{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:30:47Z","timestamp":1791401447514,"version":"4.3.3"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000030","name":"U.S. Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["UO1EH000421"],"award-info":[{"award-number":["UO1EH000421"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Harmful Algae"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.hal.2016.03.009","type":"journal-article","created":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T18:44:58Z","timestamp":1472841898000},"page":"35-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"PB","title":["Gene expression patterns in peripheral blood leukocytes in patients with recurrent ciguatera fish poisoning: Preliminary studies"],"prefix":"10.1016","volume":"57","author":[{"given":"Maria-Cecilia","family":"Lopez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo F.","family":"Ungaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry V.","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyle L.","family":"Moldawer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Abbott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sparkle M.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn M.","family":"Grattan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"J. Glenn","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.hal.2016.03.009_bib0005","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.4269\/ajtmh.1979.28.1067","article-title":"Clinical observations on 3009 cases of ciguatera (fish poisoning) in the South Pacific","volume":"28","author":"Bagnis","year":"1979","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"6","key":"10.1016\/j.hal.2016.03.009_bib0010","doi-asserted-by":"crossref","first-page":"e5805","DOI":"10.1371\/journal.pone.0005805","article-title":"Gene expression in peripheral blood leukocytes in monozygotic twins discordant for chronic fatigue: no evidence of a biomarker","volume":"4","author":"Byrnes","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.hal.2016.03.009_bib0015","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1038\/nature04244","article-title":"Mapping determinants of human gene expression by regional and genome-wide association","volume":"437","author":"Cheung","year":"2005","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.hal.2016.03.009_bib0020","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0016-5085(91)90218-A","article-title":"Diarrhea in ciguatera fish poisoning: preliminary evaluation of pathophysiological mechanisms","volume":"100","author":"Fasano","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1016\/j.hal.2016.03.009_bib0025","series-title":"Harmful Algae","first-page":"245","article-title":"Seafood toxin diseases: issues in epidemiology and community outreach","author":"Fleming","year":"1998"},{"issue":"9","key":"10.1016\/j.hal.2016.03.009_bib0030","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/0041-0101(93)90130-B","article-title":"Study of factors that influence the clinical-response to ciguatera fish poisoning","volume":"31","author":"Glaziou","year":"1993","journal-title":"Toxicon"},{"issue":"8","key":"10.1016\/j.hal.2016.03.009_bib0035","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1136\/jcp.2005.025718","article-title":"Gene expression in peripheral blood mononuclear cells from patients with chronic fatigue syndrome","volume":"58","author":"Kaushik","year":"2005","journal-title":"J. Clin. Pathol."},{"issue":"3 Pt 1","key":"10.1016\/j.hal.2016.03.009_bib0040","doi-asserted-by":"crossref","first-page":"574","DOI":"10.4269\/ajtmh.1982.31.574","article-title":"Ciguatera fish poisoning: epidemiology of the disease on St. Thomas, U.S. Virgin Islands","volume":"31","author":"Morris","year":"1982","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.hal.2016.03.009_bib1040","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1001\/archinte.1982.00340190046008","article-title":"Clinical features of ciguatera fish poisoning: A study of the disease in the U.S Virgin Islands","volume":"142","author":"Morris","year":"1982","journal-title":"Arch. Intern. Med."},{"issue":"6","key":"10.1016\/j.hal.2016.03.009_bib0045","doi-asserted-by":"crossref","first-page":"309","DOI":"10.5694\/j.1326-5377.1997.tb122320.x","article-title":"Chronic fatigue syndrome: chronic ciguatera poisoning as a differential diagnosis","volume":"166","author":"Pearn","year":"1997","journal-title":"Med. J. Aust."},{"issue":"5","key":"10.1016\/j.hal.2016.03.009_bib0050","doi-asserted-by":"crossref","first-page":"908","DOI":"10.4269\/ajtmh.12-0676","article-title":"Ciguatera incidence in the U.S. Virgin Islands has not increased over a 30 year time period, despite rising seawater temperatures","volume":"88","author":"Radke","year":"2013","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"12","key":"10.1016\/j.hal.2016.03.009_bib0055","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/SMJ.0000000000000023","article-title":"Association of cardiac disease and alcohol use with the development of severe ciguatera","volume":"106","author":"Radke","year":"2013","journal-title":"South. Med. J."},{"key":"10.1016\/j.hal.2016.03.009_bib0060","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1186\/1471-2202-11-107","article-title":"Gene expression profiling in brain of mice exposed to the marine neurotoxin ciguatoxin reveals an acute anti-infloammatory, neuroprotective response","volume":"11","author":"Ryan","year":"2010","journal-title":"BMC Neurosci."},{"issue":"4","key":"10.1016\/j.hal.2016.03.009_bib0065","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1155\/2002\/892374","article-title":"Utility of the blood for gene expression profiling and biomarker discovery in chronic fatigue syndrome","volume":"18","author":"Vernon","year":"2002","journal-title":"Dis. Markers"}],"container-title":["Harmful Algae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568988316300671?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1568988316300671?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T17:23:41Z","timestamp":1582565021000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1568988316300671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":14,"alternative-id":["S1568988316300671"],"URL":"https:\/\/doi.org\/10.1016\/j.hal.2016.03.009","relation":{},"ISSN":["1568-9883"],"issn-type":[{"value":"1568-9883","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gene expression patterns in peripheral blood leukocytes in patients with recurrent ciguatera fish poisoning: Preliminary studies","name":"articletitle","label":"Article Title"},{"value":"Harmful Algae","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.hal.2016.03.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}