{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T03:39:55Z","timestamp":1784259595254,"version":"3.55.0"},"reference-count":94,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Clinics of North America"],"published-print":{"date-parts":[[2007,9]]},"DOI":"10.1016\/j.gtc.2007.07.014","type":"journal-article","created":{"date-parts":[[2008,1,9]],"date-time":"2008-01-09T23:43:14Z","timestamp":1199922194000},"page":"577-599","source":"Crossref","is-referenced-by-count":49,"title":["The Many Manifestations of Gastroesophageal Reflux Disease: Presentation, Evaluation, and Treatment"],"prefix":"10.1016","volume":"36","author":[{"given":"Joel E.","family":"Richter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.gtc.2007.07.014_bib1","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1111\/j.1572-0241.2006.00723.x","article-title":"The burden of gastrointestinal and liver diseases, 2006","volume":"101","author":"Shaheen","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib2","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1111\/j.1572-0241.2006.00630.x","article-title":"The Montreal definition and classification of gastroesophageal reflux disease: a global evidence based consensus","volume":"101","author":"Vakil","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib3","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/gut.2004.051821","article-title":"Epidemiology of gastro-oesophageal reflux disease: a systematic review","volume":"54","author":"Dent","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.cgh.2006.09.016","article-title":"Time trends of gastroesophageal reflux disease: a systematic review","volume":"5","author":"El-Serag","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2007.07.014_bib5","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/00365520510011579","article-title":"High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: a Kalixandra study report","volume":"40","author":"Ronkainen","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib6","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1016\/S0016-5085(97)70025-8","article-title":"Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmstead County, Minnesota","volume":"112","author":"Locke","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib7","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1053\/j.gastro.2003.12.001","article-title":"Heartburn severity underestimates erosive esophagitis severity in elderly patients with gastroesophageal reflux disease","volume":"126","author":"Johnson","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib8","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1093\/aje\/kwi218","article-title":"Ethnicity, gender and socioeconomic status as risk factors for esophagitis and Barrett's esophagus","volume":"162","author":"Ford","year":"2005","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.gtc.2007.07.014_bib9","doi-asserted-by":"crossref","first-page":"199","DOI":"10.7326\/0003-4819-143-3-200508020-00006","article-title":"Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications","volume":"143","author":"Howard","year":"2005","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib10","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1056\/NEJMoa054391","article-title":"Body-mass index and symptoms of gastroesophageal reflux in women","volume":"354","author":"Jacobson","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib11","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1111\/j.1572-0241.2006.00849.x","article-title":"Body mass index and gastroesophageal reflux disease: a systematic review and meta-analysis","volume":"108","author":"Corley","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib12","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/gut.43.3.327","article-title":"Opposing time trends of peptic ulcer and reflux disease","volume":"43","author":"El-Serag","year":"1998","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib13","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1136\/bmj.326.7392.737","article-title":"Prevalence of Helicobacter pylori in patients with gastro-esophageal reflux disease: a systematic review","volume":"326","author":"Raghunath","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.gtc.2007.07.014_bib14","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1136\/gut.41.3.277","article-title":"Helicobacter pylori in gastro-oesophageal reflux disease: causal agent, independent or protective factor?","volume":"41","author":"Labenz","year":"1997","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib15","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1053\/gast.2002.30301","article-title":"Gastroesophageal reflux disease in monozygotic and dizygotic twins","volume":"122","author":"Cameron","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib16","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1136\/gut.52.8.1085","article-title":"Genetic influences in gastro-oesophageal reflux disease: a twin study","volume":"52","author":"Mohammed","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib17","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1001\/jama.284.3.325","article-title":"Mapping of a gene for severe pediatric reflux disease on chromosome 13q14","volume":"284","author":"Hu","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.gtc.2007.07.014_bib18","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1080\/003655298750026697","article-title":"The usefulness of a structured questionnaire in the assessment of symptomatic gastroesophageal reflux