{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T06:47:35Z","timestamp":1785912455077,"version":"3.56.0"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T00:00:00Z","timestamp":1779321600000},"content-version":"vor","delay-in-days":140,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","award":["R01HG011711"],"award-info":[{"award-number":["R01HG011711"]}],"id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gimopen.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genetics in Medicine Open"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.gimo.2026.104405","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:44:24Z","timestamp":1779900264000},"page":"104405","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Ethical and social implications of implementing polygenic embryo screening into clinical care: A scoping review"],"prefix":"10.1016","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9996-9414","authenticated-orcid":false,"given":"Betty","family":"Cohn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorit","family":"Barlevy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"L\u00e1zaro-Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.gimo.2026.104405_bib1","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/s41576-018-0018-x","article-title":"The personal and clinical utility of polygenic risk scores","volume":"19","author":"Torkamani","year":"2018","journal-title":"Nat Rev Genet"},{"issue":"5","key":"10.1016\/j.gimo.2026.104405_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.gim.2023.100803","article-title":"The clinical application of polygenic risk scores: a points to consider statement of the American College of Medical Genetics and Genomics (ACMG)","volume":"25","author":"Abu-El-Haija","year":"2023","journal-title":"Genet Med"},{"issue":"5","key":"10.1016\/j.gimo.2026.104405_bib4","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/s41431-021-01000-x","article-title":"The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice","volume":"30","author":"Forzano","year":"2022","journal-title":"Eur J Hum Genet"},{"issue":"4","key":"10.1016\/j.gimo.2026.104405_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.gim.2023.101052","article-title":"Clinical utility of polygenic risk scores for embryo selection: a points to consider statement of the American College of Medical Genetics and Genomics (ACMG)","volume":"26","author":"Grebe","year":"2024","journal-title":"Genet Med"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib6","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.fertnstert.2025.10.023","volume":"125","year":"2026","journal-title":"Fertil Steril"},{"issue":"8","key":"10.1016\/j.gimo.2026.104405_bib7","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1002\/ajmg.b.32736","article-title":"International Society of Psychiatric Genetics Ethics Committee: Issues facing us","volume":"180","author":"L\u00e1zaro-Mu\u00f1oz","year":"2019","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"issue":"10","key":"10.1016\/j.gimo.2026.104405_bib8","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/S2215-0366(22)00157-2","article-title":"Concerns about the use of polygenic embryo screening for psychiatric and cognitive traits","volume":"9","author":"Lencz","year":"2022","journal-title":"Lancet Psychiatry"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib9","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1002\/jgc4.1668","article-title":"Clinical genetic counseling and translation considerations for polygenic scores in personalized risk assessments: a Practice Resource from the National Society of Genetic Counselors","volume":"32","author":"Wand","year":"2023","journal-title":"J Genet Couns"},{"key":"10.1016\/j.gimo.2026.104405_bib10","first-page":"463","article-title":"Choosing your \u201chealthiest\u201d embryo after Dobbs: polygenic screening and distinctive challenges for truth in advertising and informed consent","volume":"38","author":"Fox","year":"2024","journal-title":"Harv J Law Technol"},{"key":"10.1016\/j.gimo.2026.104405_bib11","author":"Samuel"},{"issue":"7","key":"10.1016\/j.gimo.2026.104405_bib12","doi-asserted-by":"crossref","first-page":"467","DOI":"10.7326\/M18-0850","article-title":"PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation","volume":"169","author":"Tricco","year":"2018","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.gimo.2026.104405_bib13","series-title":"Principles of Biomedical Ethics","author":"Beauchamp","year":"2013"},{"key":"10.1016\/j.gimo.2026.104405_bib14","series-title":"Thematic Analysis: A Practical Guide","author":"Braun","year":"2022"},{"key":"10.1016\/j.gimo.2026.104405_bib15","first-page":"9.15.1","article-title":"Genetic tests: clinical validity and clinical