{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:36:42Z","timestamp":1792039002633,"version":"4.4.0"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015401","name":"Shaanxi Province Key Research and Development Projects","doi-asserted-by":"publisher","award":["2024SF-YBXM-133"],"award-info":[{"award-number":["2024SF-YBXM-133"]}],"id":[{"id":"10.13039\/501100015401","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gynecologic Oncology Reports"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.gore.2026.102139","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T06:39:04Z","timestamp":1781159944000},"page":"102139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Recurrent epithelioid trophoblastic tumor with complete response after surgery, chemotherapy, and immunotherapy: A case report and literature review"],"prefix":"10.1016","volume":"66","author":[{"given":"Lingting","family":"Meng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ye","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gore.2026.102139_bb0005","article-title":"An extrauterine extensively metastatic epithelioid trophoblastic tumor responsive to pembrolizumab","volume":"37","author":"Bell","year":"2021","journal-title":"Gynecol. Oncol. Rep."},{"key":"10.1016\/j.gore.2026.102139_bb0010","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1097\/IGC.0000000000000892","article-title":"PD-L1 expression in premalignant and malignant trophoblasts from gestational trophoblastic diseases is ubiquitous and independent of clinical outcomes","volume":"27","author":"Bolze","year":"2017","journal-title":"Int. J. Gynecol. Cancer"},{"key":"10.1016\/j.gore.2026.102139_bb0015","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ejca.2019.08.024","article-title":"Effective anti-programmed cell death 1 treatment for chemoresistant gestational trophoblastic neoplasia","volume":"121","author":"Choi","year":"2019","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.gore.2026.102139_bb0020","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.ygyno.2015.03.006","article-title":"Epithelioid trophoblastic tumor: a single institution case series at the New England Trophoblastic Disease Center","volume":"137","author":"Davis","year":"2015","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.gore.2026.102139_bb0025","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.ygyno.2018.11.015","article-title":"Management and prognostic factors of epithelioid trophoblastic tumors: Results from the International Society for the Study of Trophoblastic Diseases database","volume":"152","author":"Frijstein","year":"2019","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.gore.2026.102139_bb0030","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1016\/S0140-6736(17)32894-5","article-title":"Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia","volume":"390","author":"Ghorani","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.gore.2026.102139_bb0035","article-title":"Primary hepatic metastatic epitheloid trophoblastic tumor of the uterus treated with multimodal therapy including pembrolizumab and thermoablation. Case report of an extremely rare disease and review of the literature","volume":"49","author":"Helbig","year":"2023","journal-title":"Gynecol. Oncol. Rep."},{"key":"10.1016\/j.gore.2026.102139_bb0040","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ygyno.2016.10.024","article-title":"Placental site trophoblastic tumors and epithelioid trophoblastic tumors: biology, natural history, and treatment modalities","volume":"144","author":"Horowitz","year":"2017","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.gore.2026.102139_bb0045","first-page":"31","article-title":"Deeper understanding of epithelioid trophoblastic tumor","volume":"9","author":"Jiang","year":"2018","journal-title":"Med. J. Peking Union Med. College Hospit."},{"key":"10.1016\/j.gore.2026.102139_bb0050","article-title":"A multicenter retrospective study of epithelioid trophoblastic tumors to identify the outcomes, prognostic factors, and therapeutic strategies","volume":"12","author":"Liu","year":"2022","journal-title":"Front. Oncol."},{"key":"10.1016\/j.gore.2026.102139_bb0055","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ejca.2020.02.011","article-title":"Practical clinical guidelines of the EOTTD for treatment and referral of gestational trophoblastic disease","volume":"130","author":"Lok","year":"2020","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.gore.2026.102139_bb0060","first-page":"649","article-title":"Introduction of WHO classification of tumours of female reproductive organs, fourth edition","volume":"43","author":"Lu","year":"2014","journal-title":"Zhonghua Bing Li Xue Za Zhi"},{"key":"10.1016\/j.gore.2026.102139_bb0065","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ygyno.2007.11.015","article-title":"Diagnostic challenges in extrauterine epithelioid trophoblastic tumours: a report of two cases","volume":"108","author":"Macdonald","year":"2008","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.gore.2026.102139_bb0070","doi-asserted-by":"crossref","first-page":"50","DOI":"10.6118\/jmm.2016.22.1.50","article-title":"Epithelioid trophoblastic tumor in a postmenopausal woman: a case report","volume":"22","author":"Park","year":"2016","journal-title":"J. Menopausal. Med."},{"key":"10.1016\/j.gore.2026.102139_bb0075","doi-asserted-by":"crossref","first-page":"5346","DOI":"10.3390\/curroncol28060446","article-title":"Epithelioid trophoblastic tumour: a case with genetic linkage to a child born over seventeen years prior, successfully treated with surgery and pembrolizumab","volume":"28","author":"Pisani","year":"2021","journal-title":"Curr. Oncol."},{"key":"10.1016\/j.gore.2026.102139_bb0080","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1097\/GME.0000000000000908","article-title":"Two cases of epithelioid trophoblastic tumors in postmenopausal women","volume":"24","author":"Rodr\u00edguez-Trujillo","year":"2017","journal-title":"Menopause"},{"key":"10.1016\/j.gore.2026.102139_bb0085","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/ajcp\/aqy039","article-title":"A case series of five patients with pure or mixed gestational epithelioid trophoblastic tumors and a literature review on mixed tumors","volume":"150","author":"Tse","year":"2018","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.gore.2026.102139_bb0090","first-page":"1","article-title":"Advancing immunotherapy in gestational trophoblastic neoplasia: current progress and future directions","volume":"5","author":"Wang","year":"2025","journal-title":"Gynecol. Obstetr. Clin. Med."},{"key":"10.1016\/j.gore.2026.102139_bb0095","first-page":"8245","article-title":"Epithelioid trophoblastic tumor after induced abortion with previous broad choriocarcinoma: a case report and review of literature","volume":"7","author":"Zhang","year":"2014","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.gore.2026.102139_bb0100","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1007\/s00404-018-05037-0","article-title":"Intermediate trophoblastic tumor: the clinical analysis of 62 cases and prognostic factors","volume":"299","author":"Zhang","year":"2019","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.gore.2026.102139_bb0105","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/his.13882","article-title":"PD-L1, B7-H3 and VISTA are highly expressed in gestational trophoblastic neoplasia","volume":"75","author":"Zong","year":"2019","journal-title":"Histopathology"}],"container-title":["Gynecologic Oncology Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352578926001190?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352578926001190?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T04:47:04Z","timestamp":1787287624000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352578926001190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":21,"alternative-id":["S2352578926001190"],"URL":"https:\/\/doi.org\/10.1016\/j.gore.2026.102139","relation":{},"ISSN":["2352-5789"],"issn-type":[{"value":"2352-5789","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recurrent epithelioid trophoblastic tumor with complete response after surgery, chemotherapy, and immunotherapy: A case report and literature review","name":"articletitle","label":"Article Title"},{"value":"Gynecologic Oncology Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.gore.2026.102139","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"102139"}}