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Knowledge of the primary structure of antimicrobial agents and their activities is essential for rational drug design. Thus, we developed a comprehensive database, anti microbial drug database (AMDD), of known synthetic antibacterial and antifungal compounds that were extracted from the available literature and other chemical databases, e.g., PubChem, PubChem BioAssay and ZINC, etc. The current version of AMDD contains \u223c2900 antibacterial and \u223c1200 antifungal compounds. The molecules are annotated with properties such as description, target, format, bioassay, molecular weight, hydrogen bond donor, hydrogen bond acceptor and rotatable bond. The availability of these antimicrobial agents on common platform not only provides useful information but also facilitate the virtual screening process, thus saving time and overcoming difficulties in selecting specific type of inhibitors for the specific targets. AMDD may provide a more effective and efficient way of accessing antimicrobial compounds based on their properties along with the links to their structure and bioassay. All the compounds are freely available at the advanced web-based search interface http:\/\/www.amddatabase.info.<\/jats:p>","DOI":"10.1016\/j.gpb.2012.04.002","type":"journal-article","created":{"date-parts":[[2012,11,8]],"date-time":"2012-11-08T00:34:56Z","timestamp":1352334896000},"page":"360-363","source":"Crossref","is-referenced-by-count":16,"title":["AMDD: Antimicrobial Drug Database"],"prefix":"10.1093","volume":"10","author":[{"given":"Mohd","family":"Danishuddin","sequence":"first","affiliation":[{"name":"Interdisciplinary Biotechnology Unit, Aligarh Muslim University , Aligarh, 202002 , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lalima","family":"Kaushal","sequence":"additional","affiliation":[{"name":"Interdisciplinary Biotechnology Unit, Aligarh Muslim University , Aligarh, 202002 , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd","family":"Hassan Baig","sequence":"additional","affiliation":[{"name":"Interdisciplinary Biotechnology Unit, Aligarh Muslim University , Aligarh, 202002 , India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asad U.","family":"Khan","sequence":"additional","affiliation":[{"name":"Interdisciplinary Biotechnology Unit, Aligarh Muslim University , Aligarh, 202002 , India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,11,7]]},"reference":[{"key":"2024051008312324300_bib1","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1099\/jmm.0.039008-0","article-title":"NDM-1-producing Enterobacter cloacae and Klebsiella pneumoniae from diabetic foot ulcers in India","volume":"61","author":"Khan","year":"2012","journal-title":"J Med Microbiol"},{"key":"2024051008312324300_bib2","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S1995-7645(12)60003-0","article-title":"Prevalence of plasmid mediated bla (TEM-1) and bla (CTX-M-15) type extended spectrum beta-lactamases in patients with sepsis","volume":"5","author":"Haque","year":"2012","journal-title":"Asian Pac J Trop Med"},{"key":"2024051008312324300_bib3","doi-asserted-by":"crossref","first-page":"D774","DOI":"10.1093\/nar\/gkp1021","article-title":"CAMP: a useful resource for research on antimicrobial peptides","volume":"38","author":"Thomas","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"2024051008312324300_bib4","doi-asserted-by":"crossref","first-page":"D933","DOI":"10.1093\/nar\/gkn823","article-title":"APD2: the updated antimicrobial peptide database and its application in peptide design","volume":"37","author":"Wang","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"2024051008312324300_bib5","doi-asserted-by":"crossref","first-page":"D963","DOI":"10.1093\/nar\/gkn655","article-title":"PhytAMP: a database dedicated to antimicrobial plant peptides","volume":"37","author":"Hammami","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"2024051008312324300_bib6","doi-asserted-by":"crossref","first-page":"D586","DOI":"10.1093\/nar\/gkh032","article-title":"ANTIMIC: a database of antimicrobial sequences","volume":"32","author":"Brahmachary","year":"2004","journal-title":"Nucleic Acids Res"},{"key":"2024051008312324300_bib7","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S1357-4310(99)01490-2","article-title":"Antibiotic peptides from higher eukaryotes: biology and applications","volume":"5","author":"Ganz","year":"1999","journal-title":"Mol Med Today"},{"key":"2024051008312324300_bib8","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1021\/ci049714+","article-title":"ZINC \u2013 a free database of commercially available compounds for virtual screening","volume":"45","author":"Irwin","year":"2005","journal-title":"J Chem Inf Model"},{"key":"2024051008312324300_bib9","doi-asserted-by":"crossref","first-page":"4133","DOI":"10.1093\/bioinformatics\/bti683","article-title":"ChemDB: a public database of small molecules and related chemoinformatics resources","volume":"21","author":"Chen","year":"2005","journal-title":"Bioinformatics"},{"key":"2024051008312324300_bib10","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0166-1280(97)00179-6","article-title":"WWW-based chemical information system","volume":"419","author":"Ertl","year":"1997","journal-title":"J Mol Struct: THEOCHEM"}],"container-title":["Genomics, Proteomics &amp; 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