utility","volume":"81","author":"Burke","year":"2014","journal-title":"Curr Protoc Hum Genet"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib16","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/RD9.0000000000000049","article-title":"A review of pre-implantation genetic testing technologies and applications","volume":"7","author":"Du","year":"2023","journal-title":"Reprod Dev Med"},{"issue":"6","key":"10.1016\/j.gimo.2026.104405_bib17","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.cell.2019.10.033","article-title":"Screening human embryos for polygenic traits has limited utility","volume":"179","author":"Karavani","year":"2019","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib18","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/s41591-022-01735-0","article-title":"Whole-genome risk prediction of common diseases in human preimplantation embryos","volume":"28","author":"Kumar","year":"2022","journal-title":"Nat Med"},{"key":"10.1016\/j.gimo.2026.104405_bib19","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.64716","article-title":"Utility of polygenic embryo screening for disease depends on the selection strategy","volume":"10","author":"Lencz","year":"2021","journal-title":"Elife"},{"issue":"10","key":"10.1016\/j.gimo.2026.104405_bib20","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1038\/s41431-023-01372-2","article-title":"Contributing to the on-going debate around the clinical application of preimplantation embryo selection based on polygenic risk scores (PGT-P)","volume":"31","author":"Makrythanasis","year":"2023","journal-title":"Eur J Hum Genet"},{"issue":"6632","key":"10.1016\/j.gimo.2026.104405_bib21","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1126\/science.ade1083","article-title":"Public views on polygenic screening of embryos","volume":"379","author":"Meyer","year":"2023","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.gimo.2026.104405_bib22","doi-asserted-by":"crossref","DOI":"10.1093\/genetics\/iyac142","article-title":"Gattaca as a lens on contemporary genetics: marking 25 years into the film\u2019s \u201cnot-too-distant\u201d future","volume":"222","author":"Ogbunugafor","year":"2022","journal-title":"Genetics"},{"issue":"7","key":"10.1016\/j.gimo.2026.104405_bib23","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1093\/humrep\/deac110","article-title":"Polygenic embryo screening: four clinical considerations warrant further attention","volume":"37","author":"Pereira","year":"2022","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib24","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3390\/genes12010118","article-title":"Embryo genetics","volume":"12","author":"Rubio","year":"2021","journal-title":"Genes (Basel)"},{"issue":"10","key":"10.1016\/j.gimo.2026.104405_bib25","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1038\/s41431-023-01333-9","article-title":"Limitations, concerns and potential: attitudes of healthcare professionals toward preimplantation genetic testing using polygenic risk scores","volume":"31","author":"Siermann","year":"2023","journal-title":"Eur J Hum Genet"},{"issue":"5","key":"10.1016\/j.gimo.2026.104405_bib26","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1093\/humrep\/deae049","article-title":"Ready for polygenic risk scores? An analysis of regulation of preimplantation genetic testing in European countries","volume":"39","author":"Siermann","year":"2024","journal-title":"Hum Reprod"},{"issue":"8","key":"10.1016\/j.gimo.2026.104405_bib27","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3390\/genes12081105","article-title":"Embryo screening for polygenic disease risk: recent advances and ethical considerations","volume":"12","author":"Tellier","year":"2021","journal-title":"Genes (Basel)"},{"issue":"5","key":"10.1016\/j.gimo.2026.104405_bib28","doi-asserted-by":"crossref","first-page":"A13","DOI":"10.1530\/REP-20-0071","article-title":"Preimplantation genetic testing: preimplantation genetic testing for polygenic disease risk","volume":"160","author":"Treff","year":"2020","journal-title":"Reproduction"},{"issue":"8","key":"10.1016\/j.gimo.2026.104405_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.gim.2024.101155","article-title":"Correspondence on \u201cClinical utility of polygenic risk scores for embryo selection: a points to consider statement of the American College of Medical Genetics and Genomics (ACMG)\u201d by Grebe et al","volume":"26","author":"Widen","year":"2024","journal-title":"Genet Med"},{"issue":"5","key":"10.1016\/j.gimo.2026.104405_bib30","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/humupd\/dmae012","article-title":"Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations","volume":"30","author":"Capalbo","year":"2024","journal-title":"Hum Reprod