disease","volume":"33","author":"Carlsson","year":"1998","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib19","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1111\/j.1572-0241.2003.07531.x","article-title":"Nighttime heartburn is an under-appreciated clinical problem that impacts sleep and daytime function: the results of a Gallup survey conducted on behalf of the American Gastroenterological Association","volume":"98","author":"Shaker","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0016-5085(82)80286-2","article-title":"Acid neutralizing capacity of human saliva","volume":"83","author":"Helm","year":"1987","journal-title":"Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib21","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1001\/jama.295.13.1566","article-title":"Can the clinical history distinguish between organic and functional dyspepsia?","volume":"295","author":"Moayyedi","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.gtc.2007.07.014_bib22","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00004836-198702000-00006","article-title":"Esophageal acid sensitivity in Barrett's esophagus","volume":"9","author":"Johnson","year":"1987","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib23","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/00000441-200311000-00006","article-title":"Diagnostic tests for gastroesophageal reflux disease","volume":"326","author":"Richter","year":"2003","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.gtc.2007.07.014_bib24","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/S1052-5157(18)30475-6","article-title":"Severe reflux esophagitis","volume":"4","author":"Richter","year":"1994","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"10.1016\/j.gtc.2007.07.014_bib25","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0016-5107(04)01555-X","article-title":"Classification of esophagitis: who needs it?","volume":"60","author":"Nayer","year":"2004","journal-title":"Gastrointestinal Endoscopy"},{"key":"10.1016\/j.gtc.2007.07.014_bib26","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1136\/gut.45.2.172","article-title":"Endoscopic assessment of oesophagitis: clinical and functional correlation and further validation of the Los Angeles classification","volume":"45","author":"Lundell","year":"1999","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib27","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1111\/j.1572-0241.2006.00829.x","article-title":"Prospective follow-up from the ProGERD study suggests that GERD is not a categorical disease","volume":"101","author":"Labenz","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib28","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1111\/j.1572-0241.2004.40502.x","article-title":"Clinical impact of upper endoscopy in the management of patients with gastroesophageal reflux disease","volume":"99","author":"Wo","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib29","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/j.1572-0241.2005.41217.x","article-title":"American College of Gastroenterology updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease","volume":"100","author":"DeVault","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib30","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.cgh.2006.08.006","article-title":"Microscopic esophageal mucosal injury in non-erosive reflux disease","volume":"5","author":"Dent","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2007.07.014_bib31","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1053\/j.gastro.2004.08.014","article-title":"The pathogenesis of heartburn in non-erosive disease: a unifying hypothesis","volume":"128","author":"Barlow","year":"2005","journal-title":"Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib32","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1046\/j.1365-2036.2003.01713.x","article-title":"Dilated intercellular spaces as a marker of esophageal damage: comparative results in GERD with or without bile reflux","volume":"18","author":"Cavigilia","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.gtc.2007.07.014_bib33","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1007\/BF01535789","article-title":"Ambulatory 24-hour esophageal pH monitoring: reproducibility and variability of pH parameters","volume":"33","author":"Wiener","year":"1988","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.gtc.2007.07.014_bib34","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1053\/gast.1996.1101982","article-title":"Clinical esophageal pH recording: a technical review for practice guideline development","volume":"110","author":"Kahrilas","year":"1996","journal-title":"Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib35","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/j.1572-0241.2003.07398.x","article-title":"Ambulatory esophageal pH monitoring using a wireless system","volume":"94","author":"Pandolfino","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib36","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S1542-3565(05)00021-2","article-title":"Value of extended recording time with wireless pH monitoring in evaluating gastroesophageal reflux disease","volume":"3","author":"Prakash","year":"2005","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2007.07.014_bib37","unstructured":"US Food and Drug Administration, Center for Devices and Radiologic Health. Available at: http:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfMAUDE\/search.cfm. Accessed February 2, 2007."