{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:56:54Z","timestamp":1774357014726,"version":"3.50.1"},"reference-count":81,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T00:00:00Z","timestamp":1212278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Clinics of North America"],"published-print":{"date-parts":[[2008,6]]},"DOI":"10.1016\/j.gtc.2008.02.007","type":"journal-article","created":{"date-parts":[[2008,5,21]],"date-time":"2008-05-21T19:14:27Z","timestamp":1211397267000},"page":"383-395","source":"Crossref","is-referenced-by-count":16,"title":["Functional Gastrointestinal Disorders and the Potential Role of Eosinophils"],"prefix":"10.1016","volume":"37","author":[{"given":"Marjorie M.","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas J.","family":"Talley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.gtc.2008.02.007_bib1","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1053\/j.gastro.2006.03.008","article-title":"The functional gastrointestinal disorders and the Rome III process","volume":"130","author":"Drossman","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib2","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1542-3565(05)00981-X","article-title":"Health-related quality of life in patients attending a gastroenterology outpatient clinic: functional disorders versus organic diseases","volume":"4","author":"Simren","year":"2006","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2008.02.007_bib3","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1365-2036.2007.03370.x","article-title":"Costs of health care for irritable bowel syndrome, chronic constipation, functional diarrhoea and functional abdominal pain","volume":"26","author":"Nyrop","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.gtc.2008.02.007_bib4","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1053\/j.gastro.2006.10.026","article-title":"Neuroimaging of the brain-gut axis: from basic understanding to treatment of functional GI disorders","volume":"131","author":"Mayer","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1365-2982.2005.00730.x","article-title":"Brain-gut connections in functional GI disorders: anatomic and physiologic relationships","volume":"18","author":"Jones","year":"2006","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.gtc.2008.02.007_bib6","doi-asserted-by":"crossref","first-page":"698","DOI":"10.7326\/0003-4819-121-9-199411010-00011","article-title":"NIH conference. Asthma","volume":"121","author":"Goldstein","year":"1994","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.gtc.2008.02.007_bib7","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1067\/mai.2001.120095","article-title":"Pathogenesis and clinical features of eosinophilic esophagitis","volume":"108","author":"Rothenberg","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib8","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.cgh.2007.05.015","article-title":"Non-ulcer dyspepsia and duodenal eosinophilia: an adult endoscopic population-based case-control study","volume":"5","author":"Talley","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2008.02.007_bib9","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1177\/000992280604500205","article-title":"Mucosal eosinophilia and response to H1\/H2 antagonist and cromolyn therapy in pediatric dyspepsia","volume":"45","author":"Friesen","year":"2006","journal-title":"Clin Pediatr (Phila)"},{"key":"10.1016\/j.gtc.2008.02.007_bib10","first-page":"110","article-title":"A quantitative evaluation of mucosal eosinophils in the pediatric gastrointestinal tract","volume":"9","author":"Lowichik","year":"1996","journal-title":"Mod Pathol"},{"key":"10.1016\/j.gtc.2008.02.007_bib11","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s10620-005-1586-0","article-title":"Evaluation of mucosal eosinophils in the pediatric colon","volume":"50","author":"Pensabene","year":"2005","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.gtc.2008.02.007_bib12","first-page":"363","article-title":"Geographic variations in eosinophil concentration in normal colonic mucosa","volume":"10","author":"Pascal","year":"1997","journal-title":"Mod Pathol"},{"key":"10.1016\/j.gtc.2008.02.007_bib13","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/j.cgh.2007.07.025","article-title":"An eosinophil hypothesis for functional dyspepsia","volume":"5","author":"Rothenberg","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2008.02.007_bib14","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1136\/adc.82.2.131","article-title":"Gastrointestinal symptoms in patients with asthma","volume":"82","author":"Caffarelli","year":"2000","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.gtc.2008.02.007_bib15","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1136\/adc.78.3.230","article-title":"Gastrointestinal symptoms in atopic eczema","volume":"78","author":"Caffarelli","year":"1998","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.gtc.2008.02.007_bib16","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1136\/pgmj.2006.049585","article-title":"Increased prevalence of gastrointestinal symptoms in patients with allergic disease","volume":"83","author":"Powell","year":"2007","journal-title":"Postgrad Med J"},{"issue":"Suppl 1","key":"10.1016\/j.gtc.2008.02.007_bib17","doi-asserted-by":"crossref","first-page":"S100","DOI":"10.1016\/S0091-6749(02)81405-1","article-title":"Dyspepsia is associated with allergic rhinitis","volume":"109","author":"Powell","year":"2002","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib18","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1084\/jem.182.6.1897","article-title":"Immunoreactivity for interleukin 3 and 5 granulocyte\/macrophage colony-stimulating factor of intestinal mucosa in bronchial asthma","volume":"182","author":"Wallaert","year":"1995","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.gtc.2008.02.007_bib19","first-page":"253","article-title":"Small bowel of patients with asthma and allergic rhinitis: absence of inflammation despite the presence of major cellular components of allergic inflammation","volume":"25","author":"Pires","year":"2004","journal-title":"Allergy Asthma