Update"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib31","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s11673-023-10293-0","article-title":"Islamic perspectives on polygenic testing and selection of IVF embryos (PGT-P) for optimal intelligence and other non-disease-related socially desirable traits","volume":"21","author":"Chin","year":"2024","journal-title":"J Bioeth Inq"},{"issue":"6","key":"10.1016\/j.gimo.2026.104405_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.rbmo.2023.103327","article-title":"Polygenic embryo screening: are there potential maternal and fetal harms?","volume":"47","author":"Ginod","year":"2023","journal-title":"Reprod Biomed Online"},{"issue":"2","key":"10.1016\/j.gimo.2026.104405_bib33","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/s41436-019-0744-2","article-title":"Embryo selection based on polygenic traits is still premature","volume":"22","author":"Grennell","year":"2020","journal-title":"Genet Med"},{"issue":"8","key":"10.1016\/j.gimo.2026.104405_bib34","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.3390\/jpm12081266","article-title":"The false dawn of polygenic risk scores for human disease prediction","volume":"12","author":"Herzig","year":"2022","journal-title":"J Pers Med"},{"issue":"9","key":"10.1016\/j.gimo.2026.104405_bib35","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1080\/14737159.2024.2390187","article-title":"The current clinical applications of preimplantation genetic testing (PGT): acknowledging the limitations of biology and technology","volume":"24","author":"Kakourou","year":"2024","journal-title":"Expert Rev Mol Diagn"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib36","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1080\/15265161.2023.2169399","article-title":"Bioethicists are not so divided on reproductive testing for non-medical traits: emerging perspectives on polygenic scores","volume":"23","author":"Kamenova","year":"2023","journal-title":"Am J Bioeth"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib37","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1038\/s41436-020-01019-3","article-title":"Screening embryos for polygenic conditions and traits: ethical considerations for an emerging technology","volume":"23","author":"L\u00e1zaro-Mu\u00f1oz","year":"2021","journal-title":"Genet Med"},{"key":"10.1016\/j.gimo.2026.104405_bib38","article-title":"Avoid \u201cunproven and unethical\u201d polygenic risk scores in embryo selection, say genetics experts","volume":"376","author":"Mahase","year":"2022","journal-title":"BMJ"},{"key":"10.1016\/j.gimo.2026.104405_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpeds.2023.113735","article-title":"Social and behavioral genomics: what does it mean for pediatrics?","volume":"264","author":"Martschenko","year":"2024","journal-title":"J Pediatr"},{"issue":"12","key":"10.1016\/j.gimo.2026.104405_bib40","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1136\/medethics-2020-106588","article-title":"Three models for the regulation of polygenic scores in reproduction","volume":"47","author":"Munday","year":"2021","journal-title":"J Med Ethics"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib41","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s12910-021-00694-4","article-title":"Polygenic risk scoring of human embryos: a qualitative study of media coverage","volume":"22","author":"Pagnaer","year":"2021","journal-title":"BMC Med Ethics"},{"issue":"10","key":"10.1016\/j.gimo.2026.104405_bib42","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1093\/humrep\/deac159","article-title":"Polygenic risk score for embryo selection-not ready for prime time","volume":"37","author":"Polyakov","year":"2022","journal-title":"Hum Reprod"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12687-021-00573-w","article-title":"A systematic review of the views of healthcare professionals on the scope of preimplantation genetic testing","volume":"13","author":"Siermann","year":"2022","journal-title":"J Community Genet"},{"issue":"7","key":"10.1016\/j.gimo.2026.104405_bib44","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1007\/s10815-024-03169-8","article-title":"Polygenic embryo screening: quo vadis?","volume":"41","author":"Siermann","year":"2024","journal-title":"J Assist Reprod Genet"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.rbmo.2024.104294","article-title":"Perspectives of preimplantation genetic testing patients in Belgium on the ethics of polygenic embryo screening","volume":"49","author":"Siermann","year":"2024","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.gimo.2026.104405_bib46","doi-asserted-by":"crossref","first-page":"845","DOI":"10.3389\/fendo.2019.00845","article-title":"Utility and first clinical application of screening embryos for polygenic disease risk