{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,19]],"date-time":"2026-04-19T08:06:29Z","timestamp":1776585989589,"version":"3.51.2"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gynecologic Oncology Reports"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.gore.2025.101767","type":"journal-article","created":{"date-parts":[[2025,5,18]],"date-time":"2025-05-18T21:57:26Z","timestamp":1747605446000},"page":"101767","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Outpatient hybrid intracavitary-interstitial brachytherapy for cervical cancer with minimal sedation in a freestanding setting"],"prefix":"10.1016","volume":"59","author":[{"given":"Ngoc-Anh","family":"Le","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyamal","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavin","family":"Mutyala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayan","family":"Issac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhuvi","family":"Mamtani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lyndsay","family":"Willmott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.gore.2025.101767_b0005","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00428-023-03552-3","article-title":"ESGO\/ESTRO\/ESP Guidelines for the management of patients with cervical cancer - Update 2023","volume":"482","author":"Cibula","year":"2023","journal-title":"Virchows Arch."},{"issue":"5","key":"10.1016\/j.gore.2025.101767_b0010","doi-asserted-by":"crossref","first-page":"391","DOI":"10.5114\/jcb.2016.62938","article-title":"The role of interstitial brachytherapy in the management of primary radiation therapy for uterine cervical cancer","volume":"8","author":"Murakami","year":"2016","journal-title":"J Contemp Brachytherapy."},{"issue":"2","key":"10.1016\/j.gore.2025.101767_b0015","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.ijrobp.2009.10.075","article-title":"Gyn IMRT Consortium: Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy for the definitive treatment of cervix cancer","volume":"79","author":"Lim","year":"2011","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"7","key":"10.1016\/j.gore.2025.101767_b0020","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.3109\/0284186X.2013.818253","article-title":"MRI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective","volume":"52","author":"Lindegaard","year":"2013","journal-title":"Acta Oncol."},{"issue":"1","key":"10.1016\/j.gore.2025.101767_b0025","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.radonc.2011.07.012","article-title":"Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer","volume":"100","author":"P\u00f6tter","year":"2011","journal-title":"Radiother. Oncol."},{"issue":"3","key":"10.1016\/j.gore.2025.101767_b0030","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.radonc.2012.04.007","article-title":"Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: results of the French STIC prospective study","volume":"103","author":"Charra-Brunaud","year":"2012","journal-title":"Radiother. Oncol."},{"issue":"2","key":"10.1016\/j.gore.2025.101767_b0035","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ygyno.2014.08.027","article-title":"Improved survival of patients with cervical cancer treated with image-guided brachytherapy compared with conventional brachytherapy","volume":"135","author":"Rijkmans","year":"2014","journal-title":"Gynecol. Oncol."},{"issue":"3","key":"10.1016\/j.gore.2025.101767_b0040","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.radonc.2004.12.015","article-title":"Gynaecological (GYN) GEC-ESTRO Working Group. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV","volume":"74","author":"Haie-Meder","year":"2005","journal-title":"Radiother. Oncol."},{"issue":"1","key":"10.1016\/j.gore.2025.101767_b0045","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.radonc.2005.11.014","volume":"78","author":"P\u00f6tter","year":"2006","journal-title":"Radiother. Oncol."},{"issue":"2","key":"10.1016\/j.gore.2025.101767_b0050","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.ijrobp.2006.01.036","article-title":"The Vienna applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: design, application, treatment planning, and dosimetric results","volume":"65","author":"Kirisits","year":"2006","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"3","key":"10.1016\/j.gore.2025.101767_b0055","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.radonc.2016.03.020","article-title":"Image guided adaptive brachytherapy with combined intracavitary and interstitial technique improves the therapeutic ratio in locally advanced cervical cancer: analysis from the retroEMBRACE study","volume":"120","author":"Fokdal","year":"2016","journal-title":"Radiother. Oncol."},{"issue":"1","key":"10.1016\/j.gore.2025.101767_b0060","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0360-3016(00)00497-1","article-title":"The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix","volume":"48","author":"Nag","year":"2000","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"4","key":"10.1016\/j.gore.2025.101767_b0065","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.ijrobp.2008.03.032","article-title":"Image-guided radiotherapy for cervix cancer: high-tech external beam therapy versus high-tech brachytherapy","volume":"71","author":"Georg","year":"2008","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"6","key":"10.1016\/j.gore.2025.101767_b0070","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.brachy.2020.08.018","article-title":"Development, implementation, and associated challenges of a new HDR brachytherapy program","volume":"19","author":"Scanderbeg","year":"2020","journal-title":"Brachytherapy."