Proc"},{"key":"10.1016\/j.gtc.2008.02.007_bib20","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/j.1398-9995.1996.tb04471.x","article-title":"Prevalence of adverse reactions to food in patients with gastrointestinal disease","volume":"51","author":"Bischoff","year":"1996","journal-title":"Allergy"},{"key":"10.1016\/j.gtc.2008.02.007_bib21","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1111\/j.1572-0241.2003.07484.x","article-title":"Functional and morphologic characterization of eosinophils in the lower intestinal mucosa of patients with food allergy","volume":"98","author":"Schwab","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib22","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1111\/j.1365-2982.2005.00745.x","article-title":"Is there a role of food allergy in irritable bowel syndrome and functional dyspepsia? A systematic review","volume":"18","author":"Park","year":"2006","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.gtc.2008.02.007_bib23","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1111\/j.1572-0241.2005.41348.x","article-title":"Food-specific serum IgG4 and IgE titers to common food antigens in irritable bowel syndrome","volume":"100","author":"Zar","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib24","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/j.1365-2222.2007.02727.x","article-title":"Alterations of food antigen-specific serum immunoglobulins G\u00a0and E antibodies in patients with irritable bowel syndrome and functional dyspepsia","volume":"37","author":"Zuo","year":"2007","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.gtc.2008.02.007_bib25","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1136\/gut.47.6.804","article-title":"Increased rectal mucosal enteroendocrine cells, T.\u00a0lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome","volume":"47","author":"Spiller","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2008.02.007_bib26","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1053\/j.gastro.2005.04.012","article-title":"Dyspepsia and irritable bowel syndrome after a Salmonella gastroenteritis outbreak: one-year follow-up cohort study","volume":"129","author":"Mearin","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib27","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1053\/gast.2002.33663","article-title":"Clinical and pathophysiological characteristics of acute-onset functional dyspepsia","volume":"122","author":"Tack","year":"2002","journal-title":"Gastroenterology"},{"issue":"Suppl 17","key":"10.1016\/j.gtc.2008.02.007_bib28","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00535-006-1925-8","article-title":"Role of infection in irritable bowel syndrome","volume":"42","author":"Spiller","year":"2007","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib29","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1053\/j.gastro.2003.09.028","article-title":"Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS","volume":"125","author":"Dunlop","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib31","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1053\/j.gastro.2004.05.030","article-title":"Pathophysiology and treatment of functional dyspepsia","volume":"127","author":"Tack","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib32","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1157\/13078993","article-title":"CagA status and Helicobacter pylori eradication among dyspeptic patients","volume":"28","author":"Magalh\u00e3es","year":"2005","journal-title":"Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2008.02.007_bib33","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1046\/j.1365-2982.2000.00221.x","article-title":"Increased mast cells in the irritable bowel syndrome","volume":"12","author":"O'Sullivan","year":"2000","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.gtc.2008.02.007_bib34","first-page":"485","article-title":"Impaired small intestinal peristaltic reflexes and sensory thresholds are independent functional disturbances in patients with chronic unexplained dyspepsia","volume":"91","author":"Holtmann","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib35","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1111\/j.1572-0241.2004.30822.x","article-title":"A pilot study on duodenal acid exposure and its relationship to symptoms in functional dyspepsia with prominent nausea","volume":"99","author":"Lee","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib36","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1080\/00365520410008141","article-title":"Valid symptom reporting at upper endoscopy in a random sample of the Swedish adult general population: the Kalixanda study","volume":"39","author":"Aro","year":"2004","journal-title":"Scand J\u00a0Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib37","first-page":"A73","article-title":"Duodenal eosinophilia and mast cell infiltration in functional dyspepsia (FD) and irritable bowel syndrome (IBS): duodenal eosinophilia a biomarker for FD but not IBS in adults?","volume":"132","author":"Talley","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib38","first-page":"pe26","article-title":"Differential secretion of cytokines","volume":"338","author":"Moqbel","year":"2006","journal-title":"Sci STKE"},{"issue":"Suppl 1","key":"10.1016\/j.gtc.2008.02.007_bib39","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000053634","article-title":"Regulation of human eotaxin generation by Th1-\/Th2-derived cytokines","volume":"122","author":"Miyamasu","year":"2000","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib40","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1126\/science.3110954","article-title":"Eosinophils co-cultured with endothelial cells have increased survival and functional properties","volume":"237","author":"Rothenberg","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.gtc.2008.02.007_bib41","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S1357-4310(99)01635-4","article-title":"Eotaxin and eosinophil recruitment: implications for human disease","volume":"6","author":"Rankin","year":"2000","journal-title":"Mol Med