},{"key":"10.1016\/j.gtc.2007.07.014_bib38","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1572-0241.2006.00966.x","article-title":"Technology review: esophageal impedance monitoring","volume":"102","author":"Bredenoord","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib39","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1111\/j.1572-0241.2006.00711.x","article-title":"Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy","volume":"101","author":"Zerbid","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib40","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1136\/gut.2005.087668","article-title":"Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy. A multicenter study using combined ambulatory impedance-pH monitoring","volume":"55","author":"Mainie","year":"2006","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib41","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/gut.2004.055418","article-title":"Weakly acidic reflux in patients with chronic unexplained cough during 24 hour pressure, pH and impedance monitoring","volume":"54","author":"Sifrim","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib42","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/0016-5085(86)90692-X","article-title":"Esophageal peristaltic dysfunction in peptic esophagitis","volume":"91","author":"Kahrilas","year":"1986","journal-title":"Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib43","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1007\/s00464-001-8327-z","article-title":"Total fundoplication is the operation of choice for patients with gastroesophageal reflux and defective peristalsis","volume":"16","author":"Oleynikov","year":"2002","journal-title":"Surg Endosc"},{"key":"10.1016\/j.gtc.2007.07.014_bib44","first-page":"230","article-title":"Classification of the esophageal function defect in patients with manometric ineffective esophageal motility: studies using combined impedance-manometry","volume":"2","author":"Tutuian","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib45","doi-asserted-by":"crossref","first-page":"518","DOI":"10.7326\/0003-4819-140-7-200404060-00011","article-title":"Short-term treatment with PPIs as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics","volume":"140","author":"Numans","year":"2004","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib46","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0016-5085(98)70363-4","article-title":"The clinical and economic value of a short course of omeprazole in patients with non-cardiac chest pain","volume":"115","author":"Fass","year":"1998","journal-title":"Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib47","first-page":"1901","article-title":"Gastroesophageal reflux disease\u2014should we adopt a new conceptual framework?","volume":"97","author":"Fass","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib48","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1111\/j.1572-0241.2006.00631.x","article-title":"Detection of Barrett's esophagus after endoscopic healing of erosive esophagitis","volume":"101","author":"Hanna","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib49","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0889-8553(05)70095-9","article-title":"Peptic strictures of the esophagus","volume":"28","author":"Richter","year":"1999","journal-title":"Gastroenterol Clin North Am"},{"key":"10.1016\/j.gtc.2007.07.014_bib50","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1001\/archinte.150.8.1669","article-title":"Gastroesophageal reflux as a pathogenic factor in the development of symptomatic lower esophageal rings","volume":"150","author":"Marshall","year":"1990","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/gut.53.suppl_1.i1","article-title":"Guidelines on the use of esophageal dilatation in clinical practice","volume":"55","author":"Riley","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib52","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1136\/gut.34.2.152","article-title":"Oesophagitis is as important as oesophageal stricture diameter in determining dysphagia","volume":"34","author":"Dakkak","year":"1993","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib53","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1053\/gast.1996.v111.pm8898632","article-title":"Role of acid and duodenogastroesophageal reflux in gastroesophageal reflux disease","volume":"111","author":"Vaezi","year":"1996","journal-title":"Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib54","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1053\/j.gastro.2006.08.032","article-title":"The development and validation of an endoscopic grading system for Barrett's esophagus: the Prague C&M criteria","volume":"131","author":"Sharma","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib55","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1001\/jama.287.15.1972","article-title":"Gastroesophageal reflux Barrett's esophagus and esophageal cancer: scientific review","volume":"287","author":"Shaheen","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.gtc.2007.07.014_bib56","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1056\/NEJM199903183401101","article-title":"Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma","volume":"340","author":"Lagergren","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib57","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1053\/j.gastro.2004.04.010","article-title":"A critical review of the diagnosis and management of Barrett's esophagram: the AGA Chicago workshop","volume":"127","author":"Sharma","year":"2004","journal-title":"Gastroenterology"},{"issue":"Suppl 1","key":"10.1016\/j.gtc.2007.07.014_bib58","first-page":"1","article-title":"Barrett's oesophagus and oesophageal