j.gim.2026.102715_bib15","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1177\/0883073817739509","article-title":"Optic pathway gliomas in neurofibromatosis Type 1","volume":"33","author":"Campen","year":"2018","journal-title":"J Child Neurol"},{"issue":"11","key":"10.1016\/j.gim.2026.102715_bib16","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1002\/ijc.32187","article-title":"Pediatric malignancies in neurofibromatosis type 1: a population-based cohort study","volume":"145","author":"Peltonen","year":"2019","journal-title":"Int J Cancer"},{"issue":"10","key":"10.1016\/j.gim.2026.102715_bib17","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1002\/ajmg.a.33045","article-title":"Skeletal abnormalities in neurofibromatosis type 1: approaches to therapeutic options","volume":"149A","author":"Elefteriou","year":"2009","journal-title":"Am J Med Genet A"},{"issue":"11","key":"10.1016\/j.gim.2026.102715_bib18","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1111\/dmcn.13526","article-title":"Neurodevelopmental disorders in children with neurofibromatosis type 1","volume":"59","author":"Vogel","year":"2017","journal-title":"Dev Med Child Neurol"},{"issue":"7","key":"10.1016\/j.gim.2026.102715_bib19","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/gim.2017.177","article-title":"School liaison program supporting children with neurofibromatosis type 1: a model of care for children with chronic disease","volume":"20","author":"Chambers","year":"2018","journal-title":"Genet Med"},{"issue":"1","key":"10.1016\/j.gim.2026.102715_bib20","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/ajmg.a.64223","article-title":"Parental experiences of receiving a rare genetic disease diagnosis for their child on diagnosis day","volume":"200","author":"Bullock","year":"2026","journal-title":"Am J Med Genet A"},{"issue":"12","key":"10.1016\/j.gim.2026.102715_bib21","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1007\/s40273-023-01308-0","article-title":"Are we capturing the socioeconomic burden of rare genetic disease? A scoping review of economic evaluations and cost-of-illness studies","volume":"41","author":"Marshall","year":"2023","journal-title":"Pharmacoeconomics"},{"issue":"6","key":"10.1016\/j.gim.2026.102715_bib22","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/s41431-019-0359-8","article-title":"Educational delay and attainment in persons with neurofibromatosis 1 in Denmark","volume":"27","author":"Doser","year":"2019","journal-title":"Eur J Hum Genet"},{"issue":"1","key":"10.1016\/j.gim.2026.102715_bib23","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1186\/s13023-023-02965-2","article-title":"Employment, occupation, and income in adults with neurofibromatosis 1 in Denmark: a population- and register-based cohort study","volume":"18","author":"Kenborg","year":"2023","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.gim.2026.102715_bib24","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2024.1398803","article-title":"Long-term distress throughout one\u2019s life: health-related quality of life, economic and caregiver burden of patients with neurofibromatosis type 1 in China","volume":"12","author":"Liang","year":"2024","journal-title":"Front Public Health"},{"key":"10.1016\/j.gim.2026.102715_bib25","series-title":"Mostly Harmless Econometrics: An Empiricist\u2019s Companion","author":"Angrist","year":"2009"},{"issue":"4","key":"10.1016\/j.gim.2026.102715_bib26","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/j.gim.2021.11.024","article-title":"The rare disease neurofibromatosis 1 as a source of hereditary economic inequality: evidence from Finland","volume":"24","author":"Johansson","year":"2022","journal-title":"Genet Med"},{"issue":"3","key":"10.1016\/j.gim.2026.102715_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1257\/app.20170604","article-title":"Family labor supply responses to severe health shocks: evidence from Danish administrative records","volume":"13","author":"Fadlon","year":"2021","journal-title":"Am Econ J Appl Econ"},{"issue":"4","key":"10.1016\/j.gim.2026.102715_bib28","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1215\/00703370-10828906","article-title":"Gender inequality reinforced: the impact of a Child\u2019s health shock on parents\u2019 labor market trajectories","volume":"60","author":"Vaalavuo","year":"2023","journal-title":"Demography"},{"issue":"S","key":"10.1016\/j.gim.2026.102715_bib29","doi-asserted-by":"crossref","first-page":"S152","DOI":"10.3368\/jhr.1222-12698R1","article-title":"Domestic violence reports and the mental health and well-being of victims and their children","volume":"59","author":"Bhuller","year":"2024","journal-title":"J Hum Resour"},{"issue":"5","key":"10.1016\/j.gim.2026.102715_bib30","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/(SICI)1098-2272(1997)14:5<507::AID-GEPI5>3.0.CO;2-Y","article-title":"Paternal age and sporadic neurofibromatosis 1: A case-control study and consideration of the methodologic issues","volume":"14","author":"Bunin","year":"1997","journal-title":"Genet Epidemiol"},{"issue":"3","key":"10.1016\/j.gim.2026.102715_bib31","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/ajmg.a.34413","article-title":"The importance of advanced parental age in the origin of neurofibromatosis type 1","volume":"158A","author":"Snajderova","year":"2012","journal-title":"Am J Med Genet A"},{"issue":"2","key":"10.1016\/j.gim.2026.102715_bib32","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s10689-014-9774-8","article-title":"Parental age and Neurofibromatosis Type 1: a report from the NF1 Patient Registry Initiative","volume":"14","author":"Liu","year":"2015","journal-title":"Fam Cancer"},{"issue":"4","key":"10.1016\/j.gim.2026.102715_bib33","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1002\/mgg3.222","article-title":"The effect of parental age on the presence of de novo mutations\u2014Lessons from neurofibromatosis type I","volume":"4","author":"Dubov","year":"2016","journal-title":"Mol Genet Genomic Med"},{"issue":"17","key":"10.1016\/j.gim.2026.102715_bib34","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1200\/JCO.2015.65.3576","article-title":"Distinctive cancer associations in patients with neurofibromatosis type 1","volume":"34","author":"Uusitalo","year":"2016","journal-title":"J Clin Oncol"},{"issue":"9","key":"10.1016\/j.gim.2026.102715_bib35","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1177\/0883073808316366","article-title":"Impact of neurofibromatosis type 1 on school performance","volume":"23","author":"Krab","year":"2008","journal-title":"J Child Neurol"},{"issue":"3","key":"10.1016\/j.gim.2026.102715_bib36","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1002\/ajmg.b.32414","article-title":"Executive functioning deficits in children with neurofibromatosis type 1: the influence of intellectual and social functioning","volume":"171B","author":"Plasschaert","year":"2016","journal-title":"Am J Med Genet B Neuropsychiatr Genet"}],"container-title":["Genetics in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360026010336?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1098360026010336?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T18:50:24Z","timestamp":1792522224000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1098360026010336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":36,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S1098360026010336"],"URL":"https:\/\/doi.org\/10.1016\/j.gim.2026.102715","relation":{},"ISSN":["1098-3600"],"issn-type":[{"value":"1098-3600","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of a child\u2019s rare disease, neurofibromatosis 1, with parental income and employment trajectories following the child\u2019s birth","name":"articletitle","label":"Article Title"},{"value":"Genetics in Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gim.2026.102715","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of American College of Medical Genetics and Genomics.","name":"copyright","label":"Copyright"}],"article-number":"102715"}}