reduction","volume":"10","author":"Treff","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib47","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1057\/s41292-023-00313-y","article-title":"Conceptualization of genotype-phenotype relationships and the assessment of risk in advertising of direct-to-consumer and preimplantation polygenic tests","volume":"19","author":"Zappala","year":"2024","journal-title":"BioSocieties"},{"issue":"suppl 5","key":"10.1016\/j.gimo.2026.104405_bib48","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/humrep\/15.suppl_5.111","article-title":"The genetic revolution in artificial reproduction: a view of the future","volume":"15","author":"Brenner","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1016\/j.gimo.2026.104405_bib49","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.73193","article-title":"What\u2019s the use?","volume":"10","author":"Fletcher","year":"2021","journal-title":"Elife"},{"issue":"18","key":"10.1016\/j.gimo.2026.104405_bib50","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1056\/NEJMc2113013","article-title":"Use of polygenic scores to select embryos","volume":"385","author":"Kumar","year":"2021","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib51","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1056\/NEJMsr2105065","article-title":"Problems with using polygenic scores to select embryos","volume":"385","author":"Turley","year":"2021","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.gimo.2026.104405_bib52","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1136\/jme-2023-109195","article-title":"Regulatory safeguards needed if preimplantation genetic testing for polygenic risk scores (PGT-P) is permitted in Singapore","volume":"52","author":"Chin","year":"2026","journal-title":"J Med Ethics"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib53","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1055\/s-0044-1782618","article-title":"Preimplantation genetic testing for polygenetic conditions: A legal, ethical, and scientific challenge","volume":"42","author":"Ginod","year":"2024","journal-title":"Semin Reprod Med"},{"issue":"5","key":"10.1016\/j.gimo.2026.104405_bib54","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1007\/s10815-024-03074-0","article-title":"Patient interest in and clinician reservations on polygenic embryo screening: a qualitative study of stakeholder perspectives","volume":"41","author":"Barlevy","year":"2024","journal-title":"J Assist Reprod Genet"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib55","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1086\/725832","article-title":"Shared futures or Financialized futures: polygenic screening, reproductive justice, and the radical charge of collective care","volume":"49","author":"Denbow","year":"2023","journal-title":"Signs J Women Cult Soc"},{"issue":"5","key":"10.1016\/j.gimo.2026.104405_bib56","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.10832","article-title":"Public attitudes, interests, and concerns regarding polygenic embryo screening","volume":"7","author":"Furrer","year":"2024","journal-title":"JAMA Netw Open"},{"issue":"4","key":"10.1016\/j.gimo.2026.104405_bib57","first-page":"186","article-title":"The biology of mental disorders: progress at last","volume":"152","author":"Hyman","year":"2023","journal-title":"D\u00e6dalus"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib58","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1080\/15265161.2023.2169391","article-title":"Genomic uncertainty as a burden for reproductive choice? The problem of probabilistic causation in non-invasive prenatal testing","volume":"23","author":"Rueda","year":"2023","journal-title":"Am J Bioeth"},{"key":"10.1016\/j.gimo.2026.104405_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.intell.2021.101530","article-title":"Using DNA to predict intelligence","volume":"86","author":"von Stumm","year":"2021","journal-title":"Intelligence"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib60","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/bioe.12585","article-title":"Great minds think different: preserving cognitive diversity in an age of gene editing","volume":"34","author":"Anomaly","year":"2020","journal-title":"Bioethics"},{"issue":"3","key":"10.1016\/j.gimo.2026.104405_bib61","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/s41591-022-01743-0","article-title":"Polygenic embryo testing: understated ethics, unclear utility","volume":"28","author":"Johnston","year":"2022","journal-title":"Nat Med"},{"issue":"6","key":"10.1016\/j.gimo.2026.104405_bib62","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/j.fertnstert.2022.03.019","article-title":"Scientific and ethical considerations in using preimplantation genetic testing for polygenic