adenocarcinoma","volume":"54","author":"Pallone","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib59","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1097\/00042737-200409000-00004","article-title":"Ear, nose and throat and respiratory manifestations of gastro-oesophageal reflux disease: an increasing conundrum","volume":"16","author":"Richter","year":"2004","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2007.07.014_bib60","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0002-9343(05)80008-7","article-title":"Twenty-four hour esophageal pH monitoring. The most useful test for evaluating non-cardiac chest pain","volume":"90","author":"Hewson","year":"1991","journal-title":"Am J Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib61","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0016-5085(99)70225-8","article-title":"Sustained esophageal contraction: a marker of esophageal chest pain identified by intraluminal ultrasonography","volume":"116","author":"Balaban","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib62","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1001\/archinte.166.9.965","article-title":"Are lifestyle measures effective in patients with gastroesophageal reflux disease? An evidence-based approach","volume":"166","author":"Kaltenback","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib63","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.1365-2036.2006.03135.x","article-title":"Meta-analysis: the efficacy of over-the-counter gastro-oesophageal reflux disease therapies","volume":"25","author":"Tran","year":"2006","journal-title":"Ailment Pharmacol Ther"},{"key":"10.1016\/j.gtc.2007.07.014_bib64","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1016\/S0140-6736(06)68932-0","article-title":"Gastroesophageal reflux disease","volume":"367","author":"Moayyedi","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.gtc.2007.07.014_bib65","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002095.pub2","article-title":"Short term treatment with proton pump inhibitors, H2RAs and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease","volume":"3","author":"van Pinxteren","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.gtc.2007.07.014_bib66","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003245.pub2","article-title":"Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease","volume":"3","author":"Donnellan","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.gtc.2007.07.014_bib67","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.cgh.2006.09.013","article-title":"Esomeprazole versus other proton pump inhibitors in erosive esophagitis: a meta-analysis of randomized clinical trials","volume":"4","author":"Gralnek","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2007.07.014_bib68","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1111\/j.1572-0241.2006.00828.x","article-title":"Esophageal stricture: incidence, treatment patterns and recurrence rate","volume":"101","author":"Ruigomez","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib69","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1111\/j.1572-0241.2005.41184.x","article-title":"Long-term acid suppression therapy may prevent the relapse of lower esophageal (Schatzki's) rings: a prospective, randomized, placebo-controlled study","volume":"100","author":"Sgouros","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib70","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1111\/j.1572-0241.2005.41657.x","article-title":"Diagnostic and therapeutic use of proton pump inhibitors in non-cardiac chest pain: a meta-analysis","volume":"100","author":"Cremmini","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib71","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1001\/archinte.165.11.1222","article-title":"Is proton pump inhibitor testing an effective approach to diagnose gastroesophageal reflux disease in patients with non-cardiac chest pain? A meta-analysis","volume":"165","author":"Wang","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib72","article-title":"Gastroesophageal reflux disease for prolonged non-specific cough in children and adults","volume":"2","author":"Chang","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.gtc.2007.07.014_bib73","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD001496","article-title":"Gastro-oesophageal reflux treatment for adults and children with asthma","volume":"1","author":"Gibson","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.gtc.2007.07.014_bib74","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1111\/j.1572-0241.2006.00844.x","article-title":"Proton pump inhibitor therapy suspected GERD-related chronic laryngitis: a meta-analysis of randomized controlled trials","volume":"101","author":"Qadeer","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib75","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1111\/j.1572-0241.2005.00285.x","article-title":"Effect of esomeprazole on nighttime heartburn and sleep quality in patients with GERD: a randomized, placebo-controlled trial","volume":"100","author":"Johnson","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib76","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0002-9343(01)00901-9","article-title":"Patterns of proton pump inhibitors in clinical practice","volume":"111","author":"Barrison","year":"2001","journal-title":"Am J Med"},{"key":"10.1016\/j.gtc.2007.07.014_bib77","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/S1542-3565(05)00860-8","article-title":"Treatment of patients with persistent heartburn symptoms: a double-blind randomized