Today"},{"key":"10.1016\/j.gtc.2008.02.007_bib42","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1067\/mai.2003.139","article-title":"Chemokines in asthma: cooperative interaction between chemokines and IL-13","volume":"111","author":"Zimmermann","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib43","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1038\/86365","article-title":"A pathological function for eotaxin and eosinophils in eosinophilic gastrointestinal inflammation","volume":"2","author":"Hogan","year":"2001","journal-title":"Nat Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib44","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1172\/JCI10224","article-title":"An etiological role for aeroallergens and eosinophils in experimental esophagitis","volume":"107","author":"Mishra","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1016\/j.gtc.2008.02.007_bib45","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.gastro.2003.07.007","article-title":"Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism","volume":"125","author":"Mishra","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib46","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1172\/JCI26679","article-title":"Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis","volume":"116","author":"Blanchard","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.gtc.2008.02.007_bib47","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1111\/j.1572-0241.1998.440_j.x","article-title":"Evidence of a genetic contribution to functional bowel disorder","volume":"93","author":"Morris-Yates","year":"1998","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib48","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1053\/gast.2001.27995","article-title":"Irritable bowel syndrome in twins: heredity and social learning both contribute to etiology","volume":"121","author":"Levy","year":"2001","journal-title":"Gastroenterology"},{"issue":"25","key":"10.1016\/j.gtc.2008.02.007_bib49","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1111\/j.1365-2036.2007.03326.x","article-title":"Influence of genetics on irritable bowel syndrome, gastro-oesophageal reflux and dyspepsia: a twin study","volume":"1","author":"Lembo","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.gtc.2008.02.007_bib50","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1572-0241.2006.00481.x","article-title":"A study of candidate genotypes associated with dyspepsia in a U.S. community","volume":"101","author":"Camilleri","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib51","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1053\/j.gastro.2004.01.006","article-title":"G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia","volume":"126","author":"Holtmann","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib52","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/j.1572-0241.2006.00480.x","article-title":"Hypothesis driven research and molecular mechanisms in functional dyspepsia: the beginning of a beautiful friendship in research and practice?","volume":"101","author":"Holtmann","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib53","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S1359-6101(03)00047-9","article-title":"New insights on the involvement of nerve growth factor in allergic inflammation and fibrosis","volume":"14","author":"Micera","year":"2003","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.gtc.2008.02.007_bib54","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1146\/annurev.immunol.24.021605.090720","article-title":"The eosinophil","volume":"24","author":"Rothenberg","year":"2006","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib55","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/S0091-6749(03)02014-1","article-title":"Indoleamine 2,3-dioxygenase-expressing antigen-presenting cells and peripheral T-cell tolerance: another piece to the atopic puzzle?","volume":"112","author":"von Bubnoff","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib56","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.3748\/wjg.v13.i16.2333","article-title":"Duodenal intraepithelial T lymphocytes in patients with functional dyspepsia","volume":"13","author":"Gargala","year":"2007","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib57","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1046\/j.1365-2249.1999.00827.x","article-title":"Functional expression of Fas and Fas ligand on human intestinal intraepithelial lymphocytes","volume":"116","author":"Morimoto","year":"1999","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib58","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1113\/jphysiol.2003.052274","article-title":"Acute stress modulates the histamine content of mast cells in the gastrointestinal tract through interleukin-1 and corticotropin-releasing factor release in rats","volume":"553","author":"Eutamene","year":"2003","journal-title":"J Physiol"},{"key":"10.1016\/j.gtc.2008.02.007_bib59","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1080\/00365520410009410","article-title":"Review\u2014Pathogenesis of irritable bowel syndrome: the mast cell connection","volume":"40","author":"Santos","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jneuroim.2003.10.041","article-title":"Critical role of mast cells in inflammatory diseases and the effect of acute stress","volume":"146","author":"Theoharides","year":"2004","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib61","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1136\/gut.2006.100594","article-title":"Diarrhoea-predominant IBS patients show mast cell activation and hyperplasia in the jejunum","volume":"56","author":"Guilarte","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.gtc.2008.02.007_bib62","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1007\/BF01303164","article-title":"Terminal ileal mucosal mast cells in irritable bowel syndrome","volume":"38","author":"Weston","year":"1993","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.gtc.2008.02.007_bib63","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1053\/j.gastro.2003.11.055","article-title":"Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome","volume":"126","author":"Barbara","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib64","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1053\/S1542-3565(03)00184-8","article-title":"Gastric