disease","volume":"117","author":"Komorowski","year":"2022","journal-title":"Fertil Steril"},{"key":"10.1016\/j.gimo.2026.104405_bib63","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/978-1-0716-2205-6_15","article-title":"From genotype to phenotype: polygenic prediction of complex human traits","volume":"2467","author":"Raben","year":"2022","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.gimo.2026.104405_bib64","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3389\/fendo.2019.00154","article-title":"Past, present, and future strategies for enhanced assessment of embryo\u2019s genome and reproductive competence in women of advanced reproductive age","volume":"10","author":"Poli","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"5-6","key":"10.1016\/j.gimo.2026.104405_bib65","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/1467-8519.00251","article-title":"Procreative beneficence: why we should select the best children","volume":"15","author":"Savulescu","year":"2001","journal-title":"Bioethics"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib66","first-page":"14","article-title":"Polygenic risk scoring in the human embryo: reproductive genetics, final frontier?","volume":"1","author":"Treff","year":"2020","journal-title":"F S Sci"},{"issue":"1","key":"10.1016\/j.gimo.2026.104405_bib67","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.rbmo.2023.03.013","article-title":"Acceptance of genetic editing and of whole genome sequencing of human embryos by patients with infertility before and after the onset of the COVID-19 pandemic","volume":"47","author":"Neuhausser","year":"2023","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.gimo.2026.104405_bib68","author":"Donohue"},{"key":"10.1016\/j.gimo.2026.104405_bib70","author":"Anomaly"},{"issue":"2","key":"10.1016\/j.gimo.2026.104405_bib71","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s11191-012-9556-3","article-title":"What was wrong with eugenics? Conflicting narratives and disputed interpretations","volume":"23","author":"Paul","year":"2014","journal-title":"Sci Educ"},{"key":"10.1016\/j.gimo.2026.104405_bib72","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.socscimed.2014.02.025","article-title":"The expressivist objection to prenatal testing: the experiences of families living with genetic disease","volume":"107","author":"Boardman","year":"2014","journal-title":"Soc Sci Med"},{"key":"10.1016\/j.gimo.2026.104405_bib73","series-title":"Encyclopedia of Life Sciences","article-title":"Disability and genetics: a disability critique of pre-natal testing and pre-implantation genetic diagnosis (PGD)","author":"Asch","year":"2012"},{"key":"10.1016\/j.gimo.2026.104405_bib74","series-title":"Quality of Life and Human Difference: Genetic Testing, Health Care, and Disability","first-page":"172","article-title":"Where is the sin in synecdoche? Prenatal testing and the parent-child relationship","author":"Asch","year":"2005"},{"issue":"6","key":"10.1016\/j.gimo.2026.104405_bib75","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1111\/1467-9566.13559","article-title":"Expressivist objections to prenatal screening and testing: perceptions of people living with disability","volume":"45","author":"Boardman","year":"2023","journal-title":"Sociol Health Illn"},{"issue":"4","key":"10.1016\/j.gimo.2026.104405_bib76","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1136\/jme.2002.002634","article-title":"Disability, identity and the \u201cexpressivist objection.\u201d","volume":"30","author":"Edwards","year":"2004","journal-title":"J Med Ethics"},{"key":"10.1016\/j.gimo.2026.104405_bib77","series-title":"The Stanford Encyclopedia of Philosophy","article-title":"Feminist bioethics","author":"Scully","year":"2023"}],"container-title":["Genetics in Medicine Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2949774426009155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2949774426009155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T06:03:36Z","timestamp":1785909816000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2949774426009155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":75,"alternative-id":["S2949774426009155"],"URL":"https:\/\/doi.org\/10.1016\/j.gimo.2026.104405","relation":{},"ISSN":["2949-7744"],"issn-type":[{"value":"2949-7744","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ethical and social implications of implementing polygenic embryo screening into clinical care: A scoping review","name":"articletitle","label":"Article Title"},{"value":"Genetics in Medicine Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gimo.2026.104405","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of American College of Medical Genetics and Genomics.","name":"copyright","label":"Copyright"}],"article-number":"104405"}}