trial","volume":"4","author":"Fass","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2007.07.014_bib78","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1046\/j.1365-2036.2003.01423.x","article-title":"Non-erosive reflux disease, acid reflux and symptom pattern","volume":"17","author":"Martinez","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.gtc.2007.07.014_bib79","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1442-2050.2006.00619.x","article-title":"The patient with refractory gastroesophageal reflux disease","volume":"19","author":"Richter","year":"2006","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.gtc.2007.07.014_bib80","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1111\/j.1365-2036.2006.03127.x","article-title":"Increased risk of fundic gland polyps during long-term proton pump inhibitor therapy","volume":"24","author":"Jalving","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.gtc.2007.07.014_bib81","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1001\/jama.292.16.1955","article-title":"Risk of community-acquired pneumonia and use of gastric acid-suppression drugs","volume":"292","author":"Laheij","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.gtc.2007.07.014_bib82","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1111\/j.1572-0241.2007.01275.x","article-title":"Systemic review of the risk of enteric infections in patients taking acid suppression","volume":"102","author":"Leonard","year":"2007","journal-title":"Am J Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib83","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1001\/jama.296.24.2947","article-title":"Long-term proton pump inhibitor therapy and risk of hip fracture","volume":"296","author":"Yang","year":"2006","journal-title":"JAMA"},{"key":"10.1016\/j.gtc.2007.07.014_bib84","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.thorsurg.2005.03.002","article-title":"New investigational therapies for gastroesophageal reflux disease","volume":"15","author":"Richter","year":"2005","journal-title":"Thorac Surg Clin"},{"key":"10.1016\/j.gtc.2007.07.014_bib85","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1136\/gut.52.4.464","article-title":"Effect of acute and chronic administration of the GABA B agonist baclofen on 24 hr pH-metry and symptoms in control subjects and patients with gastro-oesophageal reflux disease","volume":"52","author":"Ciccaglione","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib86","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1136\/gut.52.10.1397","article-title":"Effect of the GABA B agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors","volume":"52","author":"Koek","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2007.07.014_bib87","article-title":"AGA Institute Technical Review on the use of endoscopic therapy for gastroesophageal reflux disease","volume":"131","author":"Falk","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib88","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1053\/j.gastro.2006.07.004","article-title":"Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease: a randomized, sham-controlled trail","volume":"131","author":"Rothstein","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib89","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S1521-6918(03)00101-X","article-title":"Laparoscopic treatment of gastro-oesophageal reflux disease","volume":"18","author":"Watson","year":"2004","journal-title":"Best Practice and Research Clinical Gastroenterology"},{"key":"10.1016\/j.gtc.2007.07.014_bib90","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.cgh.2005.12.019","article-title":"Complications and anti-reflux medication use after antireflux surgery","volume":"4","author":"Dominitz","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2007.07.014_bib91","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1080\/110241500750008475","article-title":"Medical or surgical treatment for chronic gastroesophageal reflux? A systematic review of the published evidence of effectiveness","volume":"166","author":"Allgood","year":"2000","journal-title":"Eur J Surg"},{"key":"10.1016\/j.gtc.2007.07.014_bib92","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1111\/j.1572-0241.2005.41007.x","article-title":"Fundoplication and the risk of esophageal cancer in gastroesophageal reflux disease: a Veterans Affair Cohort Study","volume":"100","author":"Tran","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2007.07.014_bib93","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S1072-7515(00)00797-3","article-title":"Continued (5 yr) follow-up of a randomized clinical study comparing antireflux surgery and omeprazole in gastroesophageal reflux disease","volume":"192","author":"Lundell","year":"2001","journal-title":"J\u00a0Am Coll Surg"},{"key":"10.1016\/j.gtc.2007.07.014_bib94","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/j.amjsurg.2004.08.062","article-title":"Failed fundoplication","volume":"188","author":"Hatch","year":"2004","journal-title":"Am J Surg"}],"container-title":["Gastroenterology Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088985530700074X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S088985530700074X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T04:27:57Z","timestamp":1708489677000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S088985530700074X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":94,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["S088985530700074X"],"URL":"https:\/\/doi.org\/10.1016\/j.gtc.2007.07.014","relation":{},"ISSN":["0889-8553"],"issn-type":[{"value":"0889-8553","type":"print"}],"subject":[],"published":{"date-parts":[[2007,9]]}}}