},{"issue":"12","key":"10.1016\/j.gore.2025.101767_b0075","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1016\/j.jval.2022.03.025","article-title":"Disparities in access to radiation therapy by race and ethnicity in the united states with focus on american indian\/alaska native people","volume":"25","author":"Amiri","year":"2022","journal-title":"Value Health."},{"issue":"2","key":"10.1016\/j.gore.2025.101767_b0080","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.ijrobp.2021.08.038","article-title":"Disparities in access to radiation therapy facilities among American Indians\/Alaska Natives and Hispanics in Washington State","volume":"112","author":"Greer","year":"2022","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"1","key":"10.1016\/j.gore.2025.101767_b0085","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.brachy.2021.05.004","article-title":"Geographic access to brachytherapy services in the United States","volume":"21","author":"Bates","year":"2022","journal-title":"Brachytherapy."},{"issue":"1","key":"10.1016\/j.gore.2025.101767_b0090","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ygyno.2018.04.563","article-title":"Underutilization of brachytherapy and disparities in survival for patients with cervical cancer in California","volume":"150","author":"Mayadev","year":"2018","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.gore.2025.101767_b0095","doi-asserted-by":"crossref","unstructured":"World Medical Association. World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects. Nurs Ethics. 2002;9(1):105-109. doi:10.1191\/0969733002ne486xx.","DOI":"10.1191\/0969733002ne486xx"},{"key":"10.1016\/j.gore.2025.101767_b0100","unstructured":"Statement on Continuum of depth of sedation: definition of general anesthesia and levels of sedation\/analgesia. American Society of Anesthesiologists. Available from: https:\/\/www.asahq.org\/standards-and-practice-parameters\/statement-on-continuum-of-depth-of-sedation-definition-of-general-anesthesia-and-levels-of-sedation-analgesia [accessed on 2024 Dec 28]."},{"issue":"1","key":"10.1016\/j.gore.2025.101767_b0105","doi-asserted-by":"crossref","first-page":"43","DOI":"10.5114\/jcb.2023.125527","article-title":"Feasibility of outpatient hybrid brachytherapy for cervical cancer with minimal sedation: results from a single-institutional protocol","volume":"15","author":"Mutyala","year":"2023","journal-title":"J. Contemp. Brachytherapy."},{"issue":"3","key":"10.1016\/j.gore.2025.101767_b0110","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.brachy.2020.01.006","article-title":"Anesthetic and analgesic methods for gynecologic brachytherapy: a meta-analysis and systematic review","volume":"19","author":"Petitt","year":"2020","journal-title":"Brachytherapy"},{"issue":"5","key":"10.1016\/j.gore.2025.101767_b0115","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/01.coc.0000128723.00352.ad","article-title":"A study of complications arising from different methods of anesthesia used in high-dose-rate brachytherapy for cervical cancer","volume":"27","author":"Lim","year":"2004","journal-title":"Am. J. Clin. Oncol."},{"issue":"9","key":"10.1016\/j.gore.2025.101767_b0120","doi-asserted-by":"crossref","first-page":"e403","DOI":"10.1016\/j.clon.2021.02.011","article-title":"Ultrasound-guided Brachytherapy for Cervix Cancer","volume":"33","author":"van Dyk","year":"2021","journal-title":"Clin. Oncol. (R Coll Radiol)."},{"issue":"2","key":"10.1016\/j.gore.2025.101767_b0125","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.radonc.2010.01.001","article-title":"From point A to the sculpted pear: MR image guidance significantly improves tumour dose and sparing of organs at risk in brachytherapy of cervical cancer","volume":"94","author":"Tanderup","year":"2010","journal-title":"Radiother. Oncol."},{"issue":"2","key":"10.1016\/j.gore.2025.101767_b0130","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ijrobp.2014.02.018","article-title":"Posttraumatic stress disorder after high-dose-rate brachytherapy for cervical cancer with 2 fractions in 1 application under spinal\/epidural anesthesia: incidence and risk factors","volume":"89","author":"Kirchheiner","year":"2014","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"1250","key":"10.1016\/j.gore.2025.101767_b0135","first-page":"255","article-title":"International brachytherapy practice patterns: a survey of the Gynecologic Cancer Intergroup (GCIG)","volume":"82","author":"Viswanathan","year":"2012","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."}],"container-title":["Gynecologic Oncology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235257892500092X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235257892500092X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T03:06:10Z","timestamp":1750215970000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S235257892500092X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":27,"alternative-id":["S235257892500092X"],"URL":"https:\/\/doi.org\/10.1016\/j.gore.2025.101767","relation":{},"ISSN":["2352-5789"],"issn-type":[{"value":"2352-5789","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outpatient hybrid intracavitary-interstitial brachytherapy for cervical cancer with minimal sedation in a freestanding setting","name":"articletitle","label":"Article Title"},{"value":"Gynecologic Oncology Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gore.2025.101767","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101767"}}