mucosal mast cells are increased in Helicobacter pylori-negative functional dyspepsia","volume":"1","author":"Hall","year":"2003","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.gtc.2008.02.007_bib65","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1126\/science.7504324","article-title":"Activation of exocytosis by the heterotrimeric G-protein Gi3","volume":"262","author":"Aridor","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.gtc.2008.02.007_bib66","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/S0161-5890(02)00090-1","article-title":"Review\u2014Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation","volume":"38","author":"Piliponsky","year":"2001","journal-title":"Mol Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib67","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1016\/S0021-9258(17)41999-5","article-title":"Effect of nerve growth factor on rat peritoneal mast cells, survival promotion and immediate- early gene induction","volume":"269","author":"Horigome","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.gtc.2008.02.007_bib68","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1016\/S0091-6749(00)90623-7","article-title":"Expression and functionality of death receptors on the human mast cell line HMC-1","volume":"105","author":"Piliponsky","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib69","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/01.mog.0000194792.36466.5c","article-title":"Post-infectious irritable bowel syndrome","volume":"22","author":"Spiller","year":"2006","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1016\/j.gtc.2008.02.007_bib70","doi-asserted-by":"crossref","first-page":"2410","DOI":"10.4049\/jimmunol.163.5.2410","article-title":"Direct neurite\u2013mast cell communication in vitro occurs via the neuropeptide substance P","volume":"163","author":"Suzuki","year":"1999","journal-title":"J Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib71","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1365-2982.2004.00502.x","article-title":"Substance P and other neuropeptides do not induce mediator release in isolated human intestinal mast cells","volume":"16","author":"Bischoff","year":"2004","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.gtc.2008.02.007_bib72","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.autneu.2006.01.002","article-title":"Vagal influences over mast cells","volume":"125","author":"Stead","year":"2006","journal-title":"Auton Neurosci"},{"key":"10.1016\/j.gtc.2008.02.007_bib73","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1159\/000097346","article-title":"Vagal afferent nerve fibres contact mast cells in rat small intestinal mucosa","volume":"4","author":"Williams","year":"1997","journal-title":"Neuroimmunomodulation"},{"key":"10.1016\/j.gtc.2008.02.007_bib74","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1046\/j.1365-2982.1997.d01-4.x","article-title":"Effect of truncal vagotomy and capsaicin on mast cells and IgA- positive plasma cells in rat cells in rat jejunal mucosa","volume":"9","author":"Gottwald","year":"1997","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.gtc.2008.02.007_bib75","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1053\/j.gastro.2006.11.002","article-title":"The serotonin signaling system: from basic understanding to drug development for functional GI disorders","volume":"132","author":"Gershon","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib76","first-page":"S25","article-title":"Serotonin and its implication for the management of irritable bowel syndrome","volume":"3","author":"Gershon","year":"2003","journal-title":"Rev Gastroenterol Disord"},{"key":"10.1016\/j.gtc.2008.02.007_bib77","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.4049\/jimmunol.173.6.3599","article-title":"Cutting edge: serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin","volume":"173","author":"Boehme","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib78","doi-asserted-by":"crossref","first-page":"6422","DOI":"10.4049\/jimmunol.177.9.6422","article-title":"5-hydroxytryptamine induces mast cell adhesion and migration","volume":"177","author":"Kushnir-Sukhov","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib79","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.jaci.2006.09.003","article-title":"Human mast cells are capable of serotonin synthesis and release","volume":"119","author":"Kushnir-Sukhov","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib80","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1053\/j.gastro.2005.02.011","article-title":"Serotonin inhibits Na+\/H+ exchange activity via 5-HT4\u00a0receptors and activation of PKC alpha in human intestinal epithelial cells","volume":"128","author":"Gill","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.gtc.2008.02.007_bib81","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jaci.2003.10.047","article-title":"Eosinophilic gastrointestinal disorders (EGID)","volume":"113","author":"Rothenberg","year":"2004","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.gtc.2008.02.007_bib82","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/S1542-3565(05)00885-2","article-title":"Eosinophilic esophagitis: a 10-year experience in 381 children","volume":"3","author":"Liacouras","year":"2005","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Gastroenterology Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889855308000198?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889855308000198?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T13:07:46Z","timestamp":1684415266000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889855308000198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":81,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["S0889855308000198"],"URL":"https:\/\/doi.org\/10.1016\/j.gtc.2008.02.007","relation":{},"ISSN":["0889-8553"],"issn-type":[{"value":"0889-8553","type":"print"}],"subject":[],"published":{"date-parts":[[2008,6]]}}}